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  1. Article ; Online: Hematocrit: The Neglected Variable of Extracorporeal CO

    Vivona, Luigi / Battistin, Michele / Carlesso, Eleonora / Florio, Gaetano / Todaro, Serena / Colombo, Sebastiano M / Zadek, Francesco / Grasselli, Giacomo / Zanella, Alberto / Langer, Thomas

    American journal of respiratory and critical care medicine

    2023  Volume 209, Issue 5, Page(s) 595–598

    MeSH term(s) Humans ; Hematocrit ; Carbon Dioxide
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2023-11-30
    Publishing country United States
    Document type Letter
    ZDB-ID 1180953-x
    ISSN 1535-4970 ; 0003-0805 ; 1073-449X
    ISSN (online) 1535-4970
    ISSN 0003-0805 ; 1073-449X
    DOI 10.1164/rccm.202309-1697LE
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Optimizing barium promoter for nickel catalyst supported on yttria‐stabilized zirconia in dry reforming of methane

    Ahmed Sadeq Al‐Fatesh / Ahmed Aidid Ibrahim / Ahmed I. Osman / Fahad Albaqi / Rasheed Arasheed / Frusteri Francesco / Todaro Serena / Khalid Anojaidi / Mahmud Sofiu Lanre / Ahmed Elhag Abasaeed / Anis Hamza Fakeeha / Abdulaziz Bentalib / Abdulaziz Bagabas

    Energy Science & Engineering, Vol 11, Iss 6, Pp 2066-

    2023  Volume 2080

    Abstract: Abstract Barium doping effect on the activity and stability of nickel‐based catalysts, supported on yttria‐stabilized zirconia (Ni‐YZr), was investigated in dry reforming of methane. Catalysts were characterized by several techniques (nitrogen sorption, ... ...

    Abstract Abstract Barium doping effect on the activity and stability of nickel‐based catalysts, supported on yttria‐stabilized zirconia (Ni‐YZr), was investigated in dry reforming of methane. Catalysts were characterized by several techniques (nitrogen sorption, X‐ray diffraction [XRD], scanning electron microscopy with energy dispersive X‐ray, transmission electron microscopy [TEM], thermogravimetric analysis [TGA], temperature programmed oxidation, CO2‐TPD, H2‐TPR) and were tested in a fixed‐bed reactor at 800°C and 42,000 mL/h gcat. Barium played a crucial role in enhancing catalyst reducibility and CO2 adsorption at high temperatures, as indicated by the activity and stability of the Ni‐YZr catalyst. The addition of 4.0 wt% of barium appeared to be the optimal loading, allowing for CH4 conversion of 82%, which remained constant for 7 h of reaction, compared with 72% of barium‐unpromoted Ni‐YZr at 800°C. TEM images of the spent catalysts revealed the formation of multiwalled carbon nanotubes on all samples. The TGA analysis showed, however, that an increase in baria loading significantly reduced the coke formation amount, indicating the inhibition of coke formation and the enhancement of the catalytic activity. Such improvement in activity and stability was attributed to the incorporation of barium into YZr support, as revealed by XRD analysis, which inhibited the sintering of the catalysts support.
    Keywords barium promoter ; environmental catalysis ; methane dry reforming ; nickel catalyst ; yttria‐stabilized zirconia support ; Technology ; T ; Science ; Q
    Subject code 660
    Language English
    Publishing date 2023-06-01T00:00:00Z
    Publisher Wiley
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  3. Article ; Online: Portal hypertension-like pattern in coronavirus disease 2019 acute respiratory distress syndrome.

