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  1. AU="Tran, Diep"
  2. AU="Ahmad, Kafeel"
  3. AU=Gor?kov Lev P.
  4. AU="Scott, Carol E"
  5. AU="Siewiera, Jacek"
  6. AU="Clutterbuck, Elizabeth A"
  7. AU="Shin, Dong Jin"
  8. AU="Talapuhan, Wulan"
  9. AU=Wang Cheng AU=Wang Cheng
  10. AU="Bélanger, Richard E"
  11. AU="Bárcena-Flores, Luis"
  12. AU="Bhargava, Tanvi"
  13. AU="Markus Hafner"
  14. AU="Simon, Jessica E"
  15. AU="Watson, Erin"
  16. AU=Cox Fionnuala
  17. AU="Rana, Dev Yash"
  18. AU="Negreira Caamaño, Martín"
  19. AU="Johan C. Karremans"
  20. AU="Elmutaz Shaikho Elhaj Mohammed"
  21. AU="Amjad, Muhammad"
  22. AU="Rolf D Kortmann"
  23. AU="Jelena Stanojević"
  24. AU="Rafael Sáez-Jiménez"
  25. AU="Carlile, Catherine R"
  26. AU="Husain, Waleed"
  27. AU="Casanelia, S"
  28. AU="Ireland, D. G."
  29. AU=Sargon Peter J.

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  1. Artikel ; Online: Social Risk Groups in Patients With Diabetes With Differing Eye Care Utilization and Vision Outcomes.

    Cai, Cindy X / Han, Dingfen / Tran, Diep / Moreno, Jose Amezcua / Zeger, Scott L / Crews, Deidra C

    Translational vision science & technology

    2024  Band 13, Heft 3, Seite(n) 13

    Abstract: Purpose: To evaluate whether latent class analysis on social determinants of health (SDoH) data can identify social risk groups that differ by adverse SDoH and vision outcomes in patients with diabetes.: Methods: This was a prospective cohort study ... ...

    Abstract Purpose: To evaluate whether latent class analysis on social determinants of health (SDoH) data can identify social risk groups that differ by adverse SDoH and vision outcomes in patients with diabetes.
    Methods: This was a prospective cohort study of adults ≥18 years with diabetes who completed a SDoH survey. Latent class analysis was used to cluster patients into social risk groups. The association of social risk group and severity of diabetic retinopathy, history of lapses in diabetic retinopathy care, and visual acuity was evaluated.
    Results: A total of 1006 participants were included. The three social risk groups differed by sociodemographic characteristics. The average age was 65, 60, and 54 in Groups 1, 2, and 3 respectively. Most (51%) patients in group 1 were non-Hispanic White, 66% in group 2 were non-Hispanic Black, and 80% in group 3 were Hispanic. Group 1 had the lowest burden of adverse SDoH per person (average 3.6), group 2 had 8.2, and group 3 had 10.5. In general, group 1 lacked diabetic retinopathy knowledge, group 2 had financial insecurity and difficulties with transportation, and group 3 had financial insecurity and did not have health insurance. Social risk group was associated with a history of lapses in diabetic retinopathy care, and presenting with worse vision.
    Conclusions and translational relevance: We identified distinct social risk groups among patients seeking care for diabetic retinopathy that differed by social needs, eye care utilization, and vision. Identifying these groups and their specific needs can help guide interventions to effectively address adverse SDoH and improve eye care utilization and vision outcomes among patients with diabetes.
    Mesh-Begriff(e) Adult ; Humans ; Diabetic Retinopathy/epidemiology ; Diabetic Retinopathy/therapy ; Prospective Studies ; Vision, Ocular ; Visual Acuity ; Diabetes Mellitus/epidemiology ; Diabetes Mellitus/therapy
    Sprache Englisch
    Erscheinungsdatum 2024-03-18
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2674602-5
    ISSN 2164-2591 ; 2164-2591
    ISSN (online) 2164-2591
    ISSN 2164-2591
    DOI 10.1167/tvst.13.3.13
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  2. Artikel ; Online: Place, Race, and Lapses in Diabetic Retinopathy Care.

    Tang, Tina / Tran, Diep / Han, Dingfen / Zeger, Scott L / Crews, Deidra C / Cai, Cindy X

    JAMA ophthalmology

    2024  

    Sprache Englisch
    Erscheinungsdatum 2024-04-25
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 2701705-9
    ISSN 2168-6173 ; 2168-6165
    ISSN (online) 2168-6173
    ISSN 2168-6165
    DOI 10.1001/jamaophthalmol.2024.0974
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  3. Artikel ; Online: Benzodiazepines for pediatric epilepsies and their risks in a cohort within the French health care data.

