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  1. Article: Print-Light-Synthesis for Single-Step Metal Nanoparticle Synthesis and Patterned Electrode Production.

    Gianvittorio, Stefano / Tonelli, Domenica / Lesch, Andreas

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 13

    Abstract: The fabrication of thin-film electrodes, which contain metal nanoparticles and nanostructures for applications in electrochemical sensing as well as energy conversion and storage, is often based on multi-step procedures that include two main passages: (i) ...

    Abstract The fabrication of thin-film electrodes, which contain metal nanoparticles and nanostructures for applications in electrochemical sensing as well as energy conversion and storage, is often based on multi-step procedures that include two main passages: (i) the synthesis and purification of nanomaterials and (ii) the fabrication of thin films by coating electrode supports with these nanomaterials. The patterning and miniaturization of thin film electrodes generally require masks or advanced patterning instrumentation. In recent years, various approaches have been presented to integrate the spatially resolved deposition of metal precursor solutions and the rapid conversion of the precursors into metal nanoparticles. To achieve the latter, high intensity light irradiation has, in particular, become suitable as it enables the photochemical, photocatalytical, and photothermal conversion of the precursors during or slightly after the precursor deposition. The conversion of the metal precursors directly on the target substrates can make the use of capping and stabilizing agents obsolete. This review focuses on hybrid platforms that comprise digital metal precursor ink printing and high intensity light irradiation for inducing metal precursor conversions into patterned metal and alloy nanoparticles. The combination of the two methods has recently been named Print-Light-Synthesis by a group of collaborators and is characterized by its sustainability in terms of low material consumption, low material waste, and reduced synthesis steps. It provides high control of precursor loading and light irradiation, both affecting and improving the fabrication of thin film electrodes.
    Language English
    Publishing date 2023-06-23
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13131915
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: ALP-Based Biosensors Employing Electrodes Modified with Carbon Nanomaterials for Pesticides Detection.

    Gianvittorio, Stefano / Gualandi, Isacco / Tonelli, Domenica

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 4

    Abstract: Due to the growing presence of pesticides in the environment and in food, the concern of their impact on human health is increasing. Therefore, the development of fast and reliable detection methods is needed. Enzymatic inhibition-based biosensors ... ...

    Abstract Due to the growing presence of pesticides in the environment and in food, the concern of their impact on human health is increasing. Therefore, the development of fast and reliable detection methods is needed. Enzymatic inhibition-based biosensors represent a good alternative for replacing the more complicated and time-consuming traditional methods (chromatography, spectrophotometry, etc.). This paper describes the development of an electrochemical biosensor exploiting alkaline phosphatase as the biological recognition element and a chemically modified glassy carbon electrode as the transducer. The biosensor was prepared modifying the GCE surface by a mixture of Multi-Walled-Carbon-Nanotubes (MWCNTs) and Electrochemically-Reduced-Graphene-Oxide (ERGO) followed by the immobilization of the enzyme by cross-linking with bovine serum albumin and glutaraldehyde. The inhibition of the biosensor response caused by pesticides was established using 2-phospho-L-ascorbic acid as the enzymatic substrate, whose dephosphorylation reaction produces ascorbic acid (AA). The MWCNTs/ERGO mixture shows a synergic effect in terms of increased sensitivity and decreased overpotential for AA oxidation. The response of the biosensor to the herbicide 2,4-dichloro-phenoxy-acetic-acid was evaluated and resulted in the concentration range 0.04-24 nM, with a limit of the detection of 16 pM. The determination of other pesticides was also achieved. The re-usability of the electrode was demonstrated by performing a washing procedure.
    MeSH term(s) Alkaline Phosphatase ; Biosensing Techniques/methods ; Carbon/chemistry ; Electrochemical Techniques/methods ; Electrodes ; Nanotubes, Carbon/chemistry ; Pesticides/chemistry
    Chemical Substances Alkaline Phosphatase (EC 3.1.3.1) ; Carbon (7440-44-0) ; graphene oxide ; Nanotubes, Carbon ; Pesticides
    Language English
    Publishing date 2023-02-05
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28041532
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Synthesis of TiO

    Luo, Wenpo / Blanchard, Juliette / Tonelli, Domenica / Taleb, Abdelhafed

    Micromachines

    2023  Volume 14, Issue 2

    Abstract: ... ...

    Abstract TiO
    Language English
    Publishing date 2023-01-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2620864-7
    ISSN 2072-666X
    ISSN 2072-666X
    DOI 10.3390/mi14020243
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Focus Review on Nanomaterial-Based Electrochemical Sensing of Glucose for Health Applications.

