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  1. Article ; Online: Menopause as a window of opportunity: the benefits of designing more effective theory-driven behaviour change interventions to promote healthier lifestyle choices at midlife.

    Simpson, Ellen Elizabeth Anne / Doherty, Julie / Timlin, Deirdre

    The Proceedings of the Nutrition Society

    2023  , Page(s) 1–10

    Abstract: Menopause is a natural developmental phase that all women go through from their early forties to mid-fifties, marking the transition from the reproductive to the non-reproductive years. This is characterised as the permanent cessation of menses due to ... ...

    Abstract Menopause is a natural developmental phase that all women go through from their early forties to mid-fifties, marking the transition from the reproductive to the non-reproductive years. This is characterised as the permanent cessation of menses due to progressive ovarian failure. Each woman's experience of the menopause is unique. Biopsychosocial changes occur during this time with some symptoms affecting up to 80 % of women and lasting for 4-5 years from the peri- to post-menopause. Reduced oestrogen may predispose some women to health issues following menopause, such as heart disease, diabetes, stroke and cognitive decline. It is vital to understand how to promote health and well-being to reduce the risk of developing chronic conditions in later life. Increased symptoms and concerns about health during the menopausal transition can be cues to action for some women to actively maintain their health. Menopause represents a window of opportunity to promote health, and to support women to make healthier lifestyle choices, part of the National Institute for Clinical Excellence guidelines for menopause management. Identifying appropriate strategies to change behaviour is less clear. Theories of behaviour change can provide frameworks to gain more insight into the facilitators and barriers to behaviour and can inform the researcher on what needs to change. This information can be used to inform the design, content, implementation and evaluation of a lifestyle intervention. This review paper will explore the impact of menopause on health and well-being generally, and the benefits of designing more effective theory-driven behaviour change interventions for menopause.
    Language English
    Publishing date 2023-11-13
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 391142-1
    ISSN 1475-2719 ; 0029-6651
    ISSN (online) 1475-2719
    ISSN 0029-6651
    DOI 10.1017/S0029665123004810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Using the COM-B model to identify barriers and facilitators towards adoption of a diet associated with cognitive function (MIND diet).

    Timlin, Deirdre / McCormack, Jacqueline M / Simpson, Ellen Ea

    Public health nutrition

    2020  Volume 24, Issue 7, Page(s) 1657–1670

    Abstract: Objective: The aim of the study was to identify components of the COM-B (capability, opportunity, motivation and behaviour) model that influences behaviour to modify dietary patterns in 40-55-year-olds living in the UK, in order to influence the risk of ...

    Abstract Objective: The aim of the study was to identify components of the COM-B (capability, opportunity, motivation and behaviour) model that influences behaviour to modify dietary patterns in 40-55-year-olds living in the UK, in order to influence the risk of cognitive decline in later life.
    Design: This is a qualitative study using the COM-B model and theoretical domains framework (TDF) to explore beliefs to adopting the Mediterranean-DASH Intervention for Neurodegenerative delay (MIND) diet.
    Setting: Northern Ireland.
    Participants: Twenty-five participants were recruited onto the study to take part in either a focus group or an interview. Participants were men and women aged between 40 and 55 years. Participants were recruited via email, Facebook and face to face.
    Results: Content analysis revealed that the main perceived barriers to the adoption of the MIND diet were time, work environment, taste preference and convenience. The main perceived facilitators reported were improved health, memory, planning and organisation, and access to good quality food.
    Conclusions: This study provides insight into the personal, social and environmental factors that participants report as barriers and facilitators to the adoption of the MIND diet among middle-aged adults living in the UK. More barriers to healthy dietary change were found than facilitators. Future interventions that increase capability, opportunity and motivation may be beneficial. The results from this study will be used to design a behaviour change intervention using the subsequent steps from the Behaviour Change Wheel.
    MeSH term(s) Adult ; Cognition ; Diet, Mediterranean ; Dietary Approaches To Stop Hypertension ; Female ; Humans ; Male ; Middle Aged ; Motivation ; Workplace
    Language English
    Publishing date 2020-08-17
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1436024-x
    ISSN 1475-2727 ; 1368-9800
    ISSN (online) 1475-2727
    ISSN 1368-9800
    DOI 10.1017/S1368980020001445
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: A preliminary randomised control trial of the effects of Dru yoga on psychological well-being in Northern Irish first time mothers.