    Dondossola, Daniele / Lonati, Caterina / Pini, Alessia / Bignamini, Daniela / Zanella, Alberto / Lombardi, Rosa / Scaravilli, Vittorio / La Mura, Vincenzo / Forzenigo, Laura / Biondetti, Pierpaolo / Grasselli, Giacomo / Fracanzani, Anna / Paleari, Chiara / Cespiati, Annalisa / Todaro, Serena / Cattaneo, Emanuele / Di Feliciantonio, Marianna / Sigon, Giordano / Valsecchi, Carlo /
    Guzzardella, Amedeo / Battistin, Michele / Iuculano, Federica

    Journal of critical care

    2024  Volume 82, Page(s) 154759

    Abstract: Objectives: Although respiratory failure is the most common feature in coronavirus disease 2019 (COVID-19), abdominal organ involvement is likewise frequently observed. To investigate visceral and thoracic circulation and abdominal organ damage in COVID- ...

    Abstract Objectives: Although respiratory failure is the most common feature in coronavirus disease 2019 (COVID-19), abdominal organ involvement is likewise frequently observed. To investigate visceral and thoracic circulation and abdominal organ damage in COVID-19 patients.
    Materials and methods: A monocentric observational study was carried on. In COVID-19 patients affected by acute respiratory distress syndrome (ARDS) (n = 31) or mild pneumonia (n = 60) thoracoabdominal circulation was evaluated using Doppler-ultrasound and computed tomography. The study also included non-COVID-19 patients affected by ARDS (n = 10) or portal hypertension (n = 10) for comparison of the main circulatory changes.
    Results: Patients affected by COVID-19 ARDS showed hyperdynamic visceral flow and increased portal velocity, hepatic artery resistance-index, and spleen diameter relative to those with mild-pneumonia (p = 0.001). Splanchnic circulatory parameters significantly correlated with the main respiratory indexes (p < 0.001) and pulmonary artery diameter (p = 0.02). The chest and abdominal vascular remodeling pattern of COVID-19 ARDS patients resembled the picture observed in the PH group, while differed from that of the non-COVID ARDS group. A more severe COVID-19 presentation was associated with worse liver dysfunction and enhanced inflammatory activation; these parameters both correlated with abdominal (p = 0.04) and chest imaging measures (p = 0.03).
    Conclusion: In COVID-19 ARDS patients there are abdominal and lung vascular modifications that depict a portal hypertension-like pattern. The correlation between visceral vascular remodeling, pulmonary artery enlargement, and organ damage in these critically ill patients is consistent with a portal hyperlfow-like syndrome that could contribute to the peculiar characteristics of respiratory failure in these patients.
    Clinical relevance statement: our data suggest that the severity of COVID-19 lung involvement is directly related to the development of a portal hyperflow-like syndrome. These observations should help in defining the need for a closer monitoring, but also to develop dedicated therapeutic strategies.
    Language English
    Publishing date 2024-03-09
    Publishing country United States
    Document type Journal Article
    ZDB-ID 632818-0
    ISSN 1557-8615 ; 0883-9441
    ISSN (online) 1557-8615
    ISSN 0883-9441
    DOI 10.1016/j.jcrc.2024.154759
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Alkaline Liquid Ventilation of the Membrane Lung for Extracorporeal Carbon Dioxide Removal (ECCO

    Vivona, Luigi / Battistin, Michele / Carlesso, Eleonora / Langer, Thomas / Valsecchi, Carlo / Colombo, Sebastiano Maria / Todaro, Serena / Gatti, Stefano / Florio, Gaetano / Pesenti, Antonio / Grasselli, Giacomo / Zanella, Alberto

    Membranes

    2021  Volume 11, Issue 7

    Abstract: Extracorporeal carbon dioxide removal ( ... ...

    Abstract Extracorporeal carbon dioxide removal (ECCO
    Language English
    Publishing date 2021-06-22
    Publishing country Switzerland
    Document type Journal Article
    ISSN 2077-0375
    ISSN 2077-0375
    DOI 10.3390/membranes11070464
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Quantification of Recirculation During Veno-Venous Extracorporeal Membrane Oxygenation: In Vitro Evaluation of a Thermodilution Technique.

