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  1. Article: [Surgical Treatment with Pulsed Lavage Irrigation for Infective Endocarditis].

    Tsujimoto, Kotone / Yoshida, Hideo / Muraoka, Genya / Kuinose, Masahiko

    Kyobu geka. The Japanese journal of thoracic surgery

    2024  Volume 77, Issue 2, Page(s) 106–109

    Abstract: Introduction: Pulsed lavage irrigation (PLI) is a procedure used to wash contaminated soft tissues and prevent infection in orthopedic surgery. We applicated PLI for surgical treatment of infective endocarditis( IE).: Subjects and methods: From ... ...

    Abstract Introduction: Pulsed lavage irrigation (PLI) is a procedure used to wash contaminated soft tissues and prevent infection in orthopedic surgery. We applicated PLI for surgical treatment of infective endocarditis( IE).
    Subjects and methods: From January 2017 to June 2021, 6 cases underwent surgical treatment IE using PLI. We investigated an efficacy of PLI.
    Results: Infected valves were mitral valve in 4 cases, aortic valve in 1 case, and aortic prosthetic valve in 1 case. The performed procedures were mitral valve plasty in 4 cases, aortic valve replacement in 1 case, and 1 removal of vegetation on the aortic prosthetic valve. No recurrence of IE or no deterioration of the native valve or the prosthetic valve was observed in follow-up periods.
    Conclusion: PLI was useful for surgical treatment of IE because of no recurrence of IE or no deterioration of native mitral valves or the aortic prosthetic valve.
    MeSH term(s) Humans ; Therapeutic Irrigation/adverse effects ; Endocarditis, Bacterial/surgery ; Endocarditis, Bacterial/complications ; Endocarditis/surgery ; Mitral Valve/surgery ; Aortic Valve/surgery ; Heart Valve Prosthesis/adverse effects
    Language Japanese
    Publishing date 2024-03-11
    Publishing country Japan
    Document type English Abstract ; Journal Article
    ZDB-ID 603899-2
    ISSN 0021-5252
    ISSN 0021-5252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Diabetic ketoacidosis and sinus arrest conditions in a patient with an inserted cardiac pacemaker.

    Anno, Takatoshi / Tsujimoto, Kotone / Shigemoto, Ryo / Kojima, Sunao / Kaneto, Hideaki

    Acta diabetologica

    2021  Volume 58, Issue 5, Page(s) 657–660

    Language English
    Publishing date 2021-01-03
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 1097676-0
    ISSN 1432-5233 ; 0940-5429
    ISSN (online) 1432-5233
    ISSN 0940-5429
    DOI 10.1007/s00592-020-01615-4
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: [Endoventricular Stepwise Plication for Left Ventricular Aneurysm].

    Tokunaga, Noriyuki / Watanabe, Tatsuya / Kondo, Kensuke / Tsujimoto, Kotone / Yoshida, Hideo / Kuinose, Masahiko

    Kyobu geka. The Japanese journal of thoracic surgery

    2021  Volume 74, Issue 2, Page(s) 103–107

    Abstract: A 69-year-old man was treated with oral anticoagulation for the left ventricular (LV) aneurysm. Echocardiography revealed dyskinetic apex with a mobile thrombus. The estimated LV end-diastolic and end-systolic volume index (LVEDVI, LVESVI) was 76 and 44 ... ...

    Abstract A 69-year-old man was treated with oral anticoagulation for the left ventricular (LV) aneurysm. Echocardiography revealed dyskinetic apex with a mobile thrombus. The estimated LV end-diastolic and end-systolic volume index (LVEDVI, LVESVI) was 76 and 44 ml/m2, respectively. After the LV was opened at the apex parallel to the left anterior descending artery, removal of LV thrombus was performed. LV volume was 70 ml, and diameter of LV aneurysm was 3 cm. After setting a neo-apex, the boundary between the normal and aneurysmal scar tissue were doubly encircled by a pledgeted 2-0 polypropylene suture, and preserved the same diameter as the "aneurysmal neck" (3 cm) in order to secure the minimal residual LV volume. Similarly, second and third circular stitches were placed toward the neo-apex to make the ventricle into an elliptical shape. A postoperative echocardiography showed a well-reconstructed physiologic shape, LV volume( LVEDVI 62 ml/m2, LVESVI 27 ml/m2), and improved LV function.
    MeSH term(s) Aged ; Echocardiography ; Heart Aneurysm/diagnostic imaging ; Heart Aneurysm/surgery ; Heart Ventricles/diagnostic imaging ; Heart Ventricles/surgery ; Humans ; Male ; Stroke Volume ; Ventricular Function, Left
    Language Japanese
    Publishing date 2021-05-11
    Publishing country Japan
    Document type Case Reports ; Journal Article
    ZDB-ID 603899-2
    ISSN 0021-5252
    ISSN 0021-5252
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article: Benefit of Continuation of Low-Dose Imatinib for Gastrointestinal Stromal Tumors despite Adverse Events with Regular-Dose Imatinib.

