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Article ; Online: Sleep patterns are associated with cardiometabolic risk factors in nine-year-old Swedish children.

Nilsson, Ellinor / Delisle Nyström, Christine / Migueles, Jairo H / Baurén, Hanna / Marin-Jimenez, Nuria / Henström, Maria / Torres López, Lucía V / Löf, Marie

Acta paediatrica (Oslo, Norway : 1992)

2024

Abstract: Aim: Sleep duration and bedtime may play a role in children's cardiometabolic health, but research is lacking. This study examined associations between sleep patterns and cardiometabolic risk factors in Swedish nine-year-olds.: Methods: This cross- ... ...

Abstract	Aim: Sleep duration and bedtime may play a role in children's cardiometabolic health, but research is lacking. This study examined associations between sleep patterns and cardiometabolic risk factors in Swedish nine-year-olds. Methods: This cross-sectional study used data from three studies, where identical outcome measures were conducted in 411 nine-year-olds, 51% boys, between 2016 and 2020. Sleep was assessed with wrist-worn accelerometers and sleep journals. Children were grouped based on meeting the sleep guidelines of 9-11 h and going to bed early or late based on the median bedtime. Analysis of covariance was used to examine associations between sleep patterns and cardiometabolic risk factors. Results: Meeting sleep guidelines and going to bed early were associated with lower metabolic syndrome score (-0.15 vs. 0.42, p = 0.029), insulin resistance (0.30 vs. 0.60, p = 0.025) and insulin levels (6.80 vs. 8.87 mIU/L, p = 0.034), compared with their peers who did not meet the guidelines and went to bed later. When adjusting for total sleep time, analyses still showed associations with the metabolic syndrome score (-0.19 vs. 0.50, p = 0.011). Conclusion: The findings indicate that good sleep patterns could help mediate positive overall cardiometabolic health in children.
Language	English
Publishing date	2024-04-27
Publishing country	Norway
Document type	Journal Article
ZDB-ID	203487-6
ISSN	1651-2227 ; 0365-1436 ; 0803-5253
ISSN (online)	1651-2227
ISSN	0365-1436 ; 0803-5253
DOI	10.1111/apa.17254
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Article ; Online: Sleep Behaviors and the Shape of Subcortical Brain Structures in Children with Overweight/Obesity: A Cross-Sectional Study.

Cadenas-Sanchez, Cristina / Migueles, Jairo H / Torres-Lopez, Lucia V / Verdejo-Román, Juan / Jiménez-Pavón, David / Hillman, Charles H / Catena, Andrés / Ortega, Francisco B

Indian journal of pediatrics

2024

Abstract: Objectives: To examine the relationship between sleep and subcortical brain structures using a shape analysis approach.: Methods: A total of 98 children with overweight/obesity (10.0 ± 1.1 y, 59 boys) were included in the cross-sectional analyses. ... ...

Abstract	Objectives: To examine the relationship between sleep and subcortical brain structures using a shape analysis approach. Methods: A total of 98 children with overweight/obesity (10.0 ± 1.1 y, 59 boys) were included in the cross-sectional analyses. Sleep behaviors (i.e., wake time, sleep onset time, total time in bed, total sleep time, sleep efficiency, and wakening after sleep onset) were estimated with wrist-worn accelerometers. The shape of the subcortical brain structures was acquired by magnetic resonance imaging. A partial correlation permutation approach was used to examine the relationship between sleep behaviors and brain shapes. Results: Among all the sleep variables studied, only total time in bed was significantly related to pallidum and putamen structure, such that those children who spent more time in bed had greater expansions in the right and left pallidum (211-751 voxels, all p's <0.04) and right putamen (1783 voxels, p = 0.03). Conclusions: These findings suggest that more time in bed was related to expansions on two subcortical brain regions in children with overweight/obesity.
Language	English
Publishing date	2024-04-04
Publishing country	India
Document type	Journal Article
ZDB-ID	218231-2
ISSN	0973-7693 ; 0019-5456
ISSN (online)	0973-7693
ISSN	0019-5456
DOI	10.1007/s12098-024-05094-1
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Article ; Online: Associations of Sleep-Related Outcomes with Behavioral and Emotional Functioning in Children with Overweight/Obesity.

