LIVIVO - Search results -

Search results

Result 1 - 10 of total 24

Search options

Article ; Online: Potential Inhibition of COVID-19-driven Pneumonia by Immunosuppressive Therapy and anti-TNFα Antibodies: A Case Report.

Kunisaki, Reiko / Tsukiji, Jun / Kudo, Makoto

2020 Volume 14, Issue 12, Page(s) 1786–1787

MeSH term(s)	COVID-19/complications ; COVID-19/immunology ; COVID-19/physiopathology ; COVID-19/prevention & control ; Colitis, Ulcerative/complications ; Colitis, Ulcerative/drug therapy ; Colitis, Ulcerative/immunology ; Humans ; Immunosuppressive Agents/therapeutic use ; Infliximab/therapeutic use ; Male ; Middle Aged ; Patient Acuity ; Tumor Necrosis Factor-alpha/immunology
Chemical Substances	Immunosuppressive Agents ; TNF protein, human ; Tumor Necrosis Factor-alpha ; Infliximab (B72HH48FLU)
Keywords	covid19
Language	English
Publishing date	2020-05-26
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	2390120-2
ISSN	1876-4479 ; 1873-9946
ISSN (online)	1876-4479
ISSN	1873-9946
DOI	10.1093/ecco-jcc/jjaa105
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 6634: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
ab Jg. 2022: Lesesaal (EG)

Order via subito

This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Heme oxygenase-1 as an important predictor of the severity of COVID-19.

Hara, Yu / Tsukiji, Jun / Yabe, Aya / Onishi, Yoshika / Hirose, Haruka / Yamamoto, Masaki / Kudo, Makoto / Kaneko, Takeshi / Ebina, Toshiaki

PloS one

2022 Volume 17, Issue 8, Page(s) e0273500

Abstract: Background and objective: A cytokine storm is caused by inflammatory cells, including pro-inflammatory macrophage phenotype (M1), and play a critical role in the pathogenesis of COVID-19, in which diffuse alveolar damage occurs in the lungs due to ... ...

Abstract	Background and objective: A cytokine storm is caused by inflammatory cells, including pro-inflammatory macrophage phenotype (M1), and play a critical role in the pathogenesis of COVID-19, in which diffuse alveolar damage occurs in the lungs due to oxidative stress exposure. Heme oxygenase (HO)-1 is a stress-induced protein produced by the anti-inflammatory / anti-oxidative macrophage phenotype (M2), which also produces soluble CD163 (sCD163). In our study, we investigated and determined that serum HO-1 can be a predictive biomarker for assessing both the severity and the outcome of COVID-19 patients. Method: The serum concentrations of HO-1 and sCD163 of COVID-19 patients were measured on admission. The relationship between these biomarkers and other clinical parameters and outcomes were evaluated. Results: Sixty-four COVID-19 patients (11 mild, 38 moderate, and 15 severe cases) were assessed. The serum HO-1 tended to increase (11.0 ng/mL vs. 24.3 ng/mL vs. 59.6 ng/mL with severity). Serum HO-1 correlated with serum lactate dehydrogenase (R = 0.422), C-reactive protein (R = 0.463), and the ground glass opacity (GGO) and consolidation score (R = 0.625) of chest computed tomography. The serum HO-1 showed a better area under the curve (AUC) for predicting ICU admission than the serum sCD163 (HO-1; 0.816 and sCD163; 0.743). In addition, composite parameters including serum HO-1 and the GGO and consolidation score showed a higher AUC for predicting ICU admission than the AUC of a single parameter. Conclusion: Clinically, serum HO-1, reflecting the activation of M2, could be a very useful marker for evaluating disease severity and predicting prognoses for COVID-19 patients. In addition, controlling activated M2 might be a preventative COVID-19 therapeutic target.
MeSH term(s)	Biomarkers ; COVID-19 ; Heme Oxygenase-1/metabolism ; Humans ; Macrophages/metabolism ; Prognosis
Chemical Substances	Biomarkers ; HMOX1 protein, human (EC 1.14.14.18) ; Heme Oxygenase-1 (EC 1.14.14.18)
Language	English
Publishing date	2022-08-24
Publishing country	United States
Document type	Journal Article
ZDB-ID	2267670-3
ISSN	1932-6203 ; 1932-6203
ISSN (online)	1932-6203
ISSN	1932-6203
DOI	10.1371/journal.pone.0273500
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article: Potential inhibition of COVID-19-driven pneumonia by immunosuppressive therapy and anti-TNFα antibodies: a case report