    Tonelli, Domenica / Gualandi, Isacco / Scavetta, Erika / Mariani, Federica

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 12

    Abstract: Diabetes management can be considered the first paradigm of modern personalized medicine. An overview of the most relevant advancements in glucose sensing achieved in the last 5 years is presented. In particular, devices exploiting both consolidated and ... ...

    Abstract Diabetes management can be considered the first paradigm of modern personalized medicine. An overview of the most relevant advancements in glucose sensing achieved in the last 5 years is presented. In particular, devices exploiting both consolidated and innovative electrochemical sensing strategies, based on nanomaterials, have been described, taking into account their performances, advantages and limitations, when applied for the glucose analysis in blood and serum samples, urine, as well as in less conventional biological fluids. The routine measurement is still largely based on the finger-pricking method, which is usually considered unpleasant. In alternative, glucose continuous monitoring relies on electrochemical sensing in the interstitial fluid, using implanted electrodes. Due to the invasive nature of such devices, further investigations have been carried out in order to develop less invasive sensors that can operate in sweat, tears or wound exudates. Thanks to their unique features, nanomaterials have been successfully applied for the development of both enzymatic and non-enzymatic glucose sensors, which are compliant with the specific needs of the most advanced applications, such as flexible and deformable systems capable of conforming to skin or eyes, in order to produce reliable medical devices operating at the point of care.
    Language English
    Publishing date 2023-06-19
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13121883
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  5. Article: From Traditional to New Benchmark Catalysts for CO

    Serafini, Martina / Mariani, Federica / Basile, Francesco / Scavetta, Erika / Tonelli, Domenica

    Nanomaterials (Basel, Switzerland)

    2023  Volume 13, Issue 11

    Abstract: In the last century, conventional strategies pursued to reduce or convert ... ...

    Abstract In the last century, conventional strategies pursued to reduce or convert CO
    Language English
    Publishing date 2023-05-24
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano13111723
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  6. Article ; Online: Ontogeny of the circadian system: a multiscale process throughout development.

    Comas, Maria / De Pietri Tonelli, Davide / Berdondini, Luca / Astiz, Mariana

    Trends in neurosciences

    2023  Volume 47, Issue 1, Page(s) 36–46

    Abstract: The 24 h (circadian) timing system develops in mammals during the perinatal period. It carries out the essential task of anticipating daily recurring environmental changes to identify the best time of day for each molecular, cellular, and systemic ... ...

    Abstract The 24 h (circadian) timing system develops in mammals during the perinatal period. It carries out the essential task of anticipating daily recurring environmental changes to identify the best time of day for each molecular, cellular, and systemic process. Although significant knowledge has been acquired about the organization and function of the adult circadian system, relatively little is known about its ontogeny. During the perinatal period, the circadian system progressively gains functionality under the influence of the early environment. This review explores current evidence on the development of the circadian clock in mammals, highlighting the multilevel complexity of the process and the importance of gaining a better understanding of its underlying biology.
    MeSH term(s) Humans ; Animals ; Pregnancy ; Female ; Circadian Rhythm ; Suprachiasmatic Nucleus ; Circadian Clocks ; Mammals
    Language English
    Publishing date 2023-12-08
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 282488-7
    ISSN 1878-108X ; 0378-5912 ; 0166-2236
    ISSN (online) 1878-108X
    ISSN 0378-5912 ; 0166-2236
    DOI 10.1016/j.tins.2023.11.004
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  7. Article: Synthesis and Characterization of Layered Double Hydroxides as Materials for Electrocatalytic Applications.

    Tonelli, Domenica / Gualandi, Isacco / Musella, Elisa / Scavetta, Erika

    Nanomaterials (Basel, Switzerland)

    2021  Volume 11, Issue 3

    Abstract: Layered double hydroxides (LDHs) are anionic clays which have found applications in a wide range of fields, including electrochemistry. In such a case, to display good performances they should possess electrical conductivity which can be ensured by the ... ...

