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  1. Article: A rare pediatric cardiac anomaly: Quadricuspid aortic valve with aortic regurgitation.

    Brock, Michael / Tugertimur, Aykut / Schwartz, Matthew C

    Annals of pediatric cardiology

    2014  Volume 6, Issue 2, Page(s) 202–203

    Abstract: A quadricuspid aortic valve is rarely diagnosed in children, but it can be associated with significant aortic regurgitation. It is important for pediatric cardiologists to be aware of this pathologic entity. We present a nine-year-old male, diagnosed ... ...

    Abstract A quadricuspid aortic valve is rarely diagnosed in children, but it can be associated with significant aortic regurgitation. It is important for pediatric cardiologists to be aware of this pathologic entity. We present a nine-year-old male, diagnosed with a quadricuspid aortic valve and mild aortic regurgitation.
    Language English
    Publishing date 2014-02-13
    Publishing country India
    Document type Case Reports
    ZDB-ID 2430956-4
    ISSN 0974-5149 ; 0974-2069
    ISSN (online) 0974-5149
    ISSN 0974-2069
    DOI 10.4103/0974-2069.115285
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Examining the Utility of Coronary Artery Lack of Tapering and Perivascular Brightness in Incomplete Kawasaki Disease.

    Rabinowitz, Edon J / Rubin, Lorry G / Desai, Kinjal / Hayes, Denise A / Tugertimur, Aykut / Kwon, Elena N / Dhanantwari, Preeta / Misra, Nilanjana / Stoffels, Guillaume / Blaufox, Andrew D / Mitchell, Elizabeth

    Pediatric cardiology

    2018  Volume 40, Issue 1, Page(s) 147–153

    Abstract: Background: In 2017, the AHA published revised guidelines for the diagnosis of Kawasaki disease (KD). In the absence of compelling data supporting or refuting the utility of lack of tapering (LT) and perivascular brightness (PB), expert panel consensus ... ...

    Abstract Background: In 2017, the AHA published revised guidelines for the diagnosis of Kawasaki disease (KD). In the absence of compelling data supporting or refuting the utility of lack of tapering (LT) and perivascular brightness (PB), expert panel consensus removed LT and PB from consideration. We hypothesize that LT and PB are unreliable, subjective findings, non-specific to KD, which can be seen in systemic febrile illnesses without KD and in normal controls.
    Methods: We performed a single-center retrospective study from 1/2008 to 12/2016. De-identified coronary artery (CA) echocardiographic clips from patients 0-10 years old were interpreted blindly by six pediatric cardiologists. Subjects were grouped as follows: (1) healthy: afebrile with benign murmur, (2) KD: IVIG treatment, 4-5 clinical criteria at presentation, (3) incomplete KD (iKD): IVIG, 1-3 clinical criteria, (4) Febrile: ≥3 days of fever, no IVIG, KD not suspected. The presence or absence of LT and PB was recorded. Inter-rater and intra-rater reliabilities were analyzed using intra-class correlation coefficient, Fleiss' Kappa and Cohen's Kappa coefficients.
    Results: We interpreted 117 echocardiograms from healthy (27), KD (30), iKD (32), and febrile (28) subjects. Analysis showed moderate agreement in CA z score measurements. LT and PB were observed by most readers in control groups. LT exhibited fair inter-reader agreement (reliability coefficient 0.36) and PB slight inter-reader agreement (reliability coefficient 0.13). Intra-rater reliability was inconsistent for both parameters.
    Conclusions: LT and PB are subjective, poorly reproducible features that can be seen in febrile patients without KD and in healthy children.
    MeSH term(s) Case-Control Studies ; Child ; Child, Preschool ; Coronary Vessels/diagnostic imaging ; Echocardiography ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Mucocutaneous Lymph Node Syndrome/classification ; Mucocutaneous Lymph Node Syndrome/diagnostic imaging ; Reproducibility of Results ; Retrospective Studies
    Language English
    Publishing date 2018-09-08
    Publishing country United States
    Document type Journal Article
    ZDB-ID 800857-7
    ISSN 1432-1971 ; 0172-0643
    ISSN (online) 1432-1971
    ISSN 0172-0643
    DOI 10.1007/s00246-018-1971-z
    Database MEDical Literature Analysis and Retrieval System OnLINE

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