    Timlin, Deirdre / Simpson, Ellen Elizabeth Anne

    Midwifery

    2017  Volume 46, Page(s) 29–36

    Abstract: Background: the transition to motherhood can be stressful, especially for first time mothers. Recent research has shown that yoga can be effective for enhancing psychological well-being.: Objectives: the purpose of this study was to establish if a ... ...

    Abstract Background: the transition to motherhood can be stressful, especially for first time mothers. Recent research has shown that yoga can be effective for enhancing psychological well-being.
    Objectives: the purpose of this study was to establish if a postpartum Dru yoga intervention improves psychological well-being in first time mothers.
    Design: a randomised controlled study was conducted.
    Setting and participants: first time mothers were recruited from a Sure Start Community Centre and included in the study if they had a baby aged between 6 weeks to one-year-old. Exclusion criteria were the presence of sciatica, bulging discs, heart disease or whiplash and if they already practiced yoga.
    Methods: participants were randomised into a Dru yoga group (n=16) who received a one-hour Dru yoga session each week for 4 weeks and a 20-minute DVD for practice at home. The control group (n=16) who did not receive an intervention. Baseline and follow up measures of perceived stress, mood and coping were assessed in each group.
    Results: a repeated measures factorial Analysis of Variance showed that in comparison to the control group, the Dru yoga intervention group had improved psychological well-being as indicated by reductions in stress, negative affect, and dysfunctional coping and increases in problem focused coping at follow up (P<0.05).
    Conclusion: the current study shows that Dru yoga is beneficial for the psychological well-being of first time mothers. Further research is needed using large scale replication studies with a longer follow up period and including multiparous women. This study extends the support for yoga with postpartum mothers.
    MeSH term(s) Adult ; Female ; Humans ; Mothers/psychology ; Northern Ireland ; Patient Outcome Assessment ; Pregnancy ; Prospective Studies ; Quality of Life/psychology ; Stress, Psychological/complications ; Stress, Psychological/therapy ; Surveys and Questionnaires ; Yoga/psychology
    Language English
    Publishing date 2017-03
    Publishing country Scotland
    Document type Journal Article ; Randomized Controlled Trial
    ZDB-ID 1036567-9
    ISSN 1532-3099 ; 0266-6138
    ISSN (online) 1532-3099
    ISSN 0266-6138
    DOI 10.1016/j.midw.2017.01.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Using the COM-B model to identify barriers and facilitators towards adoption of a diet associated with cognitive function (MIND diet)

    Timlin, Deirdre / McCormack, Jacqueline M / Simpson, Ellen EA

    Public health nutrition. 2021 May, v. 24, no. 7

    2021  

    Abstract: The aim of the study was to identify components of the COM-B (capability, opportunity, motivation and behaviour) model that influences behaviour to modify dietary patterns in 40–55-year-olds living in the UK, in order to influence the risk of cognitive ... ...

