LIVIVO - The Search Portal for Life Sciences

zur deutschen Oberfläche wechseln
Advanced search

Search results

Result 1 - 10 of total 73

Search options

  1. Article ; Online: Influence of interaction of cerebral fluids on ventricular deformation: A mathematical approach.

    Valova, Galina / Bogomyakova, Olga / Tulupov, Andrey / Cherevko, Alexander

    PloS one

    2022  Volume 17, Issue 2, Page(s) e0264395

    Abstract: This paper describes the effects of the interaction of cerebral fluids (arterial, capillary and venous blood, cerebrospinal fluid) on ventricular wall displacement and periventricular pressure using a mathematical multiphase poroelasticity model for the ... ...

    Abstract This paper describes the effects of the interaction of cerebral fluids (arterial, capillary and venous blood, cerebrospinal fluid) on ventricular wall displacement and periventricular pressure using a mathematical multiphase poroelasticity model for the cerebral parenchyma. The interaction of cerebral fluids is given by a set of four numerical coefficients. A multiple linear regression with interaction is constructed that allows us to quantify the effect of these coefficients on the average ventricular wall displacement. The prevailing influence of an arterial-liquor component was observed. The sets of coefficients associated with such pathological conditions were found: normal pressure hydrocephalus, intracranial hypertension, and replacement ventriculomegaly under a prolonged hypoperfusion.
    MeSH term(s) Cerebral Ventricles/diagnostic imaging ; Cerebral Ventricles/physiopathology ; Humans ; Hydrocephalus, Normal Pressure/diagnostic imaging ; Hydrocephalus, Normal Pressure/physiopathology ; Models, Neurological
    Language English
    Publishing date 2022-02-28
    Publishing country United States
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 2267670-3
    ISSN 1932-6203 ; 1932-6203
    ISSN (online) 1932-6203
    ISSN 1932-6203
    DOI 10.1371/journal.pone.0264395
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  2. Article ; Online: The glymphatic system and meningeal lymphatics of the brain: new understanding of brain clearance.

    Yankova, Galina / Bogomyakova, Olga / Tulupov, Andrey

    Reviews in the neurosciences

    2021  Volume 32, Issue 7, Page(s) 693–705

    Abstract: The glymphatic system and meningeal lymphatics have recently been characterized. Glymphatic system is a glia-dependent system of perivascular channels, and it plays an important role in the removal of interstitial metabolic waste products. The meningeal ... ...

    Abstract The glymphatic system and meningeal lymphatics have recently been characterized. Glymphatic system is a glia-dependent system of perivascular channels, and it plays an important role in the removal of interstitial metabolic waste products. The meningeal lymphatics may be a key drainage route for cerebrospinal fluid into the peripheral blood, may contribute to inflammatory reaction and central nervous system (CNS) immune surveillance. Breakdowns and dysfunction of the glymphatic system and meningeal lymphatics play a crucial role in age-related brain changes, the pathogenesis of neurovascular and neurodegenerative diseases, as well as in brain injuries and tumors. This review discusses the relationship recently characterized meningeal lymphatic vessels with the glymphatic system, which provides perfusion of the CNS with cerebrospinal and interstitial fluids. The review also presents the results of human studies concerning both the presence of meningeal lymphatics and the glymphatic system. A new understanding of how aging, medications, sleep and wake cycles, genetic predisposition, and even body posture affect the brain drainage system has not only changed the idea of brain fluid circulation but has also contributed to an understanding of the pathology and mechanisms of neurodegenerative diseases.
    MeSH term(s) Brain ; Central Nervous System ; Glymphatic System ; Humans ; Lymphatic Vessels ; Neurodegenerative Diseases
    Language English
    Publishing date 2021-02-23
    Publishing country Germany
    Document type Journal Article ; Research Support, Non-U.S. Gov't ; Review
    ZDB-ID 639035-3
    ISSN 2191-0200 ; 0334-1763
    ISSN (online) 2191-0200
    ISSN 0334-1763
    DOI 10.1515/revneuro-2020-0106
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 3038: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  3. Book ; Online: Weakly supervised semantic segmentation of tomographic images in the diagnosis of stroke

    Dobshik, Anna / Tulupov, Andrey / Berikov, Vladimir

    2021  

    Abstract: This paper presents an automatic algorithm for the segmentation of areas affected by an acute stroke on the non-contrast computed tomography brain images. The proposed algorithm is designed for learning in a weakly supervised scenario when some images ... ...

