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Article ; Online: SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence.

Gutierrez, J Ignacio / Brittingham, Gregory P / Karadeniz, Yonca / Tran, Kathleen D / Dutta, Arnob / Holehouse, Alex S / Peterson, Craig L / Holt, Liam J

eLife

2022 Volume 11

Abstract: It is increasingly appreciated that intracellular pH changes are important biological signals. This motivates the elucidation of molecular mechanisms of pH sensing. We determined that a nucleocytoplasmic pH oscillation was required for the ... ...

Abstract	It is increasingly appreciated that intracellular pH changes are important biological signals. This motivates the elucidation of molecular mechanisms of pH sensing. We determined that a nucleocytoplasmic pH oscillation was required for the transcriptional response to carbon starvation in
MeSH term(s)	Carbon ; Chromatin Assembly and Disassembly ; Chromosomal Proteins, Non-Histone/metabolism ; Hydrogen-Ion Concentration ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Transcription Factors/metabolism
Chemical Substances	Chromosomal Proteins, Non-Histone ; Saccharomyces cerevisiae Proteins ; Transcription Factors ; Carbon (7440-44-0)
Language	English
Publishing date	2022-02-07
Publishing country	England
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	2687154-3
ISSN	2050-084X ; 2050-084X
ISSN (online)	2050-084X
ISSN	2050-084X
DOI	10.7554/eLife.70344
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Article ; Online: Scleredema diabeticorum.

Tran, Kathleen / Boyd, Kevin P / Robinson, Maria R / Whitlow, Michael

Dermatology online journal

2013 Volume 19, Issue 12, Page(s) 20718

Abstract: We present a case of scleredema with a leonine facies in a 56-year-old man with a history of poorly controlled diabetes mellitus. The patient initially presented with erythematous, edematous papules and plaques on the face, neck, and upper back. ...

Abstract	We present a case of scleredema with a leonine facies in a 56-year-old man with a history of poorly controlled diabetes mellitus. The patient initially presented with erythematous, edematous papules and plaques on the face, neck, and upper back.
MeSH term(s)	Diabetes Complications/pathology ; Diabetes Mellitus ; Face ; Humans ; Male ; Middle Aged ; Scleredema Adultorum/pathology ; Skin/pathology
Language	English
Publishing date	2013-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ISSN	1087-2108
ISSN (online)	1087-2108
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Article ; Online: Graft-vs-host disease.

Tran, Kathleen / Kaplan, Jennifer / Kamino, Hideko / Latkowski, Jo-Ann

Dermatology online journal

2013 Volume 19, Issue 12, Page(s) 20710

Abstract: We present a case of chronic graft-versus-host disease in a 61-year-old woman with a history of B-cell chronic lymphocytic leukemia that was treated with an allogeneic bone marrow transplant from an unrelated donor. The patient initially presented with ... ...

Abstract	We present a case of chronic graft-versus-host disease in a 61-year-old woman with a history of B-cell chronic lymphocytic leukemia that was treated with an allogeneic bone marrow transplant from an unrelated donor. The patient initially presented with erythematous patches on the trunk and extremities that evolved into reticulated, hyperpigmented patches and lichenified plaques.
MeSH term(s)	Bone Marrow Transplantation/adverse effects ; Female ; Graft vs Host Disease/immunology ; Graft vs Host Disease/pathology ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell/therapy ; Middle Aged ; Skin Diseases/immunology ; Skin Diseases/pathology ; Transplantation, Homologous
Language	English
Publishing date	2013-12-16
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2026239-5
ISSN	1087-2108 ; 1087-2108
ISSN (online)	1087-2108
ISSN	1087-2108
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Article ; Online: Spiradenomas.

Tran, Kathleen / DeFelice, Taylor / Robinson, Maria / Patel, Rishi / Sanchez, Miguel

Dermatology online journal

2012 Volume 18, Issue 12, Page(s) 15

Abstract: We report a 52-year-old man with a one-year history of multiple, firm, skin-colored nodules on the vertex of the scalp. Histopathologic examination was consistent with a spiradenoma, which is a rare, benign adnexal tumor of controversial histogenesis. ... ...

