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  1. Article ; Online: Defining and Refining the Role of Adjuvant Chemoradiation for Biliary Tract Cancers After SWOG 0809.

    Acidi, Belkacem / Tran Cao, Hop S

    Annals of surgical oncology

    2024  

    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Editorial
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-024-15323-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: High volume transplant experience is beneficial but not mandatory for the performance of complex liver resections.

    Ayabe, Reed / Vauthey, Jean-Nicolas / Tran Cao, Hop S

    Hepatobiliary surgery and nutrition

    2022  Volume 11, Issue 6, Page(s) 879–881

    Language English
    Publishing date 2022-12-13
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-22-447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Robot-assisted liver resection: the real benefit so far.

    Ayabe, Reed I / Azimuddin, Ahad / Tran Cao, Hop S

    Langenbeck's archives of surgery

    2022  Volume 407, Issue 5, Page(s) 1779–1787

    Abstract: Background: Minimally invasive liver resection is associated with lower perioperative morbidity and shorter hospital stay. However, the added benefit of the robotic platform over conventional laparoscopy is a matter of ongoing investigation.: Purpose!# ...

    Abstract Background: Minimally invasive liver resection is associated with lower perioperative morbidity and shorter hospital stay. However, the added benefit of the robotic platform over conventional laparoscopy is a matter of ongoing investigation.
    Purpose: The purpose of this narrative review is to provide an up-to-date and balanced evaluation of the benefits and shortcomings of robotic liver surgery for the modern hepatobiliary surgeon.
    Conclusions: Advantages of a robotic approach to liver resection include a shortened learning curve, the ability to complete more extensive or complex minimally invasive operations, and integrated fluorescence guidance. However, the robotic platform remains limited by a paucity of parenchymal transection devices, complete lack of haptic feedback, and added operating time associated with docking and instrument exchange. Like laparoscopic hepatectomy, robotic hepatectomy may provide patients with more rapid recovery and a shorter hospital stay, which can help offset the substantial costs of robot acquisition and maintenance. The oncologic outcomes of robotic hepatectomy appear to be equivalent to laparoscopic and open hepatectomy for appropriately selected patients.
    MeSH term(s) Hepatectomy ; Humans ; Laparoscopy ; Length of Stay ; Liver ; Liver Neoplasms/surgery ; Robotic Surgical Procedures ; Robotics
    Language English
    Publishing date 2022-04-30
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 1423681-3
    ISSN 1435-2451 ; 1435-2443
    ISSN (online) 1435-2451
    ISSN 1435-2443
    DOI 10.1007/s00423-022-02523-7
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Insurance Disparities in Access to Robotic Surgery for Colorectal Cancer.

    Childers, Christopher P / Uppal, Abhineet / Tillman, Matthew / Chang, George J / Tran Cao, Hop S

    Annals of surgical oncology

    2023  Volume 30, Issue 6, Page(s) 3560–3568

    Abstract: Background: The use of the robotic approach is increasing for colorectal cancer operations, but the added cost of the platform has the potential to introduce challenges in its dissemination. We hypothesized that adoption of the robot is introducing new ... ...

    Abstract Background: The use of the robotic approach is increasing for colorectal cancer operations, but the added cost of the platform has the potential to introduce challenges in its dissemination. We hypothesized that adoption of the robot is introducing new disparities in access to minimally invasive surgery (MIS) for colorectal cancer, especially across patient insurance groups.
    Methods: This cross-sectional study analyzed surgical cases of stage I-III colorectal cancer from the National Cancer Database (NCDB) between 2010 and 2019. The primary outcome was surgical approach (robotic, laparoscopic, or the composite "MIS"). The predictor was a patient's primary payor. Potential confounders included sociodemographics, tumor characteristics, and the facility. Hierarchical multivariable models were generated, and sensitivity analyses were performed.
    Results: For colorectal cancer operations, the MIS approach increased from 39% in 2010 to 73% in 2019, driven predominantly by an increase in the robotic approach from 2 to 24%. For laparoscopy, the size of the disparity between patients with Private insurance and Medicaid shrank from 11% (2010) to 4% (2019), whereas this disparity increased for the robotic approach from 1% (2010) to 5% (2019). On adjusted analysis, patients with Medicaid (odds ratio [OR] 0.86 [CI 0.79-0.95]) and the Uninsured (OR 0.67 [CI 0.56-0.79]) had lower odds of receiving a robotic operation than those with Private insurance in 2019. This disparity remained consistent across five sensitivity analyses.
    Conclusions: As the field of colorectal cancer surgery shifts away from laparoscopy and toward robotics, new inequities across patient insurance are emerging. Proactive efforts are needed to ensure all patients benefit from a minimally invasive approach.
    MeSH term(s) United States ; Humans ; Robotic Surgical Procedures ; Cross-Sectional Studies ; Colorectal Neoplasms/surgery ; Laparoscopy ; Insurance ; Retrospective Studies
    Language English
    Publishing date 2023-03-21
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-13354-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Great Debates: Neoadjuvant Therapy Should be Routinely Given for High-Risk Cholangiocarcinoma.

