LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article ; Online: The Immunobiology and Treatment of Food Allergy.

    Barshow, Suzanne / Tirumalasetty, Jyothi / Sampath, Vanitha / Zhou, Xiaoying / Seastedt, Hana / Schuetz, Jackson / Nadeau, Kari

    Annual review of immunology

    2024  

    Abstract: IgE-mediated food allergy (IgE-FA) occurs due to a breakdown in immune tolerance that leads to a detrimental type 2 helper T cell ( ... ...

    Abstract IgE-mediated food allergy (IgE-FA) occurs due to a breakdown in immune tolerance that leads to a detrimental type 2 helper T cell (T
    Language English
    Publishing date 2024-02-15
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604953-9
    ISSN 1545-3278 ; 0732-0582
    ISSN (online) 1545-3278
    ISSN 0732-0582
    DOI 10.1146/annurev-immunol-090122-043501
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Se 849: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Peanut allergy: risk factors, immune mechanisms, and best practices for oral immunotherapy success.

    Tirumalasetty, Jyothi / Barshow, Suzanne / Kost, Laurie / Morales, Lu / Sharma, Reyna / Lazarte, Carlos / Nadeau, Kari C

    Expert review of clinical immunology

    2023  Volume 19, Issue 7, Page(s) 785–795

    Abstract: Introduction: Peanut oral immunotherapy (pOIT) is the only FDA-approved treatment for food allergy and its adoption amongst allergist immunologists and their patients is growing. pOIT is the subject of numerous clinical trials, however, the focus is ... ...

    Abstract Introduction: Peanut oral immunotherapy (pOIT) is the only FDA-approved treatment for food allergy and its adoption amongst allergist immunologists and their patients is growing. pOIT is the subject of numerous clinical trials, however, the focus is often on treatment efficacy, safety, and tolerability, rather than identifying patients most likely to benefit from pOIT. Here, we review existing data on the clinical and immunological outcomes of pOIT that inform best practices for pOIT candidate selection.
    Areas covered: In this review, we describe the natural history of peanut allergy, summarize immunological and clinical outcomes of pOIT at different ages, discuss the optimization of pOIT in key age groups, and finally suggest an ideal age range at which to initiate pOIT for best outcomes.
    Expert opinion: pOIT is currently underutilized by patients and allergist-immunologists. Developing guidelines for selecting appropriate patients and optimizing treatment may help to increase access to pOIT. Many aspects of pOIT need additional study to further our understanding of the optimal timing to start pOIT, with careful consideration to clinical, immunological, and quality of life outcomes.
    MeSH term(s) Humans ; Peanut Hypersensitivity ; Quality of Life ; Desensitization, Immunologic/adverse effects ; Allergens/therapeutic use ; Administration, Oral ; Arachis ; Immunotherapy ; Immunologic Factors/therapeutic use
    Chemical Substances Allergens ; Immunologic Factors
    Language English
    Publishing date 2023-05-05
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 2274260-8
    ISSN 1744-8409 ; 1744-666X
    ISSN (online) 1744-8409
    ISSN 1744-666X
    DOI 10.1080/1744666X.2023.2209318
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 6661: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article: Asthma, surgery, and general anesthesia: a review.

    Tirumalasetty, Jyothi / Grammer, Leslie C

    The Journal of asthma : official journal of the Association for the Care of Asthma

    2006  Volume 43, Issue 4, Page(s) 251–254

    Abstract: Over 20 million Americans are affected with asthma. Many will require some type of surgical procedure during which their asthma management should be optimized. Preoperative assessment of asthma should include a specialized history and physical as well as ...

    Abstract Over 20 million Americans are affected with asthma. Many will require some type of surgical procedure during which their asthma management should be optimized. Preoperative assessment of asthma should include a specialized history and physical as well as pulmonary function testing. In many asthmatic patients, treatment with systemic corticosteroids and bronchodilators is indicated to prevent the inflammation and bronchoconstriction associated with endotracheal intubation. The use of corticosteroids has not been shown to adversely affect wound healing or increase the rate of infections postoperatively. Preoperative systemic corticosteroids may be used safely in the majority of patients to decrease asthma-related morbidity.
    MeSH term(s) Adrenal Cortex Hormones/administration & dosage ; Anesthesia, General/adverse effects ; Anesthesia, General/methods ; Asthma/drug therapy ; Asthma/prevention & control ; Dose-Response Relationship, Drug ; Drug Administration Schedule ; Female ; Follow-Up Studies ; Humans ; Male ; Monitoring, Intraoperative/methods ; Postoperative Care/methods ; Postoperative Complications/etiology ; Postoperative Complications/prevention & control ; Preoperative Care/methods ; Risk Assessment ; Surgical Procedures, Operative/adverse effects ; Surgical Procedures, Operative/methods ; Treatment Outcome
    Chemical Substances Adrenal Cortex Hormones
    Language English
    Publishing date 2006-05
    Publishing country England
    Document type Comparative Study ; Journal Article ; Review
    ZDB-ID 603816-5
    ISSN 0277-0903
    ISSN 0277-0903
    DOI 10.1080/02770900600643162
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 18: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article ; Online: The role of biologics in pediatric food allergy and eosinophilic gastrointestinal disorders.

    Sindher, Sayantani B / Barshow, Suzanne / Tirumalasetty, Jyothi / Arasi, Stefania / Atkins, Dan / Bauer, Maureen / Bégin, Philippe / Collins, Margaret H / Deschildre, Antoine / Doyle, Alfred D / Fiocchi, Alessandro / Furuta, Glenn T / Garcia-Lloret, Maria / Mennini, Maurizio / Rothenberg, Marc E / Spergel, Jonathan M / Wang, Julie / Wood, Robert A / Wright, Benjamin L /
    Zuberbier, Torsten / Chin, Andrew R / Long, Andrew / Nadeau, Kari C / Chinthrajah, R Sharon

    The Journal of allergy and clinical immunology

    2022  Volume 151, Issue 3, Page(s) 595–606

    Abstract: Continuing insight into the molecular mechanisms of atopic disorders has enabled the development of biologics to precisely target these diseases. Food allergy (FA) and eosinophilic gastrointestinal disorders (EGIDs) are driven by similar inflammatory ... ...

    Abstract Continuing insight into the molecular mechanisms of atopic disorders has enabled the development of biologics to precisely target these diseases. Food allergy (FA) and eosinophilic gastrointestinal disorders (EGIDs) are driven by similar inflammatory molecular mechanisms and exist along the same atopic disease spectrum. Therefore, many of the same biologics are being investigated to target key drivers of mechanisms shared across the disease states. The enormous potential of biologics for the treatment of FA and EGIDs is highlighted by the significant increases in the number of ongoing clinical trials (more than 30) evaluating their use in these disease states, as well as by the recent US Food and Drug Administration approval of dupilumab for the treatment of eosinophilic esophagitis. Here we discuss past and current research into the use of biologics in FA and EGIDs and their potential role in improving treatment options in the future, with the need to have biologics widely clinically available.
    MeSH term(s) United States ; Humans ; Child ; Biological Products ; Food Hypersensitivity ; Enteritis ; Eosinophilic Esophagitis
    Chemical Substances Biological Products
    Language English
    Publishing date 2022-12-14
    Publishing country United States
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't ; Research Support, N.I.H., Extramural
    ZDB-ID 121011-7
    ISSN 1097-6825 ; 1085-8725 ; 0091-6749
    ISSN (online) 1097-6825 ; 1085-8725
    ISSN 0091-6749
    DOI 10.1016/j.jaci.2023.01.007
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.92: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top