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  1. Article ; Online: Is representation enough or should we be targeting equitable inclusion?

    Gomez, Scarlett Lin / Tsai, Chiaojung Jillian

    Nature reviews. Clinical oncology

    2022  Volume 19, Issue 7, Page(s) 429–430

    MeSH term(s) Health Services Accessibility ; Humans
    Language English
    Publishing date 2022-04-09
    Publishing country England
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Comment
    ZDB-ID 2491410-1
    ISSN 1759-4782 ; 1759-4774
    ISSN (online) 1759-4782
    ISSN 1759-4774
    DOI 10.1038/s41571-022-00635-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 6029: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
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    ab Jg. 2022: Lesesaal (EG)
    Zs.MG 103: Show issues

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  2. Article: The International Response to the Coronavirus Disease (2019) COVID-19 Pandemic in Radiation Oncology.

    Wang, Edina / Tsai, Chiaojung Jillian / Miller, Robert C

    Advances in radiation oncology

    2020  Volume 5, Issue 4, Page(s) 523–524

    Keywords covid19
    Language English
    Publishing date 2020-06-29
    Publishing country United States
    Document type Editorial
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2020.06.015
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Safety and Tolerability of Metastasis-Directed Radiation Therapy in the Era of Evolving Systemic, Immune, and Targeted Therapies.

    Guimond, Elizabeth / Tsai, Chiaojung Jillian / Hosni, Ali / O'Kane, Grainne / Yang, Jonathan / Barry, Aisling

    Advances in radiation oncology

    2022  Volume 7, Issue 6, Page(s) 101022

    Abstract: Abstractpurpose: Systemic, immune, and target therapies are growing in use in the management of metastatic cancers. The aim of this review was to describe up-to-date published data on the safety and tolerability of metastasis-directed hypofractionated ... ...

    Abstract Abstractpurpose: Systemic, immune, and target therapies are growing in use in the management of metastatic cancers. The aim of this review was to describe up-to-date published data on the safety and tolerability of metastasis-directed hypofractionated radiation therapy (RT) when combined with newer systemic, immune, and targeted therapies and to provide suggested strategies to mitigate potential toxicities in the clinical setting.
    Methods and materials: A comprehensive search was performed for the time period between 1946 and August 2021 using predetermined keywords describing the use of noncentral nervous system palliative RT with commonly used targeted systemic therapies on PubMed and Medline databases. A total of 1022 articles were screened, and 130 met prespecified criteria to be included in this review.
    Results: BRAF and MEK inhibitors are reported to be toxic when given concurrently with RT; suspension 3 days and 1 to 2 days, respectively, prior and post-RT is suggested. Cetuximab, erlotinib/gefitinib, and osimertinib were generally safe to use concomitantly with conventional radiation. But in a palliative/hypofractionated RT setting, suspending cetuximab during radiation week, erlotinib/gefitinib 1 to 2 days, and osimertinib ≥2 days pre- and post-RT is suggested. Vascular endothelial growth factor inhibitors such as bevacizumab reported substantial toxicities, and the suggestion is to suspend 4 weeks before and after radiation. Less data exist on sorafenib and sunitinib; 5 to 10 days suspension before and after RT should be considered. As a precaution, until further data are available, for cyclin-dependent kinase 4-6 inhibitors, consideration of suspending treatment 1 to 2 days before and after RT should be given. Ipilimumab should be suspended 2 days before and after RT, and insufficient data exist for other immunotherapy agents. Trastuzumab and pertuzumab are generally safe to use in combination with RT, but insufficient data exist for other HER2 target therapy.
    Conclusions: Suggested approaches are described, using up-to-date literature, to aid clinicians in navigating the integration of newer targeted agents with hypofractionated palliative and/or ablative metastatic RT. Further prospective studies are required.
    Language English
    Publishing date 2022-07-14
    Publishing country United States
    Document type Journal Article ; Review
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2022.101022
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Big Data in Cancer Research: Real-World Resources for Precision Oncology to Improve Cancer Care Delivery.

