LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 4 of total 4

Search options

  1. Article ; Online: Brief Report: Impact of COVID-19 on Individuals with ASD and Their Caregivers: A Perspective from the SPARK Cohort.

    White, L Casey / Law, J Kiely / Daniels, Amy M / Toroney, Jaimie / Vernoia, Brianna / Xiao, Sabrina / Feliciano, Pamela / Chung, Wendy K

    Journal of autism and developmental disorders

    2021  Volume 51, Issue 10, Page(s) 3766–3773

    Abstract: The impact of the 2019 coronavirus pandemic (COVID-19) in the United States is unprecedented, with unknown implications for the autism community. We surveyed 3502 parents/caregivers of individuals with an autism spectrum disorder (ASD) enrolled in Simons ...

    Abstract The impact of the 2019 coronavirus pandemic (COVID-19) in the United States is unprecedented, with unknown implications for the autism community. We surveyed 3502 parents/caregivers of individuals with an autism spectrum disorder (ASD) enrolled in Simons Powering Autism Research for Knowledge (SPARK) and found that most individuals with ASD experienced significant, ongoing disruptions to therapies. While some services were adapted to telehealth format, most participants were not receiving such services at follow-up, and those who were reported minimal benefit. Children under age five had the most severely disrupted services and lowest reported benefit of telehealth adaptation. Caregivers also reported worsening ASD symptoms and moderate family distress. Strategies to support the ASD community should be immediately developed and implemented.
    MeSH term(s) Autism Spectrum Disorder/therapy ; Autistic Disorder ; COVID-19 ; Caregivers ; Child ; Humans ; SARS-CoV-2 ; United States
    Language English
    Publishing date 2021-01-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 391999-7
    ISSN 1573-3432 ; 0162-3257
    ISSN (online) 1573-3432
    ISSN 0162-3257
    DOI 10.1007/s10803-020-04816-6
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 765: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: Reasons for not seeking general medical care among individuals with serious mental illness.

    Mojtabai, Ramin / Cullen, Bernadette / Everett, Anita / Nugent, Katie L / Sawa, Akira / Sharifi, Vandad / Takayanagi, Yoichiro / Toroney, Jaimie S / Eaton, William W

    Psychiatric services (Washington, D.C.)

    2014  Volume 65, Issue 6, Page(s) 818–821

    Abstract: Objective: The study compared delays in seeking general medical care among adults with serious mental illness and a general population sample. Associations of delays with health status and use of emergency department services among individuals with ... ...

    Abstract Objective: The study compared delays in seeking general medical care among adults with serious mental illness and a general population sample. Associations of delays with health status and use of emergency department services among individuals with serious mental illness were also assessed.
    Methods: Data for 271 persons with serious mental illness (clinic sample) and 40,016 participants in the National Health Interview Survey (NHIS sample) were compared.
    Results: Fifty-three percent of the clinic sample and 13% of the NHIS sample reported delays, most because of difficulties accessing services. In the clinic sample, delays were associated with receipt of routine care at a public clinic, rather than a physician's office; more severe depressive symptoms; and functional difficulties. Delays were also associated with poorer health status and use of emergency department services.
    Conclusions: Integration of services as envisioned in the Affordable Care Act and targeted case management may reduce delays among individuals with serious mental illness.
    MeSH term(s) Adult ; Attitude to Health ; Bipolar Disorder/psychology ; Depressive Disorder, Major/psychology ; Emergency Service, Hospital/utilization ; Female ; Health Services/utilization ; Health Services Accessibility ; Humans ; Male ; Middle Aged ; Patient Acceptance of Health Care/psychology ; Patient Protection and Affordable Care Act ; Psychotic Disorders/psychology ; Schizophrenia ; Schizophrenic Psychology
    Language English
    Publishing date 2014-06-01
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 1220173-x
    ISSN 1557-9700 ; 1075-2730
    ISSN (online) 1557-9700
    ISSN 1075-2730
    DOI 10.1176/appi.ps.201300348
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 416: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Article ; Online: Interrater reliability of the modified Monitoring of Side Effects Scale for assessment of adverse effects of psychiatric medication in clinical and research settings.

    Nugent, Katie L / Spahr, Erin / Toroney, Jaimie / Mojtabai, Ramin / Nettles, Carrie / Turner, Lydia W / Fenton, Ashley / Spivak, Amethyst / Cullen, Bernadette A / Everett, Anita / Eaton, William W

    Journal of clinical psychopharmacology

    2015  Volume 35, Issue 3, Page(s) 324–328

    Abstract: The assessment of adverse effects of psychiatric medications is important in clinical and research settings because they are often associated with medication discontinuation, symptom exacerbation, and reduced quality of life. Currently available ... ...

