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Article ; Online: Serum creatinine improves body mass index survival prediction in hemodialysis patients: a 1-year prospective cohort analysis from the ARNOS study.

Moreau-Gaudry, Xavier / Guebre-Egziabher, Fitsum / Jean, Guillaume / Genet, Leslie / Lataillade, Dominique / Legrand, Eric / Kuentz, Francois / Trolliet, Pierre / Fouque, Denis

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

2011 Volume 21, Issue 5, Page(s) 369–375

Abstract: Objective: This study sought to better characterize the relationships between body mass index (BMI) and lean body mass (LBM) as assessed by serum creatinine (SCr) and mortality.: Design: The data were collected from a prospective prevalent cohort in ... ...

Abstract	Objective: This study sought to better characterize the relationships between body mass index (BMI) and lean body mass (LBM) as assessed by serum creatinine (SCr) and mortality. Design: The data were collected from a prospective prevalent cohort in maintenance hemodialysis patients. Setting: The study was carried out in 25 dialysis units in Rhônes Alpes area (France and Switzerland). Patient: A total of 1,205 patients were followed up for 1-year, starting July 1, 2005. Outcome: Mortality as well as clinical and biological routine parameters were recorded. Kaplan-Meier, Cox model, Log rank test were used for the statistical analysis. Results: We found that SCr was a strong predictor of mortality (P < .001), whereas BMI was not. Additionally, higher BMI lost its protective effect when it was associated with low SCr. Survival was strongly reduced in patients having a predialysis SCr <717 μmol/L in patients with a BMI >23 (P < .001). Conclusion: BMI should not be used by itself but in conjunction with SCr as a surrogate of LBM to improve its morbid-mortality predictive power. LBM should also be taken into account in further survival studies carried out in hemodialysis patients.
MeSH term(s)	Aged ; Aged, 80 and over ; Body Composition ; Body Mass Index ; Creatinine/blood ; Data Collection ; Female ; France ; Humans ; Kaplan-Meier Estimate ; Kidney Failure, Chronic/physiopathology ; Kidney Failure, Chronic/therapy ; Male ; Middle Aged ; Proportional Hazards Models ; Prospective Studies ; Renal Dialysis/mortality ; Serum Albumin/analysis ; Switzerland
Chemical Substances	Serum Albumin ; Creatinine (AYI8EX34EU)
Language	English
Publishing date	2011-09
Publishing country	United States
Document type	Journal Article
ZDB-ID	1080003-7
ISSN	1532-8503 ; 1051-2276
ISSN (online)	1532-8503
ISSN	1051-2276
DOI	10.1053/j.jrn.2010.08.005
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Article ; Online: Confounding factors for early death in incident end-stage renal disease patients: Role of emergency dialysis start.

Descamps, Chrystèle / Labeeuw, Michel / Trolliet, Pierre / Cahen, Rémi / Ecochard, René / Pouteil-Noble, Claire / Villar, Emmanuel

Hemodialysis international. International Symposium on Home Hemodialysis

2011 Volume 15, Issue 1, Page(s) 23–29

Abstract: Hemodialysis (HD) has been associated with higher 1-year mortality than peritoneal dialysis (PD) after dialysis start. Confounding effects of late referral, emergency dialysis start, or start with central venous catheter on this association have never ... ...

Abstract	Hemodialysis (HD) has been associated with higher 1-year mortality than peritoneal dialysis (PD) after dialysis start. Confounding effects of late referral, emergency dialysis start, or start with central venous catheter on this association have never been studied concomitantly. Survival was studied among the 495 incident dialysed patients in our department from 1995 to 2006 and followed at least 1 year until December 31, 2007. Nested Cox models adjusted on patient characteristics explored factors associated with 1-year and ≥1-year mortality. Hemodialysis patients were 332 (67.1%), 104 (21.0%) were late referred (<6 months), 167 (33.7%) started dialysis in emergency, and 144 (29.1%) started with central venous catheter. When adjusted only on age, sex, and comorbidities, HD was associated with poor 1-year outcome: adjusted hazard ratio (aHR) for death in HD vs. PD was 1.77, P=0.02. In fully adjusted model, among first dialysis feature variables, only emergency dialysis start was significantly associated with 1-year mortality: aHR 1.53, P=0.02. Dialysis modality was not associated with 1-year mortality rates in this fully adjusted model: aHR in HD vs. PD became 1.03, P=0.91. In ≥1-year period, HD was associated with lower mortality than PD (aHR 0.61, P=0.004), whereas other first dialysis features were not associated with death. Other factors associated with death were age, type 2 diabetes, peripheral vascular disease, heart failure, and hepatic failure. Negative association between HD and 1-year survival on dialysis was explained by confounders. Emergency dialysis start was strongly associated with early mortality on dialysis. Its prevention may improve patient survival.
MeSH term(s)	Cohort Studies ; Female ; Humans ; Kidney Failure, Chronic/complications ; Kidney Failure, Chronic/mortality ; Male ; Middle Aged ; Peritoneal Dialysis/methods ; Peritoneal Dialysis/mortality ; Prospective Studies ; Renal Dialysis/methods ; Renal Dialysis/mortality
Language	English
Publishing date	2011-01
Publishing country	Canada
Document type	Journal Article
ZDB-ID	2192458-2
ISSN	1542-4758 ; 1492-7535
ISSN (online)	1542-4758
ISSN	1492-7535
DOI	10.1111/j.1542-4758.2010.00513.x
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Article: Les Huaqiao (Chinois d'outre-mer) et le socialisme du Continent

