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  1. Article ; Online: Beware of air.

    van Rijssel, Nadia Nk / Savelkoul, Claudia C / Tjan, David H T

    BMJ case reports

    2018  Volume 2018

    MeSH term(s) Abdominal Pain/etiology ; Aged ; Air ; Back Pain/etiology ; Chest Pain/etiology ; Diagnosis, Differential ; Diverticulitis/complications ; Diverticulitis/diagnosis ; Diverticulitis/diagnostic imaging ; Female ; Humans ; Male ; Megacolon, Toxic/complications ; Megacolon, Toxic/diagnosis ; Megacolon, Toxic/diagnostic imaging ; Middle Aged ; Pneumoperitoneum/complications ; Pneumoperitoneum/diagnosis ; Pneumoperitoneum/diagnostic imaging ; Retropharyngeal Abscess/complications ; Retropharyngeal Abscess/diagnosis ; Retropharyngeal Abscess/diagnostic imaging ; Tomography, X-Ray Computed
    Language English
    Publishing date 2018-01-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2017-223081
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Colopleural fistula after hiatal hernia repair.

    Peters van Ton, Annemieke M / Diederik, Arjen L / Tjan, David H

    BMJ case reports

    2016  Volume 2016

    MeSH term(s) Aged ; Colonic Diseases/diagnostic imaging ; Colonic Diseases/etiology ; Hernia, Hiatal/surgery ; Herniorrhaphy/adverse effects ; Humans ; Intestinal Fistula/diagnostic imaging ; Intestinal Fistula/etiology ; Male ; Pleural Diseases/diagnostic imaging ; Pleural Diseases/etiology ; Postoperative Complications/diagnostic imaging ; Postoperative Complications/etiology ; Respiratory Tract Fistula/diagnostic imaging ; Respiratory Tract Fistula/etiology ; Tomography, X-Ray Computed
    Language English
    Publishing date 2016-08-17
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2016-216814
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Quick recognition of a threatened airway in a patient with a swelling in the neck.

    van Ton, Annemieke M Peters / Volders, Jose / Tjan, David H

    BMJ case reports

    2014  Volume 2014

    MeSH term(s) Aged, 80 and over ; Dyspnea/etiology ; Goiter, Nodular/complications ; Humans ; Hyperthyroidism/complications ; Male ; Respiratory Sounds/etiology ; Tracheal Diseases/etiology
    Language English
    Publishing date 2014-09-29
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2014-207166
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Catastrophic complication of an electromagnetic placed postpyloric feeding tube.

    Veltcamp Helbach, Marloes / Savelkoul, Claudia / Festen-Spanjer, Barbara / Tjan, David H

    BMJ case reports

    2016  Volume 2016

    MeSH term(s) Aged, 80 and over ; Colectomy ; Enteral Nutrition/adverse effects ; Female ; Humans ; Intubation, Gastrointestinal/adverse effects ; Intubation, Gastrointestinal/instrumentation ; Magnets/adverse effects ; Postoperative Care/adverse effects ; Postoperative Care/instrumentation ; Respiratory Insufficiency/etiology
    Language English
    Publishing date 2016-09-06
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2016-216738
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: A Comatose Patient with a Bluish Tongue.

    van Hulst, Annelienke M / Lammers, Hendrick J W / Koekkoek, W A C Kristine / Smulders, Charlotte A / Tjan, David H T

    Clinical chemistry

    2018  Volume 64, Issue 8, Page(s) 1143–1145

    MeSH term(s) Adult ; Clonazepam/blood ; Clonazepam/toxicity ; Color ; Coma/pathology ; GABA Modulators/blood ; GABA Modulators/toxicity ; Humans ; Male ; Tongue/pathology
    Chemical Substances GABA Modulators ; Clonazepam (5PE9FDE8GB)
    Language English
    Publishing date 2018-07-25
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 80102-1
    ISSN 1530-8561 ; 0009-9147
    ISSN (online) 1530-8561
    ISSN 0009-9147
    DOI 10.1373/clinchem.2017.278200
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Sudden cardiac arrest as a presentation of Brugada syndrome unmasked by thyroid storm.

    Korte, Anna K M / Derde, Lennie / van Wijk, Jeroen / Tjan, David H

    BMJ case reports

    2015  Volume 2015

    Abstract: An 18-year-old man suffered a sudden cardiac arrest with ventricular fibrillation and was successfully resuscitated. He had neither a medical nor family history of cardiac disease/sudden death, but was known to have Graves' disease, for which he was ... ...