Abstract	We report a 52-year-old man with a one-year history of multiple, firm, skin-colored nodules on the vertex of the scalp. Histopathologic examination was consistent with a spiradenoma, which is a rare, benign adnexal tumor of controversial histogenesis. Multiple spiradenomas may arise in association with Brooke-Spiegler syndrome, which is an autosomal dominant condition of multiple cyclindromas, trichoeptheliomas, and cyclindromas.
MeSH term(s)	Adenoma, Sweat Gland/pathology ; Humans ; Male ; Middle Aged ; Scalp/pathology ; Sweat Gland Neoplasms/pathology
Language	English
Publishing date	2012-12
Publishing country	United States
Document type	Case Reports ; Journal Article
ISSN	1087-2108
ISSN (online)	1087-2108
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Article ; Online: White fibrous papulosis of the neck.

Schaffer, Panta Rouhani / Tran, Kathleen / Kaplan, Jennifer / Patel, Rishi / Kamino, Hideko / Ramachandran, Sarika / Franks, Andrew G

Dermatology online journal

2014 Volume 20, Issue 12

Abstract: We present a 76-year old woman with a five-year history of asymptomatic, white papules that were grouped on the lateral and posterior aspects of the neck, inferior axillae, and central mid-back. The histopathologic findings showed thickened collagen ... ...

Abstract	We present a 76-year old woman with a five-year history of asymptomatic, white papules that were grouped on the lateral and posterior aspects of the neck, inferior axillae, and central mid-back. The histopathologic findings showed thickened collagen bundles. A diagnosis of white fibrous papulosis of the neck was made, which is believed to be a manifestation of intrinsic aging. There are no treatments for white fibrous papulosis of the neck. One hypothesized approach is the application of a topical anti-oxidant to reduce free-radical induced aging.
MeSH term(s)	Aged ; Female ; Humans ; Neck ; Skin Aging/pathology ; Skin Diseases, Papulosquamous/pathology
Language	English
Publishing date	2014-12-16
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2026239-5
ISSN	1087-2108 ; 1087-2108
ISSN (online)	1087-2108
ISSN	1087-2108
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Article ; Online: Peripheral vasculopathy associated with psychostimulant treatment in children with attention-deficit/hyperactivity disorder.

Yu, Zheya Jenny / Parker-Kotler, Caroline / Tran, Kathleen / Weller, Ronald A / Weller, Elizabeth B

Current psychiatry reports

2010 Volume 12, Issue 2, Page(s) 111–115

Abstract: Psychostimulants (methylphenidate and amphetamine salt) are the pharmacologic treatment of choice for children with attention-deficit/hyperactivity disorder. However, psychostimulants have been linked to a variety of vascular problems, including ... ...

Abstract	Psychostimulants (methylphenidate and amphetamine salt) are the pharmacologic treatment of choice for children with attention-deficit/hyperactivity disorder. However, psychostimulants have been linked to a variety of vascular problems, including peripheral vasculopathy. This article describes four boys with attention-deficit/hyperactivity disorder who developed vasculopathy during treatment with psychostimulants.
MeSH term(s)	Adolescent ; Amphetamine/adverse effects ; Attention Deficit Disorder with Hyperactivity/drug therapy ; Central Nervous System Stimulants/adverse effects ; Child ; Humans ; Male ; Methylphenidate/adverse effects ; Peripheral Vascular Diseases/chemically induced ; Severity of Illness Index ; Treatment Outcome
Chemical Substances	Central Nervous System Stimulants ; Methylphenidate (207ZZ9QZ49) ; Amphetamine (CK833KGX7E)
Language	English
Publishing date	2010-04-28
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2055376-6
ISSN	1535-1645 ; 1523-3812
ISSN (online)	1535-1645
ISSN	1523-3812
DOI	10.1007/s11920-010-0093-y
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Article ; Online: Photolichenoid plaques with associated vitiliginous pigmentary changes.

Tran, Kathleen / Hartman, Rachael / Tzu, Julia / Meehan, Shane / Sanders, Scott E / Pomeranz, Miriam Keltz / Sanchez, Miguel

Dermatology online journal

2011 Volume 17, Issue 10, Page(s) 13

Abstract: A 49-year-old man with advanced HIV/AIDS on anti-retroviral therapy (HAART) and trimethoprim-sulfamethoxazole (TMP-SMX) presented with a several-month history of pruritic, erythematous, lichenified papules that coalesced into hyperkeratotic plaques on ... ...

