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Book ; Online: Volatile knowing

Tollefson, Kaia

parents, teachers, and the censored story of accountability in America's public schools

2008

Abstract: Volatile Knowing refers to the positive change that can result when parents and teachers talk together about the politics of school reform. Based on a study of teachers and parents who researched aspects of the accountability movement typically censored ... ...

Institution	ebrary, Inc
Author's details	Kaia Tollefson; foreword by Maxine Greene
Abstract	Volatile Knowing refers to the positive change that can result when parents and teachers talk together about the politics of school reform. Based on a study of teachers and parents who researched aspects of the accountability movement typically censored in mainstream media, Volatile Knowing reveals the hidden power behind current reform efforts that serve private, not public interests. It is aimed at provoking a new, child-centered movement for accountability and creativity in the nation's schools
Keywords	Educational accountability ; Public schools
Language	English
Size	Online-Ressource (xii, 209 p), ill
Publisher	Lexington Books
Publishing place	Lanham, Md
Document type	Book ; Online
Note	First paperback edition 2010 ; Includes bibliographical references and index
ISBN	0739115596 ; 9780739115596 ; 9780739115602 ; 073911560X
Database	Library catalogue of the German National Library of Science and Technology (TIB), Hannover

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Article: pH-dependent oxidant production following inhibition of the mitochondrial electron transport chain in pulmonary endothelial cells.

Cutaia, M / Kroczynski, J / Tollefson, K

Endothelium : journal of endothelial cell research

2002 Volume 9, Issue 2, Page(s) 109–121

Abstract: We investigated the effect of changes in intracellular pH (pHi) and Na/H antiport activity on intracellular oxidant production in human pulmonary artery endothelial cells (HPAEC) following disruption of cellular metabolism. Oxidant production was ... ...

Abstract	We investigated the effect of changes in intracellular pH (pHi) and Na/H antiport activity on intracellular oxidant production in human pulmonary artery endothelial cells (HPAEC) following disruption of cellular metabolism. Oxidant production was measured with oxidant-sensitive probes (2',7'-dichlorofluorescein diacetate [H2DCF], dihydroethidium [DHE]) following treatment with inhibitors of mitochondrial electron transport and glycolysis (antimycin/2-deoxyglucose, A/D). A/D treatment increased oxidant production in a dose-dependent fashion over 2 hours. Omission of 2-deoxyglucose did not alter the magnitude of oxidant production. Inhibition at more proximal sites in the mitochondrial electron transport chain inhibited oxidant production. These data suggested that the mitochondrial electron transport chain was the source of oxidant production. Fluorescent imaging experiments confirmed the mitochondrial origin of the increased oxidant production under these conditions. Maneuvers that reduced pHi and inhibited Na/H exchange (acidosis, specific Na/H exchange inhibitors) attenuated oxidant production, whereas maneuvers that raised pHi (monensin) potentiated oxidant production. The results with the pH-insensitive probe (DHE) confirmed that oxidant production was pH-dependent. Oxidant production preceded significant loss of cell viability at 6 h following A/D treatment. These results demonstrate that oxidant production following inhibition of mitochondrial electron transport in HPAEC is pH-dependent and may contribute to endothelial cell injury by increasing endogenous oxidative stress.
MeSH term(s)	Antimycin A/analogs & derivatives ; Antimycin A/pharmacology ; Cell Survival/drug effects ; Cells, Cultured ; Deoxyglucose/pharmacology ; Electron Transport/drug effects ; Endothelium, Vascular/cytology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/metabolism ; Fluorescent Dyes ; Glycolysis/drug effects ; Humans ; Hydrogen-Ion Concentration ; Mitochondria/drug effects ; Mitochondria/metabolism ; Oxidants/metabolism ; Sodium-Hydrogen Exchangers/antagonists & inhibitors ; Sodium-Hydrogen Exchangers/metabolism
Chemical Substances	Fluorescent Dyes ; Oxidants ; Sodium-Hydrogen Exchangers ; antimycin (11118-72-2) ; Antimycin A (642-15-9) ; Deoxyglucose (9G2MP84A8W)
Language	English
Publishing date	2002-08-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1230639-3
ISSN	1543-5261 ; 1062-3329
ISSN (online)	1543-5261
ISSN	1062-3329
DOI	10.1080/10623320212007
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Article ; Online: Beta2 integrins modulate the initiation and progression of atherosclerosis in low-density lipoprotein receptor knockout mice.