    Tsai, Chiaojung Jillian / Riaz, Nadeem / Gomez, Scarlett Lin

    Seminars in radiation oncology

    2019  Volume 29, Issue 4, Page(s) 306–310

    Abstract: In oncology, the term "big data" broadly describes the rapid acquisition and generation of massive amounts of information, typically from population cancer registries, electronic health records, or large-scale genetic sequencing studies. The challenge of ...

    Abstract In oncology, the term "big data" broadly describes the rapid acquisition and generation of massive amounts of information, typically from population cancer registries, electronic health records, or large-scale genetic sequencing studies. The challenge of using big data in cancer research lies in interdisciplinary collaboration and information processing to unify diverse data sources and provide valid analytics to harness meaningful information. This article provides an overview of how big data approaches can be applied in cancer research, and how they can be used to translate information into new ways to ultimately make informed decisions that improve cancer care and delivery.
    MeSH term(s) Big Data ; Databases, Factual/statistics & numerical data ; Delivery of Health Care/methods ; Electronic Health Records/statistics & numerical data ; Humans ; Medical Oncology/methods ; Precision Medicine/methods ; Records/statistics & numerical data ; Registries/statistics & numerical data
    Language English
    Publishing date 2019-08-28
    Publishing country United States
    Document type Journal Article ; Research Support, N.I.H., Extramural ; Review
    ZDB-ID 1146999-7
    ISSN 1532-9461 ; 1053-4296
    ISSN (online) 1532-9461
    ISSN 1053-4296
    DOI 10.1016/j.semradonc.2019.05.002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.A 3654: Show issues Location:
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    bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
    Jg. 1995 - 2021: Lesesall (2.OG)
    ab Jg. 2022: Lesesaal (EG)

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  5. Article: The International Response to the Coronavirus Disease (2019) COVID-19 Pandemic in Radiation Oncology

    Wang, Edina / Tsai, Chiaojung Jillian / Miller, Robert C.

    Adv. Radiat. Oncol.

    Keywords covid19
    Publisher WHO
    Document type Article
    Note WHO #Covidence: #625524
    Database COVID19

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  6. Article ; Online: The International Response to the Coronavirus Disease (2019) COVID-19 Pandemic in Radiation Oncology

    Wang, Edina / Tsai, Chiaojung Jillian / Miller, Robert C.

    Advances in Radiation Oncology

    2020  Volume 5, Issue 4, Page(s) 523–524

    Keywords Oncology ; Radiology Nuclear Medicine and imaging ; covid19
    Language English
    Publisher Elsevier BV
    Publishing country us
    Document type Article ; Online
    ISSN 2452-1094
    DOI 10.1016/j.adro.2020.06.015
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

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  7. Article ; Online: Lymph Node Yield as Quality Metric for Clinically N0 Oral Cancer-Reply.

    Tsai, Chiaojung Jillian / Zheng, Junting / Zhang, Zhigang

    JAMA otolaryngology-- head & neck surgery

    2018  Volume 144, Issue 4, Page(s) 386–387

    MeSH term(s) Carcinoma, Squamous Cell ; Humans ; Lymph Nodes ; Mouth Neoplasms
    Language English
    Publishing date 2018-02-21
    Publishing country United States
    Document type Journal Article ; Comment
    ZDB-ID 2701825-8
    ISSN 2168-619X ; 2168-6181
    ISSN (online) 2168-619X
    ISSN 2168-6181
    DOI 10.1001/jamaoto.2017.3336
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Ul II Zs.87: Show issues Location:
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  8. Article ; Online: Palliative Care as a Component of High-Value and Cost-Saving Care During Hospitalization for Metastatic Cancer.

    Lu, Sifan / Rakovitch, Eileen / Hannon, Breffni / Zimmermann, Camilla / Dharmarajan, Kavita V / Yan, Michael / De Almeida, John R / Yao, Christopher M K L / Gillespie, Erin F / Chino, Fumiko / Yerramilli, Divya / Goonaratne, Ethan / Abdel-Rahman, Fadwa / Othman, Hiba / Mheid, Sara / Tsai, Chiaojung Jillian

    JCO oncology practice

    2024  , Page(s) OP2300576

    Abstract: Purpose: Randomized controlled trials have demonstrated that palliative care (PC) can improve quality of life and survival for outpatients with advanced cancer, but there are limited population-based data on the value of inpatient PC. We assessed PC as ... ...

