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  1. Article: Informing patients about blood transfusion.

    Troy-Barnes, Ethan / Feane, Kelly / Carr, Sarah / Uprichard, James

    British journal of hospital medicine (London, England : 2005)

    2017  Volume 78, Issue 11, Page(s) 656

    MeSH term(s) Adult ; Attitude of Health Personnel ; Blood Transfusion/ethics ; Humans ; Transfusion Reaction/prevention & control ; Truth Disclosure/ethics
    Language English
    Publishing date 2017-09-26
    Publishing country England
    Document type Letter
    ISSN 1750-8460
    ISSN 1750-8460
    DOI 10.12968/hmed.2017.78.11.656
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Successful remission induction therapy with gilteritinib in a patient with de novo FLT3-mutated acute myeloid leukaemia and severe COVID-19.

    Wilson, Andrew J / Troy-Barnes, Ethan / Subhan, Maryam / Clark, Fiona / Gupta, Rajeev / Fielding, Adele K / Kottaridis, Panagiotis / Mansour, Marc R / O'Nions, Jenny / Payne, Elspeth / Chavda, Naina / Baker, Robert / Thomson, Kirsty / Khwaja, Asim

    British journal of haematology

    2020  Volume 190, Issue 4, Page(s) e189–e191

    MeSH term(s) Adult ; Aniline Compounds/administration & dosage ; COVID-19/diagnostic imaging ; COVID-19/enzymology ; COVID-19/genetics ; Humans ; Leukemia, Myeloid, Acute/diagnostic imaging ; Leukemia, Myeloid, Acute/drug therapy ; Leukemia, Myeloid, Acute/enzymology ; Leukemia, Myeloid, Acute/genetics ; Male ; Pyrazines/administration & dosage ; Remission Induction ; SARS-CoV-2 ; fms-Like Tyrosine Kinase 3/genetics ; fms-Like Tyrosine Kinase 3/metabolism ; COVID-19 Drug Treatment
    Chemical Substances Aniline Compounds ; Pyrazines ; gilteritinib ; FLT3 protein, human (EC 2.7.10.1) ; fms-Like Tyrosine Kinase 3 (EC 2.7.10.1)
    Keywords covid19
    Language English
    Publishing date 2020-07-19
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.16962
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Plasmacytoma-Like Posttransplant Lymphoproliferative Disease in a Disused Arteriovenous Fistula: The Importance of Histopathology.

    Kousios, Andreas / Storey, Rowland / Troy-Barnes, Ethan / Hamady, Mohamad / Salisbury, Emma / Duncan, Neill / Charif, Rawya / Tam, Frederick W K / Cook, H Terence / Crane, Jeremy / Chaidos, Aristeidis / Roufosse, Candice / Flora, Rashpal

    Kidney international reports

    2019  Volume 4, Issue 5, Page(s) 749–755

    Language English
    Publishing date 2019-02-13
    Publishing country United States
    Document type Case Reports
    ISSN 2468-0249
    ISSN (online) 2468-0249
    DOI 10.1016/j.ekir.2019.02.003
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Successful remission induction therapy with gilteritinib in a patient with de novo FLT3 ‐mutated acute myeloid leukaemia and severe COVID‐19

    Wilson, Andrew J. / Troy‐Barnes, Ethan / Subhan, Maryam / Clark, Fiona / Gupta, Rajeev / Fielding, Adele K. / Kottaridis, Panagiotis / Mansour, Marc R. / O'Nions, Jenny / Payne, Elspeth / Chavda, Naina / Baker, Robert / Thomson, Kirsty / Khwaja, Asim

    British Journal of Haematology

    2020  Volume 190, Issue 4

    Keywords Hematology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.16962
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  5. Article ; Online: Clinical outcomes and risk factors for severe COVID-19 in patients with haematological disorders receiving chemo- or immunotherapy.

