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  1. AU="Trujillo, Adriana M"
  2. AU=Uitto Jouni
  3. AU="Williams, Rachel L"
  4. AU=Dirix Piet
  5. AU="Park, Hyunhee"
  6. AU="Vivian de los Ríos"
  7. AU="Nadadur, Srikanth S"
  8. AU="Molina-Recio, Guillermo"
  9. AU="Rajan, Aswani"
  10. AU="Brittany Grzybowski"
  11. AU=Barkan Dalit AU=Barkan Dalit

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  1. Artikel ; Online: Susceptibility to endemic Aedes-borne viruses among pregnant women in Risaralda, Colombia.

    Cardona-Ospina, Jaime A / Trujillo, Adriana M / Jiménez-Posada, Erika V / Sepúlveda-Arias, Juan C / Tabares-Villa, Fredy A / Altieri-Rivera, Joanne S / Monsalve, Alejandro / Restrepo-Chica, Juliana / Osorio, Daniela / Espinoza, Daniel / Zhu, Yerun / Castrillón-Spitia, Juan D / Henao-SanMartin, Valentina / Murillo-Garcia, David R / Millán, Natalia / Olaya, Sandra X / Valencia-Montoya, Ana M / Bedoya-Arias, Hugo A / Villamizar-Peña, Rhuvi /
    Gutierrez-Ocampo, Estefanía / Holguin-Rivera, Yeimer / Cortés-Bonilla, Isabella / Cardona-Trujillo, Maria C / García-Barco, Alejandra / Bonilla-Aldana, D Katterine / Lagos-Grisales, Guillermo J / Rodríguez-Morales, Alfonso J / Collins, Matthew H

    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

    2022  Band 122, Seite(n) 832–840

    Abstract: Objectives: Aedes-borne viruses (ABV) affect humans on every inhabited continent and frequently cause epidemics. Recent epidemics of chikungunya and Zika viruses (ZIKV) highlight that preparedness for future epidemics requires assessment of ... ...

    Abstract Objectives: Aedes-borne viruses (ABV) affect humans on every inhabited continent and frequently cause epidemics. Recent epidemics of chikungunya and Zika viruses (ZIKV) highlight that preparedness for future epidemics requires assessment of susceptibility, particularly among high-risk groups. We sought to determine immunity against the three major circulating ABV among pregnant women in an ABV-endemic area of Colombia.
    Methods: A cross-sectional seroprevalence study was performed, enrolling women presenting to Labor and Delivery. Cord blood and maternal peripheral blood samples were obtained. IgG seroprevalence to flaviviruses and chikungunya was determined by ELISA. An abbreviated neutralization test was used to estimate the frequency and magnitude of immunity to Zika and four dengue serotypes. Cluster analyses explored epidemiologic factors associated with seroprevalence.
    Results: Most women exhibited high levels of neutralizing antibodies to one or more ABV; however, nearly 20% were seronegative for flaviviruses. Our research took place after the epidemic peak of the ZIKV outbreak in Colombia in 2016. However, only 20% of pregnant women had high levels of Zika-neutralizing antibodies consistent with likely protective immunity to ZIKV.
    Conclusion: Hence, a high proportion of pregnant women in Risaralda remain susceptible to one or more ABV including the teratogenic ZIKV, indicating a risk for future epidemics in this region.
    Mesh-Begriff(e) Aedes ; Animals ; Antibodies, Neutralizing ; Antibodies, Viral ; Chikungunya Fever/epidemiology ; Colombia/epidemiology ; Cross-Sectional Studies ; Dengue/epidemiology ; Dengue Virus ; Female ; Humans ; Pregnancy ; Pregnant Women ; Seroepidemiologic Studies ; Zika Virus ; Zika Virus Infection
    Chemische Substanzen Antibodies, Neutralizing ; Antibodies, Viral
    Sprache Englisch
    Erscheinungsdatum 2022-07-09
    Erscheinungsland Canada
    Dokumenttyp Journal Article
    ZDB-ID 1331197-9
    ISSN 1878-3511 ; 1201-9712
    ISSN (online) 1878-3511
    ISSN 1201-9712
    DOI 10.1016/j.ijid.2022.07.017
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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  2. Artikel ; Online: Diagnosis and outcomes of pregnant women with Zika virus infection in two municipalities of Risaralda, Colombia: Second report of the ZIKERNCOL study.