    Abstract The aim of the study was to identify components of the COM-B (capability, opportunity, motivation and behaviour) model that influences behaviour to modify dietary patterns in 40–55-year-olds living in the UK, in order to influence the risk of cognitive decline in later life. This is a qualitative study using the COM-B model and theoretical domains framework (TDF) to explore beliefs to adopting the Mediterranean-DASH Intervention for Neurodegenerative delay (MIND) diet. Northern Ireland. Twenty-five participants were recruited onto the study to take part in either a focus group or an interview. Participants were men and women aged between 40 and 55 years. Participants were recruited via email, Facebook and face to face. Content analysis revealed that the main perceived barriers to the adoption of the MIND diet were time, work environment, taste preference and convenience. The main perceived facilitators reported were improved health, memory, planning and organisation, and access to good quality food. This study provides insight into the personal, social and environmental factors that participants report as barriers and facilitators to the adoption of the MIND diet among middle-aged adults living in the UK. More barriers to healthy dietary change were found than facilitators. Future interventions that increase capability, opportunity and motivation may be beneficial. The results from this study will be used to design a behaviour change intervention using the subsequent steps from the Behaviour Change Wheel.
    Keywords Northern Ireland ; behavior change ; behavior modification ; cognition ; cognitive disorders ; diet ; e-mail ; focus groups ; food choices ; memory ; models ; motivation ; public health ; qualitative analysis ; risk ; working conditions
    Language English
    Dates of publication 2021-05
    Size p. 1657-1670.
    Publishing place Cambridge University Press
    Document type Article
    Note NAL-AP-2-clean
    ZDB-ID 1436024-x
    ISSN 1475-2727 ; 1368-9800
    ISSN (online) 1475-2727
    ISSN 1368-9800
    DOI 10.1017/S1368980020001445
    Database NAL-Catalogue (AGRICOLA)

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  5. Article ; Online: Are dietary interventions with a behaviour change theoretical framework effective in changing dietary patterns? A systematic review.

    Timlin, Deirdre / McCormack, Jacqueline M / Kerr, Maeve / Keaver, Laura / Simpson, Ellen E A

    BMC public health

    2020  Volume 20, Issue 1, Page(s) 1857

    Abstract: Background: The term 'whole dietary pattern' can be defined as the quantity, frequency, variety and combination of different foods and drinks typically consumed and a growing body of research supports the role of whole dietary patterns in influencing ... ...

    Abstract Background: The term 'whole dietary pattern' can be defined as the quantity, frequency, variety and combination of different foods and drinks typically consumed and a growing body of research supports the role of whole dietary patterns in influencing the risk of non-communicable diseases. For example, the 'Mediterranean diet', which compared to the typical Western diet is rich in fruits and vegetables, whole grains, and oily fish, is associated with reduced risk of cardiovascular disease and cancer. Social Cognition Models provide a basis for understanding the determinants of behaviour and are made up of behavioural constructs that interventions target to change dietary behaviour. The aim of this systematic review was to provide a comprehensive assessment of the effectiveness and use of psychological theory in dietary interventions that promote a whole dietary pattern.
    Methods: We undertook a systematic review using the Preferred Reporting Items for Systematic Reviews and Meta-Analysis to synthesize quantitative research studies found in Embase, Medline, PsycInfo, CINAHL and Web of Science. The studies included were randomised and non-randomised trials published in English, involving the implementation of a whole dietary pattern using a Social Cognition Model to facilitate this. Two independent reviewers searched the articles and extracted data from the articles. The quality of the articles was evaluated using Black and Down quality checklist and Theory Coding Scheme.
    Results: Nine intervention studies met the criteria for inclusion. Data from studies reporting on individual food group scores indicated that dietary scores improved for at least one food group. Overall, studies reported a moderate application of the theory coding scheme, with poor reporting on fidelity.
    Conclusion: To our knowledge, this is the first review to investigate psychological theory driven interventions to promote whole dietary patterns. This review found mixed results for the effectiveness of using psychological theory to promote whole dietary pattern consumption. However, the studies in this review scored mostly moderate on the theory coding scheme suggesting studies are not rigorously applying theory to intervention design. Few studies reported high on treatment fidelity, therefore, translation of research interventions into practice may further impact on effectiveness of intervention. Further research is needed to identify which behaviour change theory and techniques are most salient in dietary interventions.
    MeSH term(s) Cardiovascular Diseases ; Diet, Mediterranean ; Fruit ; Humans ; Noncommunicable Diseases ; Vegetables
    Language English
    Publishing date 2020-12-03
    Publishing country England
    Document type Journal Article ; Meta-Analysis ; Systematic Review
    ZDB-ID 2041338-5
    ISSN 1471-2458 ; 1471-2458
    ISSN (online) 1471-2458
    ISSN 1471-2458
    DOI 10.1186/s12889-020-09985-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Comparison of barriers and facilitators of MIND diet uptake among adults from Northern Ireland and Italy.

