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  1. AU="Torre, Guadalupe Maza-De La"
  2. AU="Miyachi, Hiroyuki"
  3. AU=Magar Rishikesh

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  1. Article: Blood system ABO antigens as risk factor for severity of SARS-CoV-2 infection.

    Torres-Alarcón, Carmen G / García-Ruíz, Antonio / Cañete-Ibáñez, Cesar R / Morales-Pogoda, Irving I / Muñoz-Arce, Carlos M / Cid-Domínguez, Blanca E / Montalvo-Bárcenas, Maribel / Torre, Guadalupe Maza-de la / Sandoval-López, Chantal / Gaytán-Guzmán, Emanuel / Correo-Zamora, José D

    Gaceta medica de Mexico

    2021  Volume 157, Issue 2, Page(s) 174–180

    Abstract: Introduction: Whether there is an influence of the ABO blood system on SARS-CoV-2 infection is unknown.: Objective: To analyze if there is an association between the ABO system antigens and susceptibility to and severity of SARS-CoV-2 infection.: ... ...

    Title translation Antígenos del sistema sanguíneo ABO como factor de riesgo para la gravedad de la infección por SARS-CoV-2.
    Abstract Introduction: Whether there is an influence of the ABO blood system on SARS-CoV-2 infection is unknown.
    Objective: To analyze if there is an association between the ABO system antigens and susceptibility to and severity of SARS-CoV-2 infection.
    Material and methods: The frequency of ABO system antigens was compared in 73 confirmed cases of SARS-CoV-2 infection and 52 clinically healthy donors. Infection severity was assessed by comparing the frequency of antigens by disease severity and mortality.
    Results: The risk of suffering from SARS-CoV-2 infection increases in subjects with A vs. non-A antigen (OR = 1.45; 95 % CI: 1.061-1.921). Blood phenotype O reduces the risk of SARS-CoV-2 infection (OR = 0.686; 95 % CI: 0.522-0.903). No differences were found regarding disease severity. In critically ill patients, the risk of mortality increased in subjects with A vs. non-A antigen (OR = 3.34; 95 % CI: 1.417-8.159).
    Conclusion: Blood group A is a risk factor for SARS-CoV-2 infection, but not for disease severity, although in critically ill patients it is a risk factor for mortality.
    MeSH term(s) ABO Blood-Group System/adverse effects ; ABO Blood-Group System/immunology ; Adult ; Aged ; COVID-19/blood ; COVID-19/epidemiology ; COVID-19/immunology ; COVID-19/mortality ; Case-Control Studies ; Confidence Intervals ; Critical Illness ; Disease Susceptibility/blood ; Disease Susceptibility/immunology ; Female ; Humans ; Male ; Middle Aged ; Odds Ratio ; Risk Factors ; Severity of Illness Index ; Young Adult
    Chemical Substances ABO Blood-Group System
    Language English
    Publishing date 2021-07-16
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.20000498
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Epidemiology of hospitalized patients with COVID-19 in a tertiary care hospital.

    Torre, Guadalupe Maza-De La / Montelongo-Mercado, Edgardo A / Noyola-Villalobos, Héctor F / García-Ruiz, Antonio / Hernández-Díaz, Sergio / Santiago-Torres, Martha / Moreno-Delgado, Luis F / Carrera-Altamirano, Ricardo / Muñoz-Monroy, Omar E / Martínez-Cuazitl, Adriana / Martínez-González, Mayra A / Vázquez-Medina, Martín U / Alvarado-Uribe, Óscar / Torres-Vázquez, Julián / Figueroa-Peña, Aldo / Martínez-Salazar, Iván N

    Gaceta medica de Mexico

    2021  Volume 157, Issue 3, Page(s) 237–244

    Abstract: Introduction: COVID-19, caused by the betacoronavirus SARS-CoV-2, has overwhelmed the world's health systems.: Objective: To describe the epidemiological characteristics of patients treated in a tertiary care hospital.: Methods: A retrospective ... ...

    Title translation Epidemiología de los pacientes hospitalizados con COVID-19 en un hospital de tercer nivel.
    Abstract Introduction: COVID-19, caused by the betacoronavirus SARS-CoV-2, has overwhelmed the world's health systems.
    Objective: To describe the epidemiological characteristics of patients treated in a tertiary care hospital.
    Methods: A retrospective cohort study of patients diagnosed with or suspected of having COVID-19 from March 23 to July 31, 2020 was conducted.
    Results: 4,401 patients were hospitalized at Central Military Hospital, out of which 35 % were beneficiaries, 26 % civilians, 28 % active military personnel, and only 11 %, retired military personnel. Male gender predominated, both in hospitalized patients and in those who died, as well as the O+ group and absence of comorbidities; among the observed comorbidities, the main ones were overweight and diabetes. Hospitalized patients' median age was 49 years, while median age of those who died was 62 years; women older than 51 years had a higher risk of dying. Adjusted case fatality rate was 18.5 %; 50 % died within the first six days.
    Conclusions: In this study, the epidemiological characteristics and main comorbidities in Mexican patients with SARS-CoV-2 infection were identified.
    MeSH term(s) Adult ; Age Factors ; Aged ; Aged, 80 and over ; COVID-19/epidemiology ; COVID-19/mortality ; Cohort Studies ; Diabetes Mellitus/epidemiology ; Female ; Hospitalization/statistics & numerical data ; Humans ; Male ; Mexico/epidemiology ; Middle Aged ; Overweight/epidemiology ; Retrospective Studies ; Risk Factors ; Sex Factors ; Tertiary Care Centers ; Young Adult
    Language English
    Publishing date 2021-10-19
    Publishing country Mexico
    Document type Journal Article
    ZDB-ID 425456-9
    ISSN 0016-3813
    ISSN 0016-3813
    DOI 10.24875/GMM.M21000552
    Database MEDical Literature Analysis and Retrieval System OnLINE

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