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Book ; Online: A relevance perspective of promising in medical utilitarian texts of the earl y modern english period. Núm 5

Quintana Toledo, Elena

2020

Keywords	ELT background & reference material
Size	1 electronic resource (152 pages)
Publisher	Universitat Politècnica de València Editorial
Publishing place	Valencia
Document type	Book ; Online
Note	English ; Open Access
HBZ-ID	HT021290500
Database	ZB MED Catalogue: Medicine, Health, Nutrition, Environment, Agriculture

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Article: Consumption of Fruit or Fiber-Fruit Decreases the Risk of Cardiovascular Disease in a Mediterranean Young Cohort

Ruiz-Canela, Miguel / Toledo, Estefania

Nutrients, 9(3):295

2017

Abstract: Fiber and fiber-rich foods have been inversely associated with cardiovascular disease (CVD), but the evidence is scarce in young and Mediterranean cohorts. We used Cox regression models to assess the association between quintiles of total fiber and fiber ...

Abstract	Fiber and fiber-rich foods have been inversely associated with cardiovascular disease (CVD), but the evidence is scarce in young and Mediterranean cohorts. We used Cox regression models to assess the association between quintiles of total fiber and fiber from different sources, and the risk of CVD adjusted for the principal confounding factors in a Mediterranean cohort of young adults, the SUN (Seguimiento Universidad de Navarra, Follow-up) cohort. After a median follow-up of 10.3 years, we observed 112 cases of CVD among 17,007 participants (61% female, mean age 38 years). We observed an inverse association between fiber intake and CVD events (p for trend = 0.024) and also between the highest quintile of fruit consumption (hazard ratio (HR) 0.51, 95% confidence interval (CI) 0.27–0.95) or whole grains consumption (HR 0.43 95% CI 0.20–0.93) and CVD compared to the lowest quintile, and also a HR of 0.58 (95% CI 0.37–0.90) for the participants who ate at least 175 g/day of fruit. Only the participants in the highest quintile of fruit-derived fiber intake had a significantly lower risk of CVD (HR 0.52, 95% CI 0.28–0.97). The participants who ate at least one serving per week of cruciferous vegetables had a lower risk than those who did not (HR 0.52, 95% CI 0.30–0.89). In conclusion, high fruit consumption, whole grain consumption, or consumption of at least one serving/week of cruciferous vegetables may be protective against CVD in young Mediterranean populations.
Keywords	cardiovascular disease ; fiber ; fruit ; legumes ; whole grains ; vegetables
Language	English
Document type	Article
Database	Repository for Life Sciences

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Article ; Online: Lipidome and inflammation interplay: the role of diet in this relationship.

Rovayo, Anacristina / Toledo, Estefanía / Razquin, Cristina

Current opinion in lipidology

2023 Volume 35, Issue 1, Page(s) 20–24

Abstract: Purpose of review: The aim of this review was to provide an overview of the role of novel lipid biomarkers from the circulating lipidome in inflammatory processes and the impact that dietary patterns may have on the lipidome.: Recent findings: ... ...

Abstract	Purpose of review: The aim of this review was to provide an overview of the role of novel lipid biomarkers from the circulating lipidome in inflammatory processes and the impact that dietary patterns may have on the lipidome. Recent findings: Inflammation is a process that underlies many acute and chronic diseases, contributing to their development and severity. Finding novel molecules which serve as biomarkers and which are involved in inflammation is very useful, since they offer us both preventive or therapeutic targets and reveal mechanisms of action. Recently, several studies have found circulating lipid molecules that are implicated in inflammatory processes of different diseases, such as cardiovascular diseases, type 2 diabetes, COVID-19 or other respiratory infectious diseases. As such, ceramides, triacylglicerides or lysophosphatidylcholines have been associated with inflammation in a different manner depending on the stage of inflammation. The study of dietary patterns, especially healthy ones as the Mediterranean or the Nordic diets, has shown the impact that dietary habits may have on the lipidomic profile of individuals. Conclusions: Healthy dietary patterns have been suggested to exert beneficial effects in the circulating lipid profile. Studying the circulating lipidome could help to find new biomarkers of underlying inflammation, especially in cases of chronic low-grade inflammatory diseases in which it is more difficult to detect.
MeSH term(s)	Humans ; Lipidomics ; Diabetes Mellitus, Type 2 ; Diet ; Inflammation ; Biomarkers ; Ceramides ; Diet, Mediterranean
Chemical Substances	Biomarkers ; Ceramides
Language	English
Publishing date	2023-11-08
Publishing country	England
Document type	Review ; Journal Article
ZDB-ID	1045394-5
ISSN	1473-6535 ; 0957-9672
ISSN (online)	1473-6535
ISSN	0957-9672
DOI	10.1097/MOL.0000000000000909
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article: Production of Protein Concentrates from Macauba (

