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  1. Article ; Online: Para-Hisian Atrial Tachycardia and Atrioventricular Nodal Reentry Tachycardia: After 25 Years The Same History?

    Toniolo, Mauro

    Arquivos brasileiros de cardiologia

    2021  Volume 116, Issue 1, Page(s) 127–128

    Title translation Taquicardia Atrial Para-Hissiana e Taquicardia de Reentrada Nodal Atrioventricular: 25 Anos Depois, a Mesma História?
    MeSH term(s) Bundle of His ; Catheter Ablation ; Humans ; Tachycardia, Atrioventricular Nodal Reentry/diagnosis ; Tachycardia, Supraventricular/diagnosis
    Language Portuguese
    Publishing date 2021-03-11
    Publishing country Brazil
    Document type Editorial ; Comment
    ZDB-ID 730261-7
    ISSN 1678-4170 ; 0066-782X
    ISSN (online) 1678-4170
    ISSN 0066-782X
    DOI 10.36660/abc.20201149
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Catheter ablation of arrhythmias in some European countries: Toy or tool?

    Toniolo, Mauro

    Pacing and clinical electrophysiology : PACE

    2021  Volume 44, Issue 2, Page(s) 408–409

    Abstract: In the last decades, catheter ablation of arrhythmias is rapidly evolving in Europe. Despite the high number of procedures performed, in some European countries, both the organization of the electrophysiology labs and the training of clinical ... ...

    Abstract In the last decades, catheter ablation of arrhythmias is rapidly evolving in Europe. Despite the high number of procedures performed, in some European countries, both the organization of the electrophysiology labs and the training of clinical electrophysiologists are still not completely effective and not in line with the standard recommendations of National Electrophysiology Societies. For these reasons, it is probably desirable for arrhythmia sections to become independent units in order to assure high quality and safety standards.
    MeSH term(s) Arrhythmias, Cardiac/surgery ; Catheter Ablation/trends ; Europe ; Humans
    Language English
    Publishing date 2021-01-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14148
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Pacing maneuvers from the aortic cusps: A useful technique during ablation of focal arrhythmias arising from the aortic root.

    Toniolo, Mauro / Taurian, Marco / Rebellato, Luca / Daleffe, Elisabetta / Muser, Daniele

    Pacing and clinical electrophysiology : PACE

    2023  Volume 46, Issue 5, Page(s) 353–357

    Abstract: Background: The ablation of arrhythmias arising near the His-bundle region in the non-coronary aortic cusp (NCAC) is challenging. Among the aortic sinuses of Valsalva, the NCAC is located between the right atrium and the left atrium. For this reason, ... ...

    Abstract Background: The ablation of arrhythmias arising near the His-bundle region in the non-coronary aortic cusp (NCAC) is challenging. Among the aortic sinuses of Valsalva, the NCAC is located between the right atrium and the left atrium. For this reason, pacing from the NCAC should result in atrial capture while pacing from the right and left coronary cusps (LCC) may result in ventricular capture. The objective of this study is to prove that atrial capture during pacing from the sinuses of Valsalva may be used to confirm a correct position in the non-coronary cusp.
    Methods: A total of 30 patients with structurally normal heart undergoing left sided ablation procedures, underwent electrophysiological study of the aortic cusps. Each of the aortic valve cusps was paced with increasing outputs and analyzed offline to determine their unique electrocardiographic characteristics.
    Results: In the NCAC, we obtained an atrial capture in 29 out of 30 patients (96.6%). The atrial capture was highly specific for a position in the NCAC (p < .001). The median output required to capture from the cusp was 10 mA (range 5-25 mA) at a pulse width of 2 ms. In the right coronary cusp (RCC) and LCC, we obtained ventricular capture in all patients (100%). The median output required to capture from the cusp was 10 mA (range 10-25 mA) in RCC and 25 mA (range 10-25 mA) in LCC at a pulse width of 2 ms.
    Conclusions: Atrial capture during a pacemapping from the aortic cusps can be considered proof of a correct position in NCAC.
    MeSH term(s) Humans ; Aorta, Thoracic ; Atrial Fibrillation ; Carcinoma, Renal Cell ; Aorta/surgery ; Electrocardiography ; Kidney Neoplasms ; Catheter Ablation/methods
    Language English
    Publishing date 2023-04-04
    Publishing country United States
    Document type Journal Article
    ZDB-ID 424437-0
    ISSN 1540-8159 ; 0147-8389
    ISSN (online) 1540-8159
    ISSN 0147-8389
    DOI 10.1111/pace.14694
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Unpredictable Fall of Severe Emergent Cardiovascular Diseases Hospital Admissions During the COVID-19 Pandemic: Experience of a Single Large Center in Northern Italy.