Torres-Lopez, Lucia V / Cadenas-Sanchez, Cristina / Migueles, Jairo H / Henriksson, Pontus / Löf, Marie / Ortega, Francisco B

The Journal of pediatrics

2022 Volume 246, Page(s) 170–178.e2

Abstract: Objective: To evaluate the associations of parent-reported sleep-disordered breathing (SDB) and device-assessed sleep behaviors with behavioral and emotional functioning in pediatric patients with overweight/obesity.: Study design: A total of 109 ... ...

Abstract	Objective: To evaluate the associations of parent-reported sleep-disordered breathing (SDB) and device-assessed sleep behaviors with behavioral and emotional functioning in pediatric patients with overweight/obesity. Study design: A total of 109 children with overweight/obesity (mean age, 10.0 ± 1.1 years) were included in this cross-sectional study. We used the Spanish version of the Pediatric Sleep Questionnaire (PSQ) to assess SDB and its subscales (ie, snoring, daytime sleepiness, and inattention/hyperactivity). Device-assessed sleep behaviors (ie, wake time, sleep onset time, total time in bed, total sleep time, and waking after sleep onset) were estimated using wrist-worn accelerometers. We used the Behavior Assessment System for Children, second edition to assess behavioral and emotional functioning (ie, clinical scale: aggressiveness, hyperactivity, behavior problems, attention problems, atypicality, depression, anxiety, retreat, and somatization; adaptive scale: adaptability, social skills, and leadership). Results: SDB was positively associated with all clinical scale variables (all β > 0.197, P ≤ .041) and with lower adaptability and leadership (all β < -0.226, P < .021). Specifically, the PSQ subscale relating to daytime sleepiness was associated with higher attention problems, depression, anxiety, and retreat (all β > 0.196, P ≤ .045) and lower adaptability (β = -0.246, P = .011). The inattention/hyperactivity subscale was significantly associated with the entire clinical and adaptive scales (all β > \|0.192\|, P ≤ .046) except for somatization. The snoring subscale and device-assessed sleep behaviors were not related to any behavioral or emotional functioning variables. Conclusions: Our study suggests that SDB symptoms, but not device-assessed sleep behaviors, are associated with behavioral and emotional functioning in children with overweight/obesity. Specifically, daytime sleepiness, a potential SDB symptom, was related to higher attention problems, depression, anxiety, and retreat and lower adaptability.
MeSH term(s)	Child ; Cross-Sectional Studies ; Disorders of Excessive Somnolence/complications ; Humans ; Obesity/complications ; Overweight/complications ; Sleep ; Sleep Apnea Syndromes/complications ; Snoring/complications ; Surveys and Questionnaires
Language	English
Publishing date	2022-03-10
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	3102-1
ISSN	1097-6833 ; 0022-3476
ISSN (online)	1097-6833
ISSN	0022-3476
DOI	10.1016/j.jpeds.2022.03.006
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Article ; Online: Gene-exercise interaction on brain health in children with overweight/obesity: the ActiveBrains randomized controlled trial.

Plaza-Florido, Abel / Esteban-Cornejo, Irene / Mora-Gonzalez, Jose / Torres-Lopez, Lucia V / Osuna-Prieto, Francisco J / Gil-Cosano, Jose J / Radom-Aizik, Shlomit / Labayen, Idoia / Ruiz, Jonatan R / Altmäe, Signe / Ortega, Francisco B

Journal of applied physiology (Bethesda, Md. : 1985)

2023 Volume 135, Issue 4, Page(s) 775–785

Abstract: We investigated the interaction between a genetic score and an exercise intervention on brain health in children with overweight/obesity. One hundred one children with overweight/obesity (10.0 ± 1.5 yr, 59% girls) were randomized into a 20-wk combined ... ...