Kunisaki, Reiko / Tsukiji, Jun / Kudo, Makoto

J. crohns. colitis

Keywords	covid19
Publisher	WHO
Document type	Article
Note	WHO #Covidence: #32473011
Database	COVID19

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Details ▾

Article ; Online: Potential Inhibition of COVID-19-driven Pneumonia by Immunosuppressive Therapy and anti-TNFα Antibodies

Kunisaki, Reiko / Tsukiji, Jun / Kudo, Makoto

Journal of Crohn's and Colitis ; ISSN 1873-9946 1876-4479

A Case Report

2020

Keywords	Gastroenterology ; General Medicine ; covid19
Language	English
Publisher	Oxford University Press (OUP)
Publishing country	uk
Document type	Article ; Online
DOI	10.1093/ecco-jcc/jjaa105
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: A first case report of nasopharyngeal Mycobacterium abscessus subspecies massiliense infection.

Oki, Yamato / Hatakeyama, Hiromitsu / Komatsu, Masanori / Isono, Yasuhiro / Ikemiyagi, Hidetaka / Tsukiji, Jun / Higa, Ryoko / Oridate, Nobuhiko

European journal of medical research

2021 Volume 26, Issue 1, Page(s) 109

Abstract: Background: Mycobacterium abscessus subspecies massiliense is a non-tuberculous mycobacteriosis and was subdivided from Mycobacterium abscessus in 2006. This article is the first report on nasopharyngitis caused by Mycobacterium abscessus subspecies ... ...

Abstract	Background: Mycobacterium abscessus subspecies massiliense is a non-tuberculous mycobacteriosis and was subdivided from Mycobacterium abscessus in 2006. This article is the first report on nasopharyngitis caused by Mycobacterium abscessus subspecies massiliense. Case presentation: A 45-year-old woman had an 18-month history of recurrent nasopharyngitis and presented with pain in the throat. Mycobacterial tissue culture and polymerase chain reaction testing revealed the presence of Mycobacterium abscessus subspecies massiliense in the nasopharyngeal tissue. This patient underwent surgery, followed by multiple rounds of chemotherapy with oral and intravenous antibiotic agents for 16 weeks. She has had no recurrence during the 56 weeks since treatment. Conclusion: It is difficult to detect the presence of Mycobacterium abscessus subspecies massiliense in a culture from the swabbing sample. The tissue culture from a biopsy specimen is mandatory for the identification of the species. Currently, no definite treatment policy is available and only empirical treatment is applied. This case is an important for the diagnosis and treatment of this bacterial infection on nasopharynx.
MeSH term(s)	Anti-Bacterial Agents/therapeutic use ; Female ; Humans ; Middle Aged ; Mycobacterium Infections, Nontuberculous/complications ; Mycobacterium Infections, Nontuberculous/microbiology ; Mycobacterium abscessus/isolation & purification ; Mycobacterium abscessus/pathogenicity ; Nasopharyngitis/drug therapy ; Nasopharyngitis/microbiology ; Prognosis
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2021-09-18
Publishing country	England
Document type	Case Reports ; Journal Article
ZDB-ID	1329381-3
ISSN	2047-783X ; 0949-2321
ISSN (online)	2047-783X
ISSN	0949-2321
DOI	10.1186/s40001-021-00578-8
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4636: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Detection of Mycobacterium tuberculosis derived DNA in circulating cell free DNA from a patient with disseminated infection with digital PCR.