    Toniolo, Mauro / Negri, Francesco / Antonutti, Marco / Masè, Marco / Facchin, Domenico

    Journal of the American Heart Association

    2020  Volume 9, Issue 13, Page(s) e017122

    Abstract: Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic in Europe. The impact of the pandemic and the consequent lockdown on medical emergencies other than those SARS-CoV 2 pandemic ... ...

    Abstract Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic in Europe. The impact of the pandemic and the consequent lockdown on medical emergencies other than those SARS-CoV 2 pandemic related is largely unknown. The aim of this study was to analyze the epidemiologic impact of coronavirus disease 2019 pandemic on hospital admission for severe emergent cardiovascular diseases (SECDs) in a single Northern Italy large tertiary referral center. Methods and Results We quantified SECDs admissions to the Cardiology Division of Udine University Hospital between March 1, 2020 and March 31, 2020 and compared them with those of the same time frame during 2019. Compared with March 2019, we observed a significant reduction in all SECDs admissions: -30% for ST-segment-elevation acute coronary syndromes, -66% for non-ST-segment-elevation acute coronary syndromes and -50% for severe bradyarrhythmia. Conclusions A significant decrease in all SECDs admissions has been observed during the SARS-CoV 2. pandemic and was unlikely caused by a reduction in the incidence of cardiovascular diseases. Fear of contagion may have contributed to the unpredictable drop of SECDs. Social education about early recognition of symptoms of life-threatening cardiac conditions requiring appropriate care in a timely fashion may help to reduce this counterproductive phenomenon.
    MeSH term(s) Aged ; Betacoronavirus ; COVID-19 ; Cardiovascular Diseases/etiology ; Coronavirus Infections/complications ; Coronavirus Infections/epidemiology ; Emergencies ; Emergency Service, Hospital/statistics & numerical data ; Female ; Follow-Up Studies ; Humans ; Incidence ; Italy/epidemiology ; Male ; Middle Aged ; Pandemics ; Patient Admission/trends ; Pneumonia, Viral/complications ; Pneumonia, Viral/epidemiology ; Retrospective Studies ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-05-22
    Publishing country England
    Document type Comparative Study ; Journal Article
    ZDB-ID 2653953-6
    ISSN 2047-9980 ; 2047-9980
    ISSN (online) 2047-9980
    ISSN 2047-9980
    DOI 10.1161/JAHA.120.017122
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Unpredictable Fall of Severe Emergent Cardiovascular Diseases Hospital Admissions During the COVID‐19 Pandemic

    Toniolo, Mauro / Negri, Francesco / Antonutti, Marco / Masè, Marco / Facchin, Domenico

    Journal of the American Heart Association

    Experience of a Single Large Center in Northern Italy

    2020  Volume 9, Issue 13

    Abstract: Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV 2) pandemic in Europe. The impact of the pandemic and the consequent lockdown on medical emergencies other than those SARS‐CoV 2 pandemic ... ...

    Abstract Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS‐CoV 2) pandemic in Europe. The impact of the pandemic and the consequent lockdown on medical emergencies other than those SARS‐CoV 2 pandemic related is largely unknown. The aim of this study was to analyze the epidemiologic impact of coronavirus disease 2019 pandemic on hospital admission for severe emergent cardiovascular diseases ( SECD s) in a single Northern Italy large tertiary referral center. Methods and Results We quantified SECD s admissions to the Cardiology Division of Udine University Hospital between March 1, 2020 and March 31, 2020 and compared them with those of the same time frame during 2019. Compared with March 2019, we observed a significant reduction in all SECD s admissions: −30% for ST ‐segment–elevation acute coronary syndromes, −66% for non‐ ST ‐segment–elevation acute coronary syndromes and −50% for severe bradyarrhythmia. Conclusions A significant decrease in all SECD s admissions has been observed during the SARS‐CoV 2. pandemic and was unlikely caused by a reduction in the incidence of cardiovascular diseases. Fear of contagion may have contributed to the unpredictable drop of SECD s. Social education about early recognition of symptoms of life‐threatening cardiac conditions requiring appropriate care in a timely fashion may help to reduce this counterproductive phenomenon.
    Keywords Cardiology and Cardiovascular Medicine ; covid19
    Language English
    Publisher Ovid Technologies (Wolters Kluwer Health)
    Publishing country us
    Document type Article ; Online
    ZDB-ID 2653953-6
    ISSN 2047-9980
    ISSN 2047-9980
    DOI 10.1161/jaha.120.017122
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  6. Article: Unpredictable Fall of Severe Emergent Cardiovascular Diseases Hospital Admissions During the COVID-19 Pandemic: Experience of a Single Large Center in Northern Italy

    Toniolo, Mauro / Negri, Francesco / Antonutti, Marco / Masè, Marco / Facchin, Domenico

    J Am Heart Assoc

    Abstract: Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic in Europe. The impact of the pandemic and the consequent lockdown on medical emergencies other than those SARS-CoV 2 pandemic ... ...