Abstract	We investigated the interaction between a genetic score and an exercise intervention on brain health in children with overweight/obesity. One hundred one children with overweight/obesity (10.0 ± 1.5 yr, 59% girls) were randomized into a 20-wk combined exercise intervention or a control group. Several cognitive and academic outcomes were measured with validated tests. Hippocampal volume was quantified using magnetic resonance imaging. Six brain health-related polymorphisms [rs6265 (
MeSH term(s)	Female ; Adult ; Humans ; Child ; Male ; Overweight/genetics ; Brain-Derived Neurotrophic Factor/genetics ; Obesity/genetics ; Brain ; Apolipoproteins E
Chemical Substances	Brain-Derived Neurotrophic Factor ; Apolipoproteins E
Language	English
Publishing date	2023-08-17
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
ZDB-ID	219139-8
ISSN	1522-1601 ; 0021-8987 ; 0161-7567 ; 8750-7587
ISSN (online)	1522-1601
ISSN	0021-8987 ; 0161-7567 ; 8750-7587
DOI	10.1152/japplphysiol.00435.2023
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Article ; Online: Effects of exercise on sleep in children with overweight/obesity: a randomized clinical trial.

Torres-Lopez, Lucia V / Migueles, Jairo H / Cadenas-Sanchez, Cristina / Bendtsen, Marcus / Henriksson, Pontus / Mora-Gonzalez, Jose / Löf, Marie / Chaput, Jean-Philippe / Ortega, Francisco B

Obesity (Silver Spring, Md.)

2023 Volume 32, Issue 2, Page(s) 281–290

Abstract: Objective: The objective of this study was to examine the chronic effects of a 20-week exercise training program on device-assessed sleep and sleep-disordered breathing; and to determine whether participating in a session of the exercise program had ... ...

Abstract	Objective: The objective of this study was to examine the chronic effects of a 20-week exercise training program on device-assessed sleep and sleep-disordered breathing; and to determine whether participating in a session of the exercise program had effects on device-assessed sleep the subsequent night in children with overweight/obesity. Methods: A randomized clinical trial was conducted from November 2014 to June 2016. A total of 109 children (age 8-11 years) with overweight/obesity were randomized into an exercise training or control group. The exercise program included aerobic and resistance training 3 to 5 days/week. The control group participants continued their usual lifestyle. Device-assessed sleep outcomes were measured using wrist-worn actigraphy at baseline, in the middle of the exercise program (10th week), and at postintervention for seven consecutive days (24 h/day), and sleep-disordered breathing was measured via the Pediatric Sleep Questionnaire. Results: The exercise training program had a statistically significant effect on wake after sleep onset time (-10.8 min/day, -0.5 SDs, p = 0.040). No other chronic or acute effects (i.e., the subsequent night of attending a session of the exercise training program) were observed on the remaining sleep outcomes. Conclusions: A 20-week exercise training program reduced wake after sleep onset time in children with overweight/obesity. Future randomized trials that include a sample of children with poor sleep health at baseline are needed to better appreciate the role of exercise in sleep health.
MeSH term(s)	Humans ; Child ; Overweight/complications ; Overweight/therapy ; Obesity/complications ; Obesity/therapy ; Exercise ; Sleep ; Sleep Apnea Syndromes/complications ; Sleep Apnea Syndromes/therapy
Language	English
Publishing date	2023-12-19
Publishing country	United States
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	2230457-5
ISSN	1930-739X ; 1071-7323 ; 1930-7381
ISSN (online)	1930-739X
ISSN	1071-7323 ; 1930-7381
DOI	10.1002/oby.23945
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Article ; Online: A 20-week exercise program improved total body and legs bone mineral density in children with overweight or obesity: The ActiveBrains randomized controlled trial.

Gil-Cosano, Jose J / Ubago-Guisado, Esther / Migueles, Jairo H / Cadenas-Sanchez, Cristina / Torres-Lopez, Lucia V / Martin-Matillas, Miguel / Labayen, Idoia / Ortega, Francisco B / Gracia-Marco, Luis

Journal of science and medicine in sport

2023 Volume 27, Issue 1, Page(s) 3–9

Abstract: Objectives: The aim of this study was to investigate the effect of a 20-week exercise program on bone mineral parameters in children with overweight or obesity.: Design: Randomized controlled trial.: Methods: This study took part from November 21, ...

