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  1. Article ; Online: Editorial: From simulation to the operating theatre: new insights in translational surgery.

    Balak, Naci / Tsianaka, Eleni / Zoia, Cesare / Sekhar, Amitendu / Ganau, Mario

    Frontiers in medical technology

    2023  Volume 5, Page(s) 1282248

    Language English
    Publishing date 2023-09-21
    Publishing country Switzerland
    Document type Editorial
    ISSN 2673-3129
    ISSN (online) 2673-3129
    DOI 10.3389/fmedt.2023.1282248
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Direct Consequences of Cranioplasty to the Brain: Intracranial Pressure Study.

    Tsianaka, Eleni / Singh, Ajit / Drosos, Evangelos / Fountas, Kostas

    The Journal of craniofacial surgery

    2021  Volume 32, Issue 8, Page(s) 2779–2783

    Abstract: Abstract: Intracranial pressure (ICP) is a crucial factor that we need to take into account in all major pathophysiological changes of the brain after decompressive craniectomy (DC) and cranioplasty (CP). The purpose of our study was to check ICP values ...

    Abstract Abstract: Intracranial pressure (ICP) is a crucial factor that we need to take into account in all major pathophysiological changes of the brain after decompressive craniectomy (DC) and cranioplasty (CP). The purpose of our study was to check ICP values before and after cranioplasty and its relation to various parameters (imaging, demographics, time of cranioplasty, and type of graft) as well as its possible relation to postsurgical complications. The authors performed a prospective study in which they selected as participants adults who had undergone unilateral frontotemporoparietal DC and were planned to have cranioplasty. Intracranial pressure was measured with optical fiber sensor in the epidural space and did not affect cranioplasty in any way.Twenty-five patients met the criteria. The mean vcICP (value change of ICP) was 1.2 mm Hg, the mean ΔICP (absolute value change of the ICP) was 2.24 mm Hg and in the majority of cases there was an increase in ICP. The authors found 3 statistically significant correlations: between gender and ΔICP, Δtime (time between DC and CP) and vcICP, and pre-ICP and ±ICP (quantitative change of the ICP).Μale patients tend to develop larger changes of ICP values during CP. As the time between the 2 procedures (DC and CP) gets longer, the vcICP is decreased. However, after certain time it shows a tendency to remain around zero. Lower pre-ICP values (close to or below zero) are more possible to increase after bone flap placement. It seems that the brain tends to restore its pre-DC conditions after CP by taking near-to-normal ICP values.
    MeSH term(s) Adult ; Brain/diagnostic imaging ; Brain/surgery ; Brain Injuries, Traumatic/surgery ; Decompressive Craniectomy ; Humans ; Intracranial Pressure ; Postoperative Complications ; Prospective Studies ; Retrospective Studies
    Language English
    Publishing date 2021-11-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000007945
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Some Interesting Points of Competition of X-Ray using during the Greco-Ottoman War in 1897 and Development of Neurosurgical Radiology: A Reminiscence.

    Kanat, Ayhan / Tsianaka, Eleni / Gasenzer, Elena Romana / Drosos, Evangelos

    Turkish neurosurgery

    2021  Volume 32, Issue 5, Page(s) 877–881

    Abstract: Aim: To investigate the competition of radiologic development between Turkey and Greece during the Greco-Ottoman War when the first application of X-Ray took place.: Material and methods: A literature review was conducted, and we searched the ... ...

