LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 47

Search options

  1. Article: A Rare Case Report of Granular Cell Tumour of the Abdominal Wall and a Review of the Literature.

    Mangan, Simone H / Ng, Jessica Y / Townend, Philip

    Cureus

    2024  Volume 16, Issue 2, Page(s) e54399

    Abstract: Granular cell tumours (GCTs) are rare soft tissue tumours of neural origin. They have been reported in multiple anatomical sites. However, only 14 cases worldwide have been reported arising from the abdominal wall. While they can clinically manifest in a ...

    Abstract Granular cell tumours (GCTs) are rare soft tissue tumours of neural origin. They have been reported in multiple anatomical sites. However, only 14 cases worldwide have been reported arising from the abdominal wall. While they can clinically manifest in a variety of ways, often they present as a small, slow-growing nodule with benign features. They can, however, be malignant, and in rare cases, they have been reported to metastasise. Here, we present a case of a rare abdominal wall GCT, which was managed with local excision. The purpose of this paper is to report the patient's clinical history, presentation, and surgical management, as well as to review the current literature to highlight the existence of this rare entity and the possibility that this may occur and should be considered a differential diagnosis in clinical practice.
    Language English
    Publishing date 2024-02-18
    Publishing country United States
    Document type Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.54399
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  2. Article ; Online: Open sandwich mesh repair of a large recurrent incisional flank hernia.

    Tran, Elisa / Summers, Zara / Parker, David / Townend, Philip

    BMJ case reports

    2024  Volume 17, Issue 4

    MeSH term(s) Humans ; Surgical Mesh ; Incisional Hernia/surgery ; Herniorrhaphy/methods ; Recurrence ; Male ; Female ; Hernia, Ventral/surgery ; Aged
    Language English
    Publishing date 2024-04-25
    Publishing country England
    Document type Case Reports ; Journal Article
    ISSN 1757-790X
    ISSN (online) 1757-790X
    DOI 10.1136/bcr-2023-259361
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  3. Article: Current management of gastro-oesophageal reflux disease-treatment costs, safety profile, and effectiveness: a narrative review.

    Lata, Tahmina / Trautman, Jodie / Townend, Philip / Wilson, Robert B

    Gastroenterology report

    2023  Volume 11, Page(s) goad008

    Abstract: Background: The purpose of this study was to review the current management of gastro-oesophageal reflux disease (GORD), including treatment costs, safety profile and effectiveness.: Methods: A literature review was performed of randomized-controlled ... ...

    Abstract Background: The purpose of this study was to review the current management of gastro-oesophageal reflux disease (GORD), including treatment costs, safety profile and effectiveness.
    Methods: A literature review was performed of randomized-controlled trials, systematic reviews, Cochrane reports and National/Societal guidelines of the medical, endoscopic and surgical management of GORD. Proton pump inhibitor (PPI) prescribing patterns and expenditure were reviewed in different countries, including Australia, Canada, New Zealand, UK and USA.
    Results: Proton pump inhibitors (PPIs) are primarily indicated for control of GORD, Helicobacter pylori eradication (combined with antibiotics), preventing NSAID-induced gastrointestinal bleeding and treating peptic ulcer disease. There is widespread overprescribing of PPIs in Western and Eastern nations in terms of indication and duration, with substantial expense for national health providers. Despite a favourable short-term safety profile, there are observational associations of adverse effects with long-term PPIs. These include nutrient malabsorption, enteric infections and cardiovascular events. The prevalence of PPI use makes their long-term safety profile clinically relevant. Cost-benefit, symptom control and quality-of-life outcomes favour laparoscopic fundoplication rather than chronic PPI treatment. Laparoscopic fundoplication in long-term management of PPI-responsive GORD is supported by SAGES, NICE and ACG, and PPI-refractory GORD by AGA and SAGES guidelines. The importance of establishing a definitive diagnosis prior to invasive management is emphasized, especially in PPI-refractory heartburn.
    Conclusions: We examined evidence-based guidelines for PPI prescribing and deprescribing in primary care and hospital settings and the need for PPI stewardship and education of health professionals. This narrative review presents the advantages and disadvantages of surgical, endoscopic and medical management of GORD, which may assist in shared decision making and treatment choice in individual patients.This paper was presented (GS020) at the 88th RACS Annual Scientific Conference, 6-10 May, 2019.
    Language English
    Publishing date 2023-04-18
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 2710871-5
    ISSN 2052-0034
    ISSN 2052-0034
    DOI 10.1093/gastro/goad008
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  4. Article ; Online: Association between neutrophil-lymphocyte ratio and lymph node metastasis in gastric cancer: A meta-analysis.