Abstract	Objectives: The aim of this study was to investigate the effect of a 20-week exercise program on bone mineral parameters in children with overweight or obesity. Design: Randomized controlled trial. Methods: This study took part from November 21, 2014, to June 30, 2016, in Granada, Spain. A secondary analysis of this parallel-group randomized controlled trial was performed with 77 children with overweight or obesity (9.9 ± 1.2, 65 % boys) who were randomly allocated to exercise or control group. All participants received lifestyle recommendations. The control group continued their usual routines, whereas the exercise group attended a minimum of 3 supervised 90-minute sessions/week of aerobic plus resistance training for 20 weeks. A whole-body scan by dual-energy X-ray absorptiometry was carried out to obtain body composition at total body less head, arms, lumbar spine, pelvis, and legs. Results: Participants in the exercise group acquired significantly higher total body aBMD (mean z-score [95 % confidence intervals, CI], 0.607 [0.522-0.692]) compared with the participants in the control group (mean z-score, 0.472 [0.388-0.556]); difference between groups, 0.135 standard deviations [95 % CI 0.015-0.255], and legs aBMD (mean z-score, 0.629 [0.550-0.708]); control group (mean z-score, 0.518 [0.440-0.596]); difference between groups, 0.111 [0.001-0.222]; all p < 0.05. There were no significant differences between exercise group and control group at the remaining evaluated regions (p > 0.05). Conclusions: A 20-week non-specifically bone-targeted exercise program induced a small, yet significant, improvement on total body and legs aBMD in children with overweight or obesity. Future studies should investigate the interaction of weight status in the bone response to exercise programs. Trial registration: Prospectively registered in ClinicalTrials.gov Identifier: NCT02295072.
MeSH term(s)	Male ; Child ; Humans ; Female ; Overweight/therapy ; Overweight/complications ; Bone Density ; Leg ; Obesity/complications ; Exercise Therapy
Language	English
Publishing date	2023-10-12
Publishing country	Australia
Document type	Randomized Controlled Trial ; Journal Article
ZDB-ID	1437829-2
ISSN	1878-1861 ; 1440-2440
ISSN (online)	1878-1861
ISSN	1440-2440
DOI	10.1016/j.jsams.2023.10.005
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Article ; Online: Healthier Minds in Fitter Bodies: A Systematic Review and Meta-Analysis of the Association between Physical Fitness and Mental Health in Youth.

Cadenas-Sanchez, Cristina / Mena-Molina, Alejandra / Torres-Lopez, Lucia V / Migueles, Jairo H / Rodriguez-Ayllon, María / Lubans, David R / Ortega, Francisco B

Sports medicine (Auckland, N.Z.)

2021 Volume 51, Issue 12, Page(s) 2571–2605

Abstract: Background: Physical fitness is an important marker of current and future health status, yet the association between physical fitness and indicators of mental health in youth has not been systematically reviewed and meta-analyzed.: Objective: The aim ...

Abstract	Background: Physical fitness is an important marker of current and future health status, yet the association between physical fitness and indicators of mental health in youth has not been systematically reviewed and meta-analyzed. Objective: The aim of this work was to systematically review and meta-analyze the association between physical fitness components (i.e. cardiorespiratory fitness, muscular fitness, speed-agility, flexibility and fitness composite) and mental health indicators (i.e. psychological well-being and psychological ill-being) in preschoolers, children and adolescents. Design: Systematic review and meta-analysis. Data sources: Systematic searches were conducted in PubMed, Web of Science and Scopus from database inception to May 2020. Eligibility criteria: Studies (cross-sectional, longitudinal and intervention designs) were included if they measured at least one physical fitness component and one mental health indicator in healthy youth (2-18 years). Results: A total of 58 unique studies (52 cross-sectional, 4 longitudinal and 4 intervention studies) met all eligibility criteria and were included. There was a significant positive overall association between physical fitness and mental health in children and adolescents (pooled r = 0.206, p < 0.001). We found suggestive evidence of moderation by age group, fitness components and socioeconomic status (all p < 0.08). No relevant studies focusing on preschoolers were identified. Evidence based on longitudinal and intervention studies was limited. Conclusion: We observed a small to medium sized positive association between physical fitness and overall mental health in youth. However, as the majority of studies were cross-sectional, additional longitudinal and intervention studies are needed to provide evidence of causation. Trial registration: PROSPERO registration number CRD42017080005.
MeSH term(s)	Adolescent ; Cardiorespiratory Fitness ; Child ; Exercise ; Health Status ; Humans ; Mental Health ; Physical Fitness
Language	English
Publishing date	2021-07-27
Publishing country	New Zealand
Document type	Meta-Analysis ; Systematic Review
ZDB-ID	605911-9
ISSN	1179-2035 ; 0112-1642
ISSN (online)	1179-2035
ISSN	0112-1642
DOI	10.1007/s40279-021-01520-y
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Article ; Online: Equivalency of four research-grade movement sensors to assess movement behaviors and its implications for population surveillance.