    Auvin, Stéphane / Guillo, Sylvie / de Rycke, Yann / Tran, Diep / Tubach, Florence

    Epilepsia

    2024  Band 65, Heft 4, Seite(n) 900–908

    Abstract: Objective: The management of antiseizure treatment in patients with epilepsy relies on the benefit-risk ratio. Data on antiseizure medication (ASM) use in children are limited. We described antiseizure medication use in children with epilepsy (CwE) in ... ...

    Abstract Objective: The management of antiseizure treatment in patients with epilepsy relies on the benefit-risk ratio. Data on antiseizure medication (ASM) use in children are limited. We described antiseizure medication use in children with epilepsy (CwE) in France, with a focus on the chronic use of benzodiazepines and related implications.
    Methods: We conducted a 5-year cohort study from January 2012, using data from the French national health care data system (Système National des Données de Santé). We included CwE identified through International Classification of Diseases, 10th Revision codes and medications from January 2012 to December 2015 and followed them until December 2016. We described ASMs and assessed whether the risk of initiating a polytherapy after a bitherapy depends on whether benzodiazepine was included in the bitherapy.
    Results: We identified 62 885 CwE. Valproate was the most reimbursed ASM (40%), followed by lamotrigine (17.6%), levetiracetam (9.3%), clobazam (6.1%), and carbamazepine (5.8%). Prescriptions were initiated at the hospital in 74.5% of CwE. We observed a decrease in the number of CwE with at least one benzodiazepine reimbursement from 15.3% in 2013 to 10.1% in 2016 (p < .0001). The prevalence of CwE with levetiracetam reimbursements increased, whereas that of CwE with valproate decreased. A switch from a bitherapy to a polytherapy was more likely when the bitherapy included a benzodiazepine (subdistribution hazard ratio [sHR] = 1.20 [1.03-1.39]).
    Significance: The prevalence of CwE with at least one benzodiazepine reimbursement decreased during the study period. Benzodiazepines were associated with an increased use of subsequent ASM polytherapy.
    Mesh-Begriff(e) Humans ; Child ; Benzodiazepines/therapeutic use ; Valproic Acid ; Levetiracetam ; Cohort Studies ; Epilepsy/drug therapy ; Epilepsy/epidemiology ; Delivery of Health Care ; Anticonvulsants/adverse effects
    Chemische Substanzen Benzodiazepines (12794-10-4) ; Valproic Acid (614OI1Z5WI) ; Levetiracetam (44YRR34555) ; Anticonvulsants
    Sprache Englisch
    Erscheinungsdatum 2024-02-14
    Erscheinungsland United States
    Dokumenttyp Journal Article
    ZDB-ID 216382-2
    ISSN 1528-1167 ; 0013-9580
    ISSN (online) 1528-1167
    ISSN 0013-9580
    DOI 10.1111/epi.17906
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  4. Artikel: Progress towards health equity in Vietnam: evidence from nationwide official health statistics, 2010-2020.

    Feng, Yikai / Tuan, Tran Diep / Shi, Junyi / Li, Zhuo / Maimaitiming, Mailikezhati / Jin, Yinzi / Zheng, Zhijie

    BMJ global health

    2024  Band 9, Heft 3

    Abstract: Introduction: One of the ultimate goals of strengthening the health system is to achieve health equity. Vietnam is considered one of the 'fast-track countries' to achieve the health-related Millennium Development Goals, but research on its equity ... ...

