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Article ; Online: Adaption of tele-behavioral activation to increase physical activity in depression: Protocol for iterative development and evaluation.

Rethorst, Chad D / Trombello, Joseph M / Chen, Patricia / Carmody, Thomas J / Lazalde, Alejandra / Trivedi, Madhukar H

Contemporary clinical trials communications

2023 Volume 33, Page(s) 101103

Abstract: Background: Poor treatment outcomes, disease recurrence, and medical co-morbidities contribute to the significant burden caused by depressive disorders. Increasing physical activity in persons with depression has the potential to improve both depression ...

Abstract	Background: Poor treatment outcomes, disease recurrence, and medical co-morbidities contribute to the significant burden caused by depressive disorders. Increasing physical activity in persons with depression has the potential to improve both depression treatment outcomes and physical health. However, evidence for physical activity interventions that can be delivered as part of depression treatment remains limited. This study will examine a Behavioral Activation teletherapy intervention adapted to include a specific focus on increasing physical activity. Methods: The two-phase study will include a preliminary pilot study (n = 15) to evaluate and refine the manualized intervention using a mixed-methods approach followed by a single-arm study to evaluate feasibility and preliminary efficacy of the adapted BA teletherapy. Participants will be adults, age 18-64, with moderate to severe depressive symptoms (defined as a PHQ-9 score ≥10) and who currently engage in 90 min or less of moderate-to-vigorous physical activity. Individuals will be excluded if they have a current or past manic or hypomanic episode, psychosis, schizophrenia or schizophreniform disorder, or active suicidal ideation, or if not medically-cleared to exercise. The BA intervention will consist of 8 weekly sessions, followed by 2 bi-weekly booster sessions. Feasibility outcomes will include metrics of screening, enrollment, intervention adherence and fidelity, and participant retention. Intervention preliminary efficacy will be evaluated through assessment of changes in depressive symptoms and moderate-to-vigorous physical activity. Conclusion: Data from this trial will be used to support the conduct of a randomized controlled trial to evaluate the efficacy of the adapted BA intervention.
Language	English
Publishing date	2023-04-15
Publishing country	Netherlands
Document type	Journal Article
ISSN	2451-8654
ISSN (online)	2451-8654
DOI	10.1016/j.conctc.2023.101103
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Article ; Online: Burnout During the COVID-19 Pandemic: Descriptive and Predictive Data from a Survey of Psychologists at a Single Academic Medical Center.

Trombello, Joseph M / David, Natalia S / Robbins, Mona A / Ruchinskas, Robert A

Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry

2021 Volume 46, Issue 6, Page(s) 718–722

Abstract: Objective: Burnout in academic medicine has been widely studied, but most work has been conducted among physicians. Psychologists in academic medicine have unique burnout factors. Therefore, investigating the prevalence and predictors of burnout among ... ...

Abstract	Objective: Burnout in academic medicine has been widely studied, but most work has been conducted among physicians. Psychologists in academic medicine have unique burnout factors. Therefore, investigating the prevalence and predictors of burnout among psychologists in academic medicine during the COVID-19 pandemic represents an important addition to the literature. Methods: Sixty-two psychologists responded to burnout-related items in a larger, 40-item Psychiatry Department climate survey conducted from October to November 2020. Five items from the MINI-Z survey were administered to examine control over workload and sufficiency of documentation time as predictors of both continuous and dichotomously defined burnout. Linear and logistic regression was employed with years as a faculty member entered as a covariate. Results: Slightly less than half (48.4%) of respondents met dichotomous criteria for burnout. Faculty with fewer years of experience scored higher on their level of continuous burnout. Both control over workload and sufficiency of time for documentation were independent predictors of continuous burnout, but only control over workload remained a statistically significant predictor in a simultaneous model. Control over workload was a significant predictor in dichotomous models but did not remain so once sufficiency of documentation time was also added. Conclusion: Burnout prevalence among psychologists was comparable to rates among physicians at other institutions, even when examined during the COVID-19 pandemic. Academic medicine administrators and organizational leaders should consider policies and programming to increase control over workload, especially among junior psychologist faculty.
MeSH term(s)	Humans ; Job Satisfaction ; COVID-19/epidemiology ; Pandemics ; Burnout, Professional/epidemiology ; Burnout, Professional/psychology ; Surveys and Questionnaires ; Workload/psychology ; Academic Medical Centers
Language	English
Publishing date	2021-11-29
Publishing country	United States
Document type	Journal Article
ZDB-ID	1045331-3
ISSN	1545-7230 ; 1042-9670
ISSN (online)	1545-7230
ISSN	1042-9670
DOI	10.1007/s40596-021-01562-4
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Article ; Online: Suicide risk assessment and suicide risk management protocol for the Texas Youth Depression and Suicide Research Network.