    Kotecha, Krishna / Singla, Animesh / Townend, Philip / Merrett, Neil

    Medicine

    2022  Volume 101, Issue 25, Page(s) e29300

    Abstract: Introduction and aim: The prognostic role of neutrophil to lymphocyte ratio (NLR) has been explored extensively in the literature. The aim of this meta-analysis was to evaluate the link between NLR and lymph node metastasis in gastric cancer. A method ... ...

    Abstract Introduction and aim: The prognostic role of neutrophil to lymphocyte ratio (NLR) has been explored extensively in the literature. The aim of this meta-analysis was to evaluate the link between NLR and lymph node metastasis in gastric cancer. A method for increasing specificity and sensitivity of pre-treatment staging has implications on treatment algorithms and survival.
    Search strategy: The relevant databases were searched as per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses flowchart. After selection, 12 full text articles that met the inclusion criteria were included for quantitative analysis. 2 × 2 squares were generated using lymph node positive/negative, and NLR high/low data. The effect size for each study was calculated using the DerSimonian-Laird random effects model. P values were calculated using the chi-square method. Finally publication bias was evaluated. All statistics were calculated using R Studio.
    Results: Meta-analysis showed a 1.90 times (odds ratio, with 95% CI 1.52-2.38) increase in risk of positive lymph node status with high neutrophil to lymphocyte ratio. This has significant implications for cancer screening and staging, as NLR is a highly reproducible, cost-effective, and widely available prognostic factor for gastric cancer patients. Additionally, high or low NLR values may have implications for management pathways. Patients with lymph node metastasis can be offered neoadjuvant chemotherapy, avoiding salvage therapy in the form of adjuvant chemoradiotherapy, which is poorly tolerated.
    Conclusion: This meta-analysis shows an association between NLR and positive lymph node status in gastric cancer patients with implications for staging, as well as preoperative personalisation of therapy.
    MeSH term(s) Humans ; Lymphatic Metastasis/pathology ; Lymphocytes/pathology ; Neutrophils/pathology ; Prognosis ; Retrospective Studies ; Stomach Neoplasms/pathology ; Stomach Neoplasms/therapy
    Language English
    Publishing date 2022-06-24
    Publishing country United States
    Document type Journal Article ; Meta-Analysis
    ZDB-ID 80184-7
    ISSN 1536-5964 ; 0025-7974
    ISSN (online) 1536-5964
    ISSN 0025-7974
    DOI 10.1097/MD.0000000000029300
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  5. Article: An unusual case of abdominal compartment syndrome from a massive faecaloma.

    Chuang, Fred Jui-Ju / Lim, Aaron Er-Wynn / Cooper, Michelle Louise / Townend, Phillip / Parker, David James

    Journal of surgical case reports

    2022  Volume 2022, Issue 8, Page(s) rjac348

    Abstract: Severe constipation is a frequent presentation but progression into a life-threatening acute compartment syndrome (ACS) is few and far between. This case highlights the typical physiological manifestations of ACS and the immediate benefits of correcting ... ...

    Abstract Severe constipation is a frequent presentation but progression into a life-threatening acute compartment syndrome (ACS) is few and far between. This case highlights the typical physiological manifestations of ACS and the immediate benefits of correcting these physiological imbalances through the disimpaction of a massive faecaloma. Furthermore, in adult patients with a history of colonic dysmotility, adult Hirschsprung's disease should be considered.
    Language English
    Publishing date 2022-08-06
    Publishing country England
    Document type Case Reports
    ZDB-ID 2580919-2
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjac348
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  6. Article: Temperance, Father Mathew, and the Irish clergy.

