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  1. Article ; Online: Extracorporeal life support in infarct-related cardiogenic shock-critical view on study results and consequences for shock therapy.

    Trummer, Georg / Boeken, Udo / Kaluza, Mirko / Siepe, Matthias / Böning, Andreas

    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery

    2024  Volume 65, Issue 2

    MeSH term(s) Humans ; Shock, Cardiogenic/therapy ; Extracorporeal Membrane Oxygenation/methods ; Convulsive Therapy ; Retrospective Studies
    Language English
    Publishing date 2024-02-01
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639293-3
    ISSN 1873-734X ; 1010-7940 ; 1567-4258
    ISSN (online) 1873-734X
    ISSN 1010-7940 ; 1567-4258
    DOI 10.1093/ejcts/ezae025
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 2303: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  2. Book ; Thesis: Die distale Radiusfraktur, Verlaufskontrolle im Röntgenbild und im MR-Tomogramm

    Trummer, Georg

    1994  

    Author's details vorgelegt von Georg Trummer
    Language German
    Size 52 Bl. : Ill., graph. Darst.
    Document type Book ; Thesis
    Thesis / German Habilitation thesis Heidelberg, Univ., Diss., 1995
    HBZ-ID HT006670870
    Database Catalogue ZB MED Medicine, Health

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    Shelf markLoan statusLocation
    95 E 1240 order for loan Magazin

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  3. Article ; Online: Pervasive Platelet Secretion Defects in Patients with Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2).

    Kalbhenn, Johannes / Pooth, Jan-Steffen / Trummer, Georg / Kranzhöfer, David / Schlagenhauf, Axel / Zieger, Barbara

    Cells

    2023  Volume 12, Issue 1

    Abstract: Critically ill COVID-19 patients suffer from thromboembolic as well as bleeding events. Endothelial dysfunction, spiking of von Willebrand factor (vWF), and excessive cytokine signaling result in coagulopathy associated with substantial activation of ... ...

    Abstract Critically ill COVID-19 patients suffer from thromboembolic as well as bleeding events. Endothelial dysfunction, spiking of von Willebrand factor (vWF), and excessive cytokine signaling result in coagulopathy associated with substantial activation of plasmatic clotting factors. Thrombocytopenia secondary to extensive platelet activation is a frequent finding, but abnormal platelet dysfunction may also exist in patients with normal platelet counts. In this study, we performed analyses of platelet function and of von Willebrand factor in critically ill COVID-19 patients (
    MeSH term(s) Humans ; von Willebrand Factor/metabolism ; SARS-CoV-2/metabolism ; Critical Illness ; Platelet Aggregation ; COVID-19/complications ; Hemostasis ; Thrombocytopenia/complications ; Collagen/metabolism
    Chemical Substances von Willebrand Factor ; Collagen (9007-34-5)
    Language English
    Publishing date 2023-01-03
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2661518-6
    ISSN 2073-4409 ; 2073-4409
    ISSN (online) 2073-4409
    ISSN 2073-4409
    DOI 10.3390/cells12010193
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  4. Book ; Online ; Thesis: <dc:title>Extrakorporale Reanimation nach Herz-Kreislauf-Stillstand im realitätsnahen Schweinemodell: Auswirkungen der kontrollierten, automatisierten Ganzkörperreperfusion im Vergleich zur konventionellen extrakorporalen Zirkulation</dc:title>

    Brixius, Sam [Verfasser] / Trummer, Georg [Akademischer Betreuer] / Trummer, Georg [Sonstige] / Ulbrich, Felix [Sonstige]

    2022  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
    Database Digital theses on the web

    Full text online

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  5. Article ; Online: Application of cardiac surgery techniques to improve the results of cardiopulmonary resuscitation after cardiac arrest: Controlled automated reperfusion of the whole body.

    Beyersdorf, Friedhelm / Trummer, Georg / Benk, Christoph / Pooth, Jan-Steffen

    JTCVS open

    2021  Volume 8, Page(s) 47–52

    Language English
    Publishing date 2021-10-20
    Publishing country Netherlands
    Document type Editorial
    ISSN 2666-2736
    ISSN (online) 2666-2736
    DOI 10.1016/j.xjon.2021.10.006
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  6. Article ; Online: Extracorporeal Membrane Oxygenation.

    Bernhardt, Alexander M / Schrage, Benedikt / Schroeder, Ines / Trummer, Georg / Westermann, Dirk / Reichenspurner, Hermann

    Deutsches Arzteblatt international

    2022  Volume 119, Issue 13, Page(s) 235–244

    Abstract: Background: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) and veno-arterial extracorporeal membrane oxygenation (VA-ECMO), also known as extracorporeal life support (ECLS), can both be used to treat patients with acute pulmonary or ... ...

