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  1. Article: Bladder diverticulectomy using a pre-peritoneal,

    Tonzi, Michael / Watson, Mathew J / Singh, Amar

    Urology case reports

    2021  Volume 39, Page(s) 101753

    Abstract: A 64-year-old male with a history of urothelial carcinoma was found to have recurrence of his disease inside of a narrow neck bladder diverticulum on surveillance cystoscopy. The da Vinci Single Port robotic system was used to perform an extraperitoneal, ...

    Abstract A 64-year-old male with a history of urothelial carcinoma was found to have recurrence of his disease inside of a narrow neck bladder diverticulum on surveillance cystoscopy. The da Vinci Single Port robotic system was used to perform an extraperitoneal,
    Language English
    Publishing date 2021-06-11
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2745459-9
    ISSN 2214-4420
    ISSN 2214-4420
    DOI 10.1016/j.eucr.2021.101753
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Extended Lymph Node Sampling During Surgery for Pediatric Renal Tumors Concerning for Malignancy Does Not Increase Postoperative Complication Rates.

    Walker, Jonathan P / Han, Daniel S / Nicklawsky, Andrew / Boxley, Peter / Morrison, Jeffery / Tonzi, Michael / Bruny, Jennifer / Roach, Jonathan P / Cost, Nicholas G

    The Journal of urology

    2023  Volume 209, Issue 6, Page(s) 1186–1193

    Abstract: Purpose: Although Children's Oncology Group renal tumor protocols mandate lymph node sampling during extirpative surgery for pediatric renal tumors, lymph node sampling is often omitted or low yield. Concerns over morbidity associated with extended ... ...

    Abstract Purpose: Although Children's Oncology Group renal tumor protocols mandate lymph node sampling during extirpative surgery for pediatric renal tumors, lymph node sampling is often omitted or low yield. Concerns over morbidity associated with extended lymph node sampling have led to hesitancy in adopting a formal lymph node sampling template. We hypothesized that complications in children undergoing lymph node sampling for renal tumors would be rare, and not associated with the number of lymph nodes sampled.
    Materials and methods: A single-institution, retrospective review of patients aged 0-18 years undergoing extirpative renal surgery with lymph node sampling for a suspected malignancy between 2005 and 2019 was performed. Patients with 0 or an unknown number of lymph nodes sampled or <150 days of follow-up were excluded. A "clinically significant" complication was defined as any Clavien complication ≥III, small-bowel obstruction, chylous ascites, organ injury, or wound infection. The number of lymph nodes sampled and its influence on the odds of experiencing a clinically significant complication was examined.
    Results: A total of 144 patients met inclusion criteria. Median patient age was 38 months. Twenty-one patients (15%) had a clinically significant complication, the most common of which was ileus/small-bowel obstruction (n=16). In a multivariable analysis, increased lymph node yield was not found to influence the odds of experiencing a clinically significant complication (
    Conclusions: In this cohort, there was no statistically significant difference in clinically significant complications in patients who underwent more extensive lymph node sampling during surgery for a suspected malignant pediatric renal tumor. Future studies on protocol adherence, staging accuracy, and survival trends using a lymph node sampling template in these patients should be performed.
    MeSH term(s) Humans ; Child ; Kidney Neoplasms/pathology ; Lymph Nodes/surgery ; Lymph Nodes/pathology ; Lymph Node Excision/adverse effects ; Lymph Node Excision/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/pathology ; Retrospective Studies ; Neoplasm Staging
    Language English
    Publishing date 2023-02-23
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003390
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Reply by Authors.

    Han, Daniel S / Walker, Jonathan P / Nicklawsky, Andrew / Boxley, Peter / Halstead, N Valeska / Tonzi, Michael / Hecht, Sarah L / Staley, Alyse / Eguchi, Megan / Cockburn, Myles G / Roach, Jonathan P / Saltzman, Amanda F / Cost, Nicholas G

    The Journal of urology

    2023  Volume 209, Issue 3, Page(s) 590

    Language English
    Publishing date 2023-03-01
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003092.02
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Pediatric Small Renal Masses: Can Tumor Size Predict Histology and the Potential for Nephron-sparing Surgery?

    Han, Daniel S / Walker, Jonathan P / Nicklawsky, Andrew / Boxley, Peter / Halstead, N Valeska / Tonzi, Michael / Hecht, Sarah L / Staley, Alyse / Eguchi, Megan / Cockburn, Myles G / Roach, Jonathan P / Saltzman, Amanda F / Cost, Nicholas G

    The Journal of urology

    2022  Volume 209, Issue 3, Page(s) 582–590

    Abstract: Purpose: The majority of children with unilateral renal masses suspicious for malignancy undergo radical nephrectomy, while nephron-sparing surgery is reserved for select cases. We investigated the impact of tumor size on the probability of histology. ... ...