    Abstract Purpose: Randomized controlled trials have demonstrated that palliative care (PC) can improve quality of life and survival for outpatients with advanced cancer, but there are limited population-based data on the value of inpatient PC. We assessed PC as a component of high-value care among a nationally representative sample of inpatients with metastatic cancer and identified hospitalization characteristics significantly associated with high costs.
    Methods: Hospitalizations of patients 18 years and older with a primary diagnosis of metastatic cancer from the National Inpatient Sample from 2010 to 2019 were analyzed. We used multivariable mixed-effects logistic regression to assess medical services, patient demographics, and hospital characteristics associated with higher charges billed to insurance and hospital costs. Generalized linear mixed-effects models were used to determine cost savings associated with provision of PC.
    Results: Among 397,691 hospitalizations from 2010 to 2019, the median charge per admission increased by 24.9%, from $44,904 in US dollars (USD) to $56,098 USD, whereas the median hospital cost remained stable at $14,300 USD. Receipt of inpatient PC was associated with significantly lower charges (odds ratio [OR], 0.62 [95% CI, 0.61 to 0.64];
    Conclusion: Inpatient PC is associated with reduced hospital costs for patients with metastatic cancer, irrespective of age and receipt of aggressive interventions. Integration of inpatient PC may de-escalate costs incurred through low-value inpatient interventions.
    Language English
    Publishing date 2024-03-05
    Publishing country United States
    Document type Journal Article
    ZDB-ID 3028198-2
    ISSN 2688-1535 ; 2688-1527
    ISSN (online) 2688-1535
    ISSN 2688-1527
    DOI 10.1200/OP.23.00576
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.A 7198: Show issues Location:
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  9. Article: Efforts to Reduce the Impact of Coronavirus Disease 2019 Outbreak on Radiation Oncology in Taiwan.

    Chen, Yi-Lun / Hsu, Feng-Ming / Tsai, Chiaojung Jillian / Cheng, Jason Chia-Hsien

    Advances in radiation oncology

    2020  Volume 5, Issue 4, Page(s) 534–537

    Keywords covid19
    Language English
    Publishing date 2020-04-06
    Publishing country United States
    Document type Journal Article
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2020.03.005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Impact of the Early COVID-19 Pandemic on Gender Participation in Academic Publishing in Radiation Oncology.

    Anabaraonye, Nancy / Tsai, Chiaojung Jillian / Saeed, Hina / Chino, Fumiko / Ekpo, Ekaete / Ahuja, Sudeep / Garcia, Oscar / Miller, Robert C

    Advances in radiation oncology

    2021  Volume 7, Issue 2, Page(s) 100845

    Abstract: Purpose: There is a known gender gap in oncology publishing with worse disparities within specialty fields such as radiation oncology. There has been a significant increase in the number of articles submitted to academic journals during the pandemic. ... ...

    Abstract Purpose: There is a known gender gap in oncology publishing with worse disparities within specialty fields such as radiation oncology. There has been a significant increase in the number of articles submitted to academic journals during the pandemic. Several analyses have suggested that the pandemic has had a disproportionate effect on academic productivity of women in academia, as measured by article publication rates.
    Materials and methods: The gender of first/co-first and corresponding/co-corresponding authors, as well as nonsenior versus senior status and manuscript type, for all articles published by
    Results: This examination of papers published during COVID-19 did not indicate a statistically significant decrease in the overall proportion of women publishing in
    Conclusions: During the early months of the COVID-19 pandemic, nonsenior female researchers participated less in article publishing in radiation oncology.
    Language English
    Publishing date 2021-11-18
    Publishing country United States
    Document type Journal Article
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2021.100845
    Database MEDical Literature Analysis and Retrieval System OnLINE

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