    Abstract Introduction: One of the ultimate goals of strengthening the health system is to achieve health equity. Vietnam is considered one of the 'fast-track countries' to achieve the health-related Millennium Development Goals, but research on its equity strategies remains inadequate.
    Methods: Using Vietnamese official health statistics, we investigated inequity in four dimensions including health resources, service delivery, service utilisation and residents' health status from the perspectives of income levels, poverty rates and subnational regions. The Slope Index of Inequality, concentration curve/Concentration Index, absolute difference and Theil Index were used.
    Results: Four indicators showed 'pro-poor' inequality in health resources, including the per capita health budget, per capita health personnel, per capita health personnel at the community level and per capita hospital beds at the community level, while provincial hospital beds showed 'pro-rich' inequality. Two health service delivery indicators (delivery of antenatal care ≥3 times and proportion of community health service centres with medical doctors) show 'pro-rich' inequality, although two health status indicators, mortality and malnutrition rates for children under five, showed 'pro-poor' inequality. The Northern Midlands and Mountain Areas, and the Central Highlands were disadvantaged regarding service delivery and health status. Intraregional differences were the main factors contributing to the inequalities in delivery of antenatal care ≥3 times, provincial hospital beds and percentage of community health centres with medical doctors, with the Red River Delta and the South East region experiencing the greatest inequalities.
    Conclusion: The overall level of health equity in Vietnam has increased over the past decade, although inequality in health service delivery has hindered progress towards health equity based on income, poverty and subnational regions. Targeted policies need to be introduced to reduce inequities relating to the health workforce and service delivery capacity.
    Mesh-Begriff(e) Child ; Humans ; Female ; Pregnancy ; Socioeconomic Factors ; Health Equity ; Vietnam/epidemiology ; Public Health ; Healthcare Disparities
    Sprache Englisch
    Erscheinungsdatum 2024-03-18
    Erscheinungsland England
    Dokumenttyp Journal Article
    ISSN 2059-7908
    ISSN 2059-7908
    DOI 10.1136/bmjgh-2023-014739
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  5. Buch ; Online ; Dissertation / Habilitation: Karst and cave development and groundwater resources of Dong Van Karst Plateau, Northern Vietnam

    Tran, Diep Anh [Verfasser] / Goldscheider, Nico [Akademischer Betreuer] / Neumann, Thomas [Akademischer Betreuer]

    2023  

    Verfasserangabe Diep Anh Tran ; Nico Goldscheider, Thomas Neumann
    Schlagwörter Geowissenschaften ; Earth Sciences
    Thema/Rubrik (Code) sg550
    Sprache Englisch
    Verlag KIT-Bibliothek
    Erscheinungsort Karlsruhe
    Dokumenttyp Buch ; Online ; Dissertation / Habilitation
    Datenquelle Digitale Dissertationen im Internet

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  6. Artikel ; Online: The Impact of Social Determinants of Health on Eye Care Utilization in a National Sample of People with Diabetes.

    Taccheri, Claudia / Jordan, Jalin / Tran, Diep / Wang, Jiangxia / Han, Dingfen / Varadaraj, Varshini / Crews, Deidra C / Cai, Cindy X

    Ophthalmology

    2023  Band 130, Heft 10, Seite(n) 1037–1045

    Abstract: Purpose: To evaluate the association of social determinants of health (SDoH) with eye care utilization among people with diabetes mellitus using the 2013-2017 National Health Interview Survey (NHIS).: Design: Retrospective cross-sectional study.: ... ...

    Abstract Purpose: To evaluate the association of social determinants of health (SDoH) with eye care utilization among people with diabetes mellitus using the 2013-2017 National Health Interview Survey (NHIS).
    Design: Retrospective cross-sectional study.
    Participants: Participants ≥ 18 years of age with self-reported diabetes.
    Methods: The SDoH in the following domains were used: (1) economic stability; (2) neighborhood, physical environment, and social cohesion; (3) community and social context; (4) food environment; (5) education; and (6) health care system. An aggregate SDoH score was calculated and divided into quartiles, with Q4 representing those with the highest adverse SDoH burden. Survey-weighted multivariable logistic regression models evaluated the association of SDoH quartile with eye care utilization in the preceding 12 months. A linear trend test was conducted. Domain-specific mean SDoH scores were calculated, and the performance of domain-specific models was compared using area under the curve (AUC).
    Main outcome measure: Eye care utilization in the preceding 12 months.
    Results: Of 20 807 adults with diabetes, 43% had not used eye care. Greater adverse SDoH burden was associated with decrements in odds of eye care utilization (P < 0.001 for trend). Participants in the highest quartile of adverse SDoH burden (Q4) had a 58% lower odds (odds ratio [OR], 0.42; 95% confidence interval [CI], 0.37-0.47) of eye care utilization than those in Q1. The domain-specific model using economic stability had the highest performing AUC (0.63; 95% CI, 0.62-0.64).
    Conclusions: Among a national sample of people with diabetes, adverse SDoH were associated with decreased eye care utilization. Evaluating and intervening upon the effects of adverse SDoH may be a means by which to improve eye care utilization and prevent vision loss.
    Financial disclosure(s): Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
    Mesh-Begriff(e) Adult ; Humans ; Social Determinants of Health ; Cross-Sectional Studies ; Retrospective Studies ; Diabetes Mellitus/therapy ; Educational Status
    Sprache Englisch
    Erscheinungsdatum 2023-06-15
    Erscheinungsland United States
    Dokumenttyp Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't
    ZDB-ID 392083-5
    ISSN 1549-4713 ; 0161-6420
    ISSN (online) 1549-4713
    ISSN 0161-6420
    DOI 10.1016/j.ophtha.2023.06.007
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  7. Artikel ; Online: Dietary fibre in hypertension and cardiovascular disease management

