LIVIVO - Search results -

Search results

Result 1 - 10 of total 19

Search options

Article ; Online: Antimicrobial peptides for the treatment of pulmonary tuberculosis, allies or foes?

Rivas-Santiago, Bruno / Torres-Juarez, Flor

2018 Volume 24, Issue 10, Page(s) 1138–1147

Abstract: Tuberculosis is an ancient disease that has become a serious public health issue in recent years, although increasing incidence has been controlled, deaths caused by Mycobacterium tuberculosis have been accentuated due to the emerging of multi-drug ... ...

Abstract	Tuberculosis is an ancient disease that has become a serious public health issue in recent years, although increasing incidence has been controlled, deaths caused by Mycobacterium tuberculosis have been accentuated due to the emerging of multi-drug resistant strains and the comorbidity with diabetes mellitus and HIV. This situation is threatening the goals of World Health Organization (WHO) to eradicate tuberculosis in 2035. WHO has called for the creation of new drugs as an alternative for the treatment of pulmonary tuberculosis, among the plausible molecules that can be used are the Antimicrobial Peptides (AMPs). These peptides have demonstrated remarkable efficacy to kill mycobacteria in vitro and in vivo in experimental models, nevertheless, these peptides not only have antimicrobial activity but also have a wide variety of functions such as angiogenesis, wound healing, immunomodulation and other well-described roles into the human physiology. Therapeutic strategies for tuberculosis using AMPs must be well thought prior to their clinical use; evaluating comorbidities, family history and risk factors to other diseases, since the wide function of AMPs, they could lead to collateral undesirable effects.
MeSH term(s)	Animals ; Antimicrobial Cationic Peptides/chemistry ; Antimicrobial Cationic Peptides/pharmacology ; Antitubercular Agents/chemistry ; Antitubercular Agents/pharmacology ; Humans ; Microbial Sensitivity Tests ; Mycobacterium tuberculosis/drug effects ; Tuberculosis, Pulmonary/drug therapy
Chemical Substances	Antimicrobial Cationic Peptides ; Antitubercular Agents
Language	English
Publishing date	2018-03-28
Publishing country	United Arab Emirates
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Review
ZDB-ID	1304236-1
ISSN	1873-4286 ; 1381-6128
ISSN (online)	1873-4286
ISSN	1381-6128
DOI	10.2174/1381612824666180327162357
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4714: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Co-infection of mice with SARS-CoV-2 and

Baker, Paul J / Amaral, Eduardo P / Castro, Ehydel / Bohrer, Andrea C / Torres-Juárez, Flor / Jordan, Cassandra M / Nelson, Christine E / Barber, Daniel L / Johnson, Reed F / Hilligan, Kerry L / Mayer-Barber, Katrin D

Frontiers in immunology

2023 Volume 14, Page(s) 1240419

Abstract: Viral co-infections have been implicated in worsening tuberculosis (TB) and during the COVID-19 pandemic, the global rate of TB-related deaths has increased for the first time in over a decade. We and others have previously shown that a resolved prior or ...

Abstract	Viral co-infections have been implicated in worsening tuberculosis (TB) and during the COVID-19 pandemic, the global rate of TB-related deaths has increased for the first time in over a decade. We and others have previously shown that a resolved prior or concurrent influenza A virus infection in
MeSH term(s)	Mice ; Animals ; Humans ; Mycobacterium tuberculosis ; SARS-CoV-2 ; Coinfection ; Pandemics ; COVID-19 ; Mice, Transgenic ; Interferon Type I ; Mice, Inbred C57BL
Chemical Substances	K-18 conjugate ; Interferon Type I
Language	English
Publishing date	2023-09-01
Publishing country	Switzerland
Document type	Journal Article ; Research Support, N.I.H., Intramural
ZDB-ID	2606827-8
ISSN	1664-3224 ; 1664-3224
ISSN (online)	1664-3224
ISSN	1664-3224
DOI	10.3389/fimmu.2023.1240419
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Inhibition of Tumor Growth and Metastasis by Newcastle Disease Virus Strain P05 in a Breast Cancer Mouse Model.

Ortega-Rivera, Oscar Antonio / Gallegos-Alcalá, Pamela / Jiménez, Mariela / Quintanar, J Luis / Torres-Juarez, Flor / Rivas-Santiago, Bruno / Del Toro-Arreola, Susana / Salinas, Eva

Journal of breast cancer

2023 Volume 26, Issue 2, Page(s) 186–200

Abstract: Purpose: Conventional therapies and surgery remain the standard treatment for breast cancer. However, combating the eventual development of metastasis is still a challenge. Newcastle disease virus (NDV) is one of the various species of viruses under ... ...