    Abstract The assessment of adverse effects of psychiatric medications is important in clinical and research settings because they are often associated with medication discontinuation, symptom exacerbation, and reduced quality of life. Currently available assessment tools are either limited with regard to the number and variety of included adverse effects or are not practical for use in most clinical or research settings owing to specialized rater training required and administration length. This report describes a modification of the Monitoring of Side Effects Scale (MOSES), an established adverse effect rating scale, by adding severity anchors to improve its reliability and ease of use. Interrater reliability was good for 7 of the 8 bodily adverse effects assessed, with intraclass correlation coefficients ranging from 0.76 to 0.91 in a sample of patients with severe mental illness. This modified version of the Monitoring of Side Effects Scale holds promise as a useful tool for assessing medication adverse effects in clinical and research settings.
    MeSH term(s) Adult ; Drug-Related Side Effects and Adverse Reactions/diagnosis ; Female ; Humans ; Male ; Mental Disorders/drug therapy ; Observer Variation ; Psychotropic Drugs/adverse effects ; Psychotropic Drugs/therapeutic use ; Reproducibility of Results ; Severity of Illness Index
    Chemical Substances Psychotropic Drugs
    Language English
    Publishing date 2015-06
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 604631-9
    ISSN 1533-712X ; 0271-0749
    ISSN (online) 1533-712X
    ISSN 0271-0749
    DOI 10.1097/JCP.0000000000000311
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.A 1664: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  4. Article: Subregional neuroanatomical change as a biomarker for Alzheimer's disease

    Holland, Dominic / Brewer, James B / Hagler, Donald J / Fenema-Notestine, Christine / Dale, Anders M / Weiner, Michael / Thal, Leon / Petersen, Ronald / Jack, Clifford R. Jr / Jagust, William / Trojanowki, John / Toga, Arthur W / Beckett, Laurel / Green, Robert C / Gamst, Anthony / Potter, William Z / Montine, Tom / Anders, Dale / Bernstein, Matthew /
    Felmlee, Joel / Fox, Nick / Thompson, Paul / Schuff, Norbert / Alexander, Gene / Bandy, Dan / Koeppe, Robert A / Foster, Norm / Reiman, Eric M / Chen, Kewei / Shaw, Les / Lee, Virginia M.-Y / Korecka, Magdalena / Crawford, Karen / Neu, Scott / Harvey, Danielle / Kornak, John / Kachaturian, Zaven / Frank, Richard / Snyder, Peter J / Molchan, Susan / Kaye, Jeffrey / Vorobik, Remi / Quinn, Joseph / Schneider, Lon / Pawluczyk, Sonia / Spann, Bryan / Fleisher, Adam S / Vanderswag, Helen / Heidebrink, Judith L / Lord, Joanne L / Johnson, Kris / Doody, Rachelle S / Villanueva-Meyer, Javier / Chowdhury, Munir / Stern, Yaakov / Honig, Lawrence S / Bell, Karen L / Morris, John C / Mintun, Mark A / Schneider, Stacy / Marson, Daniel / Griffith, Randall / Badger, Beverly / Grossman, Hillel / Tang, Cheuk / Stern, Jessica / deToledo-Morrell, Leyla / Shah, Raj C / Bach, Julie / Duara, Ranjan / Isaacson, Richard / Strauman, Silvia / Albert, Marilyn S / Pedroso, Julia / Toroney, Jaimie / Rusinek, Henry / de Leon, Mony J / De Santi, Susan M / Doraiswamy, P. Murali / Petrella, Jeffrey R / Aiello, Marilyn / Clark, Christopher M / Pham, Cassie / Nunez, Jessica / Smith, Charles D / Given, Curtis A. II / Hardy, Peter / DeKosky, Steven T / Oakley, MaryAnn / Simpson, Donna M / Ismail, M. Saleem / Porsteinsson, Anton / McCallum, Colleen / Cramer, Steven C / Mulnard, Ruth A / McAdams-Ortiz, Catherine / Diaz-Arrastia, Ramon / Martin-Cook, Kristen / DeVous, Michael / Levey, Allan I / Lah, James J / Cellar, Janet S / Burns, Jeffrey M / Anderson, Heather S / Laubinger, Mary M / Bartzokis, George / Silverman, Daniel H.S / Lu, Po H / Fletcher, Rita / Parfitt, Francine / Johnson, Heather / Farlow, Martin / Herring, Scott / Hake, Ann M / van Dyck, Christopher H / MacAvoy, Martha G / Bifano, Laurel A / Chertkow, Howard / Bergman, Howard / Hosein, Chris / Black, Sandra / Graham, Simon / Caldwell, Curtis / Feldman, Howard / Assaly, Michele / Hsiung, Ging-Yuek R / Kertesz, Andrew / Rogers, John / Trost, Dick / Bernick, Charles / Gitelman, Darren / Johnson, Nancy / Mesulam, Marsel / Sadowsky, Carl / Villena, Teresa / Mesner, Scott / Aisen, Paul S / Johnson, Kathleen B / Behan, Kelly E / Sperling, Reisa A / Rentz, Dorene M / Johnson, Keith A / Rosen, Allyson / Tinklenberg, Jared / Ashford, Wes / Sabbagh, Marwan / Connor, Donald / Obradov, Sanja / Killiany, Ron / Norbash, Alex / Obisesan, Thomas O / Jayam-Trouth, Annapurni / Wang, Paul / Auchus, Alexander P / Huang, Juebin / Friedland, Robert P / DeCarli, Charles / Fletcher, Evan / Carmichael, Owen / Kittur, Smita / Mirje, Seema / Johnson, Sterling C / Borrie, Michael / Lee, T.-Y / Asthana, Sanjay / Carlsson, Cynthia M / Potkin, Steven G / Highum, Diane / Preda, Adrian / Nguyen, Dana / Tariot, Pierre N / Hendin, Barry A / Scharre, Douglas W / Kataki, Maria / Beversdorf, David Q / Zimmerman, Earl A / Celmins, Dzintra / Brown, Alice D / Gandy, Sam / Marenberg, Marjorie E / Rovner, Barry W / Pearlson, Godfrey / Blank, Karen / Anderson, Karen / Saykin, Andrew J / Santulli, Robert B / Pare, Nadia / Williamson, Jeff D / Sink, Kaycee M / Potter, Huntington / Ashok Raj, B / Giordano, Amy / Ott, Brian R / Wu, Chuang-Kuo / Cohen, Ronald / Wilks, Kerri L / Safirstein, Beth E