    Abstract Aim: To investigate the competition of radiologic development between Turkey and Greece during the Greco-Ottoman War when the first application of X-Ray took place.
    Material and methods: A literature review was conducted, and we searched the published papers about X-Ray using during the Greco-Turkish War in 1897.
    Results: The use of X-Rays in the military dates to the Greco-Ottoman War in 1897, which is an important issue because X-ray was first specifically used in this war. The radiographic images were used to show the evidence of pieces of bullets and shrapnel inside the bodies of soldiers.
    Conclusion: The experience of the Ottoman Empire and Greece is important for the development of neurosurgical radiology. Both Greek and Turkish parts used the X-Ray technology before any of the risks and adverse effects were unknown. More studies are required.
    MeSH term(s) Ottoman Empire ; Radiology ; Turkey ; X-Rays
    Language English
    Publishing date 2021-12-02
    Publishing country Turkey
    Document type Journal Article ; Review
    ZDB-ID 1203779-5
    ISSN 1019-5149
    ISSN 1019-5149
    DOI 10.5137/1019-5149.JTN.33484-20.3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Post-Cranioplasty Complications: Lessons From a Prospective Study Assessing Risk Factors.

    Tsianaka, Eleni / Drosos, Evangelos / Singh, Ajit / Tasiou, Anastasia / Gatos, Charalabos / Fountas, Kostas

    The Journal of craniofacial surgery

    2021  Volume 32, Issue 2, Page(s) 530–534

    Abstract: Abstract: Complication rate related with cranioplasty is described as very high in most of relevant studies. The aim of our study was to try to identify possible factors, that could predict complications following cranioplasty. The authors hypothesized ... ...

    Abstract Abstract: Complication rate related with cranioplasty is described as very high in most of relevant studies. The aim of our study was to try to identify possible factors, that could predict complications following cranioplasty. The authors hypothesized that some physical characteristics on the preoperative brain computed tomography (CT) scan can be predictive for complications.The authors carried out a prospective observational study. All patients were adults after decompressive craniectomy, planned for cranioplasty and had a brain CT scan the day before cranioplasty. Our data pool included demographics, reason of craniectomy, various radiological parameters, the time of cranioplasty after craniectomy, the type of cranioplasty bone flap, and the complications.Twenty-five patients were included in the study. The authors identified statistically significant correlation between time of cranioplasty after craniectomy and the complications, as well as between the type of cranioplasty implant and the complications. There was statistically significant correlation between complications and the distance of the free brain surface from the level of the largest skull defect dimension - free brain surface deformity (FBSD). Moreover, the correlation between FBSD and the time of cranioplasty was statistically significant.It seems that for adult patients with unilateral DC the shorter time interval between craniectomy and cranioplasty lowers the risk for complications. The risk seems to be decreased further, by using autologous bone flap. Low values of the FBSD increase the risk for complications. This risk factor can be avoided, by shortening the time between craniectomy and cranioplasty.
    MeSH term(s) Adult ; Decompressive Craniectomy ; Humans ; Postoperative Complications/epidemiology ; Postoperative Complications/surgery ; Prospective Studies ; Reconstructive Surgical Procedures ; Retrospective Studies ; Risk Factors ; Skull/diagnostic imaging ; Skull/surgery
    Language English
    Publishing date 2021-03-11
    Publishing country United States
    Document type Journal Article ; Observational Study
    ZDB-ID 1159501-2
    ISSN 1536-3732 ; 1049-2275
    ISSN (online) 1536-3732
    ISSN 1049-2275
    DOI 10.1097/SCS.0000000000007344
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: European Medical Students' Views on Neurosurgery, with Emphasis on South-East Europe (Albania, Greece, Serbia, and Turkey).

    Esen Aydin, Aysegul / Gazioglu, Nurperi / Tasiou, Anastasia / Mihaylova, Stiliana / Salokorpi, Niina / Karampouga, Maria / Broekman, Marike L D / Janssen, Insa K / Magnadottir, Hulda B / Somma, Teresa / Pajaj, Ermira / Hernandez Duran, Silvia / Vayssiere, Pia / Rodríguez-Hernández, Ana / Lambrianou, Xanthoula / Tsianaka, Eleni / Rosseau, Gail / Murphy, Mary

    World neurosurgery

    2024  Volume 185, Page(s) e523–e531

    Abstract: Background: Neurosurgery, an intricate and dynamic surgical specialty, faces challenges in attracting medical graduates. Despite its potential appeal, a decreasing trend in medical students opting for surgical specialties, including neurosurgery, is ... ...

