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Article: Oncologic outcomes of postoperative adjuvant versus salvage radiotherapy in prostate cancer.

Şendoğan, Furkan / Turan, Turgay / Keser, Ferhat / Hancilar, Tayfun / Atis, Gokhan / Yildirim, Asif

2023 Volume 76, Issue 2, Page(s) 109–115

Abstract: Introduction: The aim of this study was to compare the long-term oncological results of patients with the diagnosis of prostate cancer who underwent open radical retropubic prostatectomy (RRP) and subsequent adjuvant (ART) or salvage radiotherapy (SRT).! ...

Abstract	Introduction: The aim of this study was to compare the long-term oncological results of patients with the diagnosis of prostate cancer who underwent open radical retropubic prostatectomy (RRP) and subsequent adjuvant (ART) or salvage radiotherapy (SRT). Material and methods: A total of 145 patients underwent open RRP for prostate cancer and subsequent ART or SRT postoperatively between 2010 and 2019. ART (n = 56) is defined as the group of patients with prostate-specific antigen (PSA) <0.2 ng/mL or with positive lymph nodes without PSA increase who received radiotherapy within the first 6 months of urinary continence. SRT (n = 89) is defined as the group of patients with PSA >0.2 ng/mL who received RT before PSA amounted to 0.5 ng/mL. Results: Statistically no significant difference was found between groups in terms of age, prostate volume, final pathology Gleason scores, lymphadenectomy, duration of androgen deprivation therapy (ADT), time to relapse after radiotherapy, development of biochemical recurrence and disease progression. Extraprostatic extension, seminal vesicle invasion and surgical margin positivity were significantly higher in the ART group. No difference was found between the groups in terms of biochemical recurrence-free survival, while cancer-specific survival and overall survival rates were significantly higher in the SRT group. Conclusions: It was found that cancer-specific and overall survival was better in the SRT group. It will be more appropriate to follow-up until the recurrence and then to perform SRT after the relapse in the postoperative period.
Language	English
Publishing date	2023-03-31
Publishing country	Poland
Document type	Journal Article
ZDB-ID	2672528-9
ISSN	2080-4873 ; 2080-4806
ISSN (online)	2080-4873
ISSN	2080-4806
DOI	10.5173/ceju.2023.190
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Article ; Online: The Impact of Histological Variants on Oncological Outcomes in Patients with Muscle Invasive Bladder Cancer Treated with Radical Cystectomy.

Efiloğlu, Özgür / Çakıcı, Mehmet Çağlar / Kır, Gözde / İplikçi, Ayberk / Turan, Turgay / Cecikoğlu, Gözde Ecem / Yıldırım, Asıf

Urology research & practice

2023 Volume 49, Issue 4, Page(s) 246–252

Abstract: Objective: Bladder cancer is a heterogeneous entity characterized by a wide range of different morphologies. The aim of this study was to investigate the prognostic effect of bladder tumor with variant histology that is treated with radical cystectomy ... ...

Abstract	Objective: Bladder cancer is a heterogeneous entity characterized by a wide range of different morphologies. The aim of this study was to investigate the prognostic effect of bladder tumor with variant histology that is treated with radical cystectomy on oncological outcomes. Methods: One hundred eighty-six patients who underwent radical cystectomy between September 2001 and June 2020 were included in the study. The patients were divided into 2 groups variant histology group (n = 54) and transitional cell cancer group (n = 132). Clinicopathologic data were compared between the two groups. Results: The groups were similar in terms of demographic characteristics. In the mul- tivariate analysis of cancer-specific survival in transitional cell cancer against variant histology, high-grade detection of primary transurethral bladder tumor pathology, cystectomy pT, cystectomy positive lymph node, and positive surgical margin in cys- tectomy were determined to be statistically significant. Diagnosis of pT2 and high grade of primary transurethral bladder tumor pathology, cystectomy ≥ pT3, cystec- tomy positive lymph node, and positive surgical margin in cystectomy were statis- tically significant in multivariate analysis of overall survival. Cancer-specific survival time was estimated at 65.1 ± 8.3 months for variant histology and 134.2 ± 10.4 months for transitional cell cancer (P=.004). The estimated overall survival time was 61.9 ± 8.0 months in variant histology and 119.0 ± 9.8 months in transitional cell cancer (P = .014). Conclusion: Pathological features and prognosis of bladder cancer with variant histol- ogies are worse than those of pure urothelial bladder cancer. Overall survival and can- cer-specific survival are shorter in bladder cancer with variant histology than in pure urothelial bladder cancer. Following the diagnosis of variant histology in transurethral bladder tumor, poor prognosis must be considered in the treatment plan.
Language	English
Publishing date	2023-10-25
Publishing country	Turkey
Document type	Journal Article
ISSN	2980-1478
ISSN (online)	2980-1478
DOI	10.5152/tud.2023.22223
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Article ; Online: The Relationship Between Lymphocyte Subtypes with Clinicopathological Features and Prognosis of Prostate Cancer in Patients Undergoing Radical Prostatectomy.