Abstract	Purpose: Conventional therapies and surgery remain the standard treatment for breast cancer. However, combating the eventual development of metastasis is still a challenge. Newcastle disease virus (NDV) is one of the various species of viruses under clinical evaluation as a vector for oncolytic, gene-, and immune-stimulating therapies. The purpose of this study was to evaluate the antitumor activity of a recombinant NDV (rNDV-P05) in a breast cancer murine model. Methods: Tumors were induced by injecting the cellular suspension (4T1 cell line) subcutaneously. The virus strain P05 was applied three times at intervals of seven days, starting seven days after tumor induction, and was completed 21 days later. Determination of tumor weight, spleen index, and lung metastasis were done after sacrificing the mice. Serum levels of interferon (IFN)-α, IFN-γ, tumor necrosis factor (TNF)-α, and TNF-related apoptosis-inducing ligand (TRAIL) were quantified by enzyme-linked immunosorbent assay. CD8+ infiltrated cells were analyzed by immunofluorescence. Results: rNDV-P05 showed a route-of-administration-dependent effect, demonstrating that the systemic administration of the virus significantly reduces the tumor mass and volume, spleen index, and abundance of metastatic clonogenic colonies in lung tissue, and increases the inhibition rate of the tumor. The intratumoral administration of rNDV-P05 was ineffective for all the parameters evaluated. Antitumor and antimetastatic capability of rNDV-P05 is mediated, at least partially, through its immune-stimulatory effect on the upregulation of TNF-α, TRAIL, IFN-α, and IFN-γ, and its ability to recruit CD8+ T cells into tumor tissue. Conclusion: Systemic treatment with rNDV-P05 decreases the tumoral parameters in the breast cancer murine model.
Language	English
Publishing date	2023-02-17
Publishing country	Korea (South)
Document type	Journal Article
ZDB-ID	2559753-X
ISSN	2092-9900 ; 1738-6756
ISSN (online)	2092-9900
ISSN	1738-6756
DOI	10.4048/jbc.2023.26.e9
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6866: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Antimicrobial Peptides-based Nanostructured Delivery Systems: An Approach for Leishmaniasis Treatment.

Rodríguez-Carlos, Adrian / Martinez-Gutierrez, Fidel / Torres-Juarez, Flor / Rivas-Santiago, Bruno

Current pharmaceutical design

2019 Volume 25, Issue 14, Page(s) 1593–1603

Abstract: Background: Leishmaniasis is a major health problem mainly in tropical and subtropical areas worldwide, although in the last decades it has been treated with the use of conventional drugs such as amphotericin, the emergence of multidrug-resistant ... ...

Abstract	Background: Leishmaniasis is a major health problem mainly in tropical and subtropical areas worldwide, although in the last decades it has been treated with the use of conventional drugs such as amphotericin, the emergence of multidrug-resistant strains has raised a warning signal to the public health systems thus a new call for the creation of new leishmanicidal drugs is needed. Methods: The goal of this review was to explore the potential use of antimicrobial peptides-based nanostructured delivery systems as an approach for leishmaniasis treatment. Results: Within these new potential drugs, human host defense peptides (HDP) can be included given their remarkable antimicrobial activity and their outstanding immunomodulatory functions for the therapy of leishmaniasis. Conclusion: Though several approaches have been done using these peptides, new ways for delivering HDPs need to be analyzed, such is the case for nanotechnology.
MeSH term(s)	Antimicrobial Cationic Peptides/administration & dosage ; Drug Delivery Systems ; Humans ; Leishmaniasis/therapy ; Nanostructures
Chemical Substances	Antimicrobial Cationic Peptides
Language	English
Publishing date	2019-07-01
Publishing country	United Arab Emirates
Document type	Journal Article ; Review
ZDB-ID	1304236-1
ISSN	1873-4286 ; 1381-6128
ISSN (online)	1873-4286
ISSN	1381-6128
DOI	10.2174/1381612825666190628152842
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4714: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication.