Abstract	A 49-year-old man with advanced HIV/AIDS on anti-retroviral therapy (HAART) and trimethoprim-sulfamethoxazole (TMP-SMX) presented with a several-month history of pruritic, erythematous, lichenified papules that coalesced into hyperkeratotic plaques on the trunk and extremities in a sun-exposed distribution. He shortly thereafter developed a progressive depigmentation over more than 80 percent of his body surface area. A biopsy specimen of an erythematous plaque on the trunk showed a superficial and mid-dermal infiltrate of lymphocytes with eosinophils, most consistent with either chronic lichenoid drug eruption or atypical lymphoproliferative disorder (ACLD) of HIV. The patient's lichenoid skin disease has persisted despite discontinuation of TMP-SMX, although it has improved partially with administration of topical glucocorticoids and acitretin. His depigmentation has continued to progress. We discuss the overlapping diagnostic entities which may be comprised by this patient's clinical disease, and highlight a unique presentation of the complex interaction between HIV infection and the skin.
MeSH term(s)	Acitretin/adverse effects ; Acitretin/therapeutic use ; Acquired Immunodeficiency Syndrome/complications ; Anti-HIV Agents/adverse effects ; Anti-HIV Agents/therapeutic use ; Antiretroviral Therapy, Highly Active ; Bacteremia/complications ; Diagnosis, Differential ; Disease Progression ; Eczema/diagnosis ; Erythema/complications ; Erythema/diagnosis ; Erythema/pathology ; Glucocorticoids/therapeutic use ; Herpes Simplex/complications ; Humans ; Lichenoid Eruptions/diagnosis ; Lichenoid Eruptions/pathology ; Lymphoma, T-Cell, Cutaneous/diagnosis ; Lymphoproliferative Disorders/diagnosis ; Male ; Middle Aged ; Photosensitivity Disorders/complications ; Photosensitivity Disorders/diagnosis ; Photosensitivity Disorders/drug therapy ; Photosensitivity Disorders/pathology ; Pseudolymphoma/diagnosis ; Trimethoprim, Sulfamethoxazole Drug Combination/adverse effects ; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use ; Ultraviolet Therapy ; Vitiligo/complications ; Vitiligo/diagnosis ; Vitiligo/pathology ; Vitiligo/therapy
Chemical Substances	Anti-HIV Agents ; Glucocorticoids ; Trimethoprim, Sulfamethoxazole Drug Combination (8064-90-2) ; Acitretin (LCH760E9T7)
Language	English
Publishing date	2011-10-15
Publishing country	United States
Document type	Case Reports ; Journal Article
ZDB-ID	2026239-5
ISSN	1087-2108 ; 1087-2108
ISSN (online)	1087-2108
ISSN	1087-2108
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Article ; Online: Mobile teledermatology in the developing world: implications of a feasibility study on 30 Egyptian patients with common skin diseases.

Tran, Kathleen / Ayad, Mohamed / Weinberg, Jennifer / Cherng, Augustin / Chowdhury, Mridul / Monir, Saadeddin / El Hariri, Mohamed / Kovarik, Carrie

Journal of the American Academy of Dermatology

2011 Volume 64, Issue 2, Page(s) 302–309

Abstract: Background: The expansion of store-and-forward teledermatology into underserved regions of the world has long been hampered by the requirement for computers with Internet connectivity. To our knowledge, this study is one of the first to demonstrate the ... ...