Yamamoto, Masaki / Ushio, Ryota / Watanabe, Hiroki / Tachibana, Takayoshi / Tanaka, Masatsugu / Yokose, Tomoyuki / Tsukiji, Jun / Nakajima, Hideaki / Kaneko, Takeshi

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases

2017

Abstract: Mycobacterium tuberculosis (MTB) can disseminate to extra-pulmonary organs, particularly in severely immunosuppressed patients. Confirmation of active MTB infection is often difficult in subjects with contraindication for invasive procedures. We herein ... ...

Abstract	Mycobacterium tuberculosis (MTB) can disseminate to extra-pulmonary organs, particularly in severely immunosuppressed patients. Confirmation of active MTB infection is often difficult in subjects with contraindication for invasive procedures. We herein report a case of disseminated MTB infection after hematopoietic stem cell transplantation. Circulating cell free DNA of the patient showed positive amplification for a MTB complex specific sequence using digital PCR technique. MTB infection could be confirmed with positive acid fast stain and approved quantitative PCR assay using the liver tissue obtained at an autopsy. From this result, detection of MTB from circulating cell free DNA with this technique can be exploited as a less invasive diagnostic tool for pulmonary and extrapulmonary MTB infections.
Language	English
Publishing date	2017-11-14
Publishing country	Canada
Document type	Journal Article
ZDB-ID	1331197-9
ISSN	1878-3511 ; 1201-9712
ISSN (online)	1878-3511
ISSN	1201-9712
DOI	10.1016/j.ijid.2017.11.018
Database	MEDical Literature Analysis and Retrieval System OnLINE

In stock of ZB MED Cologne/Königswinter

Zs.A 4516: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾
- See ZB MED holdings
- Order with fees

Article ; Online: Salmonella enterica serovar Ohio septic arthritis and bone abscess in an immunocompetent patient

Kato Hideaki / Ueda Atsuhisa / Tsukiji Jun / Sano Kayoko / Yamada Mikiko / Ishigatsubo Yoshiaki

Journal of Medical Case Reports, Vol 6, Iss 1, p

a case report

2012 Volume 204

Abstract: Abstract Introduction Non-typhi Salmonella species cause severe extra-intestinal focal infection after occult bacteremia. Although the number of cases of non-typhi salmonellosis is increasing worldwide among patients with immunocompromising conditions ... ...

Abstract	Abstract Introduction Non-typhi Salmonella species cause severe extra-intestinal focal infection after occult bacteremia. Although the number of cases of non-typhi salmonellosis is increasing worldwide among patients with immunocompromising conditions such as human immunodeficiency virus infection, infection is uncommon in immunocompetent subjects. We report a case of septic arthritis and bone abscess due to a rare non-typhi Salmonella organism that developed after a prolonged asymptomatic period. Case presentation A 44-year-old Japanese immunocompetent man presented with acute-onset left knee pain and swelling. He had no history of food poisoning, and his most recent travel to an endemic area was 19 years ago. Salmonella enterica serovar Ohio was identified from samples of bone abscess and joint tissue. Arthrotomy and necrotic tissue debridement followed by intravenous ceftriaxone was successful. Conclusions Non-typhi Salmonella species only rarely cause extra-intestinal focal infections in immunocompetent patients. Our case suggests that non-typhi Salmonella species can cause severe focal infections many years after the occult bacteremia associated with food poisoning.
Keywords	Salmonella Ohio ; Non-typhi salmonellosis ; Extra-intestinal focal infection ; Immunocompetent patient ; Medicine ; R
Subject code	616
Language	English
Publishing date	2012-07-01T00:00:00Z
Publisher	BMC
Document type	Article ; Online
Database	BASE - Bielefeld Academic Search Engine (life sciences selection)

Full text online

Full text

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

Article ; Online: Salmonella enterica serovar Ohio septic arthritis and bone abscess in an immunocompetent patient: a case report.