Baker, Paul J / Bohrer, Andrea C / Castro, Ehydel / Amaral, Eduardo P / Snow-Smith, Maryonne / Torres-Juárez, Flor / Gould, Sydnee T / Queiroz, Artur T L / Fukutani, Eduardo R / Jordan, Cassandra M / Khillan, Jaspal S / Cho, Kyoungin / Barber, Daniel L / Andrade, Bruno B / Johnson, Reed F / Hilligan, Kerry L / Mayer-Barber, Katrin D

bioRxiv : the preprint server for biology

2024

Abstract: SARS-CoV-2 infection leads to vastly divergent clinical outcomes ranging from asymptomatic infection to fatal disease. Co-morbidities, sex, age, host genetics and vaccine status are known to affect disease severity. Yet, how the inflammatory milieu of ... ...

Abstract	SARS-CoV-2 infection leads to vastly divergent clinical outcomes ranging from asymptomatic infection to fatal disease. Co-morbidities, sex, age, host genetics and vaccine status are known to affect disease severity. Yet, how the inflammatory milieu of the lung at the time of SARS-CoV-2 exposure impacts the control of viral replication remains poorly understood. We demonstrate here that immune events in the mouse lung closely preceding SARS-CoV-2 infection significantly impact viral control and we identify key innate immune pathways required to limit viral replication. A diverse set of pulmonary inflammatory stimuli, including resolved antecedent respiratory infections with
Language	English
Publishing date	2024-03-27
Publishing country	United States
Document type	Preprint
DOI	10.1101/2024.03.27.586885
Database	MEDical Literature Analysis and Retrieval System OnLINE

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Retinoic acid induces antimicrobial peptides and cytokines leading to Mycobacterium tuberculosis elimination in airway epithelial cells.

Jacobo-Delgado, Yolanda M / Torres-Juarez, Flor / Rodríguez-Carlos, Adrián / Santos-Mena, Alan / Enciso-Moreno, José E / Rivas-Santiago, Cesar / Diamond, Gill / Rivas-Santiago, Bruno

Peptides

2021 Volume 142, Page(s) 170580

Abstract: Tuberculosis (TB) is the leading cause of death by a single infectious agent, Mycobacterium tuberculosis (Mtb). Alveolar macrophages and respiratory epithelial cells are the first cells exposed to Mtb during the primary infection, once these cells are ... ...

Abstract	Tuberculosis (TB) is the leading cause of death by a single infectious agent, Mycobacterium tuberculosis (Mtb). Alveolar macrophages and respiratory epithelial cells are the first cells exposed to Mtb during the primary infection, once these cells are activated, secrete cytokines and antimicrobial peptides that are associated with the Mtb contention and elimination. Vitamins are micronutrients that function as boosters on the innate immune system, however, is unclear whether they have any protective activity during Mtb infection. Thus, we investigated the role of vitamin A (retinoic acid), vitamin C (ascorbic acid), vitamin D (calcitriol), and vitamin E (alfa-tocopherol) as inductors of molecules related to mycobacterial infection in macrophages and epithelial cells. Our results showed that retinoic acid promotes the expression of pro- and anti-inflammatory molecules such as Thymic stromal lymphopoietin (TSLP), β-defensin-2, IL-1β, CCL20, β-defensin-3, Cathelicidin LL-37, TGF-β, and RNase 7, whereas calcitriol, ascorbic acid, and α-tocopherol lead to an anti-inflammatory response. Treatment of Mtb-infected epithelial cells and macrophage-like cells with the vitamins showed a differential response, where calcitriol reduced Mtb in macrophages, while retinoic acid reduced infection in epithelial cells. Thereby, we propose that a combination of calcitriol and retinoic acid supplementation can drive the immune response, and promotes the Mtb elimination by increasing the expression of antimicrobial peptides and cytokines, while simultaneously modulating inflammation.
MeSH term(s)	Antimicrobial Peptides/pharmacology ; Antineoplastic Agents/pharmacology ; Autophagy ; Bronchi/drug effects ; Bronchi/metabolism ; Bronchi/microbiology ; Bronchi/pathology ; Cells, Cultured ; Cytokines/metabolism ; Epithelial Cells/drug effects ; Epithelial Cells/metabolism ; Epithelial Cells/microbiology ; Epithelial Cells/pathology ; Humans ; Macrophages/drug effects ; Macrophages/metabolism ; Macrophages/microbiology ; Macrophages/pathology ; Mycobacterium tuberculosis/drug effects ; Tretinoin/pharmacology ; Tuberculosis/drug therapy ; Tuberculosis/metabolism ; Tuberculosis/microbiology ; Tuberculosis/pathology
Chemical Substances	Antimicrobial Peptides ; Antineoplastic Agents ; Cytokines ; Tretinoin (5688UTC01R)
Language	English
Publishing date	2021-05-24
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	769028-9
ISSN	1873-5169 ; 0196-9781
ISSN (online)	1873-5169
ISSN	0196-9781
DOI	10.1016/j.peptides.2021.170580
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 1649: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Nicotine associates to intracellular

