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  1. AU="Tseng L."
  2. AU="Guay, Joanne"
  3. AU="Paradise, Chris"
  4. AU="Hofmann, Nina"
  5. AU="Kaleagasi, Hakan"
  6. AU="Giulianelli, G"
  7. AU="Sanoj Punnen"

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  1. Artikel ; Online: Spinal anaesthesia with intravenous sedation for total hip arthroplasty in two patients with a history of orthotopic heart transplantation.

    Tseng, L / Al-Saidi, I / Channagiri, V

    Anaesthesia reports

    2023  Band 11, Heft 2, Seite(n) e12263

    Abstract: Many patients with orthotopic heart transplantation later undergo non-cardiac surgery. Historically, neuraxial anaesthesia has been avoided in these patients because the denervated heart is unable to compensate for hypotension via the baroreceptor reflex. ...

    Abstract Many patients with orthotopic heart transplantation later undergo non-cardiac surgery. Historically, neuraxial anaesthesia has been avoided in these patients because the denervated heart is unable to compensate for hypotension via the baroreceptor reflex. Here, we present the cases of two patients with prior heart transplantation who underwent total hip arthroplasty under spinal anaesthesia with intravenous sedation. In both cases, this technique was well-tolerated haemodynamically. We propose that spinal anaesthesia with intravenous sedation can be a safe and efficacious anaesthetic technique for selected patients with a history of orthotopic heart transplantation, with careful intraoperative fluid and pharmacological management.
    Sprache Englisch
    Erscheinungsdatum 2023-11-28
    Erscheinungsland England
    Dokumenttyp Case Reports
    ISSN 2637-3726
    ISSN (online) 2637-3726
    DOI 10.1002/anr3.12263
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  2. Artikel ; Online: Letter: Severe underweight and sarcopenia in decompensated cirrhosis are associated with high FGF21 levels-authors' reply.

    Alkhouri, Naim / Tseng, Leo / Balic, Kemal / Mansbach, Hank / Margalit, Maya

    Alimentary pharmacology & therapeutics

    2024  Band 59, Heft 6, Seite(n) 797–798

    Mesh-Begriff(e) Humans ; Sarcopenia/diagnosis ; Sarcopenia/complications ; Thinness/complications ; Liver Cirrhosis/complications ; Fibroblast Growth Factors
    Chemische Substanzen fibroblast growth factor 21 ; Fibroblast Growth Factors (62031-54-3)
    Sprache Englisch
    Erscheinungsdatum 2024-02-24
    Erscheinungsland England
    Dokumenttyp Letter
    ZDB-ID 639012-2
    ISSN 1365-2036 ; 0269-2813 ; 0953-0673
    ISSN (online) 1365-2036
    ISSN 0269-2813 ; 0953-0673
    DOI 10.1111/apt.17907
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  3. Buch ; Online: Byzantine Consensus in Abstract MAC Layer

    Tseng, Lewis / Sardina, Callie

    2023  

    Abstract: This paper studies the design of Byzantine consensus algorithms in an \textit{asynchronous }single-hop network equipped with the "abstract MAC layer" [DISC09], which captures core properties of modern wireless MAC protocols. Newport [PODC14], Newport and ...

    Abstract This paper studies the design of Byzantine consensus algorithms in an \textit{asynchronous }single-hop network equipped with the "abstract MAC layer" [DISC09], which captures core properties of modern wireless MAC protocols. Newport [PODC14], Newport and Robinson [DISC18], and Tseng and Zhang [PODC22] study crash-tolerant consensus in the model. In our setting, a Byzantine faulty node may behave arbitrarily, but it cannot break the guarantees provided by the underlying abstract MAC layer. To our knowledge, we are the first to study Byzantine faults in this model. We harness the power of the abstract MAC layer to develop a Byzantine approximate consensus algorithm and a Byzantine randomized binary consensus algorithm. Both of our algorithms require \textit{only} the knowledge of the upper bound on the number of faulty nodes $f$, and do \textit{not} require the knowledge of the number of nodes $n$. This demonstrates the "power" of the abstract MAC layer, as consensus algorithms in traditional message-passing models require the knowledge of \textit{both} $n$ and $f$. Additionally, we show that it is necessary to know $f$ in order to reach consensus. Hence, from this perspective, our algorithms require the minimal knowledge. The lack of knowledge of $n$ brings the challenge of identifying a quorum explicitly, which is a common technique in traditional message-passing algorithms. A key technical novelty of our algorithms is to identify "implicit quorums" which have the necessary information for reaching consensus. The quorums are implicit because nodes do not know the identity of the quorums -- such notion is only used in the analysis.

