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  1. Article: Navigating the complexity of skull base osteomyelitis: a case study and comprehensive review.

    Horache, Kenza / Jidal, Manal / Kettani, Najwa El / Fikri, Meriem / Jiddane, Mohamed / Touarsa, Firdaous

    Journal of surgical case reports

    2024  Volume 2024, Issue 5, Page(s) rjae282

    Abstract: Skull base osteomyelitis is a rare and life-threatening infection of the skull base, commonly seen in elderly diabetic patients as a result of otogenic or paranasal infection. The diagnosis is based on a series of arguments, including a high clinical ... ...

    Abstract Skull base osteomyelitis is a rare and life-threatening infection of the skull base, commonly seen in elderly diabetic patients as a result of otogenic or paranasal infection. The diagnosis is based on a series of arguments, including a high clinical suspicion, imaging findings, negative biopsies for malignancy, and microbiological isolation. Complications, including abscess formation and vascular involvement, mandate a multidisciplinary treatment approach, primarily involving broad-spectrum antibiotics and surgical debridement, but the prognosis is usually poor. Herein, we describe the case of a 55-year-old male, who 15 years prior, underwent radiation therapy for nasopharyngeal carcinoma. He presented with an infection of the skull base with extensive bone erosion accompanied by an uncommon complication; an intra clival abscess. Despite aggressive antibiotic therapy, the patient ultimately succumbed to septic shock.
    Language English
    Publishing date 2024-05-02
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjae282
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: A rare case of bilateral en plaque meningioma presenting as a bilateral exophthalmos. A case report.

    Lahlou, Chaimae / Naggar, Amine / Hadj Hssain, Ihssane / Touarsa, Firdaous / Fikri, Meryem / Jidane, Mohamed

    SAGE open medical case reports

    2024  Volume 12, Page(s) 2050313X241252340

    Abstract: En plaque meningioma is a rare type of meningioma characterized by an infiltrative nature, sheet-like growth, and at times invading the bone. We report here a case of en plaque meningioma. The patient was a 66-year-old woman presenting with headache and ... ...

    Abstract En plaque meningioma is a rare type of meningioma characterized by an infiltrative nature, sheet-like growth, and at times invading the bone. We report here a case of en plaque meningioma. The patient was a 66-year-old woman presenting with headache and painful bilateral proptosis. Cerebral magnetic resonance imaging revealed a bilateral en plaque meningioma showed as a bilateral hyperostotic of greater wing sphenoid bone associated with bilateral thickening and enhancement of the dura in the anterior temporal area and the retroclival region invading bilaterally the cavernous sinus, the prechiasmatic portion of the optic nerve, and the lateral rectus muscle of the orbit through the superior orbital fissure causing bilateral exophthalmia. Due to invasion of the cavernous sinus and the orbital apex, a subtotal but extensive removal combined with bony decompression of the cranial nerves at the superior orbital fissure and optic canal followed by adjuvant radiotherapy frequently produces good functional and cosmetic results, and over a 3-year period, follow-up magnetic resonance imaging scans showed no obvious signs of recurrence.
    Language English
    Publishing date 2024-05-06
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X241252340
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Septo-optic dysplasia PLUS syndrome in a 23 years old patient: A case report.

    Harras, Yahya El / Choayb, Safaa / Kettani, Najwa Ech Cherif / Fikri, Meryem / Jiddane, Mohamed / Touarsa, Firdaous

    Radiology case reports

    2023  Volume 18, Issue 9, Page(s) 2982–2986

    Abstract: Septo-optic dysplasia (SOD) is a rare malformation defined by septum pellucidum abnormalities and hypoplasia of the optic nerves and chiasm. It can be associated with cortical development malformations such as schizencephaly, which is then called septo- ... ...

    Abstract Septo-optic dysplasia (SOD) is a rare malformation defined by septum pellucidum abnormalities and hypoplasia of the optic nerves and chiasm. It can be associated with cortical development malformations such as schizencephaly, which is then called septo-optic dysplasia plus. It usually manifests at birth, although it may not be diagnosed until childhood, or rarely, adolescence. We report the case of a 23 years old patient, with a history of epilepsy since early childhood never labeled, which was diagnosed with SOD-PLUS with brain MRI in our department.
    Language English
    Publishing date 2023-06-20
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2023.05.057
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Brain MRI abnormalities associated with amyotrophic lateral sclerosis: A case illustration.

    Choayb, Safaa / Harras, Yahya El / Fikri, Meriem / Kettani, Najoua Ech-Cherif El / Jiddane, Mohamed / Touarsa, Firdaous

    Radiology case reports

    2023  Volume 18, Issue 11, Page(s) 3972–3974

    Abstract: Amyotrophic lateral sclerosis is a progressive neurodegenerative pathology. It involves both upper and lower motor neurons, leading to their degeneration. Lower motor neurons can be detected with an electromyogram, but the detection of upper motor neuron ...