    Andrew N. Reynolds / Ashley Akerman / Shiristi Kumar / Huyen Tran Diep Pham / Sean Coffey / Jim Mann

    BMC Medicine, Vol 20, Iss 1, Pp 1-

    systematic review and meta-analyses

    2022  Band 9

    Abstract: Abstract Background Higher dietary fibre intakes are associated with a reduced risk of developing cardiovascular disease (CVD), and increasing intake has been shown to reduce blood pressure and other cardiometabolic risk factors. The extent to which ... ...

    Abstract Abstract Background Higher dietary fibre intakes are associated with a reduced risk of developing cardiovascular disease (CVD), and increasing intake has been shown to reduce blood pressure and other cardiometabolic risk factors. The extent to which dietary fibre can further reduce risk for those with CVD and treated with cardioprotective drugs has not been clearly established. We have examined the evidence for dietary fibre as adjunct therapy in those with CVD or hypertension. Methods Ovid MEDLINE, Embase, PubMed, and CENTRAL were searched to June 2021. Prospective observational studies reporting on fibre intakes and mortality in those with pre-existing CVD and controlled trials of increasing fibre intakes on cardiometabolic risk factors in those with CVD or hypertension were eligible. Outcomes were mortality (studies) and cardiometabolic risk factors (trials). Data synthesis was with random effects and dose response. Certainty of evidence was assessed using GRADE. Results Three prospective studies including 7469 adults with CVD, and 12 trials of 878 adults with CVD or hypertension were identified. Moderate certainty evidence indicates reduced all-cause mortality (relative risk, RR0.75 (95% confidence interval, CI 0.58–0.97)) when comparing higher with lower fibre intakes. Low certainty evidence from trials of adults with cardiovascular disease indicates increasing fibre intakes reduced total (mean difference, MD − 0.42 mmol/L (95%CI − 0.78 to − 0.05) and low-density lipoprotein (LDL) cholesterol (MD − 0.47mmol/L (95%CI − 0.85 to − 0.10)). High certainty evidence from trials of adults with hypertension indicates increasing fibre intakes reduces systolic (MD 4.3 mmHg (95% CI 2.2 to 5.8)) and diastolic blood pressure (MD 3.1 mmHg (95% CI 1.7 to 4.4)). Moderate and low certainty evidence indicated improvements in fasting blood glucose (MD 0.48 mmol/L (− 0.91 to − 0.05)) and LDL cholesterol (MD 0.29 mmol/L (95% CI 0.17 to 0.40)). Benefits were observed irrespective of cardioprotective drug use. Conclusions These ...
    Schlagwörter Coronary artery disease ; Hypertension ; Meta-analysis ; Epidemiology ; Medical education ; Medicine ; R
    Thema/Rubrik (Code) 610
    Sprache Englisch
    Erscheinungsdatum 2022-04-01T00:00:00Z
    Verlag BMC
    Dokumenttyp Artikel ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Buch ; Online: Saturated fat and trans-fat intakes and their replacement with other macronutrients

    Reynolds, Andrew N. / Hodson, Leanne / De Souza, Russell / Tran Diep Pham, Huyen / Vlietstra, Lara / Mann, Jim

    a systematic review and meta-analysis of prospective observational studies

    2022  

    Abstract: vi, 154 p. ...

    Abstract vi, 154 p.
    Schlagwörter Systematic Review ; Meta-Analysis ; Trans Fatty Acids ; Fatty Acids ; Cardiovascular Diseases ; Stroke ; Coronary Disease
    Sprache Englisch
    Verlag World Health Organization
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Health Disparities in Lapses in Diabetic Retinopathy Care.

    Cai, Cindy X / Tran, Diep / Tang, Tina / Liou, Wilson / Harrigian, Keith / Scott, Emily / Nagy, Paul / Kharrazi, Hadi / Crews, Deidra C / Zeger, Scott L

    Ophthalmology science

    2023  Band 3, Heft 3, Seite(n) 100295

    Abstract: Objective: To develop a novel methodology to identify lapses in diabetic retinopathy care in electronic health records (EHRs) and evaluate health disparities by race and ethnicity.: Design: Retrospective cohort study.: Subjects: Adult patients ... ...