Kato, Hideaki / Ueda, Atsuhisa / Tsukiji, Jun / Sano, Kayoko / Yamada, Mikiko / Ishigatsubo, Yoshiaki

Journal of medical case reports

2012 Volume 6, Page(s) 204

Abstract: Introduction: Non-typhi Salmonella species cause severe extra-intestinal focal infection after occult bacteremia. Although the number of cases of non-typhi salmonellosis is increasing worldwide among patients with immunocompromising conditions such as ... ...

Abstract	Introduction: Non-typhi Salmonella species cause severe extra-intestinal focal infection after occult bacteremia. Although the number of cases of non-typhi salmonellosis is increasing worldwide among patients with immunocompromising conditions such as human immunodeficiency virus infection, infection is uncommon in immunocompetent subjects. We report a case of septic arthritis and bone abscess due to a rare non-typhi Salmonella organism that developed after a prolonged asymptomatic period. Case presentation: A 44-year-old Japanese immunocompetent man presented with acute-onset left knee pain and swelling. He had no history of food poisoning, and his most recent travel to an endemic area was 19 years ago. Salmonella enterica serovar Ohio was identified from samples of bone abscess and joint tissue. Arthrotomy and necrotic tissue debridement followed by intravenous ceftriaxone was successful. Conclusions: Non-typhi Salmonella species only rarely cause extra-intestinal focal infections in immunocompetent patients. Our case suggests that non-typhi Salmonella species can cause severe focal infections many years after the occult bacteremia associated with food poisoning.
Language	English
Publishing date	2012-07-17
Publishing country	England
Document type	Journal Article
ZDB-ID	2269805-X
ISSN	1752-1947 ; 1752-1947
ISSN (online)	1752-1947
ISSN	1752-1947
DOI	10.1186/1752-1947-6-204
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Article ; Online: Decreased activities of daily living is a strong risk factor for liver injury by anti-tuberculosis drugs.

Horita, Nobuyuki / Miyazawa, Naoki / Yoshiyama, Takashi / Tsukahara, Toshinori / Takahashi, Ryohei / Tsukiji, Jun / Kato, Hideaki / Kaneko, Takeshi / Ishigatsubo, Yoshiaki

Respirology (Carlton, Vic.)

2013 Volume 18, Issue 3, Page(s) 474–479

Abstract: Background and objective: We evaluated the association between activities of daily living and drug-induced liver injury by anti-tuberculosis drugs.: Methods: This retrospective cohort study included adult inpatients with newly diagnosed smear- ... ...

Abstract	Background and objective: We evaluated the association between activities of daily living and drug-induced liver injury by anti-tuberculosis drugs. Methods: This retrospective cohort study included adult inpatients with newly diagnosed smear-positive lung tuberculosis treated with standard regimen in two hospitals. (n = 346; 63.6 ± 20.3 years old; 106 (30.6%) females). Activities of daily living was divided into 'independent' (Barthel Index (BI) 80-100, 60.4%) and 'decreased' (BI 0-75, 39.6%) categories. Liver injury was defined as the withdrawal or change of treatment regimen on the basis of the following criteria: serum transaminase concentrations were more than three times the upper limit of normal range with jaundice and/or hepatitis symptoms, or more than five times the upper limit of the normal range. Results: Compared with 'independent' patients, patients with 'decreased' activities of daily living had odds ratios for liver injury of 4.2 (P < 0.001) in univariate analysis and 5.7 (P = 0.002) in logistic regression analysis after adjusting for other risk factors. Conclusions: Decreased activity of daily living is a strong risk factor for liver injury among adult inpatients with newly diagnosed smear-positive lung tuberculosis treated using a standard regimen.
MeSH term(s)	Activities of Daily Living ; Aged ; Antitubercular Agents/adverse effects ; Antitubercular Agents/therapeutic use ; Chemical and Drug Induced Liver Injury/epidemiology ; Chemical and Drug Induced Liver Injury/etiology ; Female ; Humans ; Incidence ; Japan/epidemiology ; Male ; Middle Aged ; Odds Ratio ; Prognosis ; Retrospective Studies ; Risk Assessment/methods ; Risk Factors ; Tuberculosis, Pulmonary/drug therapy
Chemical Substances	Antitubercular Agents
Language	English
Publishing date	2013-04
Publishing country	Australia
Document type	Comparative Study ; Journal Article ; Multicenter Study
ZDB-ID	1435849-9
ISSN	1440-1843 ; 1323-7799
ISSN (online)	1440-1843
ISSN	1323-7799
DOI	10.1111/resp.12008
Database	MEDical Literature Analysis and Retrieval System OnLINE