Sendogan, Furkan / Turan, Turgay / Erman, Hayriye / Danacioglu, Yavuz Onur / Isman, Ferruh Kemal / Atis, Ramazan Gokhan / Silay, M Selcuk / Caskurlu, Turhan / Yildirim, Asif

Urology research & practice

2023 Volume 49, Issue 4, Page(s) 253–258

Abstract: Objective: The immune system has an essential role in the development of cancer by showing both anti-tumor and pro-tumor activities. Understanding the immune func- tion of patients with malignancy is of clinical importance for the evaluation, treatment, ...

Abstract	Objective: The immune system has an essential role in the development of cancer by showing both anti-tumor and pro-tumor activities. Understanding the immune func- tion of patients with malignancy is of clinical importance for the evaluation, treatment, and prognosis of the disease. We aimed to evaluate lymphocyte subtypes in peripheral blood samples of prostate cancer patients and their relationship with clinicopathologi- cal features and prognosis. Methods: One hundred thirty-seven patients who underwent open radical prosta- tectomy were included in our study. The percentages of CD3+T lymphocyte, CD19+ B lymphocyte, CD16/56 natural killer cells, CD4+ helper T lymphocyte, CD8+ cytotoxic T lymphocyte, and CD45 total lymphocyte were evaluated for each patient using the blood sample taken into a hemogram tube before surgery. Results: The pathological stage was T2 for 64 of the cases and T3 for 73. The mean follow-up period of the patients was 12.81 ± 6.20 months. The CD3+/CD4+ counts of the patients with pathological stage T2 were found to be statistically significantly higher than stage T3. There was a statistically significant negative correlation between the prostate-specific antigen levels and CD3+/CD4+ percentages of the patients. There was no statistical significance between the percentages of lymphocyte subtypes and the presence of surgical margin, biochemical recurrence, adjuvant therapy, and cancer upgrade. Conclusion: We consider that the increase in the pathological stage and prostate-spe- cific antigen value and the decrease in the number of CD4+ T lymphocyte subtypes may be prognostic markers in prostate cancer patients.
Language	English
Publishing date	2023-10-25
Publishing country	Turkey
Document type	Journal Article
ISSN	2980-1478
ISSN (online)	2980-1478
DOI	10.5152/tud.2023.22220
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Article ; Online: Effects of androgen deprivation therapy on metabolic markers and bioelectrical impedance analyze in prostate cancer patients.

Çakıcı, Mehmet Çağlar / Can, Bülent / Kazan, Özgür / Efiloğlu, Özgür / Şendoğan, Furkan / Uçar, Taha / Turan, Turgay / Yıldırım, Asıf

Revista internacional de andrologia

2022 Volume 20, Issue 2, Page(s) 96–101

Abstract: Introduction and objectives: Prostate cancer (PCa) is the most widespread malignancy within men. Androgen deprivation therapy (ADT), which is the central component of advanced PCa treatment, causes side effects. The goal of this study was to examine the ...