    Abstract This paper presents an automatic algorithm for the segmentation of areas affected by an acute stroke on the non-contrast computed tomography brain images. The proposed algorithm is designed for learning in a weakly supervised scenario when some images are labeled accurately, and some images are labeled inaccurately. Wrong labels appear as a result of inaccuracy made by a radiologist in the process of manual annotation of computed tomography images. We propose methods for solving the segmentation problem in the case of inaccurately labeled training data. We use the U-Net neural network architecture with several modifications. Experiments on real computed tomography scans show that the proposed methods increase the segmentation accuracy.

    Comment: 6 pages, 3 figures, 1 table
    Keywords Electrical Engineering and Systems Science - Image and Video Processing ; Computer Science - Computer Vision and Pattern Recognition ; Computer Science - Machine Learning
    Subject code 006 ; 004
    Publishing date 2021-09-04
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  4. Article ; Online: Evaluation of the flow of cerebrospinal fluid as well as gender and age characteristics in patients with communicating hydrocephalus, using phase-contrast magnetic resonance imaging.

    Bogomyakova, Olga / Stankevich, Yu / Mesropyan, N / Shaybman, L / Tulupov, A

    Acta neurologica Belgica

    2016  Volume 116, Issue 4, Page(s) 495–501

    Abstract: To determine the difference in the velocity parameters of cerebrospinal fluid flow in patients with varying severity of communicating hydrocephalus compared to a group of healthy volunteers without hydrodynamic disorders. The study involved 35 subjects ... ...

    Abstract To determine the difference in the velocity parameters of cerebrospinal fluid flow in patients with varying severity of communicating hydrocephalus compared to a group of healthy volunteers without hydrodynamic disorders. The study involved 35 subjects with communicating hydrocephalus (25 subjects with Evans index of 0.31; 10 subject with Evans index of 0.46) and 62 healthy volunteers. The mean, volume, and peak flow velocities were determined at the different intracranial levels. Also were made an assessment of gender and age differences. Analysis of the differences between the mean values showed the progressive inhibition of cerebrospinal fluid outflow from the cranial cavity [in moderate communicating hydrocephalus-at 1.5 times (p < 0.05), in severe communicating hydrocephalus at 2-2.5 times (p < 0.01)], depending on the severity of enlargement of the ventricular system and, most likely, related to inhibition of its reabsorption. These changes may explain the clinical symptoms of subjects and serve as diagnostic criteria. Also it was revealed a significant influence of the factor of age on speed characteristics of the cerebrospinal fluid flow (F = 5.3303, p = 0.0003, for mean velocity).
    MeSH term(s) Adolescent ; Adult ; Age Factors ; Female ; Humans ; Hydrocephalus/cerebrospinal fluid ; Magnetic Resonance Imaging ; Male ; Middle Aged ; Young Adult
    Language English
    Publishing date 2016-12
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 127315-2
    ISSN 2240-2993 ; 0300-9009
    ISSN (online) 2240-2993
    ISSN 0300-9009
    DOI 10.1007/s13760-016-0608-3
    Database MEDical Literature Analysis and Retrieval System OnLINE

    Full text online

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Ui I Zs.57: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  5. Article: [Girgolav Semyon Semyonovich (1881-1957)].

    Grinev, M V / Tulupov, A N

    Vestnik khirurgii imeni I. I. Grekova

    2014  Volume 173, Issue 1, Page(s) 9–11

    MeSH term(s) General Surgery/history ; History, 19th Century ; History, 20th Century ; Humans ; Military Medicine/history ; USSR
    Language Russian
    Publishing date 2014
    Publishing country Russia (Federation)
    Document type Historical Article ; Journal Article
    ZDB-ID 603433-0
    ISSN 0042-4625
    ISSN 0042-4625
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 747: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  6. Book ; Online: Acute ischemic stroke lesion segmentation in non-contrast CT images using 3D convolutional neural networks

    Dobshik, A. V. / Verbitskiy, S. K. / Pestunov, I. A. / Sherman, K. M. / Sinyavskiy, Yu. N. / Tulupov, A. A. / Berikov, V. B.

    2023  

    Abstract: In this paper, an automatic algorithm aimed at volumetric segmentation of acute ischemic stroke lesion in non-contrast computed tomography brain 3D images is proposed. Our deep-learning approach is based on the popular 3D U-Net convolutional neural ... ...

