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  1. Article ; Online: Stabilization and Binding of [V

    Ferraro, Giarita / Tito, Gabriella / Sciortino, Giuseppe / Garribba, Eugenio / Merlino, Antonello

    Angewandte Chemie (International ed. in English)

    2023  Volume 62, Issue 50, Page(s) e202310655

    Abstract: High-resolution crystal structures of lysozyme in the presence of the potential drug ... ...

    Abstract High-resolution crystal structures of lysozyme in the presence of the potential drug V
    MeSH term(s) Muramidase/chemistry ; Oxidation-Reduction ; Proteins ; Vanadium/chemistry ; Ligands
    Chemical Substances Muramidase (EC 3.2.1.17) ; Proteins ; Vanadium (00J9J9XKDE) ; Ligands
    Language English
    Publishing date 2023-10-13
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202310655
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: On the mechanism of action of arsenoplatins: arsenoplatin-1 binding to a B-DNA dodecamer.

    Troisi, Romualdo / Tito, Gabriella / Ferraro, Giarita / Sica, Filomena / Massai, Lara / Geri, Andrea / Cirri, Damiano / Messori, Luigi / Merlino, Antonello

    Dalton transactions (Cambridge, England : 2003)

    2024  Volume 53, Issue 8, Page(s) 3476–3483

    Abstract: The reaction of Pt-based anticancer agents with arsenic trioxide affords robust complexes known as arsenoplatins. The prototype of this family of anticancer compounds is arsenoplatin-1 (AP-1) that contains an As(OH) ...

    Abstract The reaction of Pt-based anticancer agents with arsenic trioxide affords robust complexes known as arsenoplatins. The prototype of this family of anticancer compounds is arsenoplatin-1 (AP-1) that contains an As(OH)
    MeSH term(s) Cisplatin/chemistry ; Arsenic Trioxide/analogs & derivatives ; DNA, B-Form ; Transcription Factor AP-1/metabolism ; Antineoplastic Agents/chemistry ; DNA/chemistry
    Chemical Substances transplatin (14913-33-8) ; arsenoplatin-1 ; Cisplatin (Q20Q21Q62J) ; Arsenic Trioxide (S7V92P67HO) ; DNA, B-Form ; Transcription Factor AP-1 ; Antineoplastic Agents ; DNA (9007-49-2)
    Language English
    Publishing date 2024-02-20
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt04302a
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Dirhodium tetraacetate binding to a B-DNA double helical dodecamer probed by X-ray crystallography and mass spectrometry.

    Tito, Gabriella / Troisi, Romualdo / Ferraro, Giarita / Geri, Andrea / Massai, Lara / Messori, Luigi / Sica, Filomena / Merlino, Antonello

    Dalton transactions (Cambridge, England : 2003)

    2023  Volume 52, Issue 21, Page(s) 6992–6996

    Abstract: The reaction of the cytotoxic compound dirhodium tetraacetate with a B-DNA double helical dodecamer was studied by X-ray crystallography and mass spectrometry. The structure of the dirhodium/DNA adduct reveals a dimetallic center binding to an ... ...

    Abstract The reaction of the cytotoxic compound dirhodium tetraacetate with a B-DNA double helical dodecamer was studied by X-ray crystallography and mass spectrometry. The structure of the dirhodium/DNA adduct reveals a dimetallic center binding to an adenine
    MeSH term(s) Crystallography, X-Ray ; DNA, B-Form ; DNA/chemistry ; Mass Spectrometry
    Chemical Substances dirhodium tetraacetate (NK3058Z56X) ; DNA, B-Form ; DNA (9007-49-2)
    Language English
    Publishing date 2023-05-30
    Publishing country England
    Document type Journal Article
    ZDB-ID 1472887-4
    ISSN 1477-9234 ; 1364-5447 ; 0300-9246 ; 1477-9226
    ISSN (online) 1477-9234 ; 1364-5447
    ISSN 0300-9246 ; 1477-9226
    DOI 10.1039/d3dt00320e
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Impact of Hydrophobic Chains in Five-Coordinate Glucoconjugate Pt(II) Anticancer Agents.

    Annunziata, Alfonso / Imbimbo, Paola / Cucciolito, Maria Elena / Ferraro, Giarita / Langellotti, Vincenzo / Marano, Alessandra / Melchiorre, Massimo / Tito, Gabriella / Trifuoggi, Marco / Monti, Daria Maria / Merlino, Antonello / Ruffo, Francesco

    International journal of molecular sciences

    2023  Volume 24, Issue 3

    Abstract: This study describes new platinum(II) cationic five-coordinate complexes ( ...

    Abstract This study describes new platinum(II) cationic five-coordinate complexes (
    MeSH term(s) Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Crystallography, X-Ray ; Dimethyl Sulfoxide ; DNA ; Hydrophobic and Hydrophilic Interactions ; Muramidase ; Platinum Compounds/chemistry ; Platinum Compounds/pharmacology
    Chemical Substances Antineoplastic Agents ; carbene (2465-56-7) ; Dimethyl Sulfoxide (YOW8V9698H) ; DNA (9007-49-2) ; ethylene (91GW059KN7) ; Muramidase (EC 3.2.1.17) ; Platinum Compounds
    Language English
    Publishing date 2023-01-25
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2019364-6
    ISSN 1422-0067 ; 1422-0067 ; 1661-6596
    ISSN (online) 1422-0067
    ISSN 1422-0067 ; 1661-6596
    DOI 10.3390/ijms24032369
    Database MEDical Literature Analysis and Retrieval System OnLINE

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