    Fox, Thomas A / Troy-Barnes, Ethan / Kirkwood, Amy A / Chan, Wei Yee / Day, James W / Chavda, Selina J / Kumar, Emil A / David, Kate / Tomkins, Oliver / Sanchez, Emilie / Scully, Marie / Khwaja, Asim / Lambert, Jonathan / Singer, Mervyn / Roddie, Claire / Morris, Emma C / Yong, Kwee L / Thomson, Kirsty J / Ardeshna, Kirit M

    British journal of haematology

    2020  Volume 191, Issue 2, Page(s) 194–206

    Abstract: Haematology patients receiving chemo- or immunotherapy are considered to be at greater risk of COVID-19-related morbidity and mortality. We aimed to identify risk factors for COVID-19 severity and assess outcomes in patients where COVID-19 complicated ... ...

    Abstract Haematology patients receiving chemo- or immunotherapy are considered to be at greater risk of COVID-19-related morbidity and mortality. We aimed to identify risk factors for COVID-19 severity and assess outcomes in patients where COVID-19 complicated the treatment of their haematological disorder. A retrospective cohort study was conducted in 55 patients with haematological disorders and COVID-19, including 52 with malignancy, two with bone marrow failure and one immune-mediated thrombotic thrombocytopenic purpura (TTP). COVID-19 diagnosis coincided with a new diagnosis of a haematological malignancy in four patients. Among patients, 82% were on systemic anti-cancer therapy (SACT) at the time of COVID-19 diagnosis. Of hospitalised patients, 37% (19/51) died while all four outpatients recovered. Risk factors for severe disease or mortality were similar to those in other published cohorts. Raised C-reactive protein at diagnosis predicted an aggressive clinical course. The majority of patients recovered from COVID-19, despite receiving recent SACT. This suggests that SACT, where urgent, should be administered despite intercurrent COVID-19 infection, which should be managed according to standard pathways. Delay or modification of therapy should be considered on an individual basis. Long-term follow-up studies in larger patient cohorts are required to assess the efficacy of treatment strategies employed during the pandemic.
    MeSH term(s) Adult ; Age Factors ; Aged ; Aged, 80 and over ; Antineoplastic Agents/administration & dosage ; Antineoplastic Agents/therapeutic use ; Blacks ; COVID-19/complications ; COVID-19/mortality ; COVID-19/therapy ; Comorbidity ; Cross Infection/complications ; Female ; Hematologic Diseases/complications ; Hematologic Diseases/drug therapy ; Hematologic Diseases/mortality ; Hematologic Diseases/therapy ; Hematopoietic Stem Cell Transplantation ; Humans ; Immunotherapy ; Leukemia/complications ; Leukemia/drug therapy ; Leukemia/mortality ; London/epidemiology ; Lymphoma/complications ; Lymphoma/drug therapy ; Lymphoma/mortality ; Male ; Middle Aged ; Respiration, Artificial ; Retrospective Studies ; Risk Factors ; SARS-CoV-2 ; Thrombophilia/drug therapy ; Thrombophilia/etiology ; Treatment Outcome ; Young Adult
    Chemical Substances Antineoplastic Agents
    Keywords covid19
    Language English
    Publishing date 2020-08-12
    Publishing country England
    Document type Journal Article
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.17027
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article ; Online: Response to 'Impact of immunosuppression on mortality in critically ill COVID-19 patients'.

    Fox, Thomas A / Troy-Barnes, Ethan / Kirkwood, Amy A / Chan, Wei Y / Day, James W / Chavda, Selina J / Kumar, Emil A / David, Kate / Tomkins, Oliver / Sanchez, Emilie / Scully, Marie / Khwaja, Asim / Lambert, Jonathan / Singer, Mervyn / Roddie, Claire / Morris, Emma C / Yong, Kwee L / Thomson, Kirsty J / Ardeshna, Kirit M

    British journal of haematology

    2020  Volume 191, Issue 3, Page(s) 505–506

    MeSH term(s) Betacoronavirus ; COVID-19 ; Coronavirus Infections ; Critical Illness ; Humans ; Pandemics ; Pneumonia, Viral ; SARS-CoV-2
    Keywords covid19
    Language English
    Publishing date 2020-10-26
    Publishing country England
    Document type Journal Article ; Comment
    ZDB-ID 80077-6
    ISSN 1365-2141 ; 0007-1048
    ISSN (online) 1365-2141
    ISSN 0007-1048
    DOI 10.1111/bjh.17110
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Successful remission induction therapy with gilteritinib in a patient with de novo FLT3-mutated acute myeloid leukaemia and severe COVID-19