Hughes, Jennifer L / Trombello, Joseph M / Kennard, Betsy D / Slater, Holli / Rezaeizadeh, Afsaneh / Claassen, Cynthia / Wakefield, Sarah M / Trivedi, Madhukar H

Contemporary clinical trials communications

2023 Volume 33, Page(s) 101151

Abstract: Introduction: Suicide prevention research is a national priority, and national guidance includes the development of suicide risk management protocols (SRMPs) for the assessment and management of suicidal ideation and behavior in research trials. Few ... ...

Abstract	Introduction: Suicide prevention research is a national priority, and national guidance includes the development of suicide risk management protocols (SRMPs) for the assessment and management of suicidal ideation and behavior in research trials. Few published studies describe how researchers develop and implement SRMPs or articulate what constitutes an acceptable and effective SRMP. Methods: The Texas Youth Depression and Suicide Research Network (TX-YDSRN) was developed with the goal of evaluating screening and measurement-based care in Texas youth with depression or suicidality (i.e., suicidal ideation and/or suicidal behavior). The SRMP was developed for TX-YDSRN through a collaborative, iterative process, consistent with a Learning Healthcare System model. Results: The final SMRP included training, educational resources for research staff, educational resources for research participants, risk assessment and management strategies, and clinical and research oversight. Conclusion: The TX-YDSRN SRMP is one methodology for addressing youth participant suicide risk. The development and testing of standard methodologies with a focus on participant safety is an important next step to further the field of suicide prevention research.
Language	English
Publishing date	2023-05-25
Publishing country	Netherlands
Document type	Journal Article
ISSN	2451-8654
ISSN (online)	2451-8654
DOI	10.1016/j.conctc.2023.101151
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Article ; Online: Psychometric properties of the Treatment Effectiveness Assessment in methamphetamine use disorder.

Vo, Hoa T / Kulikova, Alexandra / Mayes, Taryn L / Carmody, Thomas / Shoptaw, Steve / Ling, Walter / Trombello, Joseph M / Trivedi, Madhukar H

Journal of substance use and addiction treatment

2023 Volume 151, Page(s) 209085

Abstract: Introduction: The ability for people living with stimulant use disorder to live meaningful lives requires not only abstinence from addictive substances, but also healthy engagement with their community, lifestyle practices, and overall health. The ... ...