Abstract	Introduction and objectives: Prostate cancer (PCa) is the most widespread malignancy within men. Androgen deprivation therapy (ADT), which is the central component of advanced PCa treatment, causes side effects. The goal of this study was to examine the metabolic changes and bioelectrical impedance analysis differences in PCa patients who received ADT. Materials and methods: After age-related match-pair analysis, a total of 519 patients with PCa and control group who had benign disease were enrolled in the study. Biochemical blood parameters and TANITA measurements were recorded for all patients. Patients were categorized into three groups, ADT group (Group 1, n=124) and non-ADT group (Group 2, n=248), control group (Group 3, n=147). Results: The mean age of groups was similar. Body mass index, waist circumference, body fat mass and fat ratio, which were among the TANITA parameters, were higher in group 1 (p<0.05). Total cholesterol, high density lipoprotein, non- high density lipoprotein, triglycerids and fasting blood glucose values were also higher in group 1 (p<0.05). Myocardial infarction and metabolic syndrome rates were also higher in this group. Conclusions: While the use of ADT is manifested by an increase in fat mass and fat ratio in body composition, it negatively affects waist circumference measurements. It is associated with metabolically unfit body composition changes that predispose to diabetes mellitus and may increase cardio-vascular disease. For this reason, it is necessary to be careful about metabolic and endocrinological diseases in long-term therapy.
MeSH term(s)	Androgen Antagonists/adverse effects ; Androgens/therapeutic use ; Electric Impedance ; Humans ; Lipoproteins, HDL/therapeutic use ; Male ; Prostatic Neoplasms/drug therapy ; Prostatic Neoplasms/pathology
Chemical Substances	Androgen Antagonists ; Androgens ; Lipoproteins, HDL
Language	English
Publishing date	2022-02-01
Publishing country	Spain
Document type	Journal Article
ISSN	1698-0409
ISSN (online)	1698-0409
DOI	10.1016/j.androl.2020.10.007
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Article ; Online: Changes in Antimicrobial Resistance of Urinary Tract Infections in Adult Patients over a 5-Year Period.

Caskurlu, Hulya / Culpan, Meftun / Erol, Bulent / Turan, Turgay / Vahaboglu, Haluk / Caskurlu, Turhan

Urologia internationalis

2020 Volume 104, Issue 3-4, Page(s) 287–292

Abstract: Objectives: We aimed to determine the most common bacteria that cause urinary tract infections (UTIs), the rate of antibiotic resistance of these uropathogens, and the changes in resistance rates over the years for adult patients diagnosed with UTIs.: ...

Abstract	Objectives: We aimed to determine the most common bacteria that cause urinary tract infections (UTIs), the rate of antibiotic resistance of these uropathogens, and the changes in resistance rates over the years for adult patients diagnosed with UTIs. Methods: We retrospectively reviewed urine cultures and antibiotic susceptibility results of patients >17 years of age from our outpatient clinic between 2014 and 2018. The most common uropathogens and their antibiotic resistance rates were identified in different age groups (18-39, 40-59, and ≥60 years) and with respect to gender and date of admission. In addition, the change in antibiotic resistance of Escherichia coli between 2014 and 2018 was also examined. Results: A total of 9,556 positive urine cultures were included. The most common uropathogen was E. coli, and its prevalence was higher in females than males (70.6 vs. 53.4%, respectively). The majority of isolates were from patients ≥60 years of age. E. coli resistance was most pronounced for ampicillin (61.56%), followed by trimeth-oprim-sulfamethoxazole (49.80%), amoxicillin-clavulanic acid (34.69%), and cefazolin (30.72%). E. coli resistance to ampicillin, nitrofurantoin, cefepime, ciprofloxacin, fosfomycin, and amoxicillin-clavulanic acid increased significantly with time (all p = 0.001). For E. coli, resistance to ciprofloxacin, one of the most commonly used antibiotics for UTI, increased from 17 to 43% from 2014 to 2018. Conclusion: Most of the uropathogens displayed high resistance to ampicillin, tri-methoprim-sulfamethoxazole, and amoxicillin-clavulanic acid, and were susceptible to meropenem, ertapenem, and imipenem. Fosfomycin and cefepime were useful in the empirical treatment of community-acquired UTIs. A surprisingly high increase was observed in the resistance of E. coli to antimicrobial agents from 2014 to 2018.
MeSH term(s)	Adolescent ; Adult ; Anti-Bacterial Agents/pharmacology ; Anti-Bacterial Agents/therapeutic use ; Drug Resistance, Bacterial ; Escherichia coli/drug effects ; Female ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Time Factors ; Urinary Tract Infections/drug therapy ; Urinary Tract Infections/microbiology ; Young Adult
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2020-01-15
Publishing country	Switzerland
Document type	Journal Article
ZDB-ID	204045-1
ISSN	1423-0399 ; 0042-1138
ISSN (online)	1423-0399
ISSN	0042-1138
DOI	10.1159/000504415
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Article: Supraclavicular lymph node as the first presentation and late skin metastasis: an unusual clinical course for prostate cancer.