    Wilson, Andrew J / Troy-Barnes, Ethan / Subhan, Maryam / Clark, Fiona / Gupta, Rajeev / Fielding, Adele K / Kottaridis, Panagiotis / Mansour, Marc R / O039, / Nions, Jenny / Payne, Elspeth / Chavda, Naina / Baker, Robert / Thomson, Kirsty / Khwaja, Asim

    Br. j. haematol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #614297
    Database COVID19

    Kategorien

  8. Article: Response to 'Impact of immunosuppression on mortality in critically ill COVID-19 patients'

    Fox, Thomas A / Troy-Barnes, Ethan / Kirkwood, Amy A / Chan, Wei Y / Day, James W / Chavda, Selina J / Kumar, Emil A / David, Kate / Tomkins, Oliver / Sanchez, Emilie / Scully, Marie / Khwaja, Asim / Lambert, Jonathan / Singer, Mervyn / Roddie, Claire / Morris, Emma C / Yong, Kwee L / Thomson, Kirsty J / Ardeshna, Kirit M

    Br J Haematol

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #889708
    Database COVID19

    Kategorien

  9. Article: Clinical outcomes and risk factors for severe COVID-19 in patients with haematological disorders receiving chemo- or immunotherapy

    Fox, Thomas A / Troy-Barnes, Ethan / Kirkwood, Amy A / Chan, Wei Yee / Day, James W / Chavda, Selina J / Kumar, Emil A / David, Kate / Tomkins, Oliver / Sanchez, Emilie / Scully, Marie / Khwaja, Asim / Lambert, Jonathan / Singer, Mervyn / Roddie, Claire / Morris, Emma C / Yong, Kwee L / Thomson, Kirsty J / Ardeshna, Kirit M

    Br. j. haematol

    Abstract: Haematology patients receiving chemo- or immunotherapy are considered to be at greater risk of COVID-19-related morbidity and mortality. We aimed to identify risk factors for COVID-19 severity and assess outcomes in patients where COVID-19 complicated ... ...

    Abstract Haematology patients receiving chemo- or immunotherapy are considered to be at greater risk of COVID-19-related morbidity and mortality. We aimed to identify risk factors for COVID-19 severity and assess outcomes in patients where COVID-19 complicated the treatment of their haematological disorder. A retrospective cohort study was conducted in 55 patients with haematological disorders and COVID-19, including 52 with malignancy, two with bone marrow failure and one immune-mediated thrombotic thrombocytopenic purpura (TTP). COVID-19 diagnosis coincided with a new diagnosis of a haematological malignancy in four patients. Among patients, 82% were on systemic anti-cancer therapy (SACT) at the time of COVID-19 diagnosis. Of hospitalised patients, 37% (19/51) died while all four outpatients recovered. Risk factors for severe disease or mortality were similar to those in other published cohorts. Raised C-reactive protein at diagnosis predicted an aggressive clinical course. The majority of patients recovered from COVID-19, despite receiving recent SACT. This suggests that SACT, where urgent, should be administered despite intercurrent COVID-19 infection, which should be managed according to standard pathways. Delay or modification of therapy should be considered on an individual basis. Long-term follow-up studies in larger patient cohorts are required to assess the efficacy of treatment strategies employed during the pandemic.
    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #650898
    Database COVID19

    Kategorien

  10. Article ; Online: Clinical outcomes and risk factors for severe COVID‐19 in patients with haematological disorders receiving chemo‐ or immunotherapy

    Fox, Thomas A. / Troy‐Barnes, Ethan / Kirkwood, Amy A. / Chan, Wei Yee / Day, James W. / Chavda, Selina J. / Kumar, Emil A. / David, Kate / Tomkins, Oliver / Sanchez, Emilie / Scully, Marie / Khwaja, Asim / Lambert, Jonathan / Singer, Mervyn / Roddie, Claire / Morris, Emma C. / Yong, Kwee L. / Thomson, Kirsty J. / Ardeshna, Kirit M.

    British Journal of Haematology ; ISSN 0007-1048 1365-2141

    2020  

    Keywords Hematology ; covid19
    Language English
    Publisher Wiley
    Publishing country us
    Document type Article ; Online
    DOI 10.1111/bjh.17027
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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