    Abstract In this paper, an automatic algorithm aimed at volumetric segmentation of acute ischemic stroke lesion in non-contrast computed tomography brain 3D images is proposed. Our deep-learning approach is based on the popular 3D U-Net convolutional neural network architecture, which was modified by adding the squeeze-and-excitation blocks and residual connections. Robust pre-processing methods were implemented to improve the segmentation accuracy. Moreover, a specific patches sampling strategy was used to address the large size of medical images, to smooth out the effect of the class imbalance problem and to stabilize neural network training. All experiments were performed using five-fold cross-validation on the dataset containing non-contrast computed tomography volumetric brain scans of 81 patients diagnosed with acute ischemic stroke. Two radiology experts manually segmented images independently and then verified the labeling results for inconsistencies. The quantitative results of the proposed algorithm and obtained segmentation were measured by the Dice similarity coefficient, sensitivity, specificity and precision metrics. Our proposed model achieves an average Dice of $0.628\pm0.033$, sensitivity of $0.699\pm0.039$, specificity of $0.9965\pm0.0016$ and precision of $0.619\pm0.036$, showing promising segmentation results.

    Comment: 18 pages, 4 figures, 2 tables
    Keywords Electrical Engineering and Systems Science - Image and Video Processing ; Computer Science - Computer Vision and Pattern Recognition
    Subject code 006
    Publishing date 2023-01-17
    Publishing country us
    Document type Book ; Online
    Database BASE - Bielefeld Academic Search Engine (life sciences selection)

    Full text online

    More links

    Kategorien

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  7. Article: Environmental hazard assessment and forecast of economic damage from industrial accidents

    Porfirʹev, Boris N / Tulupov, A. S

    Studies on Russian economic development : the official journal of the Institute of Economic Forecasting, Russian Academy of Sciences Vol. 28, No. 6 , p. 600-607

    2017  Volume 28, Issue 6, Page(s) 600–607

    Author's details B.N. Porfiryev, A.S. Tulupov
    Keywords Störfall ; Umweltbelastung ; Wirkungsanalyse ; Prognoseverfahren ; Baschkortostan
    Language English
    Dates of publication 2017-9999
    Publisher Pleiades Publ
    Publishing place Moscow
    Document type Article
    Note Aus dem Russischen übersetzt
    ZDB-ID 913675-7
    ISSN 1054-6588
    Database ECONomics Information System

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  8. Article ; Online: Viability of Bacteriophages in the Complex Hydrogel Wound Dressings

    Beschastnov, V V / Ryabkov, M G / Leontiev, A E / Tulupov, A A / Yudanova, T N / Shirokova, I Yu / Belyanina, N А / Kovalishena, O V

    Sovremennye tekhnologii v meditsine

    2021  Volume 13, Issue 2, Page(s) 32–38

    Abstract: Using bacteriophages to overcome the increasing resistance of microorganisms to antibiotics is a novel research venue of clinical importance. Among other challenges, this technique is expected to create and maintain an adequate local concentration of ... ...

    Abstract Using bacteriophages to overcome the increasing resistance of microorganisms to antibiotics is a novel research venue of clinical importance. Among other challenges, this technique is expected to create and maintain an adequate local concentration of bacteriophages at the site of application. In addition, the possibility of combining the phage preparation with antioxidants and anesthetics may provide new options for stimulating the reparative process.
    Materials and methods: A technique for incorporating bacteriophages into the complex hydrogel wound dressing
    Results: In all samples containing bacteriophages, the presence of viable and lytically active phages was noted within 1 to 7 days, as evidenced by the "negative colonies" on the culture lawns. On days 1 to 3, no secondary growth was recorded in the phage-containing samples. In hydrogel samples containing phages, succinic acid, and lidocaine, secondary bacterial colonies were detected starting from day 4 indicating some reduction in the lytic activity.
    Conclusion: The results suggest that bacteriophages immobilized in the hydrogel maintain their viability and lytic activity, and this activity persists when the phages are combined with succinic acid and lidocaine.
    MeSH term(s) Bacteriophages ; Bandages ; Hydrogels ; Polyvinyl Alcohol ; Staphylococcus aureus
    Chemical Substances Hydrogels ; Polyvinyl Alcohol (9002-89-5)
    Language English
    Publishing date 2021-04-30
    Publishing country Russia (Federation)
    Document type Journal Article
    ISSN 2309-995X
    ISSN (online) 2309-995X
    DOI 10.17691/stm2021.13.2.03
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

    Inter-library loan at ZB MED

    Your chosen title can be delivered directly to ZB MED Cologne location if you are registered as a user at ZB MED Cologne.

  9. Article: [The detox and antioxidant activity of the reamberine in the complex treatment of the acute destructive lung disease].