    Abstract Background: Neurosurgery, an intricate and dynamic surgical specialty, faces challenges in attracting medical graduates. Despite its potential appeal, a decreasing trend in medical students opting for surgical specialties, including neurosurgery, is noted. This study aims to assess European medical students' perceptions of neurosurgery, focusing on South-East Europe, and address concerns about the declining interest in this field.
    Methods: A comprehensive digital survey, comprising 33 questions, was distributed to 1115 medical students across 17 European countries. The survey, conducted over 9 months, gathered responses through European neurosurgical societies, the European Association of Neurosurgical Societies (EANS), and university channels. Statistical analysis utilized IBM Statistical Package for the Social Sciences, presenting data through counts, proportions, and χ
    Results: The study reveals that, over the survey period, 834 medical students completed the questionnaire, with a predominant representation from South-East Europe. While 43.2% of participants were considering a surgical career, neurosurgery emerged as the most preferred specialty (26.37%). Despite this interest, 80.2% reported insufficient knowledge about pursuing a neurosurgical career, with limited exposure during medical education. Concerns about work-life balance, heavy workload, and hierarchical structures were prominent among respondents.
    Conclusions: The findings underscore the need for targeted interventions to address concerns influencing medical students' decisions regarding neurosurgery. Improving neurosurgical education, dispelling misconceptions, and creating a supportive work environment are crucial steps to attract and retain diverse talented individuals in neurosurgery. These efforts will be vital in narrowing the gap between the demand for neurosurgeons and the number of medical graduates entering the field, ensuring a sustainable future for this essential surgical specialty.
    MeSH term(s) Students, Medical/psychology ; Students, Medical/statistics & numerical data ; Humans ; Neurosurgery/education ; Career Choice ; Male ; Female ; Surveys and Questionnaires ; Europe ; Adult ; Greece ; Young Adult ; Serbia ; Turkey ; Attitude of Health Personnel
    Language English
    Publishing date 2024-02-19
    Publishing country United States
    Document type Journal Article
    ZDB-ID 2534351-8
    ISSN 1878-8769 ; 1878-8750
    ISSN (online) 1878-8769
    ISSN 1878-8750
    DOI 10.1016/j.wneu.2024.02.065
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Clipping versus coiling in posterior circulation intracranial aneurysms: a meta-analysis.

    Tsianaka, Eleni / Al-Shawish, Abdullah / Potapov, Alexander / Fountas, Kostas / Spyrou, Michael / Konovalov, Nikolay

    Chinese neurosurgical journal

    2019  Volume 5, Page(s) 16

    Abstract: Background: Posterior circulation intracranial aneurysm (IA) treatment remains challenging, due to the anatomy of the area and the high rupture possibility. Endovascular treatment seems to be more suitable for these aneurysms, but studies focused on ... ...

    Abstract Background: Posterior circulation intracranial aneurysm (IA) treatment remains challenging, due to the anatomy of the area and the high rupture possibility. Endovascular treatment seems to be more suitable for these aneurysms, but studies focused on endovascular treatment demonstrate a high rate of re-intervention needing. A meta-analysis might offer a clearer view, being useful in a more effective treatment planning.
    Methods: A systematic search was performed, using the PubMed database platform. The final article pool contained 20 articles. Studied parameters were operative mortality, late mortality, permanent neurologic deficit (PND), and the need for re-intervention (Re-int). We divided patients into two subgroups, those with ruptured and those with unruptured aneurysm. Statistical analysis was performed using appropriate software.
    Results: In the total population (645 patients), there was a superiority of coiling over clipping in terms of PND and of coiling in terms of Re-int. As regards mortality, there was no clear superiority of one method over the other.
    Conclusions: The current study came to the conclusion that there is a superiority of coiling over clipping in terms of PND. On the other hand, clipping seems to be superior to coiling in terms of the need for re-intervention. As regards mortality (both operative and late), there is no clear superiority of one method over the other. Studying subgroups of patients (ruptured and unruptured posterior circulation IAs), in terms of PND, there is no superiority of one method over the other. The same goes for Op-Mo on ruptured aneurysms.
    Language English
    Publishing date 2019-06-19
    Publishing country England
    Document type Journal Article
    ISSN 2095-9370
    ISSN 2095-9370
    DOI 10.1186/s41016-019-0163-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article ; Online: Neurosurgeons and the fight with COVID-19: a position statement from the EANS Individual Membership Committee.