    Tran Cao, Hop S / Ferrone, Cristina / Maithel, Shishir K / Rocha, Flavio G

    Annals of surgical oncology

    2023  Volume 30, Issue 13, Page(s) 7960–7965

    MeSH term(s) Humans ; Neoadjuvant Therapy ; Cholangiocarcinoma/pathology ; Bile Ducts, Intrahepatic/pathology ; Bile Duct Neoplasms/pathology
    Language English
    Publishing date 2023-09-13
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-023-14254-0
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Exceptional Pathologic Response to Preoperative Therapy for Colorectal Liver Metastases.

    Lendoire, Mateo / Maki, Harufumi / Haddad, Antony / Newhook, Timothy E / Tzeng, Ching-Wei D / Vauthey, Jean-Nicolas / Tran Cao, Hop S

    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract

    2024  

    Language English
    Publishing date 2024-05-07
    Publishing country Netherlands
    Document type Journal Article
    ZDB-ID 2012365-6
    ISSN 1873-4626 ; 1934-3213 ; 1091-255X
    ISSN (online) 1873-4626 ; 1934-3213
    ISSN 1091-255X
    DOI 10.1016/j.gassur.2024.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Current Perspectives and Progress in Preoperative Portal Vein Embolization with Stem Cell Augmentation (PVESA).

    Barcena, Allan John R / Owens, Tyler C / Melancon, Sophie / Workeneh, Isias / Tran Cao, Hop S / Vauthey, Jean-Nicolas / Huang, Steven Y

    Stem cell reviews and reports

    2024  

    Abstract: Portal vein embolization with stem cell augmentation (PVESA) is an emerging approach for enhancing the growth of the liver segment that will remain after surgery (i.e., future liver remnant, FLR) in patients with liver cancer. Conventional portal vein ... ...

    Abstract Portal vein embolization with stem cell augmentation (PVESA) is an emerging approach for enhancing the growth of the liver segment that will remain after surgery (i.e., future liver remnant, FLR) in patients with liver cancer. Conventional portal vein embolization (PVE) aims to induce preoperative FLR growth, but it has a risk of failure in patients with underlying liver dysfunction and comorbid illnesses. PVESA combines PVE with stem cell therapy to potentially improve FLR size and function more effectively and efficiently. Various types of stem cells can help improve liver growth by secreting paracrine signals for hepatocyte growth or by transforming into hepatocytes. Mesenchymal stem cells (MSCs), unrestricted somatic stem cells, and small hepatocyte-like progenitor cells have been used to augment liver growth in preclinical animal models, while clinical studies have demonstrated the benefit of CD133 + bone marrow-derived MSCs and hematopoietic stem cells. These investigations have shown that PVESA is generally safe and enhances liver growth after PVE. However, optimizing the selection, collection, and application of stem cells remains crucial to maximize benefits and minimize risks. Additionally, advanced stem cell technologies, such as priming, genetic modification, and extracellular vesicle-based therapy, that could further enhance efficacy outcomes should be evaluated. Despite its potential, PVESA requires more investigations, particularly mechanistic studies that involve orthotopic animal models of liver cancer with concomitant liver injury as well as larger human trials.
    Language English
    Publishing date 2024-04-13
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 2495577-2
    ISSN 2629-3277 ; 1558-6804 ; 1550-8943
    ISSN (online) 2629-3277 ; 1558-6804
    ISSN 1550-8943
    DOI 10.1007/s12015-024-10719-1
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  8. Article ; Online: ASO Author Reflections: Role of Neoadjuvant Therapy in Surgically Resectable Intrahepatic Cholangiocarcinoma.

    Mason, Meredith C / Tran Cao, Hop S

    Annals of surgical oncology

    2021  Volume 28, Issue 11, Page(s) 6736–6737

    MeSH term(s) Bile Duct Neoplasms/surgery ; Bile Ducts, Intrahepatic ; Cholangiocarcinoma/surgery ; Humans ; Neoadjuvant Therapy
    Language English
    Publishing date 2021-01-15
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-09541-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: ASO Author Reflections: Robotic Hepatobiliary Surgery with Fluorescence Guidance-Taking Advantage of the Available Technology.

    Newton, Andrew D / Tran Cao, Hop S

    Annals of surgical oncology

    2021  Volume 28, Issue 11, Page(s) 6835–6836

    MeSH term(s) Fluorescence ; Humans ; Robotic Surgical Procedures ; Technology
    Language English
    Publishing date 2021-03-30
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-021-09926-8
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Repeat hepatectomy for recurrent colorectal cancer liver metastases after two-stage hepatectomy-limitations and opportunities.

    Tran Cao, Hop S / Vauthey, Jean-Nicolas

    Hepatobiliary surgery and nutrition

    2020  Volume 9, Issue 1, Page(s) 65–66

    Language English
    Publishing date 2020-03-05
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn.2019.06.07
    Database MEDical Literature Analysis and Retrieval System OnLINE

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