    Abstract Background: Veno-venous extracorporeal membrane oxygenation (VV-ECMO) and veno-arterial extracorporeal membrane oxygenation (VA-ECMO), also known as extracorporeal life support (ECLS), can both be used to treat patients with acute pulmonary or cardiovascular failure.
    Methods: This review is based on publications retrieved by a selective search in PubMed on the topics of cardiogenic shock and acute pulmonary failure, also known as the acute respiratory distress syndrome (ARDS), as well as on ECMO. Attention was given chiefly to randomized, controlled trials and guidelines.
    Results: Initial findings from prospective, randomized trials of VV-ECMO are now available. Trials of ECLS therapy are now in progress or planned. A meta-analysis of two randomized, controlled trials of VV-ECMO for ARDS revealed more frequent survival 90 days after randomization among patients treated with VV-ECMO, compared to the control groups (36% vs. 48%; RR = 0.75 [95% confidence interval 0.6; 0.94]). For selected patients, after evaluation of the benefit-risk profile, VV-ECMO is a good treatment method for severe pulmonary failure, and ECLS for cardiogenic shock and resuscitation. The goal is to secure the circulation so that native heart function can be stabilized in the patient's further course or a permanent left-heart support system can be implanted, or else to support lung function until recovery.
    Conclusion: ECMO is a valid option in selected patients when conservative treatment has failed.
    MeSH term(s) Extracorporeal Membrane Oxygenation ; Humans ; Prospective Studies ; Respiratory Distress Syndrome/therapy ; Respiratory Insufficiency/etiology ; Retrospective Studies ; Shock, Cardiogenic/etiology ; Shock, Cardiogenic/therapy
    Language English
    Publishing date 2022-01-16
    Publishing country Germany
    Document type Journal Article ; Review
    ZDB-ID 2406159-1
    ISSN 1866-0452 ; 1866-0452
    ISSN (online) 1866-0452
    ISSN 1866-0452
    DOI 10.3238/arztebl.m2022.0068
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  7. Article ; Online: First responder systems can stay operational under pandemic conditions: results of a European survey during the COVID-19 pandemic.

    Metelmann, Camilla / Metelmann, Bibiana / Müller, Michael P / Böttiger, Bernd W / Trummer, Georg / Thies, Karl Christian

    Scandinavian journal of trauma, resuscitation and emergency medicine

    2022  Volume 30, Issue 1, Page(s) 10

    Abstract: Background: Dispatching first responders (FR) to out-of-hospital cardiac arrest in addition to the emergency medical service has shown to increase survival. The promising development of FR systems over the past years has been challenged by the outbreak ... ...

    Abstract Background: Dispatching first responders (FR) to out-of-hospital cardiac arrest in addition to the emergency medical service has shown to increase survival. The promising development of FR systems over the past years has been challenged by the outbreak of COVID-19. Whilst increased numbers and worse outcomes of cardiac arrests during the pandemic suggest a need for expansion of FR schemes, appropriate risk management is required to protect first responders and patients from contracting COVID-19. This study investigated how European FR schemes were affected by the pandemic and what measures were taken to protect patients and responders from COVID-19.
    Methods: To identify FR schemes in Europe we conducted a literature search and a web search. The schemes were contacted and invited to answer an online questionnaire during the second wave of the pandemic (December 2020/ January 2021) in Europe.
    Results: We have identified 135 FR schemes in 28 countries and included responses from 47 FR schemes in 16 countries. 25 schemes reported deactivation due to COVID-19 at some point, whilst 22 schemes continued to operate throughout the pandemic. 39 schemes communicated a pandemic-specific algorithm to their first responders. Before the COVID-19 outbreak 20 FR systems did not provide any personal protective equipment (PPE). After the outbreak 19 schemes still did not provide any PPE. The majority of schemes experienced falling numbers of accepted call outs and decreasing registrations of new volunteers. Six schemes reported of FR having contracted COVID-19 on a mission.
    Conclusions: European FR schemes were considerably affected by the pandemic and exhibited a range of responses to protect patients and responders. Overall, FR schemes saw a decrease in activity, which was in stark contrast to the high demand caused by the increased incidence and mortality of OHCA during the pandemic. Given the important role FR play in the chain of survival, a balanced approach upholding the safety of patients and responders should be sought to keep FR schemes operational.
    MeSH term(s) COVID-19 ; Cardiopulmonary Resuscitation/methods ; Emergency Responders ; Humans ; Out-of-Hospital Cardiac Arrest ; Pandemics ; SARS-CoV-2 ; Surveys and Questionnaires
    Language English
    Publishing date 2022-02-19
    Publishing country England
    Document type Journal Article
    ZDB-ID 2455990-8
    ISSN 1757-7241 ; 1757-7241
    ISSN (online) 1757-7241
    ISSN 1757-7241
    DOI 10.1186/s13049-022-00998-3
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  8. Article ; Online: Extracorporeal Membrane Oxygenation in Intoxication and Overdoses: A Systematic Review.