    Comment: Full version of our OPODIS 2023 paper
    Schlagwörter Computer Science - Distributed ; Parallel ; and Cluster Computing
    Thema/Rubrik (Code) 006
    Erscheinungsdatum 2023-11-06
    Erscheinungsland us
    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  4. Artikel: Choriocarcinoma Syndrome: A Rare Complication's Impact on Metastatic Germ Cell Tumor Outcomes.

    Herr, Sanjeev / Garabet, Razmig / Tseng, Lillian / Harzstark, Andrea L / Russin, Michael P

    Cureus

    2024  Band 16, Heft 4, Seite(n) e58388

    Abstract: Choriocarcinoma syndrome is a rare form of tumor lysis syndrome that predominantly occurs in patients with metastatic germ cell tumors, particularly those presenting with extensive lung metastases. We report a case of a previously healthy 37-year-old ... ...

    Abstract Choriocarcinoma syndrome is a rare form of tumor lysis syndrome that predominantly occurs in patients with metastatic germ cell tumors, particularly those presenting with extensive lung metastases. We report a case of a previously healthy 37-year-old male who presented with a painless left-sided neck lump and nipples with an increased sensitivity to light touch. Workup revealed a significantly elevated beta-human chorionic gonadotropin, a testicular mass, and innumerable pulmonary metastases, suggesting metastatic non-seminomatous germ cell tumor. Following the initiation of chemotherapy with etoposide, ifosfamide, and cisplatin (VIP), the patient experienced a rapid decline in respiratory function, culminating in acute respiratory distress syndrome and subsequent death from respiratory failure six weeks after starting treatment. This case emphasizes the importance of early detection and intervention in managing non-seminomatous germ cell tumors and highlights the critical need for awareness of choriocarcinoma syndrome's risks, the challenges of treatment delays for fertility preservation, and the exploration of alternative therapeutic strategies to improve outcomes in this high-risk patient population.
    Sprache Englisch
    Erscheinungsdatum 2024-04-16
    Erscheinungsland United States
    Dokumenttyp Case Reports
    ZDB-ID 2747273-5
    ISSN 2168-8184
    ISSN 2168-8184
    DOI 10.7759/cureus.58388
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  5. Buch ; Online: Distributed Multi-writer Multi-reader Atomic Register with Optimistically Fast Read and Write

    Tseng, Lewis / Zhou, Neo / Dumas, Cole / Bantikyan, Tigran / Palmieri, Roberto

    2023  

    Abstract: A distributed multi-writer multi-reader (MWMR) atomic register is an important primitive that enables a wide range of distributed algorithms. Hence, improving its performance can have large-scale consequences. Since the seminal work of ABD emulation in ... ...

    Abstract A distributed multi-writer multi-reader (MWMR) atomic register is an important primitive that enables a wide range of distributed algorithms. Hence, improving its performance can have large-scale consequences. Since the seminal work of ABD emulation in the message-passing networks [JACM '95], many researchers study fast implementations of atomic registers under various conditions. "Fast" means that a read or a write can be completed with 1 round-trip time (RTT), by contacting a simple majority. In this work, we explore an atomic register with optimal resilience and "optimistically fast" read and write operations. That is, both operations can be fast if there is no concurrent write. This paper has three contributions: (i) We present Gus, the emulation of an MWMR atomic register with optimal resilience and optimistically fast reads and writes when there are up to 5 nodes; (ii) We show that when there are > 5 nodes, it is impossible to emulate an MWMR atomic register with both properties; and (iii) We implement Gus in the framework of EPaxos and Gryff, and show that Gus provides lower tail latency than state-of-the-art systems such as EPaxos, Gryff, Giza, and Tempo under various workloads in the context of geo-replicated object storage systems.
    Schlagwörter Computer Science - Distributed ; Parallel ; and Cluster Computing
    Thema/Rubrik (Code) 006
    Erscheinungsdatum 2023-04-18
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    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  6. Buch ; Online: Impact of the Consistency Model on Checkpointing of Distributed Shared Memory

    Kulkarni, Sandeep / Nguyen, Duong / Tseng, Lewis / Vaidya, Nitin

    2022  

    Abstract: In this report, we consider the impact of the consistency model on checkpointing and rollback algorithms for distributed shared memory. In particular, we consider specific implementations of four consistency models for distributed shared memory, namely, ... ...