Trolliet, Pierre

Revue tiers-monde Vol. 22 , p. 459-466

une autre voie?

1981 Volume 22, Page(s) 459–466

Author's details	Pierre Trolliet
Keywords	Volksgruppe chinesische ; Sozialismus ; China
Publisher	Colin
Publishing place	Paris
Document type	Article
ZDB-ID	5242-5
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Book: La Chine et son économie

Trolliet, Pierre

(Collection U)

1981

Author's details	Pierre Trolliet
Series title	Collection U
Keywords	Entwicklung ; Wirtschaftswachstum ; Industrialisierung ; China
Language	French
Size	283 p, ill, 23 cm
Publisher	A. Colin
Publishing place	Paris
Document type	Book
Note	Bibliography: p. 275-[276]
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Article: Poor prognosis of heart transplant patients with end-stage renal failure.

Villar, Emmanuel / Boissonnat, Pascale / Sebbag, Laurent / Hendawy, Achraf / Cahen, Rémi / Trolliet, Pierre / Labeeuw, Michel / Ecochard, René / Pouteil-Noble, Claire

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

2007 Volume 22, Issue 5, Page(s) 1383–1389

Abstract: Background: Chronic kidney disease (CKD) and end-stage renal failure (ESRF) are major complications after a heart transplant. The aim of this study is to compare survival in heart transplant (HT) vs non-heart transplant (non-HT) patients starting ... ...

Abstract	Background: Chronic kidney disease (CKD) and end-stage renal failure (ESRF) are major complications after a heart transplant. The aim of this study is to compare survival in heart transplant (HT) vs non-heart transplant (non-HT) patients starting dialysis. Methods: Survival was studied among the 539 newly dialysed patients between 1 January 1995 and 31 December 2005 in our Department. All patients were prospectively followed from the date of first dialysis up to death or 31 December 2005. Multivariate survival analysis adjusted on baseline characteristics was performed with the Cox model. Results: There were 21 HT patients and they were younger than non-HT patients at first dialysis: 58.6+/-11.6 vs 63.0+/-16.2 years (P=0.09). Calcineurin inhibitor nephrotoxicity was the main cause of ESRF in HT patients (47.6%). Crude 1, 3 and 5-year survival rates in HT and in non-HT patients were as follows: 76.2%, 57.1%, 28.6% and 79.1%, 58.7%, 46.7% (P=0.2). The adjusted hazard ratio of death in HT vs non-HT patients was 2.27 [1.33-3.87], P=0.003. Sudden death was the main cause of death in HT patients, in 33.3% vs 10.4% in non-HT patients (P=0.01). Five HT patients benefited from renal transplant. They were all alive at the end of the study period, while one patient among the 16 remaining on dialysis survived. Conclusion: HT patients with CKD who reached ESRF have a poor outcome after starting dialysis in comparison with other ESRF patients. Improvement in renal function management in the case of CKD is needed in these patients and non-nephrotoxic immunosuppressive regimens have to be evaluated. Renal transplant should be the ESRF treatment of choice in HT patients.
MeSH term(s)	Aged ; Cause of Death ; Female ; Heart Transplantation/adverse effects ; Heart Transplantation/mortality ; Humans ; Kidney Failure, Chronic/etiology ; Kidney Failure, Chronic/surgery ; Kidney Failure, Chronic/therapy ; Kidney Transplantation ; Male ; Middle Aged ; Multivariate Analysis ; Prognosis ; Proportional Hazards Models ; Prospective Studies ; Renal Dialysis ; Risk Factors ; Survival Analysis
Language	English
Publishing date	2007-05
Publishing country	England
Document type	Comparative Study ; Journal Article
ZDB-ID	90594-x
ISSN	1460-2385 ; 0931-0509
ISSN (online)	1460-2385
ISSN	0931-0509
DOI	10.1093/ndt/gfl811
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Zs.A 2198: Show issues			Location: Je nach Verfügbarkeit (siehe Angabe bei Bestand) bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular Jg. 1995 - 2021: Lesesall (1.OG) ab Jg. 2022: Lesesaal (EG)
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Book: L'économie de Singapour