Full text online

Accessible to users with ZB MED library card

In stock of ZB MED Cologne/Königswinter

Zs.A 4957: Show issues

Location:
Je nach Verfügbarkeit (siehe Angabe bei Bestand)
bis Jg. 1994: Bestellungen von Artikeln über das Online-Bestellformular
Jg. 1995 - 2021: Lesesall (2.OG)
ab Jg. 2022: Lesesaal (EG)

Order via subito

Details ▾

Article: YKL-40 is a Protective Biomarker for Fatty Liver in World Trade Center Particulate Matter-Exposed Firefighters.

Cho, Soo Jung / Echevarria, Ghislaine C / Lee, Young Im / Kwon, Sophia / Park, Kwan Yong / Tsukiji, Jun / Rom, William N / Prezant, David J / Nolan, Anna / Weiden, Michael D

Journal of molecular biomarkers & diagnosis

2015 Volume 5

Abstract: Background: Serum biomarkers of metabolic syndrome predict abnormal lung function in World Trade Center particulate matter (WTC-PM)-exposed Fire Department of New York (FDNY) rescue workers. In animal models, exposure to ambient PM induces non-alcoholic ...

Abstract	Background: Serum biomarkers of metabolic syndrome predict abnormal lung function in World Trade Center particulate matter (WTC-PM)-exposed Fire Department of New York (FDNY) rescue workers. In animal models, exposure to ambient PM induces non-alcoholic fatty liver disease (NAFLD), a well-known comorbidity of metabolic syndrome. YKL-40 is an inflammatory biomarker for both liver and lung disease. We tested if YKL-40 is a biomarker for NAFLD in this dust-exposed cohort. Methods: Using a nested case-control design, we studied 131 FDNY personnel who had Computer Tomography performed within 5 years post 9/11. NAFLD was defined by a liver/spleen attenuation ratio of ≤1. Serum biomarkers, lipid panel and liver function were measured in serum that had been drawn within 6 months of September 11, 2001. YKL-40 and chitotriosidase were assayed by ELISA. We tested biomarker and NAFLD association using logistic regression adjusted for age, BMI, and post-911 lung function. Results: NAFLD was present in 29/131 (22%) of the cohort. In a multivariable model increasing YKL-40 was protective while increasing triglyceride and alkaline phosphatase were risk factors for NAFLD. Conclusions: Increased YKL-40 is a protective biomarker in non-alcoholic fatty liver disease. Further studies may reveal a link between PM-induced lung and liver diseases.
Language	English
Publishing date	2015-02-25
Publishing country	United States
Document type	Journal Article
ISSN	2155-9929
ISSN	2155-9929
DOI	10.4172/2155-9929.1000174
Database	MEDical Literature Analysis and Retrieval System OnLINE

Order via subito

Inter-library loan at ZB MED

Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

To top

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Kategorien

Inter-library loan at ZB MED

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

Full text online

More links

Kategorien

Inter-library loan at ZB MED

More links

Kategorien

Order via subito

Full text online

More links

Kategorien

In stock of ZB MED Cologne/Königswinter

Order via subito

More links

Kategorien

Order via subito

Inter-library loan at ZB MED