Article ; Online: Reduction in Maintenance Immunosuppression in Kidney Transplant Recipients With Stable Donor-Derived Cell-Free DNA Measurements: A Case Series.
2022 Volume 55, Issue 1, Page(s) 93–97
Abstract: Personalization of maintenance immunosuppression in kidney transplant recipients has long remained a goal in the transplant community. The recent addition of donor-derived cell-free DNA assays to detect allograft rejection and monitor allograft health ... ...
| Abstract | Personalization of maintenance immunosuppression in kidney transplant recipients has long remained a goal in the transplant community. The recent addition of donor-derived cell-free DNA assays to detect allograft rejection and monitor allograft health may permit for reductions in maintenance immunosuppression in recipients with stable levels. Herein, we described 5 patients with stable donor-derived cell-free DNA levels who underwent reduction in maintenance immunosuppression without precipitation of clinical rejection, proteinuria, or de novo donor specific antibody formation. |
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| MeSH term(s) | Humans ; Immunosuppressive Agents ; Kidney Transplantation ; Immunosuppression Therapy ; Tissue Donors ; Transplantation, Homologous ; Graft Rejection ; Transplant Recipients | |||||
| Chemical Substances | Immunosuppressive Agents | |||||
| Language | English | |||||
| Publishing date | 2022-12-29 | |||||
| Publishing country | United States | |||||
| Document type | Journal Article | |||||
| ZDB-ID | 82046-5 | |||||
| ISSN | 1873-2623 ; 0041-1345 | |||||
| ISSN (online) | 1873-2623 | |||||
| ISSN | 0041-1345 | |||||
| DOI | 10.1016/j.transproceed.2022.12.003 | |||||
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| Database | MEDical Literature Analysis and Retrieval System OnLINE |
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