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  1. Article: Technical success, procedural safety, and efficacy of the Silk Vista Baby in the treatment of cerebral aneurysms over a mid-to-long-term follow-up.

    Rodríguez-Fernández, Claudio / Ruiz-Garcia, Pedro / Garcia-Sanchez, Maria Jesús / Manrique-Zegarra, Martiel / Toledano-Illán, Carlos / Escartin, Jorge / Vences, Miguel Angel / Rubio, Luis Angel / Luttich, Alex / Pumar, José Manuel

    Frontiers in neurology

    2024  Volume 15, Page(s) 1369443

    Abstract: Background: Long-term follow-up of cerebral aneurysms treated with the Silk Vista Baby (SVB) flow diverter is lacking. This study aimed to assess the technical success, procedural safety, and efficacy of the SVB (Balt, Montmorency, France) for the ... ...

    Abstract Background: Long-term follow-up of cerebral aneurysms treated with the Silk Vista Baby (SVB) flow diverter is lacking. This study aimed to assess the technical success, procedural safety, and efficacy of the SVB (Balt, Montmorency, France) for the treatment of intracranial aneurysms in small cerebral vessels over a mid-to long-term follow-up.
    Methods: We retrospectively analyzed a prospectively maintained database of patients treated with the SVB between September 2018 and June 2021. Data regarding patient demographics, aneurysm characteristics, and technical procedures were also collected. Angiographic and clinical findings were recorded during the procedure and over a period of at least 12 months.
    Results: Angiographic and clinical follow-up data were available for 50 patients/50 aneurysms. The procedural complication rate was 8%. At 12 months, the final results showed a technical success rate of 100%, the re rupture rate was 0%, neuromorbidity and mortality rates of 4 and 0%, respectively, and an almost complete occlusion rate of 94%.
    Conclusion: Treatment of complex intracranial aneurysms with the SVB was safe and effective. Long-term results showed high rates of adequate and stable occlusions.
    Language English
    Publishing date 2024-03-27
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2564214-5
    ISSN 1664-2295
    ISSN 1664-2295
    DOI 10.3389/fneur.2024.1369443
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Nivolumab and Ipilimumab-induced myositis and myocarditis mimicking a myasthenia gravis presentation.

    Valenti-Azcarate, Rafael / Esparragosa Vazquez, Ines / Toledano Illan, Carlos / Idoate Gastearena, Miguel Angel / Gállego Pérez-Larraya, Jaime

    Neuromuscular disorders : NMD

    2019  Volume 30, Issue 1, Page(s) 67–69

    Abstract: The rapidly growing field of cancer immunotherapy has led to the development of new treatments such as immune checkpoint inhibitors. These agents are monoclonal antibodies that enable tumor-reactive T cells to overcome regulatory mechanisms and produce ... ...

    Abstract The rapidly growing field of cancer immunotherapy has led to the development of new treatments such as immune checkpoint inhibitors. These agents are monoclonal antibodies that enable tumor-reactive T cells to overcome regulatory mechanisms and produce effective antitumor responses. The use of immune checkpoint inhibitors is expected to progressively increase because they have shown promising therapeutic outcomes in multiple types of cancer and clinicians should be aware of their possible side-effects. We report a case of a man diagnosed with a non-microcytic lung carcinoma who started treatment with a combination of immune checkpoint inhibitors (Nivolumab and Ipilimumab). He subsequently developed binocular diplopia, fatigue, mild dyspnea and upper back pain resembling a myasthenia gravis presentation. Finally, a diagnosis of immune checkpoint inhibitor-related myositis and myocarditis was made. The detection of GFAP antibodies in CSF has unclear clinical and pathogenic significance and they may rather represent an epiphenomenon of the immune inflammation process.
    MeSH term(s) Aged ; Antineoplastic Agents, Immunological/adverse effects ; Humans ; Immune Checkpoint Inhibitors/adverse effects ; Ipilimumab/adverse effects ; Lung Neoplasms/drug therapy ; Male ; Myasthenia Gravis/chemically induced ; Myasthenia Gravis/diagnosis ; Myocarditis/chemically induced ; Myocarditis/diagnosis ; Myositis/chemically induced ; Myositis/diagnosis ; Nivolumab/adverse effects
    Chemical Substances Antineoplastic Agents, Immunological ; Immune Checkpoint Inhibitors ; Ipilimumab ; Nivolumab (31YO63LBSN)
    Language English
    Publishing date 2019-11-04
    Publishing country England
    Document type Case Reports
    ZDB-ID 1077681-3
    ISSN 1873-2364 ; 0960-8966
    ISSN (online) 1873-2364
    ISSN 0960-8966
    DOI 10.1016/j.nmd.2019.10.006
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Autoimmune glial fibrillary acidic protein astrocytopathy: case report of a treatable cause of rapidly progressive dementia.

    Toledano-Illán, Carlos / Esparragosa Vázquez, Inés / Zelaya Huerta, María Victoria / Rosales Castillo, Juan José / Paternain Nuin, Alberto / Arbizu Lostao, Javier / García de Eulate, María Reyes / Riverol Fernández, Mario

    Journal of neurology

    2021  Volume 268, Issue 6, Page(s) 2256–2258

    MeSH term(s) Astrocytes ; Autoimmune Diseases of the Nervous System ; Dementia/etiology ; Glial Fibrillary Acidic Protein ; Humans ; Intermediate Filaments
    Chemical Substances Glial Fibrillary Acidic Protein
    Language English
    Publishing date 2021-02-26
    Publishing country Germany
    Document type Case Reports ; Letter
    ZDB-ID 187050-6
    ISSN 1432-1459 ; 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    ISSN (online) 1432-1459
    ISSN 0340-5354 ; 0012-1037 ; 0939-1517 ; 1619-800X
    DOI 10.1007/s00415-021-10484-y
    Database MEDical Literature Analysis and Retrieval System OnLINE

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