    Abstract Layered double hydroxides (LDHs) are anionic clays which have found applications in a wide range of fields, including electrochemistry. In such a case, to display good performances they should possess electrical conductivity which can be ensured by the presence of metals able to give reversible redox reactions in a proper potential window. The metal centers can act as redox mediators to catalyze reactions for which the required overpotential is too high, and this is a key aspect for the development of processes and devices where the control of charge transfer reactions plays an important role. In order to act as redox mediator, a material can be present in solution or supported on a conductive support. The most commonly used methods to synthesize LDHs, referring both to bulk synthesis and in situ growth methods, which allow for the direct modification of conductive supports, are here summarized. In addition, the most widely used techniques to characterize the LDHs structure and morphology are also reported, since their electrochemical performance is strictly related to these features. Finally, some electrocatalytic applications of LDHs, when synthesized as nanomaterials, are discussed considering those related to sensing, oxygen evolution reaction, and other energy issues.
    Language English
    Publishing date 2021-03-13
    Publishing country Switzerland
    Document type Journal Article ; Review
    ZDB-ID 2662255-5
    ISSN 2079-4991
    ISSN 2079-4991
    DOI 10.3390/nano11030725
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  8. Article ; Online: Global land and water limits to electrolytic hydrogen production using wind and solar resources.

    Tonelli, Davide / Rosa, Lorenzo / Gabrielli, Paolo / Caldeira, Ken / Parente, Alessandro / Contino, Francesco

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 5532

    Abstract: Proposals for achieving net-zero emissions by 2050 include scaling-up electrolytic hydrogen production, however, this poses technical, economic, and environmental challenges. One such challenge is for policymakers to ensure a sustainable future for the ... ...

    Abstract Proposals for achieving net-zero emissions by 2050 include scaling-up electrolytic hydrogen production, however, this poses technical, economic, and environmental challenges. One such challenge is for policymakers to ensure a sustainable future for the environment including freshwater and land resources while facilitating low-carbon hydrogen production using renewable wind and solar energy. We establish a country-by-country reference scenario for hydrogen demand in 2050 and compare it with land and water availability. Our analysis highlights countries that will be constrained by domestic natural resources to achieve electrolytic hydrogen self-sufficiency in a net-zero target. Depending on land allocation for the installation of solar panels or wind turbines, less than 50% of hydrogen demand in 2050 could be met through a local production without land or water scarcity. Our findings identify potential importers and exporters of hydrogen or, conversely, exporters or importers of industries that would rely on electrolytic hydrogen. The abundance of land and water resources in Southern and Central-East Africa, West Africa, South America, Canada, and Australia make these countries potential leaders in hydrogen export.
    Language English
    Publishing date 2023-09-08
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-41107-x
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  9. Article ; Online: Evaluation of the Antioxidant Capacity of Fruit Juices by Two Original Analytical Methods.

    Protti, Michele / Gualandi, Isacco / Zappoli, Sergio / Mandrioli, Roberto / Mercolini, Laura / Tonelli, Domenica

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 18

    Abstract: Two analytical methods previously developed by our groups were employed to estimate the antioxidant capacity of commercial fruit juices. The electrochemical method, which measures the scavenging activity of antioxidants towards OH radicals generated by ... ...

    Abstract Two analytical methods previously developed by our groups were employed to estimate the antioxidant capacity of commercial fruit juices. The electrochemical method, which measures the scavenging activity of antioxidants towards OH radicals generated by both hydrogen peroxide photolysis and Fenton's reaction, is based on the recovery of the cyclic voltametric response of the redox probe Ru(NH
    MeSH term(s) Antioxidants/chemistry ; Fruit and Vegetable Juices/analysis ; Hydroxyl Radical/chemistry ; Oxidation-Reduction ; Hydrogen Peroxide/chemistry ; Fruit/chemistry
    Chemical Substances Antioxidants ; Hydroxyl Radical (3352-57-6) ; Hydrogen Peroxide (BBX060AN9V)
    Language English
    Publishing date 2023-09-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28186672
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  10. Article: Porosity of a Fast-Setting Mortar with Crystallization Admixture and Effect of a SA-PA Modification.

    Cotini, Oscar / Di Maggio, Rosa / Tonelli, Daniel / Nascimben, Roger / Ataollahi, Narges

    Materials (Basel, Switzerland)

    2022  Volume 15, Issue 4

    Abstract: Air permeability measurements according to the Hagen-Poiseuille equation, Scanning Electron Microscopy (SEM) and mercury intrusion porosimetry (MIP) tests were conducted on samples of cementitious mortar at different curing times to study the correlation ...

    Abstract Air permeability measurements according to the Hagen-Poiseuille equation, Scanning Electron Microscopy (SEM) and mercury intrusion porosimetry (MIP) tests were conducted on samples of cementitious mortar at different curing times to study the correlation between the increased crystallization and their microstructure. The mortar samples were prepared with a commercial fast-setting premix containing calcium silicates and quartz. The average permeability coefficient (K) was 2.96 × 10
    Language English
    Publishing date 2022-02-18
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2487261-1
    ISSN 1996-1944
    ISSN 1996-1944
    DOI 10.3390/ma15041542
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