    Abstract Purpose: The majority of children with unilateral renal masses suspicious for malignancy undergo radical nephrectomy, while nephron-sparing surgery is reserved for select cases. We investigated the impact of tumor size on the probability of histology. We hypothesized that pediatric small renal masses are more likely benign or non-Wilms tumor, thus potentially appropriate for nephron-sparing surgery.
    Materials and methods: The SEER (Surveillance, Epidemiology, and End Results) database was analyzed for patients aged 0-18 years diagnosed with a unilateral renal mass from 2000-2016. Statistical analysis was performed to help determine a tumor size cut point to predict Wilms tumor and assess the predictive value of tumor size on Wilms tumor histology. Additionally, a retrospective review was performed of patients 0-18 years old who underwent surgery for a unilateral renal mass at a single institution from 2005-2019. Statistical analysis was performed to assess the predictive value of tumor size on final histology.
    Results: From the SEER analysis, 2,016 patients were included. A total of 1,672 tumors (82.9%) were Wilms tumor. Analysis revealed 4 cm to be a suitable cut point to distinguish non-Wilms tumor. Tumors ≥4 cm were more likely Wilms tumor (OR 2.67,
    Conclusions: The probability that a pediatric unilateral renal mass is Wilms tumor increases with tumor size. Four centimeters is a logical cut point to start the conversation around defining pediatric small renal masses and may help predict nephron-sparing surgery-appropriate histology.
    MeSH term(s) Child ; Humans ; Infant, Newborn ; Infant ; Child, Preschool ; Adolescent ; Kidney Neoplasms/surgery ; Kidney Neoplasms/pathology ; Nephrons/surgery ; Nephrons/pathology ; Wilms Tumor/surgery ; Nephrectomy/methods ; Retrospective Studies
    Language English
    Publishing date 2022-11-29
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural
    ZDB-ID 3176-8
    ISSN 1527-3792 ; 0022-5347
    ISSN (online) 1527-3792
    ISSN 0022-5347
    DOI 10.1097/JU.0000000000003092
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Decreasing the prospect of upper extremity neuropraxia during robotic assisted laparoscopic prostatectomy: a novel technique.

    Watson, Matthew J / Koch, Brandon / Tonzi, Michael / Xu, Raymond / Heath, Gregory / Lute, Brandon / Singh, Amar

    Journal of robotic surgery

    2020  Volume 14, Issue 5, Page(s) 733–738

    Abstract: Risk of intraoperative neuropathic injury in minimally invasive surgery has been established as a leading complication. Continuous intraoperative neuromonitoring (IONM), such as upper extremity somatosensory evoked potentials (ueSSEPs), to decrease ... ...

    Abstract Risk of intraoperative neuropathic injury in minimally invasive surgery has been established as a leading complication. Continuous intraoperative neuromonitoring (IONM), such as upper extremity somatosensory evoked potentials (ueSSEPs), to decrease peripheral nerve injury due to positional stress has been described. Robotic-assisted laparoscopic prostatectomy (RALP) requires steep Trendelenberg, which may predispose patients to upper extremity neuropraxia. Subdermal stimulating electrodes were placed on the patients' bilateral wrists over the ulnar nerve and the nerve was stimulated. Realtime waveforms were compared to baseline data to prevent and detect injury to the ulnar nerve. Established intervention criteria, indicating risk for neuropathic damage necessitating intraoperative patient repositioning, was a 50% loss in amplitude or a 10% increase in latency. One hundred and forty three patients received RALP with IONM. 17 of 143 patients (11.8%) met ueSSEP intervention criteria. Only weight was significantly different between the two groups (p = 0.04). Mean reduction in amplitude was 79.9% (SE 4.1). Average amplitude loss duration was 22 min (SE 4.0). Weight and BMI were correlated to the degree of amplitude reduction (p = 0.03 and < 0.01), while operative time and DM approached significance (p = 0.09 and p = 0.14). This is the first study to use IONM to reduce the risk of nerve injury during genitourinary surgery. Realtime nerve monitoring using ueSSEP allowed for upper extremity intraoperative monitoring and repositioning. This may decrease the risk of upper extremity neuropraxia due to malpositioning during RALP. Weight and BMI were identified as risk factors for possible nerve injury. Further data collection and analysis to preoperatively stratify patients for application of IONM during RALP is currently ongoing.
    MeSH term(s) Aged ; Body Mass Index ; Evoked Potentials, Somatosensory ; Humans ; Laparoscopy/adverse effects ; Laparoscopy/methods ; Male ; Middle Aged ; Monitoring, Intraoperative/methods ; Patient Positioning/adverse effects ; Peripheral Nerve Injuries/etiology ; Peripheral Nerve Injuries/prevention & control ; Prostatectomy/adverse effects ; Prostatectomy/methods ; Risk Factors ; Robotic Surgical Procedures/adverse effects ; Robotic Surgical Procedures/methods ; Upper Extremity/innervation
    Language English
    Publishing date 2020-01-29
    Publishing country England
    Document type Journal Article
    ZDB-ID 2268283-1
    ISSN 1863-2491 ; 1863-2483
    ISSN (online) 1863-2491
    ISSN 1863-2483
    DOI 10.1007/s11701-020-01047-w
    Database MEDical Literature Analysis and Retrieval System OnLINE

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