Abstract	Introduction: The ability for people living with stimulant use disorder to live meaningful lives requires not only abstinence from addictive substances, but also healthy engagement with their community, lifestyle practices, and overall health. The Treatment Effectiveness Assessment (TEA) assesses components of recovery consisting of four functional domains: substance use, health, lifestyle, and community. This secondary data analysis of 403 participants with severe methamphetamine use disorder tested the reliability and validity of the TEA. Methods: Participants were enrolled in the Accelerated Development of Additive Pharmacotherapy Treatment (ADAPT-2) for methamphetamine use disorder. The study used total TEA and domain scores at baseline to assess factor structure and internal consistency, as well as construct validity related to substance cravings (visual analog scale [VAS]), quality of life (quality-of-life assessment [QoL]), mental health (Patient Health Questionnaire-9 [PHQ-9], Concise Health Risk Tracking Scale Self-Report [CHRT-SR Results: Individual TEA items showed moderate to large correlations with each other (r = 0.27-0.51; p < .001), and strong correlations to the total score (r = 0.69-0.78; p < .001). Internal consistency was strong (coefficient α = 0.73 [0.68-0.77]; coefficient ω = 0.73 [0.69-0.78]). Construct validity was acceptable, with the strongest correlation between the TEA Health item and the general health status item on the QoL (r = 0.53, p < .001). Conclusions: TEA has acceptable levels of reliability and validity supporting prior similar findings in a sample of participants with moderate to severe methamphetamine use disorder. Results from this study provide support for its use in assessing clinically meaningful changes beyond simply reduced substance use.
MeSH term(s)	Humans ; Quality of Life ; Methamphetamine/adverse effects ; Psychometrics ; Reproducibility of Results ; Substance-Related Disorders ; Treatment Outcome
Chemical Substances	Methamphetamine (44RAL3456C)
Language	English
Publishing date	2023-05-26
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ISSN	2949-8759
ISSN (online)	2949-8759
DOI	10.1016/j.josat.2023.209085
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Article ; Online: Corrigendum to 'Two Trajectories of Depressive Symptom Reduction Throughout Behavioral Activation Teletherapy Among Underserved, Ethnically Diverse, Primary Care Patients: A VitalSign

Trombello, Joseph M / South, Charles / Sánchez, Alma / Kahalnik, Farra / Kennard, Beth D / Trivedi, Madhukar H

Behavior therapy

2021 Volume 52, Issue 6, Page(s) 1558

Language	English
Publishing date	2021-09-03
Publishing country	England
Document type	Published Erratum
ZDB-ID	211996-1
ISSN	1878-1888 ; 0005-7894
ISSN (online)	1878-1888
ISSN	0005-7894
DOI	10.1016/j.beth.2021.06.002
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Article ; Online: Diagnosis and Management of Depression in Patients With Kidney Disease.

Gregg, L Parker / Trombello, Joseph M / McAdams, Meredith / Hedayati, S Susan

Seminars in nephrology

2021 Volume 41, Issue 6, Page(s) 505–515

Abstract: Depression disproportionately affects patients with kidney disease, including those with nondialysis chronic kidney disease, end-stage kidney disease requiring dialysis, and kidney transplant recipients. Patients across the spectrum of kidney disease ... ...

Abstract	Depression disproportionately affects patients with kidney disease, including those with nondialysis chronic kidney disease, end-stage kidney disease requiring dialysis, and kidney transplant recipients. Patients across the spectrum of kidney disease should be screened for depression every 6 to 12 months using self-report questionnaires, followed by an interview with a clinician to confirm the presence of sadness or anhedonia when depressive symptoms are identified. Pharmacologic treatment with selective serotonin reuptake inhibitors has not consistently shown benefit compared with placebo and may be associated with serious adverse outcomes including cardiovascular events, bleeding, and fractures. However, based on the availability of alternative therapies, a watchful trial with close monitoring for therapeutic and adverse effects is reasonable. Several clinical trials have suggested that cognitive behavioral therapy and physical activity improve depressive symptoms when compared with a control group. Given the low risk associated with these therapies, they should be recommended to patients who have access and are amenable to such interventions. Future trials are needed to study therapeutic options for depression in nondialysis chronic kidney disease, peritoneal dialysis, or kidney transplant recipients, as well as alternative pharmacologic therapy and combination therapies. Given improvement in depressive symptoms with placebo in existing trials, inclusion of a control group is paramount.
MeSH term(s)	Cognitive Behavioral Therapy ; Depression/complications ; Depression/diagnosis ; Depression/therapy ; Female ; Humans ; Male ; Renal Insufficiency, Chronic/complications ; Renal Insufficiency, Chronic/therapy
Language	English
Publishing date	2021-12-29
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural ; Research Support, Non-U.S. Gov't ; Research Support, U.S. Gov't, Non-P.H.S.
ZDB-ID	604652-6
ISSN	1558-4488 ; 0270-9295
ISSN (online)	1558-4488
ISSN	0270-9295
DOI	10.1016/j.semnephrol.2021.10.003
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Article ; Online: Depressive Symptoms, Criticism, and Counter-Criticism in Marital Interactions.