de Haro-Acosta, Jeny / Jacobo-Delgado, Yolanda M / Rodríguez-Carlos, Adrian / Torres-Juárez, Flor / Araujo, Zaida / Serrano, Carmen J / Gonzalez-Curiel, Irma / Hernández-Pando, Rogelio / Salinas, Eva / Rivas-Santiago, Bruno

Experimental lung research

2021 Volume 47, Issue 10, Page(s) 487–493

Abstract: Tobacco consumption is related to an increased risk to develop tuberculosis. Antimicrobial peptides are essential molecules in the response ... ...

Abstract	Tobacco consumption is related to an increased risk to develop tuberculosis. Antimicrobial peptides are essential molecules in the response to
MeSH term(s)	Antimicrobial Peptides ; Humans ; Macrophages ; Mycobacterium tuberculosis/genetics ; Nicotine/pharmacology ; Tuberculosis
Chemical Substances	Antimicrobial Peptides ; Nicotine (6M3C89ZY6R)
Language	English
Publishing date	2021-11-22
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603791-4
ISSN	1521-0499 ; 0190-2148
ISSN (online)	1521-0499
ISSN	0190-2148
DOI	10.1080/01902148.2021.2006829
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 1568: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article ; Online: Platelets immune response against Mycobacterium tuberculosis infection.

Torres-Juarez, Flor / Trejo-Martínez, Luis A / Layseca-Espinosa, Esther / Leon-Contreras, Juan C / Enciso-Moreno, Jose A / Hernandez-Pando, Rogelio / Rivas-Santiago, Bruno

Microbial pathogenesis

2021 Volume 153, Page(s) 104768

Abstract: Tuberculosis (TB) is the first cause of death by a single infectious agent. Previous reports have highlighted the presence of platelets within Tb granulomas, albeit the immune-associated platelet response to Mycobacterium tuberculosis (Mtb) has not been ... ...

Abstract	Tuberculosis (TB) is the first cause of death by a single infectious agent. Previous reports have highlighted the presence of platelets within Tb granulomas, albeit the immune-associated platelet response to Mycobacterium tuberculosis (Mtb) has not been deeply studied. Our results showed that platelets are recruited into the granuloma in the late stages of tuberculosis. Furthermore, electron-microscopy studies showed that platelets can internalize Mtb and produce host defense peptides (HDPs), such as RNase 7, HBD2 and hPF-4 that bind to the internalized Mtb. Mtb-infected platelets exhibited higher transcription and secretion of IL-1β and TNF-α, whereas IL-10 and IL-6 protein levels decreased. These results suggest that platelets participate in the immune response against Mtb through HDPs and cytokines production.
MeSH term(s)	Blood Platelets ; Cytokines ; Granuloma ; Humans ; Immunity ; Mycobacterium tuberculosis ; Tuberculosis
Chemical Substances	Cytokines
Language	English
Publishing date	2021-01-29
Publishing country	England
Document type	Journal Article
ZDB-ID	632772-2
ISSN	1096-1208 ; 0882-4010
ISSN (online)	1096-1208
ISSN	0882-4010
DOI	10.1016/j.micpath.2021.104768
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 2136: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article: Retinoic acid promotes Mycobacterium tuberculosis elimination inducing antimicrobial peptides and cytokines

Jacobo-Delgado, Yolanda M / Torres-Juarez, Flor / Alonso-Macias, Jacqueline / deHaro-Acosta, Jeny / Rodríguez-Carlos, Adrián / Rivas-Santiago, Cesar / Santos-Mena, Alan / Enciso-Moreno, José E / Marin-Luevano, Sara P / Rivas-Santiago, Bruno

Peptides. 2021 May 19,

2021

Abstract: Tuberculosis (TB) is the leading cause of death by a single infectious agent, Mycobacterium tuberculosis (Mtb). The alveolar macrophages and epithelial cells are the first cells exposed to Mtb during the primary infection, once these cells are activated, ...