Migueles, Jairo H / Molina-Garcia, Pablo / Torres-Lopez, Lucia V / Cadenas-Sanchez, Cristina / Rowlands, Alex V / Ebner-Priemer, Ulrich W / Koch, Elena D / Reif, Andreas / Ortega, Francisco B

Scientific reports

2022 Volume 12, Issue 1, Page(s) 5525

Abstract: the benefits of physical activity (PA) and sleep for health, accurate and objective population-based surveillance is important. Monitor-based surveillance has potential, but the main challenge is the need for replicable outcomes from different monitors. ... ...

Abstract	the benefits of physical activity (PA) and sleep for health, accurate and objective population-based surveillance is important. Monitor-based surveillance has potential, but the main challenge is the need for replicable outcomes from different monitors. This study investigated the agreement of movement behavior outcomes assessed with four research-grade activity monitors (i.e., Movisens Move4, ActiGraph GT3X+, GENEActiv, and Axivity AX3) in adults. Twenty-three participants wore four monitors on the non-dominant wrist simultaneously for seven days. Open-source software (GGIR) was used to estimate the daily time in sedentary, light, moderate-to-vigorous PA (MVPA), and sleep (movement behaviors). The prevalence of participants meeting the PA and sleep recommendations were calculated from each monitor's data. Outcomes were deemed equivalent between monitors if the absolute standardized difference and its 95% confidence intervals (CI
MeSH term(s)	Adult ; Exercise ; Humans ; Male ; Population Surveillance ; Reproducibility of Results ; Sedentary Behavior ; Wrist Joint
Language	English
Publishing date	2022-04-01
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	2615211-3
ISSN	2045-2322 ; 2045-2322
ISSN (online)	2045-2322
ISSN	2045-2322
DOI	10.1038/s41598-022-09469-2
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Article ; Online: Does sleep-disordered breathing add to impairments in academic performance and brain structure usually observed in children with overweight/obesity?

Torres-Lopez, Lucia V / Cadenas-Sanchez, Cristina / Migueles, Jairo H / Esteban-Cornejo, Irene / Molina-Garcia, Pablo / H Hillman, Charles / Catena, Andres / Ortega, Francisco B

European journal of pediatrics

2022 Volume 181, Issue 5, Page(s) 2055–2065

Abstract: Approximately 4-11% of children suffer from sleep-disordered breathing (SDB), and children with obesity are at increased risk. Both obesity and SDB have been separately associated with poorer brain health, yet whether SDB severity affects brain health in ...