    Cipulli, Francesco / Battistin, Michele / Carlesso, Eleonora / Vivona, Luigi / Cadringher, Paolo / Todaro, Serena / Colombo, Sebastiano Maria / Lonati, Caterina / Fumagalli, Roberto / Pesenti, Antonio / Grasselli, Giacomo / Zanella, Alberto

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2021  Volume 68, Issue 2, Page(s) 184–189

    Abstract: Veno-venous extracorporeal membrane oxygenation (vv-ECMO) represents one of the most advanced respiratory support for patients suffering from severe acute respiratory distress syndrome. During vv-ECMO a certain amount of extracorporeal oxygenated blood ... ...

    Abstract Veno-venous extracorporeal membrane oxygenation (vv-ECMO) represents one of the most advanced respiratory support for patients suffering from severe acute respiratory distress syndrome. During vv-ECMO a certain amount of extracorporeal oxygenated blood can flow back from the reinfusion into the drainage cannula without delivering oxygen to the patient. Detection and quantification of this dynamic phenomenon, defined recirculation, are critical to optimize the ECMO efficiency. Our study aimed to measure the recirculation fraction (RF) using a thermodilution technique. We built an in vitro circuit to simulate patients undergoing vv-ECMO (ECMO flow: 1.5, 3, and 4.5 L/min) with different cardiac output, using a recirculation bridge to achieve several known RFs (from 0% to 50%). The RF, computed as the ratio of the area under temperature-time curves (AUC) of the drainage and reinfusion, was significantly related to the set RF (AUC ratio (%) = 0.979 × RF (%) + 0.277%, p < 0.0001), but it was not dependent on tested ECMO and cardiac output values. A Bland-Altman analysis showed an AUC ratio bias (precision) of -0.21% for the overall data. Test-retest reliability showed an intraclass correlation coefficient of 0.993. This study proved the technical feasibility and computation validity of the applied thermodilution technique in computing vv-ECMO RF.
    MeSH term(s) Cannula ; Extracorporeal Membrane Oxygenation/adverse effects ; Humans ; Reproducibility of Results ; Respiratory Distress Syndrome/therapy ; Thermodilution
    Language English
    Publishing date 2021-02-11
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000001428
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Evaluation of Left Ventricular Overload and Use of Unloading Techniques in Venoarterial Extracorporeal Life Support: A Nationwide Survey.

    Meani, Paolo / Veronese, Giacomo / Todaro, Serena / Marchese, Giuseppe / Mondellini, Giulio M / Protti, Ilaria / de Arroyabe, Blanca Martinez-Lopez / Epis, Francesco / Pappalardo, Federico / Pedrazzini, Giovanna / Munch, Christopher / Margari, Vito / Grazioli, Lorenzo / Lorini, Ferdinando Luca / Cattaneo, Sergio / Montisci, Andrea / Ballotta, Andrea / Raffa, Giuseppe Maria / Carboni, Pietro /
    Lucchelli, Matteo / Avalli, Leonello / Babuin, Luciano / Belliato, Mirko / Bertini, Pietro / Guarracino, Fabio / Paternoster, Gianluca / Ajello, Valentina / Catena, Emanuele / Scolletta, Sabino / Franchi, Federico / Musazzi, Andrea / Pacini, Davide / Sangalli, Fabio / Attisani, Matteo / Rinaldi, Mauro / Grasselli, Giacomo / Mondino, Michele / Ranucci, Marco / Lorusso, Roberto

    ASAIO journal (American Society for Artificial Internal Organs : 1992)

    2023  Volume 70, Issue 4, Page(s) e57–e60

    MeSH term(s) Humans ; Heart Failure/surgery ; Shock, Cardiogenic ; Heart Ventricles
    Language English
    Publishing date 2023-12-01
    Publishing country United States
    Document type Journal Article
    ZDB-ID 759982-1
    ISSN 1538-943X ; 0162-1432 ; 1058-2916
    ISSN (online) 1538-943X
    ISSN 0162-1432 ; 1058-2916
    DOI 10.1097/MAT.0000000000002113
    Database MEDical Literature Analysis and Retrieval System OnLINE

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