Merched, Aksam / Tollefson, Katherine / Chan, Lawrence

Cardiovascular research

2009 Volume 85, Issue 4, Page(s) 853–863

Abstract: Aims: Beta2 integrin-mediated adhesion is thought to be a key event in cardiovascular disease. However, results of clinical trials targeting these molecules have been disappointing. Here, we investigated the effect of inactivation of beta2 integrins at ... ...

Abstract	Aims: Beta2 integrin-mediated adhesion is thought to be a key event in cardiovascular disease. However, results of clinical trials targeting these molecules have been disappointing. Here, we investigated the effect of inactivation of beta2 integrins at different stages of atherosclerosis by timed bone marrow transplantation (BMT) of CD18(-/-) cells in low-density lipoprotein receptor knockout (LDLR(-/-)) mice. Methods and results: Early BMT before fatty streak formation revealed a short-term protective effect of CD18 (34% atherosclerotic lesion reduction). Once fatty streak lesions had developed (5-week atherogenic diet) before BMT, beta2 integrin expression did not affect lesion progression. However, after the establishment of more mature lesions (pre-feeding mice the atherogenic diet for 10 weeks), CD18(+/+) BMT enhanced atherosclerosis (36%) lesion progression compared with CD18(-/-) BMT. Furthermore, beta2 integrins modulated the capacity of isolated peritoneal macrophages to take up acetylated LDL and native LDL and to phagocytose apoptotic cells, possibly via CD18-dependent mitogen-activated protein kinase signalling. Gene expression profile of CD18(-/-) and CD18(+/+) macrophages revealed significant differences in putative protective as well as atherogenic functions. Conclusion: beta2 integrin-mediated interaction between leucocytes and the vessel wall is a time-dependent and dynamic process. During the initiation phase, it protects against atherosclerotic lesion formation. However, with the evolution of the lesion and chronic exposure to dyslipidaemia, beta2 integrins' pro-atherogenic action becomes dominant, accelerating the atherosclerotic process.
MeSH term(s)	Animals ; Apoptosis/physiology ; Atherosclerosis/immunology ; Atherosclerosis/metabolism ; Atherosclerosis/physiopathology ; Bone Marrow Transplantation ; CD18 Antigens/genetics ; CD18 Antigens/metabolism ; Disease Progression ; Dyslipidemias/immunology ; Dyslipidemias/metabolism ; Dyslipidemias/physiopathology ; Female ; Lipoproteins, LDL ; Macrophages, Peritoneal/physiology ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Phagocytosis/physiology ; Receptors, LDL/genetics ; Receptors, LDL/metabolism ; Vasculitis/immunology ; Vasculitis/metabolism ; Vasculitis/physiopathology
Chemical Substances	CD18 Antigens ; Lipoproteins, LDL ; Receptors, LDL
Language	English
Publishing date	2009-10-20
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	80340-6
ISSN	1755-3245 ; 0008-6363
ISSN (online)	1755-3245
ISSN	0008-6363
DOI	10.1093/cvr/cvp347
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Article: Inhibition of apoptosis in pulmonary endothelial cells by altered pH, mitochondrial function, and ATP supply.

Terminella, C / Tollefson, K / Kroczynski, J / Pelli, J / Cutaia, M

American journal of physiology. Lung cellular and molecular physiology

2002 Volume 283, Issue 6, Page(s) L1291–302

Abstract: We investigated the effect of altered extracellular pH, mitochondrial function, and ATP content on development of apoptosis in human pulmonary artery endothelial cells after treatment with staurosporine (STS). STS produced a concentration- and time- ... ...