    Ganau, Mario / Netuka, David / Broekman, Marike / Zoia, Cesare / Tsianaka, Eleni / Schwake, Michael / Balak, Naci / Sekhar, Amitendu / Ridwan, Sami / Clusmann, Hans

    Acta neurochirurgica

    2020  Volume 162, Issue 8, Page(s) 1777–1782

    MeSH term(s) Access to Information ; Betacoronavirus ; COVID-19 ; Communication ; Coronavirus Infections/epidemiology ; Europe/epidemiology ; Humans ; Neurosurgeons ; Neurosurgery ; Pandemics ; Personal Protective Equipment ; Pneumonia, Viral/epidemiology ; SARS-CoV-2 ; Societies, Medical ; Stress, Psychological
    Keywords covid19
    Language English
    Publishing date 2020-05-29
    Publishing country Austria
    Document type Editorial
    ZDB-ID 80010-7
    ISSN 0942-0940 ; 0001-6268
    ISSN (online) 0942-0940
    ISSN 0001-6268
    DOI 10.1007/s00701-020-04360-3
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  8. Article: According to which factors in severe traumatic brain injury craniectomy could be beneficial.

    Fotakopoulos, George / Tsianaka, Eleni / Vagkopoulos, Konstantinos / Fountas, Kostas N

    Surgical neurology international

    2016  Volume 7, Page(s) 19

    Abstract: Background: To investigate the clinical outcome at 101 patients undergoing decompressive craniectomy (DC) after severe traumatic brain injury (TBI).: Methods: Age, Glasgow Coma Scale (GCS) at the time of intubation, and the intraoperative ... ...

    Abstract Background: To investigate the clinical outcome at 101 patients undergoing decompressive craniectomy (DC) after severe traumatic brain injury (TBI).
    Methods: Age, Glasgow Coma Scale (GCS) at the time of intubation, and the intraoperative intracranial pressure (ICP) were recorded. Formal DC was performed in all cases and the square surface of bone flap was calculated in cm(2) based on the length and the width from computed tomography scan.
    Results: The difference of good neurological recovery (Glasgow outcome score 4-5), between patients with ICP ≤20 mmHg, GCS ≥5, age ≤60 years, and bone flap ≥130 cm(2) and those with ICP >20 mmHg, GCS <5, age >60 years, and bone flap <130 cm(2), was statistically significant.
    Conclusion: Although the application of DC in severe TBI is controversial and the population in this study is small, our study demonstrates the threshold of the specific factors (patient age, ICP and GCS on the day of the surgery and the size of the bone flap) which may help in the decision of performing DC. Furthermore, this study proves that the different combinations and mainly at the same time involvement of all prognostic parameters (age <60, GCS <5, bone flap ≥130 cm(2), and ICP ≤20 at time of DC surgery) allow a better outcome.
    Language English
    Publishing date 2016-02-17
    Publishing country United States
    Document type Journal Article
    ISSN 2229-5097
    ISSN 2229-5097
    DOI 10.4103/2152-7806.176671
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  9. Article ; Online: Posttraumatic Hydrocephalus after Decompressive Craniectomy in 126 Patients with Severe Traumatic Brain Injury.

