Article ; Online: Design and Biochemical Characterization of Peptidic Inhibitors of the Myb/p300 Interaction.
2023 Volume 62, Issue 7, Page(s) 1321–1329
Abstract: The Myb transcription factor is involved in the proliferation of hematopoietic cells, and deregulation of its expression can lead to cancers such as leukemia. Myb interacts with various proteins, including the histone acetyltransferases p300 and CBP. Myb ...
| Abstract | The Myb transcription factor is involved in the proliferation of hematopoietic cells, and deregulation of its expression can lead to cancers such as leukemia. Myb interacts with various proteins, including the histone acetyltransferases p300 and CBP. Myb binds to a small domain of p300, the KIX domain (p300 |
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| MeSH term(s) | Peptides/pharmacology ; Protein Binding ; Proto-Oncogene Proteins c-myb/antagonists & inhibitors ; Proto-Oncogene Proteins c-myb/chemistry ; E1A-Associated p300 Protein/antagonists & inhibitors ; E1A-Associated p300 Protein/chemistry | |||||
| Chemical Substances | Peptides ; Proto-Oncogene Proteins c-myb ; E1A-Associated p300 Protein (EC 2.3.1.48) | |||||
| Language | English | |||||
| Publishing date | 2023-03-08 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 1108-3 | |||||
| ISSN | 1520-4995 ; 0006-2960 | |||||
| ISSN (online) | 1520-4995 | |||||
| ISSN | 0006-2960 | |||||
| DOI | 10.1021/acs.biochem.2c00690 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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