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  1. Article ; Online: COVID-19

    TRINDADE, GUILHERME G. / CAXITO, SAMYRA M.C. / XAVIER, ALESSANDRA REJANE E.O. / XAVIER, MAURO A.S. / BRANDÃO, FABIANA

    Anais da Academia Brasileira de Ciências v.92 n.2 2020

    therapeutic approaches description and discussion

    2020  

    Abstract: Abstract Abstract: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since ...

    Abstract Abstract Abstract: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the “Spanish flu” pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
    Keywords antivirals ; antiparasitic ; COVID-19 ; SARS-CoV-2 ; therapeutic approaches ; covid19
    Language English
    Publishing date 2020-01-01
    Publisher Academia Brasileira de Ciências
    Publishing country br
    Document type Article ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  2. Article ; Online: COVID-19: therapeutic approaches description and discussion.

    Trindade, Guilherme G / Caxito, Samyra M C / Xavier, Alessandra Rejane E O / Xavier, Mauro A S / BrandÃo, Fabiana

    Anais da Academia Brasileira de Ciencias

    2020  Volume 92, Issue 2, Page(s) e20200466

    Abstract: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" ... ...

    Abstract COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
    MeSH term(s) Anti-Bacterial Agents/administration & dosage ; Anti-Bacterial Agents/chemistry ; Anti-Bacterial Agents/pharmacology ; Antiparasitic Agents/administration & dosage ; Antiparasitic Agents/chemistry ; Antiparasitic Agents/pharmacology ; Antiviral Agents/administration & dosage ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Betacoronavirus/drug effects ; COVID-19 ; Coronavirus Infections/drug therapy ; Humans ; Macrolides/administration & dosage ; Macrolides/chemistry ; Macrolides/pharmacology ; Pandemics ; Pneumonia, Viral/drug therapy ; SARS-CoV-2 ; Serine Proteinase Inhibitors/administration & dosage ; Serine Proteinase Inhibitors/chemistry ; Serine Proteinase Inhibitors/pharmacology
    Chemical Substances Anti-Bacterial Agents ; Antiparasitic Agents ; Antiviral Agents ; Macrolides ; Serine Proteinase Inhibitors
    Keywords covid19
    Language English
    Publishing date 2020-06-15
    Publishing country Brazil
    Document type Journal Article ; Review
    ZDB-ID 2046885-4
    ISSN 1678-2690 ; 0001-3765
    ISSN (online) 1678-2690
    ISSN 0001-3765
    DOI 10.1590/0001-3765202020200466
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: COVID-19: therapeutic approaches description and discussion

    Trindade, Guilherme G / Caxito, Samyra M C / Xavier, Alessandra Rejane E O / Xavier, Mauro A S / BrandÃo, Fabiana

    An Acad Bras Cienc

    Abstract: COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" ... ...

    Abstract COVID-19 emerged in December 2019 in China, and since then, has disrupted global public health and changed economic paradigms. In dealing with the new Coronavirus, SARS-CoV-2, the world has not faced such extreme global fragility since the "Spanish flu" pandemic in 1918. Researchers globally are dedicating efforts to the search for an effective treatment for COVID-19. Drugs already used in a clinical setting for other pathologies have been tested as a new therapeutic approach against SARS-CoV-2, setting off a frenzy over the preliminary data of different studies. This work aims to compile and discuss the data published thus far. Despite the potential effects of some antivirals and antiparasitic against COVID-19, clinical studies must confirm real effectiveness. However, non-pharmacological approaches have proven to be the most efficient strategy to date.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #32556054
    Database COVID19

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