    Townend, P

    New hibernia review = Iris eireannach nua

    1999  Volume 3, Issue 1, Page(s) 111–122

    MeSH term(s) Alcoholic Beverages/history ; Clergy/history ; Drinking Behavior ; History, 19th Century ; Ireland/ethnology ; Public Health/history ; Social Behavior/history ; Social Change/history ; Social Conditions/history ; Temperance/history
    Language English
    Publishing date 1999
    Publishing country United States
    Document type Historical Article ; Journal Article
    ISSN 1092-3977
    ISSN 1092-3977
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  7. Article: Giant hepatic haemangioma rupture in a patient on direct oral anticoagulant therapy.

    Nguyen, Marie / Lim, Aaron E / Jeyarajan, Eshwarshanker / Koh, Mary-Ann / Ng, Andrew / Townend, Phillip

    Journal of surgical case reports

    2021  Volume 2021, Issue 1, Page(s) rjaa523

    Abstract: Rupture of a liver haemangioma is extremely rare, with less than 100 cases reported in the literature. This is the first case known to date reporting a rupture occurring with direct oral anticoagulant therapy. A 76-year-old woman presented with acute ... ...

    Abstract Rupture of a liver haemangioma is extremely rare, with less than 100 cases reported in the literature. This is the first case known to date reporting a rupture occurring with direct oral anticoagulant therapy. A 76-year-old woman presented with acute abdominal pain and syncope in the context of commencing apixaban 4 weeks prior. Abdominal computed tomography and angiography demonstrated a large heterogenous mass in the left liver lobe with contrast blush suggestive of a bleeding tumour. Urgent transcatheter arterial embolization successfully ceased haemorrhage. Due to persistent compressive symptoms, a left lateral hepatectomy was performed. CD34 immunostaining of the tissue revealed variably sized vessels, which was consistent with a ruptured giant hepatic haemangioma. Our case substantiates the limited available literature regarding ruptured haemangiomas. Combined with previous case reports, this report will significantly contribute to our understanding of the risk factors, diagnosis and surgical indications for ruptured hepatic haemangiomas.
    Language English
    Publishing date 2021-01-29
    Publishing country England
    Document type Case Reports
    ISSN 2042-8812
    ISSN 2042-8812
    DOI 10.1093/jscr/rjaa523
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  8. Article ; Online: Rare differential of right iliac fossa pain.

    Watson, Matthew / Townend, Phil / Chua, Terence C / Pincott, Stuart J

    ANZ journal of surgery

    2017  Volume 87, Issue 3, Page(s) 208–209

    Language English
    Publishing date 2017
    Publishing country Australia
    Document type Letter
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.13755
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  9. Article: 'Treatment of Class II malocclusions with removable appliances. 1. Case assessment'.

    Townend, P

    British dental journal

    1990  Volume 168, Issue 7, Page(s) 278

    MeSH term(s) Humans ; Malocclusion/therapy ; Malocclusion, Angle Class II/therapy ; Orthodontic Appliances, Removable ; Tooth Movement Techniques/methods
    Language English
    Publishing date 1990-04-07
    Publishing country England
    Document type Letter ; Comment
    ZDB-ID 218090-x
    ISSN 1476-5373 ; 0007-0610
    ISSN (online) 1476-5373
    ISSN 0007-0610
    DOI 10.1038/sj.bdj.4807179
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

  10. Article ; Online: Modified Longmire procedure: a novel approach to bile duct injury repair.

    Kotecha, Krishna / Kaushal, Devesh / Low, Willy / Townend, Philip / Das, Amitabha / Apostolou, Christos / Merrett, Neil

    ANZ journal of surgery

    2018  Volume 89, Issue 11, Page(s) E554–E555

    MeSH term(s) Anastomotic Leak/etiology ; Anastomotic Leak/surgery ; Cholangiopancreatography, Endoscopic Retrograde/methods ; Cholecystectomy, Laparoscopic/adverse effects ; Common Bile Duct/diagnostic imaging ; Common Bile Duct/injuries ; Common Bile Duct/pathology ; Female ; Humans ; Iatrogenic Disease ; Laparotomy/methods ; Laparotomy/trends ; Middle Aged ; Postoperative Complications/etiology ; Reoperation/trends ; Treatment Outcome
    Language English
    Publishing date 2018-10-22
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 2050749-5
    ISSN 1445-2197 ; 1445-1433 ; 0004-8682
    ISSN (online) 1445-2197
    ISSN 1445-1433 ; 0004-8682
    DOI 10.1111/ans.14901
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

To top