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  1. Article ; Online: Social deprivation independently impacts clinical outcomes in patients with chronic lymphocytic leukemia.

    Fegan, Gregory / Tod, Daniel / Downing, Abigail / Elmusharaf, Nagah / Pepper, Christopher / Fegan, Christopher

    Haematologica

    2024  Volume 109, Issue 5, Page(s) 1566–1569

    MeSH term(s) Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/mortality ; Leukemia, Lymphocytic, Chronic, B-Cell/therapy ; Male ; Female ; Aged ; Middle Aged ; Prognosis ; Treatment Outcome
    Language English
    Publishing date 2024-05-01
    Publishing country Italy
    Document type Letter ; Research Support, Non-U.S. Gov't ; Journal Article
    ZDB-ID 2333-4
    ISSN 1592-8721 ; 0017-6567 ; 0390-6078
    ISSN (online) 1592-8721
    ISSN 0017-6567 ; 0390-6078
    DOI 10.3324/haematol.2023.283527
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Uh III Zs.76: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article: Group-based positive psychotherapy for people living with acquired brain injury: a protocol for a feasibility study.

    Fisher, Zoe / Field, Susannah / Fitzsimmons, Deb / Hutchings, Hayley / Carter, Kym / Tod, Daniel / Gracey, Fergus / Knight, Alec / Kemp, Andrew H

    Pilot and feasibility studies

    2024  Volume 10, Issue 1, Page(s) 38

    Abstract: Background: Acquired brain injury (ABI) and other chronic conditions are placing unprecedented pressure on healthcare systems. In the UK, 1.3 million people live with the effects of brain injury, costing the UK economy approximately £15 billion per year. ...

    Abstract Background: Acquired brain injury (ABI) and other chronic conditions are placing unprecedented pressure on healthcare systems. In the UK, 1.3 million people live with the effects of brain injury, costing the UK economy approximately £15 billion per year. As a result, there is an urgent need to adapt existing healthcare delivery to meet increasing current and future demands. A focus on wellbeing may provide an innovative opportunity to reduce the pressure on healthcare services while also supporting patients to live more meaningful lives. The overarching aims of the study are as follows: (1) evaluate the feasibility of conducting a positive psychotherapy intervention for individuals with ABI and (2) ascertain under what conditions such an intervention would merit a fully powered randomised controlled trial (RCT) compared to a standard control group (TAU).
    Methods and analysis: A randomised, two-arm feasibility trial involving allocation of patients to either a treatment group (positive psychotherapy) or control group (treatment as usual) group, according to a 1:1 ratio. A total of 60 participants at three sites will be recruited including 20 participants at each site. Assessments will be conducted at baseline, on completion of the 8-week intervention and 3 months following completion. These will include a range of questionnaire-based measures, psychophysiology and qualitative outcomes focusing on feasibility outcomes and participant experience. This study has been approved by the Wales Research Ethics Committee (IRAS project ID: 271,251, REC reference: 19/WA/0336).
    Discussion: This study will be the first to examine the feasibility of an innovative, holistic positive psychotherapy intervention for people living with ABI, focused on individual, collective and planetary wellbeing, and will enable us to determine whether to proceed to a full randomised controlled trial.
    Trial registration: ISRCTN12690685 , registered 11th November 2020.
    Language English
    Publishing date 2024-02-21
    Publishing country England
    Document type Journal Article
    ZDB-ID 2809935-7
    ISSN 2055-5784
    ISSN 2055-5784
    DOI 10.1186/s40814-024-01459-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Are Welsh primary schools Sunproofed? Results of a national survey Part 1: Scoping the landscape of sun safety policies in Wales.

    Peconi, Julie / Lanyon, Kirsty / Tod, Daniel / Driscoll, Timothy / Prathap, Swetha / Watkins, Alan / Abbott, Rachel A

    Clinical and experimental dermatology

    2024  

    Abstract: Background: Schools with formal sun safety polices generally show better sun safety practices than schools without.: Objectives: Understand the extent to which Welsh primary schools have sun safety policies; identify key characteristics of policies; ... ...

