Article ; Online: Hypnotic prescription trends and patterns for the treatment of insomnia in Japan: analysis of a nationwide Japanese claims database.
2023 Volume 23, Issue 1, Page(s) 278
Abstract: Background: There is limited consensus regarding the optimal treatment of insomnia. The recent introduction of orexin receptor antagonists (ORA) has increased the available treatment options. However, the prescribing patterns of hypnotics in Japan have ... ...
Abstract | Background: There is limited consensus regarding the optimal treatment of insomnia. The recent introduction of orexin receptor antagonists (ORA) has increased the available treatment options. However, the prescribing patterns of hypnotics in Japan have not been comprehensively assessed. We performed analyses of a claims database to investigate the real-world use of hypnotics for treating insomnia in Japan. Methods: Data were retrieved for outpatients (aged ≥ 20 to < 75 years old) prescribed ≥ 1 hypnotic for a diagnosis of insomnia between April 1 Results: We analyzed data for 130,177 new and 91,215 long-term users (2010-2019). Most new users were prescribed one MOA per year (97.1%-97.9%). In 2010, GABA Conclusion: Prescriptions for hypnotics among new and long-term users in Japan showed distinct patterns and trends. Further understanding of the treatment options for insomnia with accumulating evidence for the risk-benefit balance might be beneficial for physicians prescribing hypnotics in real-world settings. |
---|---|
MeSH term(s) | Aged ; Humans ; Male ; Benzodiazepines/therapeutic use ; Drug Prescriptions/statistics & numerical data ; East Asian People ; Hypnotics and Sedatives/therapeutic use ; Japan/epidemiology ; Sleep Initiation and Maintenance Disorders/drug therapy ; Sleep Initiation and Maintenance Disorders/epidemiology ; Insurance Claim Review/statistics & numerical data ; Databases, Factual/statistics & numerical data ; Female ; Young Adult ; Adult ; Middle Aged ; Receptors, Melatonin/agonists ; GABA-A Receptor Agonists/therapeutic use ; Orexin Receptor Antagonists/therapeutic use ; Sleep Aids, Pharmaceutical/therapeutic use |
Chemical Substances | Benzodiazepines (12794-10-4) ; Hypnotics and Sedatives ; Receptors, Melatonin ; GABA-A Receptor Agonists ; Orexin Receptor Antagonists ; Sleep Aids, Pharmaceutical |
Language | English |
Publishing date | 2023-04-20 |
Publishing country | England |
Document type | Journal Article ; Research Support, Non-U.S. Gov't |
ZDB-ID | 2050438-X |
ISSN | 1471-244X ; 1471-244X |
ISSN (online) | 1471-244X |
ISSN | 1471-244X |
DOI | 10.1186/s12888-023-04683-2 |
Database | MEDical Literature Analysis and Retrieval System OnLINE |
More links
Kategorien
Order via subito
This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.