    Maier, Sven / Rösner, Lisa / Saemann, Lars / Sogl, Jonas / Beyersdorf, Friedhelm / Trummer, Georg / Czerny, Martin / Benk, Christoph

    The Thoracic and cardiovascular surgeon

    2023  

    Abstract: Background:  Extracorporeal membrane oxygenation (ECMO) has been increasingly applied over recent decades to treat severe cardiogenic shock and acute lung failure and cardiac arrest of various causes. Acute intoxication with therapeutic substances or ... ...

    Abstract Background:  Extracorporeal membrane oxygenation (ECMO) has been increasingly applied over recent decades to treat severe cardiogenic shock and acute lung failure and cardiac arrest of various causes. Acute intoxication with therapeutic substances or other chemical substances can cause severe cardiogenic shock or even cardiac arrest. The purpose of this study was to conduct a qualitative systematic review of ECMO use in intoxication and poisoning.
    Methods:  We searched the PubMed, Medline, and Web of Science databases from January 1971 to December 2021 and selected appropriate studies according to our inclusion and exclusion criteria to evaluate the role of ECMO in intoxication and poisoning systematically. Survival at hospital discharge was examined to describe the outcome.
    Results:  The search resulted in 365 publications after removing duplicates. In total, 190 full-text articles were assessed for eligibility. A total of 145 articles from 1985 to 2021 were examined in our final qualitative analysis. A total of 539 (100%) patients were included (mean age: 30.9 ± 16.6 years), with a distribution of
    Conclusion:  When used and reported, ECMO seems to be a valid tool for adult and pediatric patients suffering intoxication from various pharmaceutical and nonpharmaceutical substances due to a high survival rate at hospital discharge.
    Language English
    Publishing date 2023-03-20
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 800050-5
    ISSN 1439-1902 ; 0171-6425 ; 0946-4778 ; 0172-6137
    ISSN (online) 1439-1902
    ISSN 0171-6425 ; 0946-4778 ; 0172-6137
    DOI 10.1055/s-0043-1764160
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    In stock of ZB MED Cologne/Königswinter

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    ab Jg. 2022: Lesesaal (EG)

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  9. Article: The endogenous thrombin potential in patients with left ventricular assist device or heart transplant.

    Schlagenhauf, Axel / Haidl, Harald / Trummer, Georg / Berchtold-Herz, Michael / Pooth, Jan-Steffen / Strini, Tanja / Geisen, Ulrich / Beyersdorf, Friedhelm / Zieger, Barbara

    Frontiers in medicine

    2023  Volume 10, Page(s) 1155496

    Abstract: Background: The Heartmate 3 (HM 3) is a left ventricular assist device featuring less shear stress, milder acquired von Willebrand syndrome, and fewer bleeding incidences than its predecessor the Heartmate II (HM II). The novel surface coating of the HM ...

    Abstract Background: The Heartmate 3 (HM 3) is a left ventricular assist device featuring less shear stress, milder acquired von Willebrand syndrome, and fewer bleeding incidences than its predecessor the Heartmate II (HM II). The novel surface coating of the HM 3 suggests less contact activation of plasmatic coagulation. We hypothesized that patients with HM 3 exhibit fewer aberrations in their thrombin potential than patients with HM II. We compared these results with the thrombin potential of patients with heart transplantation (HTX).
    Methods: Thrombin generation in plasma samples of patients with HM II (
    Results: Three days postoperatively HM II patients exhibited a lower endogenous thrombin potential (ETP) than HM 3 and HTX patients (HM II: 947 ± 291 nM*min; HM 3: 1231 ± 176 nM*min; HTX: 1376 ± 162 nM*min,
    Conclusion: We observed a more aberrant thrombin generation in HM II than in HM 3 despite comparable anticoagulation and routine parameters. A trend toward lower values was still observable in HM 3 compared to HTX patients. Calibrated automated thrombography may be a good tool to monitor the coagulation state of these patients and guide anticoagulation in the future.
    Language English
    Publishing date 2023-04-12
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2775999-4
    ISSN 2296-858X
    ISSN 2296-858X
    DOI 10.3389/fmed.2023.1155496
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  10. Book ; Online ; Thesis: <dc:title>Einfluss des Pulsdrucks auf das Überleben von Patient*innen nach extrakorporaler kardiopulmonaler Reanimation (eCPR)</dc:title>

    Riefler, Antonia M. [Verfasser] / Wengenmayer, Tobias [Akademischer Betreuer] / Wengenmayer, Tobias [Sonstige] / Trummer, Georg [Sonstige]

    2023  

    Keywords Medizin, Gesundheit ; Medicine, Health
    Subject code sg610
    Language German
    Publisher Universität
    Publishing place Freiburg
    Document type Book ; Online ; Thesis
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