    Proceedings of the National Academy of Sciences of the United States of America. 2009 Dec. 8, v. 106, no. 49

    2009  

    Abstract: Regions of the temporal and parietal lobes are particularly damaged in Alzheimer's disease (AD), and this leads to a predictable pattern of brain atrophy. In vivo quantification of subregional atrophy, such as changes in cortical thickness or structure ... ...

    Abstract Regions of the temporal and parietal lobes are particularly damaged in Alzheimer's disease (AD), and this leads to a predictable pattern of brain atrophy. In vivo quantification of subregional atrophy, such as changes in cortical thickness or structure volume, could lead to improved diagnosis and better assessment of the neuroprotective effects of a therapy. Toward this end, we have developed a fast and robust method for accurately quantifying cerebral structural changes in several cortical and subcortical regions using serial MRI scans. In 169 healthy controls, 299 subjects with mild cognitive impairment (MCI), and 129 subjects with AD, we measured rates of subregional cerebral volume change for each cohort and performed power calculations to identify regions that would provide the most sensitive outcome measures in clinical trials of disease-modifying agents. Consistent with regional specificity of AD, temporal-lobe cortical regions showed the greatest disease-related changes and significantly outperformed any of the clinical or cognitive measures examined for both AD and MCI. Global measures of change in brain structure, including whole-brain and ventricular volumes, were also elevated in AD and MCI, but were less salient when compared to changes in normal subjects. Therefore, these biomarkers are less powerful for quantifying disease-modifying effects of compounds that target AD pathology. The findings indicate that regional temporal lobe cortical changes would have great utility as outcome measures in clinical trials and may also have utility in clinical practice for aiding early diagnosis of neurodegenerative disease.
    Keywords Alzheimer disease ; atrophy ; biomarkers ; brain ; clinical trials ; cognition ; early diagnosis ; magnetic resonance imaging ; neurodegenerative diseases ; neuroprotective effect ; therapeutics
    Language English
    Dates of publication 2009-1208
    Size p. 20954-20959.
    Publishing place National Academy of Sciences
    Document type Article
    ZDB-ID 209104-5
    ISSN 1091-6490 ; 0027-8424
    ISSN (online) 1091-6490
    ISSN 0027-8424
    DOI 10.1073/pnas.0906053106
    Database NAL-Catalogue (AGRICOLA)

    More links

    Kategorien

    In stock of ZB MED Bonn / Germany

    Z 4' 63/44: Show issues
    87/25270: Show issues
    Qa 4' 169/3: Show issues
    Z 8.7: Show issues

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top