    Abstract Objective: To develop a novel methodology to identify lapses in diabetic retinopathy care in electronic health records (EHRs) and evaluate health disparities by race and ethnicity.
    Design: Retrospective cohort study.
    Subjects: Adult patients with diabetes mellitus who were evaluated at the Wilmer Eye Institute from January 1, 2013 to April 2, 2022.
    Methods: The methodology to identify lapses in care first identified diabetic retinopathy screening or treatment visits and then compared the providers' recommended follow-up timeframe with the patient's actual time to next encounter. The association of race and ethnicity with odds of lapses in care was evaluated using a mixed-effects logistic regression model controlling for age, sex, insurance, severity of diabetic retinopathy, presence of other retinal disorders, and glaucoma.
    Main outcome measures: Lapses in diabetic retinopathy care.
    Results: The methodology to identify diabetic retinopathy-related visits had a 95.0% (95% confidence interval, 93.0-96.6) sensitivity and 98.8% (98.1-99.3) specificity as compared with a gold standard grader. The methodology resulted in a 97.3% (96.2-98.4) sensitivity and 98.1% (97.3-98.9) specificity for detecting a follow-up recommendation, with an average error of -0.05 (-0.31 to 0.21) weeks in extracting the precise timeframe. A total of 39 561 patients with 91 104 office visits were included in the analysis. The average age was 61.4 years. More than 3 (77.6%) in 4 patients had a lapse in care. In multivariable analysis, non-Hispanic Black patients had 1.24 (1.19-1.30) odds and Hispanic patients had 1.26 (1.13-1.40) odds of ever having a lapse in care compared with non-Hispanic White patients (
    Conclusions: We have developed a reliable methodology for identifying lapses in diabetic retinopathy care that is tailored to a provider's recommended follow-up. Using this approach, we find that 3 in 4 patients experience a lapse in diabetic retinopathy care and that these rates are higher among non-Hispanic Black and Hispanic patients. Deploying this methodology in the EHR is one potential means by which to identify and mitigate lapses in critical ophthalmic care in patients with diabetes.
    Financial disclosures: Proprietary or commercial disclosure may be found after the references.
    Sprache Englisch
    Erscheinungsdatum 2023-03-04
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ISSN 2666-9145
    ISSN (online) 2666-9145
    DOI 10.1016/j.xops.2023.100295
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  10. Artikel: Secondary Mediastinal Bleeding Caused by Parathyroid Adenocarcinoma: A Case Report.

    Hoang Phan, Hiep / Thanh Do, Cong / Ngoc Tran, Luong / Giang Nguyen, Son / Ngoc Tran, Diep / Tien Nguyen, Son / Dinh Le, Tuan

    Clinical medicine insights. Case reports

    2023  Band 16, Seite(n) 11795476231190538

    Abstract: Introduction: The clinical picture of parathyroid tumors is mainly related to hypercalcemia such as kidney stones and bone and muscle pain. However, spontaneous cervical hemorrhage due to parathyroidoma bleeding is rare with clinical manifestations of ... ...

    Abstract Introduction: The clinical picture of parathyroid tumors is mainly related to hypercalcemia such as kidney stones and bone and muscle pain. However, spontaneous cervical hemorrhage due to parathyroidoma bleeding is rare with clinical manifestations of the painful swelling and bruising of the neck accompanied by dysphagia and dyspnea.
    Case presentation: We report a case of a 71-year-old female patient who presented with acute cervical swelling and extensive bleeding spreading from the neck to the abdomen and 2 flanks. Investigation of patients revealed increased parathyroid hormone levels and hypercalcemia. The neck ultrasound showed the thyroid nodules in 2 lobes, and goiter plongeant on the right. Computed tomography scan images showed a hematoma spreading from the right side of the neck to the mediastinum.
    Result: The patient required emergency surgery due to dyspnea and hemodynamic instability. The preoperative diagnosis was cervical bleeding with the likely cause being thyroid nodule rupture. However, during the surgery, the bleeding source was determined to be the right parathyroid tumor located deeply below the superior mediastinum. The patient's histopathological result of the tumor is parathyroid adenocarcinoma.
    Conclusion: From our experience, the hemorrhage from parathyroid tumor should be considered as a cause of acute neck bleeding when no history of trauma or surgery is identified. Post-surgery histopathological analyses of the tumor are very important to detect parathyroid adenocarcinoma.
    Sprache Englisch
    Erscheinungsdatum 2023-08-03
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2580498-4
    ISSN 1179-5476
    ISSN 1179-5476
    DOI 10.1177/11795476231190538
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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