    Abstract Amyotrophic lateral sclerosis is a progressive neurodegenerative pathology. It involves both upper and lower motor neurons, leading to their degeneration. Lower motor neurons can be detected with an electromyogram, but the detection of upper motor neuron dysfunction may be more accurate using MRI. We present the case of a 64-year-old woman with amyotrophic lateral sclerosis, presenting the motor band sign and the bright tongue sign on MRI.
    Language English
    Publishing date 2023-08-31
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2023.08.053
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Acute headache and seizures in psychiatric patient revealing atypical location of a ruptured dermoid cyst.

    Berrada, Kenza / Bougrin, Imad / Ouali, Ibtissam El / Fikri, Meryem / Jiddane, Mohamed / Touarsa, Firdaous

    Radiology case reports

    2023  Volume 19, Issue 3, Page(s) 1040–1045

    Abstract: Intracranial dermoid cysts are rare slow-growing cystic lesions. They are frequently extra-axial, intra-axial localization is very rare. These benign congenital ectodermal inclusions cysts have a rare risk of rupture. Ruptured dermoid cysts can manifest ... ...

    Abstract Intracranial dermoid cysts are rare slow-growing cystic lesions. They are frequently extra-axial, intra-axial localization is very rare. These benign congenital ectodermal inclusions cysts have a rare risk of rupture. Ruptured dermoid cysts can manifest with headache, epilepsy seizure, cerebral infarction, meningitis, and hydrocephaly. Neuroimaging features are quite characteristic. We report a case of a 30-year-old male who presented to the emergency room with subacute-onset headaches. CT scan and MRI show a ruptured intracranial dermoid cyst.
    Language English
    Publishing date 2023-12-22
    Publishing country Netherlands
    Document type Case Reports
    ZDB-ID 2406300-9
    ISSN 1930-0433
    ISSN 1930-0433
    DOI 10.1016/j.radcr.2023.11.068
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: The dangers of "Chasing the dragon": a fatal case of heroin-induced leukoencephalopathy.

    Bourekba, Iliass / Halfi, Ismail / Ech Cherif Kettani, Najwa / Fikri, Meryem / Jidane, Mohamed / Touarsa, Firdaous

    BJR case reports

    2023  Volume 10, Issue 1, Page(s) uaad004

    Abstract: Heroin-induced leukoencephalopathy (HLE) is a rare toxic encephalopathy associated primarily with heroin inhalation, commonly referred to as "chasing the dragon." This study presents a clinical case of a 27-year-old polydrug user diagnosed with HLE ... ...

    Abstract Heroin-induced leukoencephalopathy (HLE) is a rare toxic encephalopathy associated primarily with heroin inhalation, commonly referred to as "chasing the dragon." This study presents a clinical case of a 27-year-old polydrug user diagnosed with HLE during hospitalization for rapidly progressive flaccid tetraplegia and aphasia. The clinical manifestations encompassed cerebellar and bulbar dysfunction, coupled with motor impairment and altered consciousness. Based on the clinical data and MRI results, HLE was identified as the most likely cause. This article aims to provide insights into the clinical and radiological aspects of HLE, emphasizing the diagnostic significance of radiological findings. The gold standard examination for diagnosis is MRI, crucial due to the difficulties in obtaining histological confirmation for this rare condition.
    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Case Reports
    ISSN 2055-7159
    ISSN (online) 2055-7159
    DOI 10.1093/bjrcr/uaad004
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Fulminant Susac syndrome-a rare cause of coma: The history of the fatal course in a young man.

    Andour, Hajar / Rostoum, Soufiane / Regragui, Yassine / Fikri, Meriem / Jiddane, Mohamed / Touarsa, Firdaous

    SAGE open medical case reports

    2023  Volume 11, Page(s) 2050313X221149826

    Abstract: Susac syndrome is a rare microangiopathy of indeterminate etiology, presumably autoimmune, characterized by a triad of encephalopathy, sensorineural hearing loss, and branch retinal artery occlusions occurring predominantly in women. The onset and ... ...

    Abstract Susac syndrome is a rare microangiopathy of indeterminate etiology, presumably autoimmune, characterized by a triad of encephalopathy, sensorineural hearing loss, and branch retinal artery occlusions occurring predominantly in women. The onset and progression patterns are multiple, mainly of three modes. Fulminant evolution is exceptional, rarely reported across literature. We report through this case a Susac syndrome in a young man in whom evolution was fatal. Magnetic resonance imaging is essential to raise the diagnosis and for follow-up, with almost pathognomonic findings, all the more useful as the clinical triad is usually incomplete and as the encephalopathy is the most limiting of the symptoms.
    Language English
    Publishing date 2023-02-02
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X221149826
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article: Spontaneous clival meningocele.