Abstract	We investigated the effect of altered extracellular pH, mitochondrial function, and ATP content on development of apoptosis in human pulmonary artery endothelial cells after treatment with staurosporine (STS). STS produced a concentration- and time-dependent increase in caspase-3 activity in pH 7.4 medium that reached a peak at 6 h. The increase in caspase activity was associated with significant DNA fragmentation. Fluorescent imaging of treated monolayers in pH 7.4 medium with Hoechst-33342-propidium iodide demonstrated a large percentage of apoptotic cells ( approximately 40%) with no evidence of necrosis. Caspase activity, DNA fragmentation, and percentage of apoptotic cells were reduced after STS treatment in acidic media (pH 7.0 and 6.6). The Ca2+ chelator 1,2-bis(2-aminophenoxy)ethane-N,N,N',N'-tetraacetic acid-AM inhibited STS-induced apoptosis, whereas the rise in intracellular Ca2+concentration in STS-treated cells in pH 7.4 medium was reduced in pH 7.0 medium. These results suggest that one mechanism for inhibitory effects of acidosis may be a pH-induced alteration in Ca2+ signaling. Treatment with STS in the presence of oligomycin (10 microM), an inhibitor of the mitochondrial F(0)F(1)-ATPase, in glucose-free media abolished caspase activation and DNA fragmentation in association with severe ATP depletion ( approximately 2% of control cells). Imaging demonstrated a change in the mode of cell death from apoptosis to necrosis under these conditions. This change was linked to the level of ATP depletion, because STS treatment in the absence of glucose or the presence of oligomycin in media with glucose still leads to apoptosis in the presence of only moderate ATP depletion. These results demonstrate that pH, mitochondrial function, and ATP supply are important variables that regulate STS-induced apoptosis in human pulmonary artery endothelial cells.
MeSH term(s)	Adenosine Triphosphate/deficiency ; Adenosine Triphosphate/physiology ; Apoptosis/drug effects ; Apoptosis/physiology ; Calcium/metabolism ; Caspase 3 ; Caspases/metabolism ; Cells, Cultured ; Cytosol/metabolism ; DNA Fragmentation/physiology ; Endothelium, Vascular/cytology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/physiology ; Enzyme Activation ; Enzyme Inhibitors/pharmacology ; Humans ; Hydrogen/metabolism ; Hydrogen-Ion Concentration ; Mitochondria/physiology ; Pulmonary Artery/cytology ; Pulmonary Artery/drug effects ; Pulmonary Artery/physiology ; Staurosporine/pharmacology
Chemical Substances	Enzyme Inhibitors ; Hydrogen (7YNJ3PO35Z) ; Adenosine Triphosphate (8L70Q75FXE) ; CASP3 protein, human (EC 3.4.22.-) ; Caspase 3 (EC 3.4.22.-) ; Caspases (EC 3.4.22.-) ; Staurosporine (H88EPA0A3N) ; Calcium (SY7Q814VUP)
Language	English
Publishing date	2002-11-07
Publishing country	United States
Document type	Journal Article ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	1013184-x
ISSN	1522-1504 ; 1040-0605
ISSN (online)	1522-1504
ISSN	1040-0605
DOI	10.1152/ajplung.00246.2001
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Article: Role of the Na/H antiport in pH-dependent cell death in pulmonary artery endothelial cells.

Cutaia, M / Tollefson, K / Kroczynski, J / Parks, N / Rounds, S

American journal of physiology. Lung cellular and molecular physiology

2000 Volume 278, Issue 3, Page(s) L536–44

Abstract: We investigated the role of intracellular pH (pH(i)) and Na/H exchange in cell death in human pulmonary artery endothelial cells (HPAEC) following a metabolic insult (inhibition-oxidative phosphorylation, glycolysis). Metabolic inhibition in medium at pH ...

Abstract	We investigated the role of intracellular pH (pH(i)) and Na/H exchange in cell death in human pulmonary artery endothelial cells (HPAEC) following a metabolic insult (inhibition-oxidative phosphorylation, glycolysis). Metabolic inhibition in medium at pH 7. 4 decreased viability (0-15% live cells) over 6 h. Cell death was attenuated by maneuvers that decreased pH(i) and inhibited Na/H exchange (acidosis, Na/H antiport inhibitors). In contrast, cell death was potentiated by maneuvers that elevated pH(i) or increased Na/H exchange (monensin, phorbol ester treatment) before the insult. HPAEC demonstrated a biphasic pH(i) response following a metabolic insult. An initial decrease in pH(i) was followed by a return to baseline over 60 min. Maneuvers that protected HPAEC and inhibited Na/H exchange (acidosis, Na(+)-free medium, antiport inhibitors) altered this pattern. pH(i) decreased, but no recovery was observed, suggesting that the return of pH(i) to normal was mediated by antiport activation. Although Na/H antiport activity was reduced (55-60% of control) following a metabolic insult, the cells still demonstrated active Na/H exchange despite significant ATP depletion. Phorbol ester pretreatment, which potentiated cell death, increased Na/H antiport activity above the level observed in monolayers subjected to a metabolic insult alone. These results demonstrate that HPAEC undergo a pH-dependent loss of viability linked to active Na/H exchange following a metabolic insult. Potentiation of cell death with phorbol ester treatment suggests that this cell death pathway involves protein kinase C-mediated phosphorylation events.
MeSH term(s)	Antimetabolites/pharmacology ; Antimycin A/analogs & derivatives ; Antimycin A/pharmacology ; Cell Death/physiology ; Cells, Cultured ; Deoxyglucose/pharmacology ; Drug Combinations ; Endothelium, Vascular/cytology ; Endothelium, Vascular/drug effects ; Endothelium, Vascular/physiology ; Humans ; Hydrogen/metabolism ; Hydrogen-Ion Concentration ; Pulmonary Artery/cytology ; Pulmonary Artery/drug effects ; Pulmonary Artery/physiology ; Sodium-Hydrogen Exchangers/antagonists & inhibitors ; Sodium-Hydrogen Exchangers/physiology
Chemical Substances	Antimetabolites ; Drug Combinations ; Sodium-Hydrogen Exchangers ; antimycin (11118-72-2) ; Antimycin A (642-15-9) ; Hydrogen (7YNJ3PO35Z) ; Deoxyglucose (9G2MP84A8W)
Language	English
Publishing date	2000-03
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1013184-x
ISSN	1522-1504 ; 1040-0605
ISSN (online)	1522-1504
ISSN	1040-0605
DOI	10.1152/ajplung.2000.278.3.L536
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Article ; Online: Discovery of Gamma Rays from the Quiescent Sun with HAWC.

