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  1. Article: Nutrivigilance: the road less traveled.

    Luthra, Vijay Ronit / Toklu, Hale Z

    Frontiers in pharmacology

    2023  Volume 14, Page(s) 1274810

    Language English
    Publishing date 2023-10-11
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2587355-6
    ISSN 1663-9812
    ISSN 1663-9812
    DOI 10.3389/fphar.2023.1274810
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Cosmetovigilance: A New Concept for the Residency Curriculum.

    Jones, Jennifer / Toklu, Hale Z

    HCA healthcare journal of medicine

    2020  Volume 1, Issue 4, Page(s) 181–183

    Abstract: Description Primary care physicians need to incorporate "cosmetovigilance" into their post-graduate curriculum to increase their residents' awareness of the adverse reactions induced by the use of cosmetic products, as well as promoting good reporting ... ...

    Abstract Description Primary care physicians need to incorporate "cosmetovigilance" into their post-graduate curriculum to increase their residents' awareness of the adverse reactions induced by the use of cosmetic products, as well as promoting good reporting behavior.
    Language English
    Publishing date 2020-08-29
    Publishing country United States
    Document type Editorial
    ISSN 2689-0216
    ISSN (online) 2689-0216
    DOI 10.36518/2689-0216.1112
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Research and Data Mining During the COVID-19 Pandemic.

    Toklu, Hale Z / Prashad, Rakesh

    HCA healthcare journal of medicine

    2020  Volume 1, Issue 5, Page(s) 253–255

    Abstract: Description With the recent advances in information and technology systems, most developed countries have invested in building advanced systems for the management of electronic medical records. If the infrastructure of these systems are well designed, ... ...

    Abstract Description With the recent advances in information and technology systems, most developed countries have invested in building advanced systems for the management of electronic medical records. If the infrastructure of these systems are well designed, they both serve as an information resource for routine patient care and also serve as the primary backbone for medical research. This evidence became clear during the recent coronavirus pandemic, which has been a worldwide challenge since the beginning of 2020. Rapid spread of SARS-CoV-2 infections all over the world has resulted in tremendous health, economic and social ramifications, including social distancing, travel restrictions and closing of schools and businesses. Medical educational activities have shifted towards telemedicine, online learning and web-based meetings and conferences to prevent virus spread. While experimental lab research slowed, research with electronic medical records and databases accelerated in order to investigate the risk factors associated with COVID-19 and clinical management strategies to combat the disease. The urgency for COVID-related research has also lead to inconsistent and sometimes inaccurate output.
    Language English
    Publishing date 2020-10-29
    Publishing country United States
    Document type Editorial
    ISSN 2689-0216
    ISSN (online) 2689-0216
    DOI 10.36518/2689-0216.1197
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Importance of Awareness of Adverse Drug Reaction Reporting During the COVID-19 Pandemic.

    Ellis, Heather / Toklu, Hale Z

    HCA healthcare journal of medicine

    2020  Volume 1, Issue 6, Page(s) 459–461

    Abstract: Description Health care professionals hold the responsibility of reporting any adverse drug reactions in order to learn about new therapy and how best to safely care for our patients. The information derived from case publications and FDA MedWatch ... ...

    Abstract Description Health care professionals hold the responsibility of reporting any adverse drug reactions in order to learn about new therapy and how best to safely care for our patients. The information derived from case publications and FDA MedWatch reports are essential to accumulate information and increase awareness for the possible risks of new drugs.
    Language English
    Publishing date 2020-12-29
    Publishing country United States
    Document type Editorial
    ISSN 2689-0216
    ISSN (online) 2689-0216
    DOI 10.36518/2689-0216.1206
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Concomitant Guillain-Barré Syndrome and COVID-19: A Meta-Analysis of Cases.

    Bentley, Skylar A / Ahmad, Sarfraz / Kobeissy, Firas H / Toklu, Hale Z

    Medicina (Kaunas, Lithuania)

    2022  Volume 58, Issue 12

    Abstract: Background and ... ...

    Abstract Background and Objectives
    Language English
    Publishing date 2022-12-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2188113-3
    ISSN 1648-9144 ; 1010-660X
    ISSN (online) 1648-9144
    ISSN 1010-660X
    DOI 10.3390/medicina58121835
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: A New Journal to Publish Houses of Bricks: Introducing the

    Toklu, Hale Z / Deighton, Bruce / Donini, Graig

    HCA healthcare journal of medicine

    2020  Volume 1, Issue 1, Page(s) 1–2

    Abstract: Description Welcome to ... ...

    Abstract Description Welcome to the
    Language English
    Publishing date 2020-02-27
    Publishing country United States
    Document type Editorial
    ISSN 2689-0216
    ISSN (online) 2689-0216
    DOI 10.36518/2689-0216.1046
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Can Neuron Specific Enolase Be a Diagnostic Biomarker for Neuronal Injury in COVID-19?

    Ganti, Latha / Serrano, Enrique / Toklu, Hale Z

    Cureus

    2020  Volume 12, Issue 10, Page(s) e11033

    Abstract: Neuron specific enolase (NSE) is a biomarker for neuronal injury. However, increased levels in cerebrospinal fluid (CSF) and serum is associated with the clinical outcome in patients with head injury, ischemic stroke, intracerebral hemorrhage, cardiac ... ...

