Article: Electrospun Naringin-Loaded Fibers for Preventing Scar Formation during Wound Healing.
2023 Volume 15, Issue 3
Abstract: Hypertrophic scars (HTSs) are aberrant structures that develop where skin is injured complexly and represent the result of a chronic inflammation as a healing response. To date, there is no satisfactory prevention option for HTSs, which is due to the ... ...
| Abstract | Hypertrophic scars (HTSs) are aberrant structures that develop where skin is injured complexly and represent the result of a chronic inflammation as a healing response. To date, there is no satisfactory prevention option for HTSs, which is due to the complexity of multiple mechanisms behind the formation of these structures. The present work aimed to propose Biofiber (Biodegradable fiber), an advanced textured electrospun dressing, as a suitable solution for HTS formation in complex wounds. Biofiber has been designed as a 3-day long-term treatment to protect the healing environment and enhance wound care practices. Its textured matrix consists of homogeneous and well-interconnected Poly-L-lactide-co-poly-ε-caprolactone (PLA-PCL) electrospun fibers (size 3.825 ± 1.12 µm) loaded with Naringin (NG, 2.0% |
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| Language | English |
| Publishing date | 2023-02-23 |
| Publishing country | Switzerland |
| Document type | Journal Article |
| ZDB-ID | 2527217-2 |
| ISSN | 1999-4923 |
| ISSN | 1999-4923 |
| DOI | 10.3390/pharmaceutics15030747 |
| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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