Trombello, Joseph M / Post, Kristina M / Smith, David A

Family process

2018 Volume 58, Issue 1, Page(s) 165–178

Abstract: Although people with depressive symptoms face criticism, hostility, and rejection in their close relationships, we do not know how they respond. Following interpersonal theories of depression, it might be expected that depressive symptoms would be ... ...

Abstract	Although people with depressive symptoms face criticism, hostility, and rejection in their close relationships, we do not know how they respond. Following interpersonal theories of depression, it might be expected that depressive symptoms would be associated with a tendency to receive and also to express criticism toward one's spouse, and that at least some of this criticism would be a contingent response to criticism received (i.e., "counter-criticism"). However, other research has determined that depressive symptoms/behaviors suppress partner criticism, suggesting that depressed people might respond to partner criticism similarly, by subsequently expressing less criticism. In a sample of 112 married couples, partial correlations, regressions, and Actor-Partner Interdependence Modeling indicated that lower criticism and counter-criticism expression during a laboratory marital interaction task was associated with higher depressive symptoms, especially when such individuals were clinically depressed. Furthermore, during a separate and private Five-Minute Speech Sample, lower criticism by partners was associated with higher depressive symptoms, especially when those who chose the interaction topic were also clinically depressed. All analyses controlled for relationship adjustment. These results suggest that spouses with higher depressive symptoms and clinical depression diagnoses may be suppressing otherwise ordinary criticism expression toward their nondepressed partners; furthermore, nondepressed partners of depressed people are especially likely to display less criticism toward their spouse in a private task.
MeSH term(s)	Adult ; Depression/psychology ; Female ; Hostility ; Humans ; Interpersonal Relations ; Male ; Middle Aged ; Spouses/psychology
Language	English
Publishing date	2018-02-23
Publishing country	United States
Document type	Journal Article ; Research Support, N.I.H., Extramural
ZDB-ID	212740-4
ISSN	1545-5300 ; 0014-7370
ISSN (online)	1545-5300
ISSN	0014-7370
DOI	10.1111/famp.12349
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Article ; Online: Two Trajectories of Depressive Symptom Reduction Throughout Behavioral Activation Teletherapy Among Underserved, Ethnically Diverse, Primary Care Patients: A VitalSign

Trombello, Joseph M / South, Charles / Sánchez, Alma / Kahalnik, Farra / Kennard, Beth D / Trivedi, Madhukar H

Behavior therapy

2020 Volume 51, Issue 6, Page(s) 958–971

Abstract: While prior research has investigated trajectories of depressive symptom change throughout psychotherapy, such work has not been conducted exclusively among underserved patients receiving brief Behavioral Activation (BA) teletherapy, intervention ... ...

Abstract	While prior research has investigated trajectories of depressive symptom change throughout psychotherapy, such work has not been conducted exclusively among underserved patients receiving brief Behavioral Activation (BA) teletherapy, intervention modifications that should reduce barriers to therapy initiation and engagement. The current project used cluster analysis to determine discrete groups of symptom change among patients receiving an 8-session BA teletherapy intervention, and analyzed whether demographic and clinical characteristics were associated with group membership. Data from 105 patients referred from charity primary care clinics and receiving at least two therapy sessions were analyzed. Patients were predominantly female and Latina. The 9-item Patient Health Questionnaire (PHQ-9) was the outcome. Two categories were determined: a larger group (N = 61) demonstrating initially less severe symptoms and experiencing a gradual recovery, and a smaller group beginning with more severe symptoms, and experiencing a steeper recovery. In both groups, a majority of participants experienced at least a 5-point drop in depressive symptoms, while in the latter group, a majority of patients achieved depressive symptom remission (PHQ-9 < 5). Monolingual Spanish speakers were more likely to be in the former group, but no other demographic or clinical characteristics were associated with group membership. In both groups, a majority of the symptom reduction occurred by sessions 4-6. Therefore, two categories of depressive symptom change, slow responders and rapid responders, occur among patients receiving a brief BA teletherapy intervention. No demographic differences aside from primary language, nor any clinical characteristics, distinguish group membership, suggesting similar patterns of symptom reduction among a primarily underserved sample.
MeSH term(s)	Female ; Humans ; Male ; Behavior Therapy ; Depression/therapy ; Primary Health Care ; Psychotherapy ; Telemedicine ; Treatment Outcome
Language	English
Publishing date	2020-01-11
Publishing country	England
Document type	Journal Article ; Research Support, Non-U.S. Gov't
ZDB-ID	211996-1
ISSN	1878-1888 ; 0005-7894
ISSN (online)	1878-1888
ISSN	0005-7894
DOI	10.1016/j.beth.2020.01.002
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Article: PERSONAL VULNERABILITIES AND ASSORTATIVE MATE SELECTION AMONG NEWLYWED SPOUSES.