    Katsumata, Ryo / Monobe, Yasumasa / Katata, Yosuke / Fujiwara, Hideyo / Urano, Takashi / Akagi, Akihisa / Tsujimoto, Kotone / Konishi, Takako / Manabe, Noriaki / Kamada, Tomoari / Kawamoto, Hirofumi / Yamatsuji, Tomoki / Naomoto, Yoshio

    Case reports in gastroenterology

    2023  Volume 17, Issue 1, Page(s) 109–116

    Abstract: Tyrosine kinase inhibitors (TKIs) such as imatinib improve the prognosis of patients with gastrointestinal stromal tumors (GISTs). However, treatment options for GISTs are still limited, and the continuation of TKIs is difficult due to adverse events in ... ...

    Abstract Tyrosine kinase inhibitors (TKIs) such as imatinib improve the prognosis of patients with gastrointestinal stromal tumors (GISTs). However, treatment options for GISTs are still limited, and the continuation of TKIs is difficult due to adverse events in some cases. The effectiveness of low-dose imatinib is unclear. We report 2 cases to show effectiveness of low-dose imatinib in patients with adverse events. The first case is a male in his early 60s with a history of intestinal GIST resection who was diagnosed with recurrent GIST with peritoneal dissemination. He was started on low-dose imatinib (300 mg) because of a history of subconjunctival hemorrhage after receiving postoperative imatinib. Follow-up contrast-enhanced ultrasonography revealed that the tumors had shrunk in size and number after 2 months of treatment with 300-mg imatinib. He continued this treatment and showed partial response for 8 months. The second case is a female in her late 70s with rectal GIST who was treated with imatinib 400 mg. Due to a severe skin lesion, she changed her treatment to sunitinib 2 months after initiation. However, new metastasis in the liver was confirmed after 4 months of administration of sunitinib. She underwent surgical esection of the rectal tumor to reduce the volume. After the surgery, low-dose imatinib (300 mg) with oral steroids was adopted. Follow-up confirmed the absence of recurrence at the rectum and no increase in hepatic tumor size for 18 months. Aggressive treatment with low-dose imatinib instead of discontinuation or alteration of treatment may benefit patients with unresectable and postoperative GISTs with sensible mutation to imatinib.
    Language English
    Publishing date 2023-02-17
    Publishing country Switzerland
    Document type Case Reports
    ZDB-ID 2440540-1
    ISSN 1662-0631
    ISSN 1662-0631
    DOI 10.1159/000529002
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article ; Online: Bioelectrical impedance analysis for perioperative water management in adult cardiovascular valve disease surgery.

    Watanabe, Tatsuya / Ishida, Naomasa / Takaoka, Munenori / Tsujimoto, Kotone / Kondo, Kensuke / Isoda, Ryutaro / Yukawa, Takuro / Tokunaga, Noriyuki / Ishida, Atsuhisa / Fukazawa, Takuya / Morita, Ichiro / Yoshida, Hideo / Kuinose, Masahiko / Yamatsuji, Tomoki

    Surgery today

    2020  Volume 51, Issue 6, Page(s) 1061–1067

    Abstract: Purpose: Bioelectrical impedance analysis (BIA) has been used recently to measure the body water of patients with acute heart failure. We used BIA in this study to better understand, and possibly identify a predictive marker for, perioperative water ... ...

    Abstract Purpose: Bioelectrical impedance analysis (BIA) has been used recently to measure the body water of patients with acute heart failure. We used BIA in this study to better understand, and possibly identify a predictive marker for, perioperative water behavior in cardiac surgery patients.
    Methods: We measured body water and studied its behavior in 44 patients undergoing surgery for cardiac valvular disease at our hospital. Measurements included the levels of extracellular water (ECW), intracellular water (ICW), and total body water, the edema index (EI), and the ratio of ECW to total body water. The first measured EI was defined as the "preoperative EI" and the maximum as the "peak EI".
    Results: A negative correlation was found between the preoperative EI and the preoperative estimated glomerular filtration rate (eGFR) (R = 0.644, p < 0.001). Positive correlations were found between the peak EI and the ICU stay (R = 0.625, p < 0.001), the peak EI and the ventilation time (R = 0.366, p < 0.01), and the preoperative EI and the ICU stay (R = 0.464, p = 0.026).
    Conclusion: The EI is possibly a predictive marker for perioperative water management in cardiac surgery.
    MeSH term(s) Aged ; Aged, 80 and over ; Biomarkers/metabolism ; Body Water/metabolism ; Edema/diagnosis ; Edema/etiology ; Edema/prevention & control ; Electric Impedance ; Extracellular Space/metabolism ; Female ; Glomerular Filtration Rate ; Heart Valve Diseases/complications ; Heart Valve Diseases/metabolism ; Heart Valve Diseases/physiopathology ; Heart Valve Diseases/surgery ; Humans ; Intracellular Space/metabolism ; Male ; Middle Aged ; Perioperative Care ; Perioperative Period ; Predictive Value of Tests ; Retrospective Studies ; Risk
    Chemical Substances Biomarkers
    Language English
    Publishing date 2020-12-01
    Publishing country Japan
    Document type Journal Article
    ZDB-ID 1115435-4
    ISSN 1436-2813 ; 0941-1291
    ISSN (online) 1436-2813
    ISSN 0941-1291
    DOI 10.1007/s00595-020-02184-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

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