Toledo E Silva, Sérgio Henrique / Silva, Lidiane Bataglia / Eisner, Peter / Bader-Mittermaier, Stephanie

Foods (Basel, Switzerland)

2022 Volume 11, Issue 22

Abstract: Macauba palm fruits ( ...

Abstract	Macauba palm fruits (
Language	English
Publishing date	2022-11-12
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	2704223-6
ISSN	2304-8158
ISSN	2304-8158
DOI	10.3390/foods11223608
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Article ; Online: [No title information]

Nievas, Claudia Mariela / Gandini, Bernardo J / Toledo, Eugenia / Albornoz, Johanna

Revista de la Facultad de Ciencias Medicas (Cordoba, Argentina)

2023 Volume 80, Issue 4, Page(s) 385–403

Abstract: Introduction: Adolescent health is currently undergoing a serious deterioration. The aim of this study was to identify the self-care practices in adolescents between 15 and 18 years of age attending secondary schools in four departments of the interior ... ...

Title translation	El autocuidado de salud en adolescentes del interior argentino.
Abstract	Introduction: Adolescent health is currently undergoing a serious deterioration. The aim of this study was to identify the self-care practices in adolescents between 15 and 18 years of age attending secondary schools in four departments of the interior of the province of La Rioja, Argentina. Methodology: descriptive cross-sectional and analytical study; data collected between October and November 2022 by non-probabilistic convenience sampling, with analysis of absolute and relative frequencies, multivariate logistic regression analysis and Odds ratio with 95% CI statistical significance of p= ˂0.05. Exploratory factor analysis (EFA) using the Principal Components method as extraction and the Orthogonal Varimax method as rotation. Analysis software, SPSS version 26. Results: There are discordances between the self-perception of health care and the practice carried out by the adolescents. Gender disparity in self-care is identified. The factors that increase self-care are the use of digital health applications, annual or shorter medical check-ups, and maintaining positive thinking habits. The main concern in relation to self-care among adolescents was the consumption of alcoholic beverages.
MeSH term(s)	Humans ; Adolescent ; Self Care ; Argentina
Language	Spanish
Publishing date	2023-12-26
Publishing country	Argentina
Document type	English Abstract ; Journal Article
ZDB-ID	390127-0
ISSN	1853-0605 ; 0014-6722 ; 0301-7281
ISSN (online)	1853-0605
ISSN	0014-6722 ; 0301-7281
DOI	10.31053/1853.0605.v80.n4.41091
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Article: In search of wind farm sustainability on the Yucatan coast: Deficiencies and public perception of Environmental Impact Assessment in Mexico

Zárate-Toledo, Ezequiel / Wood, Paul / Patiño, Rodrigo

Energy policy. 2021 Nov., v. 158

2021

Abstract: Through the analysis of the corresponding Environmental Impact Assessment (EIA) for five wind projects set up on the Yucatan coast, in Mexico, this work seeks to draw attention to the environmental controversies that these projects generate. To carry out ...

Abstract	Through the analysis of the corresponding Environmental Impact Assessment (EIA) for five wind projects set up on the Yucatan coast, in Mexico, this work seeks to draw attention to the environmental controversies that these projects generate. To carry out our analysis, we resorted to three sources of information that are part of the EIA process: (i) the Environmental Impact Statement (EIS), presented by private companies, for these wind farms; (ii) observations and criticisms of the EIS, presented by the civil society during the public process to which the EIS is submitted; and (iii) the rulings emitted by the federal environmental authorities. This documentation was complemented by participation in a number of forums and some interviews. Based on this analysis, we defined a series of deficiencies in the EIA process. Accordingly, we can affirm that in Mexico, as in other countries, there is no wind energy plan capable of reconciling energy objectives with nature conservation. Renewable energy projects in Mexico have been designed solely based on the distribution of wind or solar resources, completely ignoring environmental or social issues. In this regard, a sustainable energy transition requires strengthening the environmental management capabilities of governments, and the application of mechanisms that will allow the integration of environmental variables in the early stages of decision making, using instruments such as the Strategic Environmental Assessment.
Keywords	coasts ; energy ; energy policy ; environmental assessment ; environmental impact ; natural resources conservation ; public opinion ; society ; wind ; wind farms ; wind power ; Mexico
Language	English
Dates of publication	2021-11
Publishing place	Elsevier Ltd
Document type	Article
ISSN	0301-4215
DOI	10.1016/j.enpol.2021.112525
Database	NAL-Catalogue (AGRICOLA)