Abstract	Tuberculosis (TB) is the leading cause of death by a single infectious agent, Mycobacterium tuberculosis (Mtb). The alveolar macrophages and epithelial cells are the first cells exposed to Mtb during the primary infection, once these cells are activated, secrete soluble factors such as cytokines and antimicrobial peptides that are associated with the Mtb contention and elimination. The vitamins are micronutrients that function as boosters on the innate immune system, nevertheless, is unclear whether they have any protective activity during Mtb infection. Thus, we investigated the role of ascorbic acid, calcitriol (vitamin D), retinoic acid, and alfa-tocopherol as inductors of molecules related to mycobacterial contention in macrophages and epithelial cells. We observed that retinoic acid enhances the Mtb elimination in epithelial cells, thus we decided to explore which molecules were involved. Our results showed that retinoic acid promotes the expression of pro- and anti-inflammatory molecules such as TSLP, β-defensin-2, IL-1β, CCL20, β-defensin-3, Cathelicidin LL-37, TGF-β, and RNase 7, whereas vitamin D, ascorbic acid, and α-tocopherol shows an anti-inflammatory response. Thereby we propose that retinoic acid supplementation drives the immune response and promotes the Mtb elimination by increasing the expression of distinct soluble molecules, whereas modulates the inflammation response to avoid damage to host tissues.
Keywords	Mycobacterium tuberculosis ; alpha-tocopherol ; ascorbic acid ; calcitriol ; cathelicidins ; death ; epithelium ; immune response ; inflammation ; innate immunity ; macrophages ; pathogens ; retinoic acid ; ribonucleases ; tuberculosis
Language	English
Dates of publication	2021-0519
Publishing place	Elsevier Inc.
Document type	Article
Note	NAL-AP-2-clean ; Pre-press version
ZDB-ID	769028-9
ISSN	1873-5169 ; 0196-9781
ISSN (online)	1873-5169
ISSN	0196-9781
DOI	10.1016/j.peptides.2021.170580
Database	NAL-Catalogue (AGRICOLA)

In stock of ZB MED Cologne/Königswinter

Zs.A 1649: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (1.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: The inflammatory microenvironment of the lung at the time of infection governs innate control of SARS-CoV-2 replication

Baker, Paul J / Bohrer, Andrea C / Castro, Ehydel / Amaral, Eduardo P / Snow-Smith, Maryonne / Torres-Juarez, Flor / Gould, Sydnee T / Queiroz, Artur TL / Fukutani, Eduardo R / Jordan, Cassandra M / Khillan, Jaspal S / Cho, Kyoungin / Barber, Daniel L / Andrade, Bruno B / Johnson, Reed F / Hilligan, Kerry L / Mayer-Barber, Katrin D

bioRxiv

Abstract	SARS-CoV-2 infection leads to vastly divergent clinical outcomes ranging from asymptomatic infection to fatal disease. Co-morbidities, sex, age, host genetics and vaccine status are known to affect disease severity. Yet, how the inflammatory milieu of the lung at the time of SARS-CoV-2 exposure impacts the control of viral replication remains poorly understood. We demonstrate here that immune events in the mouse lung closely preceding SARS-CoV-2 infection significantly impact viral control and we identify key innate immune pathways required to limit viral replication. A diverse set of pulmonary inflammatory stimuli, including resolved antecedent respiratory infections with S. aureus or influenza, ongoing pulmonary M. tuberculosis infection, ovalbumin/alum-induced asthma or airway administration of defined TLR ligands and recombinant cytokines, all establish an antiviral state in the lung that restricts SARS-CoV-2 replication upon infection. In addition to antiviral type I interferons, the broadly inducible inflammatory cytokines TNFα and IL-1 precondition the lung for enhanced viral control. Collectively, our work shows that SARS-CoV-2 may benefit from an immunologically quiescent lung microenvironment and suggests that heterogeneity in pulmonary inflammation that precedes or accompanies SARS-CoV-2 exposure may be a significant factor contributing to the population-wide variability in COVID-19 disease outcomes.
Keywords	covid19
Language	English
Publishing date	2024-03-27
Publisher	Cold Spring Harbor Laboratory
Document type	Article ; Online
DOI	10.1101/2024.03.27.586885
Database	COVID19

Full text online

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

Kategorien

Inter-library loan at ZB MED