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  1. Article: Evaluation of 3 Hemoglobin A1c Point of Care Instruments. Point of Care Testing for HbA1c: Evaluation of Cobas b101, B-Analyst and Afinion™.

    Toro-Crespo, María De / Sánchez-Mora, Catalina / Fernández-Riejos, Patricia / Maesa-Márquez, José M / González-Rodríguez, Concepción

    Clinical laboratory

    2017  Volume 63, Issue 7, Page(s) 1107–1112

    MeSH term(s) Blood Cell Count ; Diabetes Mellitus/diagnosis ; Glycated Hemoglobin A ; Humans ; Point-of-Care Systems ; Point-of-Care Testing
    Chemical Substances Glycated Hemoglobin A
    Language English
    Publishing date 2017-07-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1307629-2
    ISSN 1433-6510 ; 0941-2131
    ISSN 1433-6510 ; 0941-2131
    DOI 10.7754/Clin.Lab.2017.161212
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.170: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 25: Show issues

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  2. Article: Comparison of Citrate Buffer with Sodium Fluoride as Additives in Determining Glycemia.

    Toro-Crespo, Maria de / Maesa-Marquez, Jose M / Sanchez-Margalet, Victor / Gonzalez-Rodriguez, Concepcion / Fernandez-Riejos, Patricia

    Clinical laboratory

    2017  Volume 63, Issue 11, Page(s) 1939–1944

    Abstract: Background: The objectives of this study are to compare the effect of sodium fluoride and citrate on the stability of glucose in samples maintained at room temperature up to three hours, and to assess the clinical impact in the O'Sullivan test results ... ...

    Abstract Background: The objectives of this study are to compare the effect of sodium fluoride and citrate on the stability of glucose in samples maintained at room temperature up to three hours, and to assess the clinical impact in the O'Sullivan test results after changing the additives in the collecting tubes.
    Methods: The selected population was pregnant women between the 24th and 28th week of gestation, who were at the health center to undergo the O'Sullivan test as part of the screening program for GDM (gestacional diabetes mellitus). Two blood samples were extracted from each patient: one using a tube with citrate and sodium fluoride buffer (tubes Vacuette Glucomedics citrate, 2 mL, Ref 454347) (tube C) and another containing just sodium fluoride (BD Vacationer tubes FX fluoride, 2 mL, Ref 368920) (tube F). The statistical treatment of the data was performed using SPSS version 24 and Method validator. Finally, we assessed the real clinical impact of replacing tubes C for tubes F in the classification of pregnant women. To do so, we collected the results of O'Sullivan tests conducted in our hospital during a year, all of them done in tubes F, and we applied the mean difference calculated in T = 1 to estimate the number of pregnant women that should be reclassified.
    Results: The average glycaemia in tubes C are significantly greater than average glycaemia in tubes F (p < 0.05) at all time points. The clinical impact assessment was done over the 6,526 O'Sullivan test results with a prevalence of positive tests of 21.35%. The prevalence using tubes C instead of tubes F estimated with mean differences previously calculated is 33.45%.
    Conclusions: The glucose concentrations in tubes F stored at room temperature up to 3 hours were significantly lower (p < 0.05) than those measured in tubes C stored under the same conditions. We observed that it is in the first minutes after extraction, while the samples are collected and aliquots done, that the glucose consumption occurs in tubes F, but not in tubes C. There is a need to change the preanalytical conditions to prevent any loss of glucose. This will enable more accurate diagnosis and management of diabetes mellitus.
    MeSH term(s) Blood Glucose/analysis ; Citric Acid ; Diabetes, Gestational/blood ; Diabetes, Gestational/diagnosis ; Female ; Humans ; Pregnancy ; Sodium Fluoride
    Chemical Substances Blood Glucose ; Citric Acid (2968PHW8QP) ; Sodium Fluoride (8ZYQ1474W7)
    Language English
    Publishing date 2017-01-11
    Publishing country Germany
    Document type Comparative Study ; Evaluation Studies ; Journal Article
    ZDB-ID 1307629-2
    ISSN 1433-6510 ; 0941-2131
    ISSN 1433-6510 ; 0941-2131
    DOI 10.7754/Clin.Lab.2017.170621
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ud II Zs.170: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 25: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

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