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Article ; Online: Persistence of RNA Viruses in the Respiratory Tract: An Overview.

Santiago-Olivares, Carlos / Martínez-Alvarado, Eber / Rivera-Toledo, Evelyn

Viral immunology

2022 Volume 36, Issue 1, Page(s) 3–12

Abstract: Respiratory RNA viruses are a major cause of acute lower respiratory tract infections and contribute substantially to hospitalization among infants, elderly, and immunocompromised. Complete viral clearance from acute infections is not always achieved, ... ...

Abstract	Respiratory RNA viruses are a major cause of acute lower respiratory tract infections and contribute substantially to hospitalization among infants, elderly, and immunocompromised. Complete viral clearance from acute infections is not always achieved, leading to persistence. Certain chronic respiratory diseases like asthma and chronic obstructive pulmonary disease have been associated with persistent infection by human respiratory syncytial virus and human rhinovirus, but it is still not clear whether RNA viruses really establish long-term infections as it has been recognized for DNA viruses as human bocavirus and adenoviruses. Herein, we summarize evidence of RNA virus persistence in the human respiratory tract, as well as in some animal models, to highlight how long-term infections might be related to development and/or maintenance of chronic respiratory symptoms.
MeSH term(s)	Infant ; Humans ; Aged ; Respiratory System ; Respiratory Tract Infections ; RNA Viruses ; Respiratory Syncytial Virus, Human ; Asthma
Language	English
Publishing date	2022-11-11
Publishing country	United States
Document type	Journal Article ; Review ; Research Support, Non-U.S. Gov't
ZDB-ID	639075-4
ISSN	1557-8976 ; 0882-8245
ISSN (online)	1557-8976
ISSN	0882-8245
DOI	10.1089/vim.2022.0135
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Article ; Online: A Novel Approach for Colloidal Lithography: From Dry Particle Assembly to High-Throughput Nanofabrication.

Tzadka, Sivan / Ureña Martin, Carlos / Toledo, Esti / Yassin, Abed Al Kader / Pandey, Ashish / Le Saux, Guillaume / Porgador, Angel / Schvartzman, Mark

ACS applied materials & interfaces

2024 Volume 16, Issue 14, Page(s) 17846–17856

Abstract: We introduce a novel approach for colloidal lithography based on the dry particle assembly into a dense monolayer on an elastomer, followed by mechanical transfer to a substrate of any material and curvature. This method can be implemented either ... ...

Abstract	We introduce a novel approach for colloidal lithography based on the dry particle assembly into a dense monolayer on an elastomer, followed by mechanical transfer to a substrate of any material and curvature. This method can be implemented either manually or automatically and it produces large area patterns with the quality obtained by the state-of-the-art colloidal lithography at a very high throughput. We first demonstrated the fabrication of nanopatterns with a periodicity ranging between 200 nm and 2 μm. We then demonstrated two nanotechnological applications of this approach. The first one is antireflective structures, fabricated on silicon and sapphire, with different geometries including arrays of bumps and holes and adjusted for different spectral ranges. The second one is smart 3D nanostructures for mechanostimulation of T cells that are used for their effective proliferation, with potential application in cancer immunotherapy. This new approach unleashes the potential of bottom-up nanofabrication and paves the way for nanoscale devices and systems in numerous applications.
Language	English
Publishing date	2024-03-28
Publishing country	United States
Document type	Journal Article
ISSN	1944-8252
ISSN (online)	1944-8252
DOI	10.1021/acsami.3c18554
Database	MEDical Literature Analysis and Retrieval System OnLINE

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Article ; Online: Production of Protein Concentrates from Macauba (Acrocomia aculeata and Acrocomia totai) Kernels by Sieve Fractionation

Toledo e Silva, Sérgio Henrique De / Bataglia da Silva, Lidiane / Eisner, Peter / Mittermaier, Stephanie

2022

Abstract: Macauba palm fruits (Acrocomia aculeata and Acrocomia totai) are emerging as sources of high-quality oils from their pulp and kernels. The protein-rich macauba kernel meal (MKM) left after oil extraction remains undervalued, mainly due to the lack of ... ...