    Abstract In this report, we consider the impact of the consistency model on checkpointing and rollback algorithms for distributed shared memory. In particular, we consider specific implementations of four consistency models for distributed shared memory, namely, linearizability, sequential consistency, causal consistency and eventual consistency, and develop checkpointing and rollback algorithms that can be integrated into the implementations of the consistency models. Our results empirically demonstrate that the mechanisms used to implement stronger consistency models lead to simpler or more efficient checkpointing algorithms.
    Schlagwörter Computer Science - Distributed ; Parallel ; and Cluster Computing
    Erscheinungsdatum 2022-08-03
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    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  7. Buch ; Online: Technical Report

    Nelson-Slivon, Jacob / Tseng, Lewis / Palmieri, Roberto

    Asymmetric Mutual Exclusion for RDMA

    2022  

    Abstract: Coordinating concurrent access to a shared resource using mutual exclusion is a fundamental problem in computation. In this paper, we present a novel approach to mutual exclusion designed specifically for distributed systems leveraging a popular network ... ...

    Abstract Coordinating concurrent access to a shared resource using mutual exclusion is a fundamental problem in computation. In this paper, we present a novel approach to mutual exclusion designed specifically for distributed systems leveraging a popular network communication technology, remote direct memory access (RDMA). Our approach enables local processes to avoid using RDMA operations entirely, limits the number of RDMA operations required by remote processes, and guarantees both starvation-freedom and fairness.
    Schlagwörter Computer Science - Distributed ; Parallel ; and Cluster Computing
    Erscheinungsdatum 2022-08-19
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    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  8. Buch ; Online: Echo-CGC

    Zhang, Qinzi / Tseng, Lewis

    A Communication-Efficient Byzantine-tolerant Distributed Machine Learning Algorithm in Single-Hop Radio Network

    2020  

    Abstract: In this paper, we focus on a popular DML framework -- the parameter server computation paradigm and iterative learning algorithms that proceed in rounds. We aim to reduce the communication complexity of Byzantine-tolerant DML algorithms in the single-hop ...

    Abstract In this paper, we focus on a popular DML framework -- the parameter server computation paradigm and iterative learning algorithms that proceed in rounds. We aim to reduce the communication complexity of Byzantine-tolerant DML algorithms in the single-hop radio network. Inspired by the CGC filter developed by Gupta and Vaidya, PODC 2020, we propose a gradient descent-based algorithm, Echo-CGC. Our main novelty is a mechanism to utilize the broadcast properties of the radio network to avoid transmitting the raw gradients (full $d$-dimensional vectors). In the radio network, each worker is able to overhear previous gradients that were transmitted to the parameter server. Roughly speaking, in Echo-CGC, if a worker "agrees" with a combination of prior gradients, it will broadcast the "echo message" instead of the its raw local gradient. The echo message contains a vector of coefficients (of size at most $n$) and the ratio of the magnitude between two gradients (a float). In comparison, the traditional approaches need to send $n$ local gradients in each round, where each gradient is typically a vector in an ultra-high dimensional space ($d\gg n$). The improvement on communication complexity of our algorithm depends on multiple factors, including number of nodes, number of faulty workers in an execution, and the cost function. We numerically analyze the improvement, and show that with a large number of nodes, Echo-CGC reduces $80\%$ of the communication under standard assumptions.
    Schlagwörter Computer Science - Distributed ; Parallel ; and Cluster Computing ; Computer Science - Machine Learning ; Computer Science - Networking and Internet Architecture
    Thema/Rubrik (Code) 000
    Erscheinungsdatum 2020-11-14
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    Dokumenttyp Buch ; Online
    Datenquelle BASE - Bielefeld Academic Search Engine (Lebenswissenschaftliche Auswahl)

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  9. Artikel ; Online: Primary care family physicians' experiences with clinical integration in qualitative and mixed reviews: a systematic review protocol.

    Tseng, L Olivia / Newton, Christie / Hall, David / Lee, Esther J / Chang, Howard / Poureslami, Iraj / Vasarhelyi, Krisztina / Lacaille, Diane / Mitton, Craig

    BMJ open

    2023  Band 13, Heft 7, Seite(n) e067576

    Abstract: Introduction: Clinical (service) integration in primary care settings describes how comprehensive care is coordinated by family physicians (FPs) over time across healthcare contexts to meet patient care needs. To improve care integration and healthcare ... ...