Abstract	Approximately 4-11% of children suffer from sleep-disordered breathing (SDB), and children with obesity are at increased risk. Both obesity and SDB have been separately associated with poorer brain health, yet whether SDB severity affects brain health in children with obesity remains unanswered. This study aimed to examine associations of SDB severity with academic performance and brain structure (i.e., total brain and gray and white matter volumes and gray matter volume in the hippocampus) in children with overweight/obesity. One hundred nine children aged 8-12 years with overweight/obesity were included. SDB severity and its subscales (i.e., snoring, daytime sleepiness, and inattention/hyperactivity) were evaluated via the Pediatric Sleep Questionnaire (PSQ), and academic performance was evaluated with the Woodcock-Muñoz standardized test and school grades. Brain structure was assessed by magnetic resonance imaging. SDB severity was not associated with academic performance measured by the standardized test (all \|β\|> 0.160, P > 0.076), yet it was associated with the school grade point average (β = -0.226, P = 0.007) and natural and social science grades (β = -0.269, P = 0.024). Intention/hyperactivity seemed to drive these associations. No associations were found between SDB severity and the remaining school grades (all β < -0.188, P > 0.065) or brain volumes (all P > 0.05). Conclusion: Our study shows that SDB severity was associated with lower school grades, yet it was not associated with the standardized measurement of academic performance or with brain volumes in children with overweight/obesity. SDB severity may add to academic problems in children beyond the effects contributed by overweight/obesity status alone. What is known: • Sleep-disordered breathing (SDB) may affect brain structure and academic performance in children. • Children with overweight/obesity are at higher risk for the development of SDB, yet the comorbid obesity-SDB relationship with brain health has not been investigated thus far. What is new: • To our knowledge, this is the first study examining the associations of comorbid obesity-SDB severity with brain volumes and academic performance in children. • SDB symptoms may adversely affect academic performance at school in children with overweight/obesity, beyond the effects of weight status alone.
MeSH term(s)	Academic Performance ; Brain/diagnostic imaging ; Brain/pathology ; Child ; Humans ; Obesity/complications ; Overweight/complications ; Sleep Apnea Syndromes/complications ; Sleep Apnea Syndromes/pathology ; Surveys and Questionnaires
Language	English
Publishing date	2022-02-10
Publishing country	Germany
Document type	Journal Article
ZDB-ID	194196-3
ISSN	1432-1076 ; 0340-6199 ; 0943-9676
ISSN (online)	1432-1076
ISSN	0340-6199 ; 0943-9676
DOI	10.1007/s00431-022-04403-0
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Article ; Online: Role of physical fitness and functional movement in the body posture of children with overweight/obesity.

Molina-Garcia, Pablo / Plaza-Florido, Abel / Mora-Gonzalez, Jose / Torres-Lopez, Lucia V / Vanrenterghem, Jos / Ortega, Francisco B

Gait & posture

2020 Volume 80, Page(s) 331–338

Abstract: Background: Childhood obesity is known to negatively impact body posture with severe consequences for the musculoskeletal system. Physical performance could play a positive role in the body posture conformation of these children, but there is little ... ...

Abstract	Background: Childhood obesity is known to negatively impact body posture with severe consequences for the musculoskeletal system. Physical performance could play a positive role in the body posture conformation of these children, but there is little evidence to date. Research question: Is physical performance (i.e., physical fitness and functional movement) associated with a better body posture in children with overweight/obesity (OW/OB)? If so, is physical performance more determinant than their obesity degree in the body posture conformation? Method: A total of 62 children with OW/OB (10.86 ± 1.25 years, 58 % girls) were included. BMI, physical fitness components (one-repetition-maximum (1RM) arms and leg press, and ALPHA test battery), functional movement quality (Functional Movement Screen™) and body posture (two-dimensional photogrammetry) were evaluated. Results: Physical fitness components and functional movement were overall associated with a more aligned posture of the head, lumbar and thoracic spines and lower limb. BMI was associated with head protraction, thoracic hyperkyphosis, lumbar hyperlordosis and lower limb valgus. BMI was the best predictor of head and lumbar spine posture, cardiorespiratory fitness of lower limb posture in frontal plane, speed-agility of lower limb posture in the sagittal plane and functional movement of thoracic spine. Significance: Our findings reveal that physical fitness and functional movement are associated with a better global body posture in children with OW/OB, and that in some musculoskeletal structures are even better predictors than their obesity degree.
MeSH term(s)	Body Mass Index ; Cardiorespiratory Fitness ; Child ; Female ; Humans ; Kyphosis ; Lordosis ; Lower Extremity/physiopathology ; Male ; Movement ; Overweight/physiopathology ; Pediatric Obesity/physiopathology ; Physical Fitness ; Posture ; Spine/physiopathology
Language	English
Publishing date	2020-04-11
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	1162323-8
ISSN	1879-2219 ; 0966-6362
ISSN (online)	1879-2219
ISSN	0966-6362
DOI	10.1016/j.gaitpost.2020.04.001
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Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito