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  1. Article: Enlarged and uncommon indications for ALPPS-where do we stand?

    Truant, Stéphanie

    Hepatobiliary surgery and nutrition

    2022  Volume 11, Issue 5, Page(s) 743–745

    Language English
    Publishing date 2022-01-28
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-22-371
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Kinetics of remnant liver volume and function after a major hepatectomy.

    Truant, Stéphanie / El Amrani, Mehdi / Pruvot, François-René

    Hepatobiliary surgery and nutrition

    2023  Volume 12, Issue 6, Page(s) 975–977

    Language English
    Publishing date 2023-11-08
    Publishing country China (Republic : 1949- )
    Document type Editorial ; Comment
    ZDB-ID 2812398-0
    ISSN 2304-389X ; 2304-3881
    ISSN (online) 2304-389X
    ISSN 2304-3881
    DOI 10.21037/hbsn-23-469
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  3. Article ; Online: Robotic liver resection in the posterosuperior segments as a way to extent the mini-invasive arsenal: a comparison with transthoracic laparoscopic approach.

    Denglos, Pauline / Truant, Stéphanie / El Amrani, Mehdi / Millet, Guillaume

    Surgical endoscopy

    2023  Volume 37, Issue 6, Page(s) 4478–4485

    Abstract: Background: The field of robotic liver resection (RLR) has developed in the past decades. This technique seems to improve the access to the posterosuperior (PS) segments. Evidence of a possible advantage over transthoracic laparoscopy (TTL) is not yet ... ...

    Abstract Background: The field of robotic liver resection (RLR) has developed in the past decades. This technique seems to improve the access to the posterosuperior (PS) segments. Evidence of a possible advantage over transthoracic laparoscopy (TTL) is not yet available. We aimed to compare RLR to TTL for tumors located in the PS segments of the liver in terms of feasibility, difficulty scoring, and outcome.
    Methods: This retrospective study compared patients undergoing robotic liver resections and transthoracic laparoscopic resections of the PS segments between January 2016 and December 2022 in a high-volume HPB center. Patients' characteristics, perioperative outcomes, and postoperative complications were evaluated.
    Results: In total, 30 RLR and 16 TTL were included. Only wedge resections were performed in the TTL group, while 43% of the patients in the RLR group had an anatomical resection (p < 0.001). The difficulty score according to the IWATE difficulty scoring system was significantly higher in the RLR group (p < 0.001). Total operative time was similar between the two groups. Complication rates, either overall or major, were comparable between the two techniques and hospital stay was significantly shorter in the RLR group. Patients in the TTL group were found to have more pulmonary complications (p = 0.01).
    Conclusion: RLR may provide some advantages over TTL for the resection of tumors located in the PS segments.
    MeSH term(s) Humans ; Liver Neoplasms/surgery ; Liver Neoplasms/pathology ; Retrospective Studies ; Robotic Surgical Procedures ; Hepatectomy/methods ; Laparoscopy/methods ; Postoperative Complications/epidemiology ; Postoperative Complications/etiology ; Postoperative Complications/surgery ; Length of Stay
    Language English
    Publishing date 2023-02-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639039-0
    ISSN 1432-2218 ; 0930-2794
    ISSN (online) 1432-2218
    ISSN 0930-2794
    DOI 10.1007/s00464-023-09919-6
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2214: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)

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  4. Article ; Online: ASO Author Reflections: Usage of Single Photon Emission CT (SPECT) Hepatobiliary Scintigraphy to Detect the Impact of Chemotherapy-Associated Liver Injuries (CALI) on Liver Function Before a Major Hepatectomy.

    Truant, Stéphanie / Pruvot, François-René

    Annals of surgical oncology

    2020  Volume 27, Issue Suppl 3, Page(s) 882–883

    MeSH term(s) Hepatectomy ; Humans ; Liver/diagnostic imaging ; Radionuclide Imaging ; Radiopharmaceuticals ; Tomography, Emission-Computed, Single-Photon
    Chemical Substances Radiopharmaceuticals
    Language English
    Publishing date 2020-08-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1200469-8
    ISSN 1534-4681 ; 1068-9265
    ISSN (online) 1534-4681
    ISSN 1068-9265
    DOI 10.1245/s10434-020-08996-4
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 4042: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article ; Online: Management of pancreatic ascites complicating alcoholic chronic pancreatitis.

    Schneider Bordat, L / El Amrani, M / Truant, S / Branche, J / Zerbib, P

    Journal of visceral surgery

    2021  Volume 158, Issue 5, Page(s) 370–377

    Abstract: Introduction: Pancreatic ascites (PA) is an unusual and little studied complication of chronic alcoholic pancreatitis. Management is complex and is based mainly on empirical data. The aim of this retrospective work was to analyse the management of PA at ...

    Abstract Introduction: Pancreatic ascites (PA) is an unusual and little studied complication of chronic alcoholic pancreatitis. Management is complex and is based mainly on empirical data. The aim of this retrospective work was to analyse the management of PA at our centre.
    Patients and methods: A total of 24 patients with PA complicating chronic alcoholic pancreatitis were managed at the Lille University Hospital between 2004 and 2018. Treatment was initially medical and then, in case of failure, interventional (endoscopic, radiological and/or surgical). Data regarding epidemiology, therapeutic and follow-up data were collected retrospectively.
    Results: Twenty-four patients were analysed; median follow-up was 18.5 months [6.75-34.25]. Exclusively medical treatment was effective in three of four patients, but, based on intention to treat, medical therapy alone was effective in only two out of 24 patients. Of 17 patients treated endoscopically, treatment was successful in 15 of them. Of the 15 who underwent surgery, external surgical drainage was effective in 13. Multimodal treatment, initiated after 6.5 days [4-13.5] of medical treatment, was effective in 12 out of 14 patients. In total, 21 patients were successfully treated (87%) with a morbidity rate of 79% and a mortality rate of 12.5% (n=3).
    Conclusion: PA gives rise to significant morbidity and mortality. Conservative medical treatment has only a limited role. If medical treatment fails, endoscopic and then surgical treatment allow a favourable outcome in more than 80% of patients.
    MeSH term(s) Ascites/etiology ; Ascites/therapy ; Drainage/adverse effects ; Humans ; Pancreatic Pseudocyst/etiology ; Pancreatitis, Alcoholic/complications ; Pancreatitis, Alcoholic/therapy ; Retrospective Studies ; Treatment Outcome
    Language English
    Publishing date 2021-01-16
    Publishing country France
    Document type Journal Article
    ISSN 1878-7886
    ISSN (online) 1878-7886
    DOI 10.1016/j.jviscsurg.2020.11.015
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  6. Article ; Online: Is there still a room to improve the safety of ALPPS procedure? A new technical note.

    Truant, S / Pruvot, F-R

    European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

    2015  Volume 41, Issue 11, Page(s) 1554–1555

    MeSH term(s) Bile Duct Neoplasms/surgery ; Carcinoma/surgery ; Colorectal Neoplasms/pathology ; Female ; Gallbladder Neoplasms/surgery ; Hepatectomy/methods ; Humans ; Liver/surgery ; Liver Failure/prevention & control ; Liver Neoplasms/surgery ; Male ; Portal Vein/surgery
    Language English
    Publishing date 2015-11
    Publishing country England
    Document type Comment ; Letter
    ZDB-ID 632519-1
    ISSN 1532-2157 ; 0748-7983
    ISSN (online) 1532-2157
    ISSN 0748-7983
    DOI 10.1016/j.ejso.2015.08.151
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    In stock of ZB MED Cologne/Königswinter

    Zs.A 1149: Show issues Location:
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    Jg. 1995 - 2021: Lesesall (1.OG)
    ab Jg. 2022: Lesesaal (EG)
    Zs.MO 549: Show issues

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  7. Article ; Online: Response to Comment on: "Liver Venous Deprivation or Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy? A Retrospective Multicentric Study": How to Choose a Way to Enhance the Growth of Future Liver Remnant in the Future.

    Truant, Stéphanie / Chébaro, Alexandre / Pruvot, Francois-René

    Annals of surgery

    2021  Volume 276, Issue 6, Page(s) e1116–e1117

    MeSH term(s) Humans ; Hepatectomy ; Portal Vein/surgery ; Retrospective Studies ; Liver/surgery ; Liver/physiology ; Hepatic Veins ; Ligation
    Language English
    Publishing date 2021-11-16
    Publishing country United States
    Document type Multicenter Study ; Journal Article ; Comment
    ZDB-ID 340-2
    ISSN 1528-1140 ; 0003-4932
    ISSN (online) 1528-1140
    ISSN 0003-4932
    DOI 10.1097/SLA.0000000000005299
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    In stock of ZB MED Cologne/Königswinter

    Uk I Zs.35/1: Show issues Location:
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    ab Jg. 2022: Lesesaal (EG)

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  8. Article ; Online: Adjuvant chemotherapy omission after pancreatic cancer resection: a French nationwide study.

    Poiraud, Charles / Lenne, Xavier / Bruandet, Amélie / Theis, Didier / Bertrand, Nicolas / Turpin, Anthony / Truant, Stephanie / El Amrani, Mehdi

    World journal of surgical oncology

    2024  Volume 22, Issue 1, Page(s) 123

    Abstract: Background: Adjuvant chemotherapy (AC) improves the prognosis after pancreatic ductal adenocarcinoma (PDAC) resection. However, previous studies have shown that a large proportion of patients do not receive or complete AC. This national study examined ... ...

    Abstract Background: Adjuvant chemotherapy (AC) improves the prognosis after pancreatic ductal adenocarcinoma (PDAC) resection. However, previous studies have shown that a large proportion of patients do not receive or complete AC. This national study examined the risk factors for the omission or interruption of AC.
    Methods: Data of all patients who underwent pancreatic surgery for PDAC in France between January 2012 and December 2017 were extracted from the French National Administrative Database. We considered "omission of adjuvant chemotherapy" (OAC) all patients who failed to receive any course of gemcitabine within 12 postoperative weeks and "interruption of AC" (IAC) was defined as less than 18 courses of AC.
    Results: A total of 11 599 patients were included in this study. Pancreaticoduodenectomy was the most common procedure (76.3%), and 31% of the patients experienced major postoperative complications. OACs and IACs affected 42% and 68% of the patients, respectively. Ultimately, only 18.6% of the cohort completed AC. Patients who underwent surgery in a high-volume centers were less affected by postoperative complications, with no impact on the likelihood of receiving AC. Multivariate analysis showed that age ≥ 80 years, Charlson comorbidity index (CCI) ≥ 4, and major complications were associated with OAC (OR = 2.19; CI
    Conclusion: Sequence surgery followed by chemotherapy is associated with a high dropout rate, especially in octogenarian and comorbid patients.
    MeSH term(s) Humans ; Female ; Male ; Pancreatic Neoplasms/surgery ; Pancreatic Neoplasms/drug therapy ; Pancreatic Neoplasms/pathology ; Aged ; Chemotherapy, Adjuvant/statistics & numerical data ; Chemotherapy, Adjuvant/methods ; France/epidemiology ; Carcinoma, Pancreatic Ductal/surgery ; Carcinoma, Pancreatic Ductal/drug therapy ; Carcinoma, Pancreatic Ductal/pathology ; Middle Aged ; Aged, 80 and over ; Prognosis ; Pancreatectomy/statistics & numerical data ; Follow-Up Studies ; Pancreaticoduodenectomy/statistics & numerical data ; Pancreaticoduodenectomy/methods ; Postoperative Complications/epidemiology ; Survival Rate ; Retrospective Studies ; Gemcitabine ; Risk Factors ; Deoxycytidine/analogs & derivatives ; Deoxycytidine/therapeutic use
    Chemical Substances Gemcitabine ; Deoxycytidine (0W860991D6)
    Language English
    Publishing date 2024-05-06
    Publishing country England
    Document type Journal Article
    ZDB-ID 2118383-1
    ISSN 1477-7819 ; 1477-7819
    ISSN (online) 1477-7819
    ISSN 1477-7819
    DOI 10.1186/s12957-024-03393-7
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  9. Article ; Online: Sarcopenia does not affect liver regeneration and postoperative course after a major hepatectomy. A prospective study on 125 patients using CT volumetry and HIDA scintigraphy.

    Fulbert, Maxence / El Amrani, Mehdi / Baillet, Clio / Lecolle, Katia / Ernst, Olivier / Louvet, Alexandre / Pruvot, François-René / Huglo, Damien / Truant, Stéphanie

    Clinics and research in hepatology and gastroenterology

    2024  Volume 48, Issue 5, Page(s) 102332

    Abstract: Background & objectives: Sarcopenia is a morbi-mortality risk factor in digestive surgery, though its impact after major hepatectomy (MH) remains unknown. This prospective pilot study investigated whether volume and function of a regenerating liver is ... ...

    Abstract Background & objectives: Sarcopenia is a morbi-mortality risk factor in digestive surgery, though its impact after major hepatectomy (MH) remains unknown. This prospective pilot study investigated whether volume and function of a regenerating liver is influenced by body composition.
    Methods: From 2011 to 2016, 125 consecutive patients had computed tomography and 99mTc-labelled-mebrofenin SPECT-scintigraphy before and after MH at day 7 and 1 month for measurements of liver volumes and functions. L3 vertebra muscle mass identified sarcopenia. Primary endpoint was the impact of sarcopenia on regeneration capacities (i.e. volume/function changes and post-hepatectomy liver failure (PHLF) rate). Secondary endpoint was 3-month morbi-mortality.
    Results: Sarcopenic patients (SP; N = 69) were significantly older than non-sarcopenic (NSP), with lower BMI and more malignancies, but with comparable liver function/volume at baseline. Postoperatively, SP showed higher rates of ISGLS_PHLF (24.6 % vs 10.9 %; p = 0.05) but with comparable rates of severe morbidity (23.2 % vs 16.4 %; p = 0.35), overall (8.7 % vs 3.6 %; p = 0.3) and PHLF-related mortality (8,7 % vs 1.8 %; p = 0.075). After matching on the extent of resection or using propensity score, regeneration and PHLF rates were similar.
    Conclusion: This prospective study using first sequential SPECT-scintigraphy showed that sarcopenia by itself does not affect liver regeneration capacities and short-term postoperative course after MH.
    MeSH term(s) Humans ; Sarcopenia/diagnostic imaging ; Sarcopenia/etiology ; Sarcopenia/complications ; Prospective Studies ; Male ; Hepatectomy ; Female ; Liver Regeneration/physiology ; Aged ; Middle Aged ; Pilot Projects ; Tomography, X-Ray Computed ; Tomography, Emission-Computed, Single-Photon ; Organ Size ; Postoperative Complications/etiology ; Postoperative Complications/diagnostic imaging ; Radiopharmaceuticals ; Organotechnetium Compounds ; Imino Acids ; Liver Failure/diagnostic imaging ; Liver Failure/etiology ; Liver Failure/surgery ; Aniline Compounds ; Glycine
    Chemical Substances Radiopharmaceuticals ; Organotechnetium Compounds ; Imino Acids ; technetium Tc 99m mebrofenin (F2NQ468L52) ; Aniline Compounds ; Glycine (TE7660XO1C)
    Language English
    Publishing date 2024-04-02
    Publishing country France
    Document type Journal Article
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2024.102332
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  10. Article ; Online: Good outcome of liver transplantation in patients with pre-existing renal cell carcinoma.

    Lassailly, G / Ningarhari, M / Dumortier, J / Lafforgue, C / Bouye, S / Amrani, M El / Lebuffe, G / Villers, A / Truant, S / Mathurin, P / Louvet, A / Boillot, O / Boleslawski, E / Dharancy, S

    Clinics and research in hepatology and gastroenterology

    2023  Volume 48, Issue 1, Page(s) 102266

    Abstract: The presence of a pre-existing or recent extra-hepatic solid tumor was considered for a long time as an absolute contraindication to liver transplantation, by fear of futility with an unacceptable increase in non-liver-related mortality. However, cancer- ... ...

    Abstract The presence of a pre-existing or recent extra-hepatic solid tumor was considered for a long time as an absolute contraindication to liver transplantation, by fear of futility with an unacceptable increase in non-liver-related mortality. However, cancer-related mortality in solid malignancies is heterogeneous, and experts suggest that case-by-case multidisciplinary decisions should be made. Here, we report the cases of 3 patients with favorable oncological and liver outcome in patients with renal cell carcinoma detected during pre-transplant evaluation that nonetheless underwent liver transplantation.
    MeSH term(s) Humans ; Carcinoma, Renal Cell/surgery ; Liver Transplantation ; Liver Neoplasms/surgery ; Kidney Neoplasms/surgery ; Treatment Outcome
    Language English
    Publishing date 2023-12-13
    Publishing country France
    Document type Letter
    ZDB-ID 2594333-9
    ISSN 2210-741X ; 2210-7401
    ISSN (online) 2210-741X
    ISSN 2210-7401
    DOI 10.1016/j.clinre.2023.102266
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