Albert, A / Alfaro, R / Alvarez, C / Arteaga-Velázquez, J C / Avila Rojas, D / Ayala Solares, H A / Babu, R / Belmont-Moreno, E / Brisbois, C / Caballero-Mora, K S / Capistrán, T / Carramiñana, A / Casanova, S / Chaparro-Amaro, O / Cotti, U / Cotzomi, J / Coutiño de León, S / De la Fuente, E / Diaz Hernandez, R /

Dingus, B L / DuVernois, M A / Durocher, M / Díaz-Vélez, J C / Ellsworth, R W / Engel, K / Espinoza, C / Fan, K L / Fang, K / Fernández Alonso, M / Fleischhack, H / Fraija, N / García-González, J A / Garfias, F / González, M M / Goodman, J A / Harding, J P / Hernandez, S / Hinton, J / Huang, D / Hueyotl-Zahuantitla, F / Hüntemeyer, P / Iriarte, A / Joshi, V / Kaufmann, S / Lee, J / Linnemann, J T / Longinotti, A L / Luis-Raya, G / Malone, K / Martinez, O / Martínez-Castro, J / Matthews, J A / Miranda-Romagnoli, P / Morales-Soto, J A / Moreno, E / Mostafá, M / Nayerhoda, A / Nellen, L / Nisa, M U / Noriega-Papaqui, R / Olivera-Nieto, L / Omodei, N / Pérez Araujo, Y / Pérez-Pérez, E G / Rho, C D / Rosa-González, D / Ruiz-Velasco, E / Salazar, H / Salazar-Gallegos, D / Sandoval, A / Schneider, M / Serna-Franco, J / Smith, A J / Son, Y / Springer, R W / Tibolla, O / Tollefson, K / Torres, I / Torres-Escobedo, R / Turner, R / Ureña-Mena, F / Varela, E / Villaseñor, L / Wang, X / Watson, I J / Willox, E / Yun-Cárcamo, S / Zhou, H / de León, C / Beacom, J F / Linden, T / Ng, K C Y / Peter, A H G / Zhou, B

Physical review letters

2023 Volume 131, Issue 5, Page(s) 51201

Abstract: We report the first detection of a TeV γ-ray flux from the solar disk (6.3σ), based on 6.1 years of data from the High Altitude Water Cherenkov (HAWC) observatory. The 0.5-2.6 TeV spectrum is well fit by a power law, dN/dE=A(E/1 TeV)^{-γ}, with A=(1.6±0. ...

Abstract	We report the first detection of a TeV γ-ray flux from the solar disk (6.3σ), based on 6.1 years of data from the High Altitude Water Cherenkov (HAWC) observatory. The 0.5-2.6 TeV spectrum is well fit by a power law, dN/dE=A(E/1 TeV)^{-γ}, with A=(1.6±0.3)×10^{-12} TeV^{-1} cm^{-2} s^{-1} and γ=3.62±0.14. The flux shows a strong indication of anticorrelation with solar activity. These results extend the bright, hard GeV emission from the disk observed with Fermi-LAT, seemingly due to hadronic Galactic cosmic rays showering on nuclei in the solar atmosphere. However, current theoretical models are unable to explain the details of how solar magnetic fields shape these interactions. HAWC's TeV detection thus deepens the mysteries of the solar-disk emission.
Language	English
Publishing date	2023-08-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.131.051201
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Book: Potlatch and stratification among the Tlingit