Abstract	Background: The expansion of store-and-forward teledermatology into underserved regions of the world has long been hampered by the requirement for computers with Internet connectivity. To our knowledge, this study is one of the first to demonstrate the feasibility of teledermatology using newer-generation mobile telephones with specialized software and wireless connectivity to overcome this requirement in a developing country. Objective: We sought to demonstrate that mobile telephones may be used on the African continent to submit both patient history and clinical photographs wirelessly to remote expert dermatologists, and to assess whether these data are diagnostically reliable. Methods: Thirty patients with common skin diseases in Cairo, Egypt, were given a diagnosis by face-to-face consultation. They were then given a diagnosis independently by local senior dermatologists using teleconsultation with a software-enabled mobile telephone containing a 5-megapixel camera. Diagnostic concordance rates between face-to-face and teleconsultation were tabulated. Results: Diagnostic agreement between face-to-face consultation and the two local senior dermatologists performing independent evaluation by teleconsultation was achieved in 23 of 30 (77%) and in 22 of 30 (73%) cases, respectively, with a global mean of 75%. Limitations: Limited sample size and interobserver variability are limitations. Conclusion: Mobile teledermatology is a technically feasible and diagnostically reliable method of amplifying access to dermatologic expertise in poorer regions of the globe where access to computers with Internet connectivity is unreliable or insufficient.
MeSH term(s)	Cell Phone ; Dermatology/methods ; Developing Countries ; Egypt ; Feasibility Studies ; Humans ; Internet ; Observer Variation ; Reproducibility of Results ; Skin Diseases/diagnosis ; Telemedicine/methods
Language	English
Publishing date	2011-02
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	603641-7
ISSN	1097-6787 ; 0190-9622
ISSN (online)	1097-6787
ISSN	0190-9622
DOI	10.1016/j.jaad.2010.01.010
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Article ; Online: Genetic Mapping of a new

Siders, Jamie L / Bieser, Kayla L / Hamill, Danielle R / Acosta, Erika C / Alexander, Olivia K / Ali, Humza I / Anderson, Micah J / Arrasmith, Hayden R / Azam, Mustafa / Beeman, Nikki J / Beydoun, Hassan / Bishop, Lauren J / Blair, Morgan D / Bletch, Brianna / Bline, Heather R / Brown, Jennifer C / Burns, Kelly M / Calagua, Karina C / Chafin, Lexie /

Christy, William Ah / Ciamacco, Carlyn / Cizauskas, Hannah / Colwell, Caitlyn M / Courtright, Abigail R / Diaz Alavez, Lucero / Ecret, Rayne Is / Edriss, Fatima / Ellerbrock, Taylor G / Ellis, Madison M / Extine, Erica M / Feldman, Eric / Fickenworth, Luke J / Goeller, Caroline M / Grogg, Alexis S / Hernandez, Yailine / Hershner, Abigail / Jauss, Megan M / Jimenez Garcia, Leyre / Franks, Katey E / Kazubski, Ethan T / Landis, Emily R / Langub, Jon / Lassek, Tia N / Le, Triet C / Lee, Julia M / Levine, Daniel P / Lightfoot, Phoebe J / Love, Natasha / Maalhagh-Fard, Ali / Maguire, Colin / McGinnis, Brynna E / Mehta, Bhargavi V / Melendrez, Veronica / Mena, Zimri E / Mendell, Seth / Montiel-Garcia, Petra / Murry, Autumn S / Newland, Riley A / Nobles, Ryan M / Patel, Neha / Patil, Yashodhara / Pfister, Cassidy L / Ramage, Victoria / Ray, Mya R / Rodrigues, Joseph / Rodriquez, Victoria C / Romero, Yara / Scott, Alexandra M / Shaba, Nicholas / Sieg, Samantha / Silva, Kayla / Singh, Sahiba / Spargo, Aleksandria J / Spitnale, Savanna J / Sweeden, Nicole / Tague, Logan / Tavernini, Breanna M / Tran, Kathleen / Tungol, Liselle / Vestal, Kylie A / Wetherbee, Amber / Wright, Kayla M / Yeager, Anthony T / Zahid, Rehab / Kagey, Jacob D

microPublication biology

2021 Volume 2021

Abstract: Genetic screens provide a mechanism to identify genes involved with different cellular and organismal processes. Using a Flp/FRT screen in ... ...

Abstract	Genetic screens provide a mechanism to identify genes involved with different cellular and organismal processes. Using a Flp/FRT screen in the
Language	English
Publishing date	2021-04-08
Publishing country	United States
Document type	Journal Article
ISSN	2578-9430
ISSN (online)	2578-9430
DOI	10.17912/micropub.biology.000383
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