Abstract	Macauba palm fruits (Acrocomia aculeata and Acrocomia totai) are emerging as sources of high-quality oils from their pulp and kernels. The protein-rich macauba kernel meal (MKM) left after oil extraction remains undervalued, mainly due to the lack of suitable deoiling parameters and integrated protein recovery methods. Therefore, the present study aimed to produce protein concentrates from MKM using sieve fractionation. The deoiling parameters, comprising pressing, milling, and solvent extraction, were improved in terms of MKM functionality. The combination of hydraulic pressing, milling to 1 mm, and the hexane extraction of A. aculeata kernels resulted in MKM with the highest protein solubility (77.1%), emulsifying activity index (181 m2/g protein), and emulsion stability (149 min). After sieve fractionation (cut size of 62 µm), this meal yielded a protein concentrate with a protein content of 65.6%, representing a 74.1% protein enrichment compared to the initial MKM. This protein concentrate showed a reduced gelling concentration from 8 to 6%, and an increased emulsion stability from 149 to 345 min, in comparison to the MKM before sieving. Therefore, sieve fractionation after improved deoiling allows for the simple, cheap, and environmentally friendly recovery of MKM proteins, highlighting the potential of macauba kernels as a new source of protein. 11 22
Keywords	bocaiuva ; oilseed proteins ; dry fractionation ; plant-based ; industrial by-products ; functional
Subject code	571
Language	English
Publishing country	de
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

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Article ; Online: Health-related quality of life and mortality in the 'Seguimiento Universidad de Navarra' prospective cohort study.

López-Herreros, J / Martínez-González, M A / Gea, A / Sánchez-Villegas, A / Dierssen-Sotos, T / Jiménez-Moleón, J J / Ruiz-Canela, M / Toledo, E

Experimental gerontology

2023 Volume 178, Page(s) 112224

Abstract: Objective: To study the association between health-related quality of life (HRQoL) and all-cause mortality in a healthy middle-aged Mediterranean cohort.: Methods: We included 15,390 participants -mean age 42.8 years at first HRQoL ascertainment, all ...

Abstract	Objective: To study the association between health-related quality of life (HRQoL) and all-cause mortality in a healthy middle-aged Mediterranean cohort. Methods: We included 15,390 participants -mean age 42.8 years at first HRQoL ascertainment, all university graduates-. HRQoL was assessed with the self-administered Medical Outcomes Study Short Form-36 (SF-36) twice, with a 4-year gap. We used multivariable-adjusted Cox regression models to address the relation between self-reported health and Physical or Mental Component Summary (PCS-36 or MCS-36) and mortality, and their interaction with prior comorbidities or adherence to the Mediterranean diet (MedDiet). Results: Over 8.7 years of median follow-up time, 266 deaths were identified. Hazard ratio (HR) for the excellent vs. poor/fair category in self-reported health was 0.30 (95 % confidence interval (CI), 0.16-0.57) in the model with repeated measurements of HRQoL. Both the PCS-36 (HR Conclusions: Self-reported HRQoL -assessed as self-reported health, PCS-36 and MCS-36- obtained with the Spanish version of the SF-36 were inversely associated with mortality risk, regardless of the presence of previous comorbidities or adherence to the MedDiet.
MeSH term(s)	Humans ; Middle Aged ; Quality of Life ; Prospective Studies ; Health Status ; Self Report ; Comorbidity ; Diet, Mediterranean ; Spain/epidemiology ; Surveys and Questionnaires
Language	English
Publishing date	2023-05-31
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	390992-x
ISSN	1873-6815 ; 0531-5565
ISSN (online)	1873-6815
ISSN	0531-5565
DOI	10.1016/j.exger.2023.112224
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