Trolliet, Pierre / Mitry, Nicole de

(Notes et études documentaires ; nos 4543-4544)

1979

Author's details	Pierre Trolliet, Nicole de Mitry
Series title	Notes et études documentaires ; nos 4543-4544
Keywords	Entwicklung ; Singapur
Language	French
Size	96 p, ill, 24 cm
Publisher	Documentation française
Publishing place	Paris
Document type	Book
Note	Bibliography: p. 93 ; ISSN 0029-4004
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Article: Les communes populaires rurales chinoises

Trolliet, Pierre

Revue tiers-monde Vol. 3, No. 9/10 , p. 229-269

1962 Volume 3, Issue 9, Page(s) 229–269

Author's details	Pierre Trolliet
Keywords	Agrarsozialismus ; China
Publisher	Colin
Publishing place	Paris
Document type	Article
ZDB-ID	5242-5
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Article ; Online: Observational Study of a French and Belgian Multicenter Cohort of 23 Patients Diagnosed in Adulthood With Mevalonate Kinase Deficiency.

Durel, Cécile-Audrey / Aouba, Achille / Bienvenu, Boris / Deshayes, Samuel / Coppéré, Brigitte / Gombert, Bruno / Acquaviva-Bourdain, Cécile / Hachulla, Eric / Lecomte, Frédéric / Touitou, Isabelle / Ninet, Jacques / Philit, Jean-Baptiste / Messer, Laurent / Brouillard, Marc / Girard-Madoux, Marie-Hélène / Moutschen, Michel / Raison-Peyron, Nadia / Hutin, Pascal / Duffau, Pierre /

Trolliet, Pierre / Hatron, Pierre-Yves / Heudier, Philippe / Cevallos, Ramiro / Lequerré, Thierry / Brousse, Valentine / Lesire, Vincent / Audia, Sylvain / Maucort-Boulch, Delphine / Cuisset, Laurence / Hot, Arnaud

Medicine

2016 Volume 95, Issue 11, Page(s) e3027

Abstract: The aim of this study was to describe the clinical and biological features of Mevalonate kinase deficiency (MKD) in patients diagnosed in adulthood. This is a French and Belgian observational retrospective study from 2000 to 2014. To constitute the ... ...

Abstract	The aim of this study was to describe the clinical and biological features of Mevalonate kinase deficiency (MKD) in patients diagnosed in adulthood. This is a French and Belgian observational retrospective study from 2000 to 2014. To constitute the cohort, we cross-check the genetic and biochemical databases. The clinical, enzymatic, and genetic data were gathered from medical records. Twenty-three patients were analyzed. The mean age at diagnosis was 40 years, with a mean age at onset of symptoms of 3 years. All symptomatic patients had fever. Febrile attacks were mostly associated with arthralgia (90.9%); lymphadenopathy, abdominal pain, and skin lesions (86.4%); pharyngitis (63.6%); cough (59.1%); diarrhea, and hepatosplenomegaly (50.0%). Seven patients had psychiatric symptoms (31.8%). One patient developed recurrent seizures. Three patients experienced renal involvement (13.6%). Two patients had angiomyolipoma (9.1%). All but one tested patients had elevated serum immunoglobulin (Ig) D level. Twenty-one patients had genetic diagnosis; most of them were compound heterozygote (76.2%). p.Val377Ile was the most prevalent mutation. Structural articular damages and systemic AA amyloidosis were the 2 most serious complications. More than 65% of patients displayed decrease in severity and frequency of attacks with increasing age, but only 35% achieved remission. MKD diagnosed in adulthood shared clinical and genetic features with classical pediatric disease. An elevated IgD concentration is a good marker for MKD in adults. Despite a decrease of severity and frequency of attacks with age, only one-third of patients achieved spontaneous remission.
MeSH term(s)	Adolescent ; Adult ; Aged ; Belgium/epidemiology ; Female ; France/epidemiology ; Humans ; Male ; Mevalonate Kinase Deficiency/complications ; Mevalonate Kinase Deficiency/drug therapy ; Mevalonate Kinase Deficiency/epidemiology ; Middle Aged ; Retrospective Studies ; Young Adult
Language	English
Publishing date	2016-03
Publishing country	United States
Document type	Journal Article ; Multicenter Study ; Observational Study
ZDB-ID	80184-7
ISSN	1536-5964 ; 0025-7974
ISSN (online)	1536-5964
ISSN	0025-7974
DOI	10.1097/MD.0000000000003027
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Article ; Online: Rituximab in severe lupus nephritis: early B-cell depletion affects long-term renal outcome.