    Abstract Background Northern Italy is one of the epicenters of severe acute respiratory syndrome coronavirus 2 (SARS-CoV 2) pandemic in Europe. The impact of the pandemic and the consequent lockdown on medical emergencies other than those SARS-CoV 2 pandemic related is largely unknown. The aim of this study was to analyze the epidemiologic impact of coronavirus disease 2019 pandemic on hospital admission for severe emergent cardiovascular diseases (SECDs) in a single Northern Italy large tertiary referral center. Methods and Results We quantified SECDs admissions to the Cardiology Division of Udine University Hospital between March 1, 2020 and March 31, 2020 and compared them with those of the same time frame during 2019. Compared with March 2019, we observed a significant reduction in all SECDs admissions: -30% for ST-segment-elevation acute coronary syndromes, -66% for non-ST-segment-elevation acute coronary syndromes and -50% for severe bradyarrhythmia. Conclusions A significant decrease in all SECDs admissions has been observed during the SARS-CoV 2. pandemic and was unlikely caused by a reduction in the incidence of cardiovascular diseases. Fear of contagion may have contributed to the unpredictable drop of SECDs. Social education about early recognition of symptoms of life-threatening cardiac conditions requiring appropriate care in a timely fashion may help to reduce this counterproductive phenomenon.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #342792
    Database COVID19

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  7. Article ; Online: Oral procainamide as pharmacological treatment of recurrent and refractory ventricular tachyarrhythmias: A single-center experience.

    Toniolo, Mauro / Muser, Daniele / Grilli, Giulia / Burelli, Massimo / Rebellato, Luca / Daleffe, Elisabetta / Facchin, Domenico / Imazio, Massimo

    Heart rhythm O2

    2021  Volume 2, Issue 6Part B, Page(s) 840–847

    Abstract: Background: Antiarrhythmic therapy for recurrent ventricular arrhythmias in patients who have undergone catheter ablation, and in whom amiodarone and/or beta-blockers were ineffective or contraindicated, is a controversial issue.: Objective: The ... ...

    Abstract Background: Antiarrhythmic therapy for recurrent ventricular arrhythmias in patients who have undergone catheter ablation, and in whom amiodarone and/or beta-blockers were ineffective or contraindicated, is a controversial issue.
    Objective: The present study sought to evaluate the efficacy and tolerability of oral procainamide in patients with recurrent ventricular arrhythmias when the standard therapy strategy had failed.
    Methods: All patients treated with procainamide for recurrent ventricular tachycardia (VT) or ventricular fibrillation (VF) in our institution between January 2010 and May 2019 were enrolled. The primary endpoint was the total number of implantable cardioverter-defibrillator (ICD) interventions after the beginning of procainamide therapy. Secondary endpoints were the total number of VTs and VFs recorded on the ICDs' controls and discontinuation of therapy. The events occurring during procainamide treatment were compared with a matched-duration period before the initiation of therapy with procainamide. Patients therefore served as self-controls.
    Results: A total of 34 consecutive patients (32 male, 94.1%; mean age 74.4 ± 9.7 years) were included in the retrospective analysis. The mean time of procainamide treatment was 12.9 ± 13.7 months (median 9 [2-20] months). The mean dose of procainamide was 1207 ± 487 mg/day. Procainamide therapy significantly decreased ICD interventions (median 5 [0-22.5] vs 15.5 [3-32.25],
    Conclusion: Oral procainamide was associated with a significant decrease in ICD therapies and ventricular arrhythmias, showing an acceptable profile of tolerability.
    Language English
    Publishing date 2021-12-17
    Publishing country United States
    Document type Journal Article
    ISSN 2666-5018
    ISSN (online) 2666-5018
    DOI 10.1016/j.hroo.2021.10.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: Efficacy and Safety of Catheter Ablation of Atrial Tachycardia Through a Direct Approach from Noncoronary Sinus of Valsalva.