    Abstract An 18-year-old man suffered a sudden cardiac arrest with ventricular fibrillation and was successfully resuscitated. He had neither a medical nor family history of cardiac disease/sudden death, but was known to have Graves' disease, for which he was treated with radioactive iodine. Recently, block-and-replacement therapy had been discontinued to evaluate thyroid functioning. On admission, thyroid hormone levels were markedly elevated, suggesting thyroid storm due to residual Graves' disease. The patient was treated with propylthiouracil, hydrocortisone and Lugol solution. ECG showed repolarisation patterns suggestive of an underlying type 1 Brugada syndrome (BS). These findings were confirmed by an additional ajmaline test. An implantable cardioverter defibrillator was implanted to prevent future arrhythmias. The patient underwent total thyroidectomy 9 months later and recovered completely. To the best of our knowledge, this is the first reported case of a sudden cardiac arrest as a presentation of BS unmasked by thyroid storm.
    MeSH term(s) Adolescent ; Brugada Syndrome/complications ; Brugada Syndrome/diagnosis ; Brugada Syndrome/physiopathology ; Death, Sudden, Cardiac/etiology ; Electrocardiography ; Graves Disease/complications ; Humans ; Male ; Thyroid Crisis/etiology
    Language English
    Publishing date 2015-12-30
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2015-212351
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: An unusual neurological consequence of massive wasp stings.

    Volders, José / Smits, Marcel / Folkersma, Gerbrich / Tjan, David H

    BMJ case reports

    2012  Volume 2012

    Abstract: Although rare, central and peripheral neurological manifestations after single or multiple wasp stings have been reported. The authors describe a 45-year-old man who developed periods of sudden loss of consciousness with a Glasgow Coma Scale of 6 after ... ...

    Abstract Although rare, central and peripheral neurological manifestations after single or multiple wasp stings have been reported. The authors describe a 45-year-old man who developed periods of sudden loss of consciousness with a Glasgow Coma Scale of 6 after being stung by fifty wasps. These periods were seen directly after being stung and were continuing months later. Different mechanisms and pathophysiological findings of neurological sequela reported after wasp stings are being reviewed.
    MeSH term(s) Animals ; Glasgow Coma Scale ; Humans ; Insect Bites and Stings/complications ; Insect Bites and Stings/drug therapy ; Male ; Middle Aged ; Unconsciousness/etiology ; Unconsciousness/therapy ; Wasps
    Language English
    Publishing date 2012-06-28
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr.01.2012.5555
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Milde therapeutische hypothermie na reanimatie. Ervaringen en resultaten van de eerste 2 jaar na implementatie.

    Haas, Lenneke E M / Tjan, David H T / van Zanten, Arthur R H

    Nederlands tijdschrift voor geneeskunde

    2009  Volume 153, Page(s) B315

    Abstract: Objective: To describe the results of mild therapeutic hypothermia (MTH) following resuscitation in the 'Gelderse Vallei' hospital, Ede, the Netherlands.: Design: Descriptive, retrospective.: Method: Patient data was collected from patients who ... ...

    Title translation Mild therapeutic hypothermia following resuscitation; experience and results in the first two years after introduction.
    Abstract Objective: To describe the results of mild therapeutic hypothermia (MTH) following resuscitation in the 'Gelderse Vallei' hospital, Ede, the Netherlands.
    Design: Descriptive, retrospective.
    Method: Patient data was collected from patients who had undergone MTH during the first two years following introduction of this treatment in the intensive care department of the 'Gelderse Vallei' hospital, Ede. Information used in the description included patient characteristics, heart arrest type (ventricular fibrillation or other arrhythmias), place of onset (in hospital or elsewhere), resuscitation data, side effects of the treatment, mortality and neurological outcome.
    Results: 67 patients were treated with MTH in the period April 2005 to July 2007. The hospital mortality rate within this group was 81%. The mortality rate in the subgroup presenting with ventricular fibrillation as initial arrhythmia was 76%, compared with 89% in the subgroup with other arrhythmias. The mortality rate of patients who were resuscitated outside the hospital was comparable with that for patients resuscitated in hospital (80% versus 83%). Patients who could be discharged from hospital had a good neurological outcome (average Cerebral Performance Category score 1.9; 95%-CI: 1.6-2.2). The most important complications during MTH were electrolyte imbalances and ventilator associated pneumonia.
    Conclusion: The introduction of MTH in the intensive care department of the "Gelderse Vallei" has taken place without major problems. Although the mortality rate following cardiopulmonary resuscitation was relatively high, the neurological outcome in those patients who were discharged from hospital alive was good.
    MeSH term(s) APACHE ; Aged ; Cardiopulmonary Resuscitation/adverse effects ; Cardiopulmonary Resuscitation/methods ; Female ; Heart Arrest/mortality ; Heart Arrest/therapy ; Humans ; Hypothermia, Induced ; Male ; Netherlands ; Pneumonia, Ventilator-Associated/epidemiology ; Pneumonia, Ventilator-Associated/etiology ; Retrospective Studies ; Survival Analysis ; Water-Electrolyte Imbalance/epidemiology ; Water-Electrolyte Imbalance/etiology
    Language Dutch
    Publishing date 2009
    Publishing country Netherlands
    Document type English Abstract ; Journal Article
    ZDB-ID 82073-8
    ISSN 1876-8784 ; 0028-2162
    ISSN (online) 1876-8784
    ISSN 0028-2162
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Markers of immune-mediated inflammation in the brains of young adults and adolescents with type 1 diabetes and fatal diabetic ketoacidosis. Is there a difference?

