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Article ; Online: SWI/SNF senses carbon starvation with a pH-sensitive low-complexity sequence.

Gutierrez, J Ignacio / Brittingham, Gregory P / Karadeniz, Yonca / Tran, Kathleen D / Dutta, Arnob / Holehouse, Alex S / Peterson, Craig L / Holt, Liam J

eLife

2022  Volume 11

Abstract: It is increasingly appreciated that intracellular pH changes are important biological signals. This motivates the elucidation of molecular mechanisms of pH sensing. We determined that a nucleocytoplasmic pH oscillation was required for the ... ...

Abstract It is increasingly appreciated that intracellular pH changes are important biological signals. This motivates the elucidation of molecular mechanisms of pH sensing. We determined that a nucleocytoplasmic pH oscillation was required for the transcriptional response to carbon starvation in
MeSH term(s) Carbon ; Chromatin Assembly and Disassembly ; Chromosomal Proteins, Non-Histone/metabolism ; Hydrogen-Ion Concentration ; Saccharomyces cerevisiae/genetics ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Transcription Factors/metabolism
Chemical Substances Chromosomal Proteins, Non-Histone ; Saccharomyces cerevisiae Proteins ; Transcription Factors ; Carbon (7440-44-0)
Language English
Publishing date 2022-02-07
Publishing country England
Document type Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID 2687154-3
ISSN 2050-084X ; 2050-084X
ISSN (online) 2050-084X
ISSN 2050-084X
DOI 10.7554/eLife.70344
Database MEDical Literature Analysis and Retrieval System OnLINE

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