    Fufaev, E E / Tulupov, A N

    Khirurgiia

    2012  , Issue 4, Page(s) 43–47

    MeSH term(s) Acute Lung Injury/drug therapy ; Antioxidants/therapeutic use ; Humans ; Lung Diseases/drug therapy ; Meglumine/analogs & derivatives ; Meglumine/therapeutic use ; Succinates/therapeutic use
    Chemical Substances Antioxidants ; Reamberin ; Succinates ; Meglumine (6HG8UB2MUY)
    Language Russian
    Publishing date 2012
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 419230-8
    ISSN 2309-5628 ; 0023-1207
    ISSN (online) 2309-5628
    ISSN 0023-1207
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 740: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

  10. Article: Diagnostika i lechenie povrezhdenii pochek pri zakrytykh travmakh i koloto-rezanykh raneniyakh zhivota.

    Gavrishchuk, Ya V / Manukovsky, V A / Tulupov, A N / Demko, A E / Kandyba, D V / Kolchanov, E A / Kiselev, M A / Kazankin, A S / Pravosud, M N

    Khirurgiia

    2022  , Issue 9, Page(s) 56–64

    Abstract: Objective: To improve treatment outcomes in victims with kidney damage following blunt and stab abdominal trauma by using of minimally invasive methods of diagnosis and treatment.: Material and methods: About 1.2-3.5% of all victims arrived to the ... ...

    Title translation Diagnosis and treatment of kidney damage following stab and blunt abdominal injuries.
    Abstract Objective: To improve treatment outcomes in victims with kidney damage following blunt and stab abdominal trauma by using of minimally invasive methods of diagnosis and treatment.
    Material and methods: About 1.2-3.5% of all victims arrived to the Dzhanelidze St. Petersburg Research Institute for Emergency Care have kidney injuries. We analyzed the results of treatment of 117 patients with isolated and combined blunt and stab abdominal injuries. The retrospective (2014-2017) group included 62 victims, and the prospective (2018-2021) group enrolled 55 patients who were treated according to the new algorithm. This algorithm included non-surgical and minimally invasive management for patients with systolic blood pressure >90 mm Hg after contrast-enhanced CT. Angiography with selective embolization was required for ongoing bleeding. We analyzed incidence of open interventions, organ-sparing procedures, complications, duration of treatment and mortality. Between-group differences were assessed using the χ
    Results: In both groups, kidney damage in most victims with abdominal trauma was due to road accident and catatrauma. Most patients had combined abdominal injuries, mainly in combination with head and chest lesions. Severity of injuries and clinical condition were similar in both groups. In the retrospective group, there were 9 laparotomies with nephrectomy. Nephrorraphy was performed in 8 cases, kidney vessel suture - in 4 patietns. In the prospective group, nephrectomy was performed in 3 patients with unstable hemodynamics and injuries AAST grade V. Nephrorraphy was performed in 4 victims. In one case, vascular suture was applied for tangential vein damage. All laparoscopies in both groups were diagnostic without nephrectomy. We used non-surgical treatment in 34 patients of the prospective group. One patient underwent angiography and selective embolization of renal artery branches. There were no significant between-group differences in the incidence of infectious and non-infectious complications. Mortality rate was 30.6% (
    Conclusion: The proposed algorithm for kidney injury made it possible to reduce the incidence of laparoscopies and laparotomies by 2 times, preserve the damaged kidney in 94.5% of cases and avoid invasive treatment in 62% of victims.
    MeSH term(s) Abdominal Injuries/complications ; Abdominal Injuries/diagnosis ; Abdominal Injuries/surgery ; Humans ; Kidney/injuries ; Retrospective Studies ; Wounds, Nonpenetrating/complications ; Wounds, Nonpenetrating/diagnosis ; Wounds, Nonpenetrating/surgery ; Wounds, Stab/complications ; Wounds, Stab/diagnosis ; Wounds, Stab/surgery
    Language Russian
    Publishing date 2022-06-01
    Publishing country Russia (Federation)
    Document type Journal Article
    ZDB-ID 419230-8
    ISSN 2309-5628 ; 0023-1207
    ISSN (online) 2309-5628
    ISSN 0023-1207
    DOI 10.17116/hirurgia202209156
    Database MEDical Literature Analysis and Retrieval System OnLINE

    More links

    Kategorien

    In stock of ZB MED Cologne/Königswinter

    Zs.B 740: Show issues Location:
    Je nach Verfügbarkeit (siehe Angabe bei Bestand)
    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

    Order via subito

    This service is chargeable due to the Delivery terms set by subito. Orders including an article and supplementary material will be classified as separate orders. In these cases, fees will be demanded for each order.

To top