    El Ouali, Ibtissam / Behyamet, Onka / Elkettani, Najwa / Fikri, Meriem / Jiddane, Mohamed / Touarsa, Firdaous

    SAGE open medical case reports

    2022  Volume 10, Page(s) 2050313X221117334

    Abstract: The occipital bone is an uncommon location for meningoceles protrusion. This condition occurs generally after a severe traumatism or surgical procedure. However, in some rare cases, the herniation can happen spontaneously. Nontraumatic clival ... ...

    Abstract The occipital bone is an uncommon location for meningoceles protrusion. This condition occurs generally after a severe traumatism or surgical procedure. However, in some rare cases, the herniation can happen spontaneously. Nontraumatic clival meningoceles present an extremely rare entity and correspond to a herniating pachymeningeal collection containing cerebrospinal fluid through a zone of fragility in the clivus. Clinical presentation ranges from simple headache or rhinorrhea to severe complications such as recurrent bacterial meningitis or nerve compression. Computed tomography provides an analysis of the bone and magnetic resonance imaging provides a superior contrast resolution, helping to distinguish among the various types of clival lesions. We report the case of a young woman with a long history of idiopathic intracranial hypertension, who presented with a worsening headache. Magnetic resonance imaging confirmed a clival meningocele without other complications and the patient was put under medical surveillance.
    Language English
    Publishing date 2022-08-06
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X221117334
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article: Incidental optic nerve sheath arachnoid cyst: A rare case finding with literature review.

    Touarsa, Firdaous / El Ouali, Ibtissam / Elkettani, Najwa / Fikri, Meriem / Jiddane, Mohamed

    SAGE open medical case reports

    2022  Volume 10, Page(s) 2050313X221113261

    Abstract: Arachnoid cysts are the most common benign cystic abnormalities formed due to congenital splitting of the arachnoid layer. They comprise 1% of intracranial masses, and the orbital location is even more rarely reported in history especially in the ... ...

    Abstract Arachnoid cysts are the most common benign cystic abnormalities formed due to congenital splitting of the arachnoid layer. They comprise 1% of intracranial masses, and the orbital location is even more rarely reported in history especially in the pediatric population. They might be discovered as an asymptomatic finding on imaging performed for a concomitant condition or, in most reported cases, as a result of ophthalmic impairment. They can be isolated or associated with gliomas, neurofibromas, empty sella syndrome, and frontotemporal porencephalic cysts. Computed tomography scan shows a non-enhancing liquid cystic lesion, and magnetic resonance imaging remains the best assessment tool confirming the similarity of the fluid to cerebrospinal fluid and evaluating the optic nerves. Herein, we report the case of an incidental discovery of an intraorbital arachnoid cyst on magnetic resonance imaging in a 53-year-old woman with a history of epilepsy. No treatment was performed as the cystic formation was asymptomatic.
    Language English
    Publishing date 2022-07-22
    Publishing country England
    Document type Case Reports
    ZDB-ID 2736953-5
    ISSN 2050-313X
    ISSN 2050-313X
    DOI 10.1177/2050313X221113261
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Bifocal Intracanial Rosai-Dorfman Disease Mimicking Lymphoplasmacyte-Rich Meningioma: Diagnostic Pitfalls About a Case Report.

    Ouazzani, Hafsa El / Touarsa, Firdaous / Iraqui Houssaini, Zaynab / Hakkou, Mahdi / Elouadghiri, Mohammed Yasaad / Ouhabi, Abdessamad / Jiddane, Mohamed / Zouaidia, Fouad / Cherradi, Nadia

    Clinical medicine insights. Case reports

    2023  Volume 16, Page(s) 11795476231172354

    Abstract: Rosai-Dorfman disease (RDD) is a clonal histiocytic proliferation characterized by large S100 positive histiocytes with variable emperipolesis. Extranodal locations were confirmed with the central nervous system or the meninges involvement in less than 5% ...

    Abstract Rosai-Dorfman disease (RDD) is a clonal histiocytic proliferation characterized by large S100 positive histiocytes with variable emperipolesis. Extranodal locations were confirmed with the central nervous system or the meninges involvement in less than 5% of cases, which is marked as a significant differential diagnosis of meningiomas in radiological and intra-operative pathological examination. Histopathology and immunohistochemistry are the keys to definitive diagnosis. We present a case of bifocal Rosai-Dorfman disease in a 26-year-old man, mimicking Lymphoplasmacyte-rich Meningioma. This case allows us to demonstrate the diagnosis pitfalls encountered in this localization.
    Language English
    Publishing date 2023-05-12
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2580498-4
    ISSN 1179-5476
    ISSN 1179-5476
    DOI 10.1177/11795476231172354
    Database MEDical Literature Analysis and Retrieval System OnLINE

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