    Abstract Introduction: Clinical (service) integration in primary care settings describes how comprehensive care is coordinated by family physicians (FPs) over time across healthcare contexts to meet patient care needs. To improve care integration and healthcare service planning, a systematic approach to understanding its numerous influencing factors is paramount. The objective of this study is to generate a comprehensive map of FP-perceived factors influencing clinical integration across diseases and patient demographics.
    Methods and analysis: We developed the protocol with the guidance of the Joanna Briggs Institute systematic review methodology framework. An information specialist built search strategies for MEDLINE, EMBASE and CINAHL databases using keywords and MeSH terms iteratively collected from a multidisciplinary team. Two reviewers will work independently throughout the study process, from article selection to data analysis. The identified records will be screened by title and abstract and reviewed in the full text against the criteria: FP in primary care (population), clinical integration (concept) and qualitative and mixed reviews published in 2011-2021 (context). We will first describe the characteristics of the review studies. Then, we will extract qualitative, FP-perceived factors and group them by content similarities, such as patient factors. Lastly, we will describe the types of extracted factors using a custom framework.
    Ethics and dissemination: Ethics approval is not required for a systematic review. The identified factors will help generate an item bank for a survey that will be developed in the Phase II study to ascertain high-impact factors for intervention(s), as well as evidence gaps to guide future research. We will share the study findings with various knowledge users to promote awareness of clinical integration issues through multiple channels: publications and conferences for researchers and care providers, an executive summary for clinical leaders and policy-makers, and social media for the public.
    Mesh-Begriff(e) Humans ; Academies and Institutes ; Administrative Personnel ; Clinical Trials, Phase II as Topic ; Comprehensive Health Care ; Physicians, Family ; Primary Health Care ; Systematic Reviews as Topic
    Sprache Englisch
    Erscheinungsdatum 2023-07-11
    Erscheinungsland England
    Dokumenttyp Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2599832-8
    ISSN 2044-6055 ; 2044-6055
    ISSN (online) 2044-6055
    ISSN 2044-6055
    DOI 10.1136/bmjopen-2022-067576
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  10. Artikel: Systemic Effects of Perineural Glucocorticoids on Fasting Serum Glucose, Potassium, and White Blood Cell Count in Total Hip Arthroplasty.

    Sharma, Avijit / Dai, Feng / Tseng, Lanya / Effraim, Philip R / Zhou, Bin / Schonberger, Robert B / Li, Jinlei

    Journal of pain research

    2023  Band 16, Seite(n) 553–561

    Abstract: Purpose: Glucocorticoids are commonly used as regional anesthesia adjuvants to improve blockade quality and duration. There are limited data in the literature regarding the potential systemic effects and safety of perineural glucocorticoids. This study ... ...

    Abstract Purpose: Glucocorticoids are commonly used as regional anesthesia adjuvants to improve blockade quality and duration. There are limited data in the literature regarding the potential systemic effects and safety of perineural glucocorticoids. This study examines the effects of perineural glucocorticoids on serum glucose, potassium, and white blood cell count (WBC) in the immediate postoperative period after primary total hip arthroplasty (THA).
    Patients and methods: A retrospective cohort study was carried out at a tertiary academic medical center utilizing electronic health records of 210 patients who underwent THA, for which patients received either a periarticular local anesthetic injection alone (PAI, N=132) or additional peripheral nerve blocks (PNB, N=78) containing 10 mg dexamethasone and 80 mg methylprednisolone acetate (PAI+PNB). The primary outcome was change in serum glucose from a preoperative baseline on postoperative days (POD) 1, 2, and 3. Secondary outcomes included changes in WBC and serum potassium.
    Results: The change in serum glucose from baseline was found to be significantly higher in the PAI+PNB group compared to the PAI group on POD 1 (mean difference 19.87 mg/dL, 95% CI [12.42, 27.32];
    Conclusion: Patients who underwent THA and received PAI+PNB with glucocorticoid adjuvants demonstrated higher elevations in serum glucose for the first two PODs compared to patients who received PAI alone. These differences resolved by a third POD and are likely to be of no clinical significance.
    Sprache Englisch
    Erscheinungsdatum 2023-02-18
    Erscheinungsland New Zealand
    Dokumenttyp Journal Article
    ZDB-ID 2495284-9
    ISSN 1178-7090
    ISSN 1178-7090
    DOI 10.2147/JPR.S395336
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