    Hoffman, William H / Artlett, Carol M / Boodhoo, Dallas / Gilliland, Mary G F / Ortiz, Luis / Mulder, Dries / Tjan, David H T / Martin, Alvaro / Tatomir, Alexandru / Rus, Horea

    Experimental and molecular pathology

    2017  Volume 102, Issue 3, Page(s) 505–514

    Abstract: Due to the limited data on diabetic ketoacidosis and brain edema (DKA/BE) in children/adolescents and the lack of recent data on adults with type 1 diabetes (T1D), we addressed the question of whether neuroinflammation was present in the fatal DKA of ... ...

    Abstract Due to the limited data on diabetic ketoacidosis and brain edema (DKA/BE) in children/adolescents and the lack of recent data on adults with type 1 diabetes (T1D), we addressed the question of whether neuroinflammation was present in the fatal DKA of adults. We performed immunohistochemistry (IHC) studies on the brains of two young adults with T1D and fatal DKA and compared them with two teenagers with poorly controlled diabetes and fatal DKA. C5b-9, the membrane attack complex (MAC) had significantly greater deposits in the grey and white matter of the teenagers than the young adults (p=0.03). CD59, a MAC assembly inhibitory protein was absent, possibly suppressed by the hyperglycemia in the teenagers but was expressed in the young adults despite comparable average levels of hyperglycemia. The receptor for advanced glycation end products (RAGE) had an average expression in the young adults significantly greater than in the teenagers (p=0.02). The autophagy marker Light Chain 3 (LC3) A/B was the predominant form of programmed cell death (PCD) in the teenage brains. The young adults had high expressions of both LC3A/B and TUNEL, an apoptotic cell marker for DNA fragmentation. BE was present in the newly diagnosed young adult with hyperglycemic hyperosmolar DKA and also in the two teenagers. Our data indicate that significant differences in neuroinflammatory components, initiated by the dysregulation of DKA and interrelated metabolic and immunologic milieu, are likely present in the brains of fatal DKA of teenagers when compared with young adults.
    MeSH term(s) Adolescent ; Adult ; Autophagy ; Biomarkers/metabolism ; Brain/physiopathology ; Brain Edema/diagnosis ; Brain Edema/etiology ; Brain Edema/genetics ; CD59 Antigens/genetics ; CD59 Antigens/metabolism ; DNA Fragmentation ; Diabetes Mellitus, Type 1/complications ; Diabetes Mellitus, Type 1/genetics ; Diabetic Ketoacidosis/complications ; Diabetic Ketoacidosis/genetics ; Gene Expression Regulation ; Humans ; Immunohistochemistry ; In Situ Nick-End Labeling ; Inflammation Mediators/metabolism ; Microtubule-Associated Proteins/genetics ; Microtubule-Associated Proteins/metabolism ; Neurogenic Inflammation/etiology ; Neurogenic Inflammation/genetics ; Young Adult
    Chemical Substances Biomarkers ; CD59 Antigens ; Inflammation Mediators ; MAP1LC3A protein, human ; Microtubule-Associated Proteins ; CD59 protein, human (101754-01-2)
    Language English
    Publishing date 2017-05-19
    Publishing country Netherlands
    Document type Case Reports ; Journal Article
    ZDB-ID 207655-x
    ISSN 1096-0945 ; 0014-4800
    ISSN (online) 1096-0945
    ISSN 0014-4800
    DOI 10.1016/j.yexmp.2017.05.013
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Preventing nosocomial sinusitis in the ICU: Comment on article by Pneumatikos et al.

    van Zanten, Arthur R H / Tjan, David H T / Polderman, Kees H

    Intensive care medicine

    2006  Volume 32, Issue 9, Page(s) 1451; author reply 1452–3

    MeSH term(s) Cross Infection/diagnostic imaging ; Cross Infection/prevention & control ; Humans ; Intensive Care Units ; Intubation, Gastrointestinal ; Risk Factors ; Sinusitis/diagnostic imaging ; Sinusitis/prevention & control ; Tomography, X-Ray Computed
    Language English
    Publishing date 2006-09
    Publishing country United States
    Document type Letter ; Comment
    ZDB-ID 80387-x
    ISSN 1432-1238 ; 0342-4642 ; 0340-0964 ; 0935-1701
    ISSN (online) 1432-1238
    ISSN 0342-4642 ; 0340-0964 ; 0935-1701
    DOI 10.1007/s00134-006-0275-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

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