Tollefson, Kenneth

(Abhandlungen der Völkerkundlichen Arbeitsgemeinschaft ; 42)

1985

Institution	Völkerkundliche Arbeitsgemeinschaft
Author's details	Kenneth Tollefson
Series title	Abhandlungen der Völkerkundlichen Arbeitsgemeinschaft ; 42
Language	English
Size	15 S
Publishing place	Nortorf
Document type	Book
Database	Former special subject collection: coastal and deep sea fishing

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Article ; Online: Constraints on Lorentz Invariance Violation from HAWC Observations of Gamma Rays above 100 TeV.

Albert, A / Alfaro, R / Alvarez, C / Angeles Camacho, J R / Arteaga-Velázquez, J C / Arunbabu, K P / Avila Rojas, D / Ayala Solares, H A / Baghmanyan, V / Belmont-Moreno, E / BenZvi, S Y / Brisbois, C / Caballero-Mora, K S / Capistrán, T / Carramiñana, A / Casanova, S / Cotti, U / Cotzomi, J / Coutiño de León, S /

De la Fuente, E / de León, C / Dingus, B L / DuVernois, M A / Díaz-Vélez, J C / Ellsworth, R W / Engel, K / Espinoza, C / Fleischhack, H / Fraija, N / Galván-Gámez, A / Garcia, D / García-González, J A / Garfias, F / González, M M / Goodman, J A / Harding, J P / Hernandez, S / Hona, B / Huang, D / Hueyotl-Zahuantitla, F / Hüntemeyer, P / Iriarte, A / Joshi, V / Lara, A / Lee, W H / León Vargas, H / Linnemann, J T / Longinotti, A L / Luis-Raya, G / Lundeen, J / López-Coto, R / Malone, K / Marinelli, S S / Martinez-Castellanos, I / Martínez-Castro, J / Martínez-Huerta, H / Matthews, J A / Miranda-Romagnoli, P / Morales-Soto, J A / Moreno, E / Nayerhoda, A / Nellen, L / Newbold, M / Nisa, M U / Noriega-Papaqui, R / Omodei, N / Peisker, A / Pérez-Pérez, E G / Rho, C D / Rivière, C / Rosa-González, D / Rosenberg, M / Ruiz-Velasco, E / Salazar, H / Salesa Greus, F / Sandoval, A / Schneider, M / Schoorlemmer, H / Sinnis, G / Smith, A J / Springer, R W / Surajbali, P / Tabachnick, E / Tanner, M / Tibolla, O / Tollefson, K / Torres, I / Torres-Escobedo, R / Weisgarber, T / Yodh, G / Zepeda, A / Zhou, H

Physical review letters

2020 Volume 124, Issue 13, Page(s) 131101

Abstract: Because of the high energies and long distances to the sources, astrophysical observations provide a unique opportunity to test possible signatures of Lorentz invariance violation (LIV). Superluminal LIV enables the decay of photons at high energy. The ... ...

Abstract	Because of the high energies and long distances to the sources, astrophysical observations provide a unique opportunity to test possible signatures of Lorentz invariance violation (LIV). Superluminal LIV enables the decay of photons at high energy. The high altitude water Cherenkov (HAWC) observatory is among the most sensitive gamma-ray instruments currently operating above 10 TeV. HAWC finds evidence of 100 TeV photon emission from at least four astrophysical sources. These observations exclude, for the strongest of the limits set, the LIV energy scale to 2.2×10^{31} eV, over 1800 times the Planck energy and an improvement of 1 to 2 orders of magnitude over previous limits.
Language	English
Publishing date	2020-04-17
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.124.131101
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Article ; Online: Multiple Galactic Sources with Emission Above 56 TeV Detected by HAWC.