    Timlin, Deirdre / Giannantoni, Barbara / McCormack, Jacqueline M / Polito, Angela / Ciarapica, Donatella / Azzini, Elena / Giles, Melanie / Simpson, Ellen E A

    BMC public health

    2021  Volume 21, Issue 1, Page(s) 265

    Abstract: Background: The aim of the study was to identify and compare components of the COM-B (capability, opportunity, motivation and behaviour) model, that influences behaviour to modify dietary patterns in 40-55-year olds living in Northern Ireland (NI) and ... ...

    Abstract Background: The aim of the study was to identify and compare components of the COM-B (capability, opportunity, motivation and behaviour) model, that influences behaviour to modify dietary patterns in 40-55-year olds living in Northern Ireland (NI) and Italy, in order to reduce the risk of cognitive decline in later life.
    Methods: This was a qualitative study examining factors influencing Mediterranean-DASH (Dietary Approaches to Stop Hypertension) Intervention for Neurodegenerative Delay (MIND) diet behaviour. This study further elaborated the COM-B components into the 14 domains of the Theoretical Domains Framework to further understand behaviour. Twenty-five Northern Irish and Italian participants were recruited onto the study, to take part in either a focus group or an interview. Participants were both male and female aged between 40 and 55 years.
    Results: Thematic analysis revealed that the main barriers to the uptake of the MIND diet were; time, work environment (opportunity), taste preference and convenience (motivation). Culture (motivation), seasonal foods and lack of family support (opportunity) to be a barrier to the Italian sample only. The main facilitators reported were; improved health, memory, planning and organisation (motivation) and access to good quality food (opportunity). Cooking skills, knowledge (capability) and heathy work lunch (opportunity) reported as a facilitator to the Italian sample only.
    Conclusions: Cross-cultural differences in relation to psychosocial barriers and facilitators were found in both samples. More barriers than facilitators towards uptake of the MIND diet were found. There is a need for interventions that increase capability, opportunity, and motivation to aid behaviour change. The findings from this study will be used to design a behaviour change intervention using the subsequent steps from the Behaviour Change Wheel.
    MeSH term(s) Adult ; Diet ; Female ; Health Promotion ; Humans ; Italy ; Male ; Middle Aged ; Motivation ; Northern Ireland
    Language English
    Publishing date 2021-02-02
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ISSN 1471-2458
    ISSN (online) 1471-2458
    DOI 10.1186/s12889-021-10307-9
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Subclinical Myocarditis After Combination Immune Checkpoint Inhibitor Therapy.

    Giblin, Gerard T / Dennehy, Colum / Featherstone, Hannah / Clarke, Rachel / Murphy, Laura / Timlin, Deirdre / O'Keane, Conor / Mulligan, Niall / Kelly, Catherine M / Joyce, Emer

    Circulation. Heart failure

    2021  Volume 14, Issue 2, Page(s) e007524

    MeSH term(s) Autoimmune Diseases/chemically induced ; Autoimmune Diseases/diagnostic imaging ; Autoimmune Diseases/drug therapy ; Autoimmune Diseases/pathology ; CD8-Positive T-Lymphocytes/pathology ; Dermatitis/etiology ; Diarrhea/chemically induced ; Echocardiography ; Female ; Glucocorticoids/therapeutic use ; Humans ; Immune Checkpoint Inhibitors/adverse effects ; Immunoglobulins, Intravenous/therapeutic use ; Immunologic Factors/therapeutic use ; Ipilimumab/adverse effects ; Lymph Nodes/pathology ; Lymphatic Metastasis ; Magnetic Resonance Imaging ; Melanoma/drug therapy ; Melanoma/secondary ; Middle Aged ; Myocarditis/chemically induced ; Myocarditis/diagnostic imaging ; Myocarditis/drug therapy ; Myocarditis/pathology ; Natriuretic Peptide, Brain/blood ; Nivolumab/adverse effects ; Skin Neoplasms/pathology ; Telemetry ; Thyroiditis/chemically induced ; Troponin I/blood
    Chemical Substances Glucocorticoids ; Immune Checkpoint Inhibitors ; Immunoglobulins, Intravenous ; Immunologic Factors ; Ipilimumab ; Troponin I ; Natriuretic Peptide, Brain (114471-18-0) ; Nivolumab (31YO63LBSN)
    Language English
    Publishing date 2021-01-22
    Publishing country United States
    Document type Case Reports ; Journal Article
    ZDB-ID 2429459-7
    ISSN 1941-3297 ; 1941-3289
    ISSN (online) 1941-3297
    ISSN 1941-3289
    DOI 10.1161/CIRCHEARTFAILURE.120.007524
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6745: Show issues Location:
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  8. Article ; Online: Incidence of single hit Bcl-2 and Bcl-6 rearrangements in DLBCL: the Irish experience.