    Toniolo, Mauro / Rebellato, Luca / Poli, Stefano / Daleffe, Elisabetta / Proclemer, Alessandro

    The American journal of cardiology

    2016  Volume 118, Issue 12, Page(s) 1847–1854

    Abstract: Noncoronary aortic cusp (NCAC) in the aorta represents a challenging location for catheter ablation of focal atrial tachycardias (ATs) arising near the His-bundle region. The purpose of this study was to provide an updated report on the methods, efficacy, ...

    Abstract Noncoronary aortic cusp (NCAC) in the aorta represents a challenging location for catheter ablation of focal atrial tachycardias (ATs) arising near the His-bundle region. The purpose of this study was to provide an updated report on the methods, efficacy, and safety of catheter ablation of ATs originating from NCAC. The study population includes 23 patients (18 women [78%], mean age 65 ± 12 years) with highly symptomatic AT. The atrial mapping was performed during tachycardia to define the earliest atrial activation site. Electrophysiological mapping of the right atrium was initially performed, followed by aortic root mapping when earliest activation was recorded in the proximal electrode of the His-bundle catheter. A direct ablation approach from NCAC was used in every patient independently by the local activation time. Ablations were performed using a steerable 4-mm tip nonirrigated catheter in all patients. Radiofrequency energy resulted in the disappearance of arrhythmias in 22 of the 23 patients (95%). In all procedures, there were no complications. During a mean follow-up of 41 ± 25 months, no patient presented with a recurrence, except the 1 patient where the ablation was not effective. In conclusion, catheter ablation of para-hisian ATs through a direct approach from NCAC shows to be safe and effective after 1 procedure per patient.
    MeSH term(s) Aged ; Aorta ; Bundle of His ; Catheter Ablation/methods ; Female ; Humans ; Male ; Middle Aged ; Sinus of Valsalva/surgery ; Tachycardia, Ectopic Atrial/surgery
    Language English
    Publishing date 2016-12-15
    Publishing country United States
    Document type Journal Article
    ZDB-ID 80014-4
    ISSN 1879-1913 ; 0002-9149
    ISSN (online) 1879-1913
    ISSN 0002-9149
    DOI 10.1016/j.amjcard.2016.08.076
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Induction of tachycardia confined within a pulmonary vein by electrical cardioversion of atrial fibrillation: Is it proof of reentry?

    Toniolo, Mauro / Figueroa, Jorge / Castrejòn-Castrejòn, Sergio / Merino, Jose Luis

    HeartRhythm case reports

    2015  Volume 1, Issue 4, Page(s) 225–228

    Language English
    Publishing date 2015-04-02
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2834871-0
    ISSN 2214-0271
    ISSN 2214-0271
    DOI 10.1016/j.hrcr.2015.03.009
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article ; Online: Revolving thrombus within the left atrium at atrial fibrillation ablation.

    Toniolo, Mauro / Estrada, Alejandro / Filgueiras-Rama, David / Merino, Josè L

    Herzschrittmachertherapie & Elektrophysiologie

    2015  Volume 26, Issue 1, Page(s) 54–55

    Abstract: A 68-year-old man was referred for pulmonary vein (PV) isolation. Access to the left atrium was obtained via a single transseptal puncture. A heparin bolus was given immediately after puncture. Angiography of the left PV was performed. After the contrast ...

    Abstract A 68-year-old man was referred for pulmonary vein (PV) isolation. Access to the left atrium was obtained via a single transseptal puncture. A heparin bolus was given immediately after puncture. Angiography of the left PV was performed. After the contrast wash-out, a contrasted longitudinal thrombus was shown revolving within the left atrium for several seconds before being expelled through the mitral and aortic valves. It is common practice in these procedures to administer an intravenous bolus of heparin immediately after the transseptal puncture. However, heparin has latency to become effective, and this can result in thromboembolic events.
    MeSH term(s) Aged ; Anticoagulants/administration & dosage ; Atrial Fibrillation/surgery ; Heart Septum/surgery ; Heparin/administration & dosage ; Humans ; Male ; Pulmonary Veins/surgery ; Punctures/adverse effects ; Thrombosis/etiology ; Thrombosis/prevention & control ; Treatment Failure
    Chemical Substances Anticoagulants ; Heparin (9005-49-6)
    Language English
    Publishing date 2015-03
    Publishing country Germany
    Document type Case Reports ; Journal Article
    ZDB-ID 1082953-2
    ISSN 1435-1544 ; 0938-7412
    ISSN (online) 1435-1544
    ISSN 0938-7412
    DOI 10.1007/s00399-015-0357-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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