Melander, Catherine / Sallée, Marion / Trolliet, Pierre / Candon, Sophie / Belenfant, Xavier / Daugas, Eric / Rémy, Phillipe / Zarrouk, Virginie / Pillebout, Evangéline / Jacquot, Christian / Boffa, Jean-Jacques / Karras, Alexandre / Masse, Virginie / Lesavre, Philippe / Elie, Caroline / Brocheriou, Isabelle / Knebelmann, Bertrand / Noël, Laure-Hélène / Fakhouri, Fadi

Clinical journal of the American Society of Nephrology : CJASN

2009 Volume 4, Issue 3, Page(s) 579–587

Abstract: Background and objectives: Standard treatment for lupus nephritis, including corticosteroids and cyclophosphamide, is efficient but is still associated with refractory or relapsing disease, or severe deleterious effects. Rituximab, a monoclonal chimeric ...

Abstract	Background and objectives: Standard treatment for lupus nephritis, including corticosteroids and cyclophosphamide, is efficient but is still associated with refractory or relapsing disease, or severe deleterious effects. Rituximab, a monoclonal chimeric anti-B cell antibody, is increasingly used in patients with lupus nephritis, but reported series were small and had a short follow-up. Design, setting, participants, & measurements: The authors analyzed clinical and histologic data of 20 patients who were treated with rituximab for lupus nephritis and followed up for at least 12 mo. Results: Nineteen women and one man received rituximab as induction treatment for an active class IV (15 cases) or class V (5 cases) lupus nephritis. Rituximab was given for lupus nephritis refractory to standard treatment (12 cases), for relapsing disease (6 cases), or as first-line treatment (2 cases). Three patients received cyclophosphamide concomitantly with rituximab. Ten received new injections of rituximab as maintenance therapy. Side effects included mainly five infections and four moderate neutropenias. After a median follow-up of 22 mo, complete or partial renal remission was obtained in 12 patients (60%). Lupus nephritis relapsed in one patient, who responded to a new course of rituximab. The achievement of B cell depletion 1 mo after rituximab, which negatively correlated with black ethnicity and hypoalbuminemia, was strongly associated with renal response. Rapidly progressive glomerulonephritis did not respond to rituximab. Conclusion: Rituximab is an interesting therapeutic option in relapsing or refractory lupus nephritis when early B cell depletion is obtained.
MeSH term(s)	African Continental Ancestry Group ; Antibodies, Monoclonal/adverse effects ; Antibodies, Monoclonal/therapeutic use ; Antibodies, Monoclonal, Murine-Derived ; B-Lymphocytes/drug effects ; B-Lymphocytes/immunology ; Cyclophosphamide/therapeutic use ; Disease Progression ; Drug Therapy, Combination ; Female ; France ; Glomerulonephritis, Membranous/drug therapy ; Glomerulonephritis, Membranous/ethnology ; Glomerulonephritis, Membranous/immunology ; Glomerulonephritis, Membranous/physiopathology ; Humans ; Hypoalbuminemia/drug therapy ; Hypoalbuminemia/immunology ; Immunologic Factors/adverse effects ; Immunologic Factors/therapeutic use ; Immunosuppressive Agents/therapeutic use ; Kidney/drug effects ; Kidney/physiopathology ; Kidney Function Tests ; Lupus Nephritis/drug therapy ; Lupus Nephritis/ethnology ; Lupus Nephritis/immunology ; Lupus Nephritis/physiopathology ; Lymphocyte Depletion/methods ; Male ; Patient Selection ; Recurrence ; Retrospective Studies ; Rituximab ; Severity of Illness Index ; Time Factors ; Treatment Outcome
Chemical Substances	Antibodies, Monoclonal ; Antibodies, Monoclonal, Murine-Derived ; Immunologic Factors ; Immunosuppressive Agents ; Rituximab (4F4X42SYQ6) ; Cyclophosphamide (8N3DW7272P)
Language	English
Publishing date	2009-03-04
Publishing country	United States
Document type	Journal Article ; Multicenter Study
ZDB-ID	2226665-3
ISSN	1555-905X ; 1555-9041
ISSN (online)	1555-905X
ISSN	1555-9041
DOI	10.2215/CJN.04030808
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Article ; Online: Interleukin 17 acts in synergy with B cell-activating factor to influence B cell biology and the pathophysiology of systemic lupus erythematosus.