    Dinneen, Kate / Timlin, Deirdre Mary / O'Hare, Kevin / Walker, Jan / Castriciano, Giuseppa / Connolly, Yvonne / Grant, Cliona / Bacon, Larry / Vandenberghe, Elisabeth / Dunne, Barbara / Jeffers, Michael / Flavin, Richard

    Journal of clinical pathology

    2020  Volume 73, Issue 10, Page(s) 689–690

    MeSH term(s) Biomarkers, Tumor/genetics ; Biomarkers, Tumor/metabolism ; Gene Rearrangement ; Humans ; Incidence ; Ireland/epidemiology ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Lymphoma, Large B-Cell, Diffuse/epidemiology ; Lymphoma, Large B-Cell, Diffuse/genetics ; Lymphoma, Large B-Cell, Diffuse/metabolism ; Prognosis ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Proto-Oncogene Proteins c-bcl-6/genetics ; Proto-Oncogene Proteins c-bcl-6/metabolism ; Retrospective Studies ; Up-Regulation
    Chemical Substances BCL2 protein, human ; BCL6 protein, human ; Biomarkers, Tumor ; Proto-Oncogene Proteins c-bcl-2 ; Proto-Oncogene Proteins c-bcl-6
    Keywords covid19
    Language English
    Publishing date 2020-07-17
    Publishing country England
    Document type Letter
    ZDB-ID 80261-x
    ISSN 1472-4146 ; 0021-9746
    ISSN (online) 1472-4146
    ISSN 0021-9746
    DOI 10.1136/jclinpath-2020-206725
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  9. Article: Incidence of single hit Bcl-2 and Bcl-6 rearrangements in DLBCL: the Irish experience

    Dinneen, Kate / Timlin, Deirdre Mary / O039, / Hare, Kevin / Walker, Jan / Castriciano, Giuseppa / Connolly, Yvonne / Grant, Cliona / Bacon, Larry / Vandenberghe, Elisabeth / Dunne, Barbara / Jeffers, Michael / Flavin, Richard

    J. clin. pathol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32680911
    Database COVID19

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  10. Article ; Online: FISH studies in DLBCL: correlations with cell of origin: the Irish experience.

    Timlin, Deirdre Mary / O'Hare, Kevin / Walker, Jan / Castriciano, Giusseppa / Connolly, Yvonne / Grant, Cliona / Bacon, Christopher Larry / Vandenberghe, Elisabeth / Dunne, Barbara / Jeffers, Michael / Flavin, Richard

    Journal of clinical pathology

    2018  Volume 71, Issue 10, Page(s) 947–948

    MeSH term(s) Biomarkers, Tumor/analysis ; Humans ; In Situ Hybridization, Fluorescence/methods ; Ireland ; Lymphoma, Large B-Cell, Diffuse/classification ; Lymphoma, Large B-Cell, Diffuse/diagnosis ; Lymphoma, Large B-Cell, Diffuse/genetics
    Chemical Substances Biomarkers, Tumor
    Language English
    Publishing date 2018-06-30
    Publishing country England
    Document type Letter
    ZDB-ID 80261-x
    ISSN 1472-4146 ; 0021-9746
    ISSN (online) 1472-4146
    ISSN 0021-9746
    DOI 10.1136/jclinpath-2018-205247
    Database MEDical Literature Analysis and Retrieval System OnLINE

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