    Rodriguez-Morales, Alfonso J / Cardona-Ospina, Jaime A / Ramirez-Jaramillo, Valeria / Gaviria, Javier A / González-Moreno, Gloria María / Castrillón-Spitia, Juan D / López-Villegas, Alejandra / Morales-Jiménez, Estefania / Ramírez-Zapata, Valentina / Rueda-Merchán, German Eduardo / Trujillo, Adriana M / Tabares-Villa, Fredy A / Henao-SanMartin, Valentina / Murillo-Garcia, David R / Herrera-Soto, Johana Andrea / Buitrago-Cañas, Marta Liliana / Collins, Matthew H / Sepúlveda-Arias, Juan Carlos / Londoño, José J /
    Bedoya-Rendón, Héctor D / de Jesús Cárdenas-Pérez, Javier / Olaya, Sandra X / Lagos-Grisales, Guillermo J

    Travel medicine and infectious disease

    2018  Band 25, Seite(n) 20–25

    Abstract: Background: Zika virus (ZIKV) infection has emerged as a significant threat for pregnant women and newborns in populations living in or visiting Latin America. We previously reported a preliminary analysis in Sucre, Colombia, as the first group of ... ...

    Abstract Background: Zika virus (ZIKV) infection has emerged as a significant threat for pregnant women and newborns in populations living in or visiting Latin America. We previously reported a preliminary analysis in Sucre, Colombia, as the first group of pregnant women with RT-PCR-confirmed ZIKV (ZIKa enEmbarazadas yReciénNacidos enCOLombia, ZIKERNCOL).
    Methods: In this second report, findings of the first 86 pregnant women from La Virginia and Dosquebradas (municipalities), Risaralda, Colombia, with RT-PCR-confirmed ZIKV infection are reported. Clinical, demographical and obstetrical findings are described.
    Results: All women reported ZIKV symptoms during pregnancy: 79.1% rash, 55.8% fever, among others. In addition to ZIKV, RT-PCR was positive for dengue in 18.6%; 45.3% Dengue IgM+; 5.8% RT-PCR positive for chikungunya; 3.6% Chikungunya IgM+. STORCH screening in mother: 11.6% IgG + anti-Toxoplasma gondii, 6% IgG + anti-rubella, 4.7% IgG + CMV. The rest of STORCH tests were negative. Microcephaly was observed in 2.4% of the newborns. No calcifications or other CNS alterations were detected. One newborn had cleft palate and one had bilateral renal ectopy.
    Conclusions: The rate of microcephaly in our cohort was consistent with other studies. Pregnant women in endemic areas should be followed and tested according to standard protocols, and asymptomatic ZIKV infection should be considered. Long-term follow-up of children is required in the congenital Zika syndrome (CZS) assessment.
    Mesh-Begriff(e) Adolescent ; Adult ; Antibodies, Viral ; Chikungunya Fever/immunology ; Cohort Studies ; Colombia/epidemiology ; Dengue/diagnosis ; Dengue/immunology ; Female ; Humans ; Immunoglobulin G ; Infant, Newborn ; Microcephaly/virology ; Pregnancy ; Pregnancy Complications, Infectious/virology ; Retrospective Studies ; Rubella/immunology ; Toxoplasmosis ; Young Adult ; Zika Virus Infection/diagnosis ; Zika Virus Infection/epidemiology
    Chemische Substanzen Antibodies, Viral ; Immunoglobulin G
    Sprache Englisch
    Erscheinungsdatum 2018-06-09
    Erscheinungsland Netherlands
    Dokumenttyp Journal Article
    ZDB-ID 2170891-5
    ISSN 1873-0442 ; 1477-8939
    ISSN (online) 1873-0442
    ISSN 1477-8939
    DOI 10.1016/j.tmaid.2018.06.006
    Datenquelle MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 6236: Hefte anzeigen Standort:
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