Doreau, Agnès / Belot, Alexandre / Bastid, Jérémy / Riche, Benjamin / Trescol-Biemont, Marie-Claude / Ranchin, Bruno / Fabien, Nicole / Cochat, Pierre / Pouteil-Noble, Claire / Trolliet, Pierre / Durieu, Isabelle / Tebib, Jacques / Kassai, Berhouz / Ansieau, Stéphane / Puisieux, Alain / Eliaou, Jean-François / Bonnefoy-Bérard, Nathalie

publication RETRACTED

Nature immunology

2009 Volume 10, Issue 7, Page(s) 778–785

Abstract: Studies have suggested involvement of interleukin 17 (IL-17) in autoimmune diseases, although its effect on B cell biology has not been clearly established. Here we demonstrate that IL-17 alone or in combination with B cell-activating factor controlled ... ...

Abstract	Studies have suggested involvement of interleukin 17 (IL-17) in autoimmune diseases, although its effect on B cell biology has not been clearly established. Here we demonstrate that IL-17 alone or in combination with B cell-activating factor controlled the survival and proliferation of human B cells and their differentiation into immunoglobulin-secreting cells. This effect was mediated mainly through the nuclear factor-kappaB-regulated transcription factor Twist-1. In support of the relevance of our observations and the potential involvement of IL-17 in B cell biology, we found that the serum of patients with systemic lupus erythematosus had higher concentrations of IL-17 than did the serum of healthy people and that IL-17 abundance correlated with the disease severity of systemic lupus erythematosus.
MeSH term(s)	Antigens, CD19/metabolism ; Apoptosis/drug effects ; B-Cell Activating Factor/pharmacology ; B-Lymphocytes/cytology ; B-Lymphocytes/drug effects ; B-Lymphocytes/metabolism ; Cell Differentiation/drug effects ; Cell Line, Tumor ; Cell Proliferation/drug effects ; Cell Survival/drug effects ; Cells, Cultured ; Dose-Response Relationship, Drug ; Drug Synergism ; Female ; Humans ; Immunoblotting ; Immunoglobulins/metabolism ; Interleukin-17/blood ; Interleukin-17/genetics ; Interleukin-17/pharmacology ; Lupus Erythematosus, Systemic/blood ; Lupus Erythematosus, Systemic/pathology ; Male ; Minor Histocompatibility Antigens ; NF-kappa B/metabolism ; Nuclear Proteins/genetics ; Nuclear Proteins/metabolism ; Proto-Oncogene Proteins c-bcl-2/genetics ; Proto-Oncogene Proteins c-bcl-2/metabolism ; Repressor Proteins/genetics ; Repressor Proteins/metabolism ; Reverse Transcriptase Polymerase Chain Reaction ; Time Factors ; Twist-Related Protein 1/genetics ; Twist-Related Protein 1/metabolism
Chemical Substances	Antigens, CD19 ; B-Cell Activating Factor ; BCL2-related protein A1 ; Immunoglobulins ; Interleukin-17 ; Minor Histocompatibility Antigens ; NF-kappa B ; Nuclear Proteins ; Proto-Oncogene Proteins c-bcl-2 ; Repressor Proteins ; TWIST1 protein, human ; TWIST2 protein, human ; Twist-Related Protein 1
Language	English
Publishing date	2009-05-31
Publishing country	United States
Document type	Journal Article ; Research Support, Non-U.S. Gov't ; Retracted Publication
ZDB-ID	2016987-5
ISSN	1529-2916 ; 1529-2908
ISSN (online)	1529-2916
ISSN	1529-2908
DOI	10.1038/ni.1741
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