    Abstract Background: Schools with formal sun safety polices generally show better sun safety practices than schools without.
    Objectives: Understand the extent to which Welsh primary schools have sun safety policies; identify key characteristics of policies; assess whether policy adoption varies by school characteristics; and consider what support schools need to develop sun safety policies.
    Methods: An online multiple-choice survey distributed to all 1241 primary schools in Wales asking about sun safety.
    Results: In total, 471/1241 (38.0%) schools responded. Of these, 183 (39.0%) reported having a formal sun safety policy. Welsh medium schools (p=0.036) and schools in North Wales (p=0.008) were more likely to report having a policy. Schools with a higher percentage of pupils receiving free school meals (p=0.046) and with lower attendance rates (p=0.008) were less likely to report having a sun safety policy.Primary reasons for schools not having a policy included: 'unaware of the need' (34.6%); needing assistance with policy development (30.3%) and 'not got around to it' (26.8%).
    Conclusion: With less than half of schools reporting a sun safety policy and variation in the presence/absence of a policy by school characteristics, our survey shows inconsistency in formal sun safety provision in Welsh schools. Findings also suggest that schools are unaware of the importance of sun safety and need support to develop and implement policies. This snapshot of the current situation in primary schools in Wales provides a basis upon which the comprehensiveness, effectiveness, and implementation of sun safety policies can be further evaluated.
    Language English
    Publishing date 2024-01-04
    Publishing country England
    Document type Journal Article
    ZDB-ID 195504-4
    ISSN 1365-2230 ; 0307-6938
    ISSN (online) 1365-2230
    ISSN 0307-6938
    DOI 10.1093/ced/llad458
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1278: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: Can we collect health-related quality of life information from anticoagulated atrial fibrillation participants who have recently experienced a bleed? An observational feasibility study in primary and secondary care in Wales and through a UK online forum.

    Hutchings, Hayley Anne / Lanyon, Kirsty J / Holland, Gail / Alikhan, Raza / Jenkins, Rhys / Laing, Hamish / Hughes, Arfon / Lobban, Trudie / Pollock, Kevin / Tod, Daniel / Lister, Steven

    BMJ open

    2023  Volume 13, Issue 10, Page(s) e075335

    Abstract: Objective: To evaluate the feasibility of recruiting participants diagnosed with atrial fibrillation (AF) taking oral anticoagulation therapies (OATs) and recently experiencing a bleed to collect health-related quality of life (HRQoL) information.: ... ...

    Abstract Objective: To evaluate the feasibility of recruiting participants diagnosed with atrial fibrillation (AF) taking oral anticoagulation therapies (OATs) and recently experiencing a bleed to collect health-related quality of life (HRQoL) information.
    Design: Observational feasibility study. The study aimed to determine the feasibility of recruiting participants with minor and major bleeds, the most appropriate route for recruitment and the appropriateness of the patient-reported outcome measures (PROMs) selected for collecting HRQoL information in AF patients, and the preferred format of the surveys.
    Setting: Primary care, secondary care and via an online patient forum.
    Participants: The study population was adult patients (≥18) with AF taking OATs who had experienced a recent major or minor bleed within the last 4 weeks.
    Primary and secondary outcome measures: Primary outcomes
    Results: We received initial expressions of interest from 103 participants. We subsequently recruited 32 participants to the study-14 from primary care and 18 through the AF forum. No participants were recruited through secondary care. Despite 32 participants consenting, only 26 initial surveys were completed. We received follow-up surveys from 11 participants (8 primary care and 3 AF forum). COVID-19 had a major impact on the study.
    Conclusions: Primary care was the most successful route for recruitment. Most participants recruited to the study experienced a minor bleed. Further ways to recruit in secondary care should be explored, especially to capture more serious bleeds.
    Trial registration number: The study is registered in the Clinicaltrials.gov database, NCT04921176.
    MeSH term(s) Adult ; Humans ; Atrial Fibrillation/drug therapy ; Atrial Fibrillation/diagnosis ; Secondary Care ; Feasibility Studies ; Quality of Life ; Wales ; COVID-19 ; Hemorrhage/diagnosis ; Anticoagulants/therapeutic use
    Chemical Substances Anticoagulants
    Language English
    Publishing date 2023-10-06
    Publishing country England
    Document type Observational Study ; Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2023-075335
    Database MEDical Literature Analysis and Retrieval System OnLINE

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