Trombello, Joseph M / Schoebi, Dominik / Bradbury, Thomas N

Journal of social and clinical psychology

2017 Volume 34, Issue 6, Page(s) 529–553

Abstract: Assortative-mating theories propose that individuals select romantic relationship partners who are similar to them on positive and negative qualities. Furthermore, stress-generation and intergenerational transmission of divorce models argue that one's ... ...

Abstract	Assortative-mating theories propose that individuals select romantic relationship partners who are similar to them on positive and negative qualities. Furthermore, stress-generation and intergenerational transmission of divorce models argue that one's depression history or family-of-origin relationship problems predict qualities of a marital partner that predispose them to relationship distress. We analyzed data from 172 newlywed couples to examine predictors and mediators of a marital partner's risk index. First, an index of one's own and one's partner risk was created through factor analysis and was comprised of measures that indicate insecurity about oneself. This index was significantly correlated with baseline marital satisfaction and, among men, steps toward divorce at follow-up. Then, structural equation modeling tested direct and indirect pathways predicting partner's risk index, analyzing prior depression history and family-of-origin relational impairment as predictors and one's own risk index as the mediator. Results demonstrated that own risk index reliably predicted partner's risk, while own risk index also mediated the relationship between own family-of-origin relational dysfunction/depression history and partner's risk index. These results support assortative mating theories and suggest that the association between adverse family-of-origin relationships or depression history and the risk profile in one's marital partner is explained by one's own risk profile.
Language	English
Publishing date	2017-07-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	226817-6
ISSN	0736-7236
ISSN	0736-7236
DOI	10.1521/jscp.2015.34.6.529
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Article: Psychometrics of the Concise Health Risk Tracking Self-Report (CHRT-SR

Trombello, Joseph M / Kulikova, Alexandra / Mayes, Taryn L / Nandy, Karabi / Carmody, Thomas / Bart, Gavin / Nunes, Edward V / Schmitz, Joy / Kalmin, Mariah / Shoptaw, Steven / Trivedi, Madhukar H

Neuropsychiatric disease and treatment

2023 Volume 19, Page(s) 1443–1454

Abstract: Background: The co-occurrence of suicidality and substance use disorders has been well established, but rating scales to examine suicidal behavior and risk are sparse among participants with substance use disorders. We examined the psychometric ... ...

Abstract	Background: The co-occurrence of suicidality and substance use disorders has been well established, but rating scales to examine suicidal behavior and risk are sparse among participants with substance use disorders. We examined the psychometric properties of the 16-item Concise Health Risk Tracking Scale - Self Report (CHRT-SR Methods: Participants (n = 403) with moderate-to-severe methamphetamine use disorder completed the CHRT-SR Results: CFA revealed a seven-factor model of Pessimism, Helplessness, Social Support, Despair, Impulsivity, Irritability, and Suicidal Thoughts as the best-fitting model. The CHRT-SR Conclusion: The CHRT-SR Clinicaltrialsgov identifier: NCT03078075.
Language	English
Publishing date	2023-06-22
Publishing country	New Zealand
Document type	Journal Article
ZDB-ID	2186503-6
ISSN	1178-2021 ; 1176-6328
ISSN (online)	1178-2021
ISSN	1176-6328
DOI	10.2147/NDT.S406909
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