    Abstract Neuron specific enolase (NSE) is a biomarker for neuronal injury. However, increased levels in cerebrospinal fluid (CSF) and serum is associated with the clinical outcome in patients with head injury, ischemic stroke, intracerebral hemorrhage, cardiac arrest, anoxic encephalopathy, encephalitis, brain metastasis, and status epilepticus. Recently, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which started in China, rapidly evolved into the coronavirus disease 2019 (COVID-19) pandemic. Patients with COVID-19 have a wide range of symptoms varying from mild upper respiratory symptoms to severe illness requiring mechanical ventilation. While coronaviruses primarily target the human respiratory system, neurological symptoms are also observed in some patients. These include symptoms such as loss of taste and olfaction and diseases like cerebrovascular disorders including ischemic stroke and hemorrhages, encephalopathies, Guillain-Barré syndrome and acute disseminated encephalomyelitis. Here we report an observation from a patient whose NSE levels increased approximately four-fold in CSF. This finding was accompanied by increased white blood cell count and elevated protein in CSF indicating neuroinflammation. Thus, we suggest that NSE may be used as a CSF biomarker in COVID-19 patients with encephalopathy.
    Keywords covid19
    Language English
    Publishing date 2020-10-19
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.11033
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Can Neuron Specific Enolase Be a Diagnostic Biomarker for Neuronal Injury in COVID-19?

    Ganti, Latha Serrano Enrique Toklu Hale Z.

    Cureus

    Abstract: Neuron specific enolase (NSE) is a biomarker for neuronal injury However, increased levels in cerebrospinal fluid (CSF) and serum is associated with the clinical outcome in patients with head injury, ischemic stroke, intracerebral hemorrhage, cardiac ... ...

    Abstract Neuron specific enolase (NSE) is a biomarker for neuronal injury However, increased levels in cerebrospinal fluid (CSF) and serum is associated with the clinical outcome in patients with head injury, ischemic stroke, intracerebral hemorrhage, cardiac arrest, anoxic encephalopathy, encephalitis, brain metastasis, and status epilepticus Recently, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, which started in China, rapidly evolved into the coronavirus disease 2019 (COVID-19) pandemic Patients with COVID-19 have a wide range of symptoms varying from mild upper respiratory symptoms to severe illness requiring mechanical ventilation While coronaviruses primarily target the human respiratory system, neurological symptoms are also observed in some patients These include symptoms such as loss of taste and olfaction and diseases like cerebrovascular disorders including ischemic stroke and hemorrhages, encephalopathies, Guillain- Barre syndrome and acute disseminated encephalomyelitis Here we report an observation from a patient whose NSE levels increased approximately four-fold in CSF This finding was accompanied by increased white blood cell count and elevated protein in CSF indicating neuroinflammation Thus, we suggest that NSE may be used as a CSF biomarker in COVID-19 patients with encephalopathy
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #902950
    Database COVID19

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  9. Article: Mentor-mentee Relationship: A Win-Win Contract In Graduate Medical Education.

    Toklu, Hale Z / Fuller, Jacklyn C

    Cureus

    2017  Volume 9, Issue 12, Page(s) e1908

    Abstract: Scholarly activities (i.e., the discovery of new knowledge; development of new technologies, methods, materials, or uses; integration of knowledge leading to new understanding) are intended to measure the quality and quantity of dissemination of ... ...

    Abstract Scholarly activities (i.e., the discovery of new knowledge; development of new technologies, methods, materials, or uses; integration of knowledge leading to new understanding) are intended to measure the quality and quantity of dissemination of knowledge. A successful mentorship program is necessary during residency to help residents achieve the six core competencies (patient care, medical knowledge, practice-based learning and improvement, systems-based practice, professionalism, interpersonal and communication skills) required by the Accreditation Council for Graduate Medical Education (ACGME). The role of the mentor in this process is pivotal in the advancement of the residents' knowledge about evidence-based medicine. With this process, while mentees become more self-regulated, exhibit confidence in their performance, and demonstrate more insight and aptitude in their jobs, mentors also achieve elevated higher self-esteem, enhanced leadership skills, and personal gratification. As such, we may conclude that mentoring is a two-sided relationship; i.e., a 'win-win' style of commitment between the mentor and mentee. Hence, both parties will eventually advance academically, as well as professionally.
    Language English
    Publishing date 2017-12-05
    Publishing country United States
    Document type Editorial
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.1908
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Why do we need pharmacists in pharmacovigilance systems?

    Toklu, Hale Z. / Mensah, Edward

    Online journal of public health informatics

    2016  Volume 8, Issue 2, Page(s) e193

    Abstract: Pharmacovigilance is the science and activity relating to the collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products. Pharmacovigilance basically targets safety of medicine. Pharmacists have crucial ... ...

    Abstract Pharmacovigilance is the science and activity relating to the collection, detection, assessment, monitoring, and prevention of adverse effects with pharmaceutical products. Pharmacovigilance basically targets safety of medicine. Pharmacists have crucial role in health systems to maintain the rational and safe use of medicine for they are drug experts who are specifically trained in this field. Effective use of pharmacists' workforce will improve the outcome of the pharmacotherapy as well as decrease global health costs. Given their advanced training, pharmacists can utilize pharmacovigilance systems interfaced with electronic health records to monitor the performance of the drugs they fill and also identify adverse drug reactions earlier than non-pharmacists, thereby reducing high healthcare costs.
    Language English
    Publishing date 2016-09-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2606835-7
    ISSN 1947-2579
    ISSN 1947-2579
    DOI 10.5210/ojphi.v8i2.6802
    Database MEDical Literature Analysis and Retrieval System OnLINE

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