    Fotakopoulos, George / Tsianaka, Eleni / Siasios, Giannis / Vagkopoulos, Konstantinos / Fountas, Kostas

    Journal of neurological surgery. Part A, Central European neurosurgery

    2016  Volume 77, Issue 2, Page(s) 88–92

    Abstract: Objective: Severe traumatic brain injuries (TBIs) occur frequently. In some of these patients decompressive craniectomy (DC) must be performed. Posttraumatic hydrocephalus (PTH) can develop after TBI further damaging the brain. DC is considered to be ... ...

    Abstract Objective: Severe traumatic brain injuries (TBIs) occur frequently. In some of these patients decompressive craniectomy (DC) must be performed. Posttraumatic hydrocephalus (PTH) can develop after TBI further damaging the brain. DC is considered to be one of the causes of PTH. This study defines the incidence of PTH in TBI patients who underwent DC and tries to determine associated factors.
    Materials and methods: We conducted a retrospective study (2009-2013) that included 126 patients with severe TBI and DC. The collected data were demographics, the craniectomy size, the presence or absence of hydrocephalus, the need for changing the opening pressure of the valve of the cerebrospinal fluid (CSF) shunt or replacing all or parts of the CSF shunt, and the interval between cranioplasty and shunt placement. We excluded patients with additional intraventricular hemorrhage and those with bilateral or bifrontal DC.
    Results: Ten of the 126 patients (7.9%) developed PTH and were treated with a CSF shunt. There was no statistical correlation between development of PTH and age or sex, but a statistically significant correlation between development of PTH and the size of DC.
    Conclusion: Our study suggests that PTH development is multifactorial and shows that PTH is not that rare. We showed a correlation between craniectomy size and the incidence of PTH.
    MeSH term(s) Adolescent ; Adult ; Aged ; Brain Injuries, Traumatic/surgery ; Decompressive Craniectomy/adverse effects ; Female ; Humans ; Hydrocephalus/epidemiology ; Hydrocephalus/etiology ; Incidence ; Male ; Postoperative Complications/epidemiology ; Retrospective Studies ; Young Adult
    Language English
    Publishing date 2016-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2651663-9
    ISSN 2193-6323 ; 2193-6315
    ISSN (online) 2193-6323
    ISSN 2193-6315
    DOI 10.1055/s-0035-1558411
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  10. Article: Could IGF-I levels play a neuroprotective role in patients with large vestibular schwannomas?

    Fotakopoulos, George / Fountas, Kostas / Tsianaka, Eleni / Kotlia, Polikceni / Pachatouridis, Dimitrios / Paschalis, Thanos / Voulgaris, Spyridon

    Future science OA

    2017  Volume 4, Issue 2, Page(s) FSO260

    Abstract: Aim: To evaluate the possible superiority of outcome in patients with elevated IGF-I levels after vestibular schwannoma (VS) resection.: Patients & methods: This retrospective study included 65 patients (34 male, 52.3%) with VS operated in between ... ...

    Abstract Aim: To evaluate the possible superiority of outcome in patients with elevated IGF-I levels after vestibular schwannoma (VS) resection.
    Patients & methods: This retrospective study included 65 patients (34 male, 52.3%) with VS operated in between January 2009 and April 2014 (follow-up 3.2 ± 0.7 years). Preoperative or postoperative IGF-I levels were identified for each patient.
    Results: Patients were divided into two groups: Group A (small size tumor), 56 patients; and Group B (large size tumor), 9 cases. IGF-I levels in Group A (195.8 ± 32.9 ng/ml) were compared with those of Group B (242.2 ± 22.2 ng/ml) and were found to have statistically significant difference (p = 0.001).
    Conclusion: Increased IGF-I levels could hold a key role in nerve recovery in patients undergoing surgical resection of large VS.
    Language English
    Publishing date 2017-11-10
    Publishing country England
    Document type Journal Article
    ISSN 2056-5623
    ISSN 2056-5623
    DOI 10.4155/fsoa-2017-0103
    Database MEDical Literature Analysis and Retrieval System OnLINE

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