Abeysekara, A U / Albert, A / Alfaro, R / Angeles Camacho, J R / Arteaga-Velázquez, J C / Arunbabu, K P / Avila Rojas, D / Ayala Solares, H A / Baghmanyan, V / Belmont-Moreno, E / BenZvi, S Y / Brisbois, C / Caballero-Mora, K S / Capistrán, T / Carramiñana, A / Casanova, S / Cotti, U / Cotzomi, J / Coutiño de León, S /

De la Fuente, E / de León, C / Dichiara, S / Dingus, B L / DuVernois, M A / Díaz-Vélez, J C / Ellsworth, R W / Engel, K / Espinoza, C / Fleischhack, H / Fraija, N / Galván-Gámez, A / Garcia, D / García-González, J A / Garfias, F / González, M M / Goodman, J A / Harding, J P / Hernandez, S / Hinton, J / Hona, B / Huang, D / Hueyotl-Zahuantitla, F / Hüntemeyer, P / Iriarte, A / Jardin-Blicq, A / Joshi, V / Kaufmann, S / Kieda, D / Lara, A / Lee, W H / León Vargas, H / Linnemann, J T / Longinotti, A L / Luis-Raya, G / Lundeen, J / López-Coto, R / Malone, K / Marinelli, S S / Martinez, O / Martinez-Castellanos, I / Martínez-Castro, J / Martínez-Huerta, H / Matthews, J A / Miranda-Romagnoli, P / Morales-Soto, J A / Moreno, E / Mostafá, M / Nayerhoda, A / Nellen, L / Newbold, M / Nisa, M U / Noriega-Papaqui, R / Peisker, A / Pérez-Pérez, E G / Pretz, J / Ren, Z / Rho, C D / Rivière, C / Rosa-González, D / Rosenberg, M / Ruiz-Velasco, E / Salesa Greus, F / Sandoval, A / Schneider, M / Schoorlemmer, H / Sinnis, G / Smith, A J / Springer, R W / Surajbali, P / Tabachnick, E / Tanner, M / Tibolla, O / Tollefson, K / Torres, I / Torres-Escobedo, R / Villaseñor, L / Weisgarber, T / Wood, J / Yapici, T / Zhang, H / Zhou, H

Physical review letters

2020 Volume 124, Issue 2, Page(s) 21102

Abstract: We present the first catalog of gamma-ray sources emitting above 56 and 100 TeV with data from the High Altitude Water Cherenkov Observatory, a wide field-of-view observatory capable of detecting gamma rays up to a few hundred TeV. Nine sources are ... ...

Abstract	We present the first catalog of gamma-ray sources emitting above 56 and 100 TeV with data from the High Altitude Water Cherenkov Observatory, a wide field-of-view observatory capable of detecting gamma rays up to a few hundred TeV. Nine sources are observed above 56 TeV, all of which are likely galactic in origin. Three sources continue emitting past 100 TeV, making this the highest-energy gamma-ray source catalog to date. We report the integral flux of each of these objects. We also report spectra for three highest-energy sources and discuss the possibility that they are PeVatrons.
Language	English
Publishing date	2020-02-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	208853-8
ISSN	1079-7114 ; 0031-9007
ISSN (online)	1079-7114
ISSN	0031-9007
DOI	10.1103/PhysRevLett.124.021102
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Article ; Online: Observation of high-energy neutrinos from the Galactic plane.

Abbasi, R / Ackermann, M / Adams, J / Aguilar, J A / Ahlers, M / Ahrens, M / Alameddine, J M / Alves, A A / Amin, N M / Andeen, K / Anderson, T / Anton, G / Argüelles, C / Ashida, Y / Athanasiadou, S / Axani, S / Bai, X / Balagopal V, A / Barwick, S W /

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Science (New York, N.Y.)

2023 Volume 380, Issue 6652, Page(s) 1338–1343

Abstract: The origin of high-energy cosmic rays, atomic nuclei that continuously impact Earth's atmosphere, is unknown. Because of deflection by interstellar magnetic fields, cosmic rays produced within the Milky Way arrive at Earth from random directions. However, ...

Abstract	The origin of high-energy cosmic rays, atomic nuclei that continuously impact Earth's atmosphere, is unknown. Because of deflection by interstellar magnetic fields, cosmic rays produced within the Milky Way arrive at Earth from random directions. However, cosmic rays interact with matter near their sources and during propagation, which produces high-energy neutrinos. We searched for neutrino emission using machine learning techniques applied to 10 years of data from the IceCube Neutrino Observatory. By comparing diffuse emission models to a background-only hypothesis, we identified neutrino emission from the Galactic plane at the 4.5σ level of significance. The signal is consistent with diffuse emission of neutrinos from the Milky Way but could also arise from a population of unresolved point sources.
Language	English
Publishing date	2023-06-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	128410-1
ISSN	1095-9203 ; 0036-8075
ISSN (online)	1095-9203
ISSN	0036-8075
DOI	10.1126/science.adc9818
Database	MEDical Literature Analysis and Retrieval System OnLINE

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