Çulpan, Meftun / Yıldırım, Asıf / Turan, Turgay / Çaşkurlu, Turhan

Turkish journal of urology

2017 Volume 44, Issue 1, Page(s) 75–78

Abstract: Prostate cancer is the most common non-cutaneous malignancy and the second cause of cancer death in men. Despite improvements in diagnostic methods, the primary diagnosis of a number of patients may still be on metastatic stage. Cutaneous and ... ...

Abstract	Prostate cancer is the most common non-cutaneous malignancy and the second cause of cancer death in men. Despite improvements in diagnostic methods, the primary diagnosis of a number of patients may still be on metastatic stage. Cutaneous and supraclavicular lymph nodes are very rare metastatic sites for prostate cancer. In this report we present an extremely rare prostate cancer case diagnosed with supraclavicular lymph node and then developed cutaneous metastasis. A 64 year-old man was admitted to an internal medicine outpatient clinic with supraclavicular lymph node and biopsy of lymph node showed an adenocarcinoma. After prostate cancer diagnosis, patient was treated with androgen deprivation therapy, docetaxel chemotherapy and abiraterone acetate, respectively. While abiraterone treatment, cutaneous metastasis developed in inguinal area and diagnosis was confirmed by skin biopsy. In some cases, atypical symptoms may guide us to find disease with aggressive clinics. That's why, physical rectal examination and prostate specific antigen measurements should be kept in mind for prostate cancer in male patients with supraclavicular lymph node or atypical metastasis.
Language	English
Publishing date	2017-12-19
Publishing country	Turkey
Document type	Journal Article
ISSN	2149-3235
ISSN	2149-3235
DOI	10.5152/tud.2017.29660
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Article ; Online: Reconstruction of an Incompletely Amputated Penis with The Radical Penile Crural Dissection and Radial Forearm Free Flap.

Turan, Turgay / Erol, Bulent / Ulus, Ismail / Guven, Erdem / Caskurlu, Turhan

Urology journal

2018 Volume 15, Issue 2, Page(s) 55–57

MeSH term(s)	Adult ; Amputation, Traumatic/surgery ; Dissection ; Humans ; Male ; Penis/injuries ; Reconstructive Surgical Procedures/methods ; Skin Transplantation ; Surgical Flaps
Language	English
Publishing date	2018-03-18
Publishing country	Iran
Document type	Case Reports ; Journal Article
ZDB-ID	2251940-3
ISSN	1735-546X ; 1735-1308
ISSN (online)	1735-546X
ISSN	1735-1308
DOI	10.22037/uj.v0i0.4076
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Article ; Online: Prognostic and clinicopathologic value of ki-67 and profilin 1 immunohistochemical expression in primary pT1 urothelial bladder cancer.

Culpan, Meftun / Turan, Turgay / Ozkanli, Sidika Seyma / Zenginkinet, Tulay / Kazan, Ozgur / Ucar, Taha / Atis, Gokhan / Caskurlu, Turhan / Yildirim, Asif

Journal of cancer research and therapeutics

2021 Volume 17, Issue 2, Page(s) 434–442

Abstract: Purpose: To investigate the prognostic and clinicopathologic value of Ki-67 and profilin 1 immunohistochemical expression in primary pT1 papillary urothelial bladder cancer.: Materials and methods: This study included 88 male and 13 female pT1 ... ...

Abstract	Purpose: To investigate the prognostic and clinicopathologic value of Ki-67 and profilin 1 immunohistochemical expression in primary pT1 papillary urothelial bladder cancer. Materials and methods: This study included 88 male and 13 female pT1 primary bladder cancer patients. Demographic characteristics, tumor histological grade, tumor number, presence of concomitant carcinoma in situ, tumor size, and status of recurrence or progression were recorded for each patient. Expression of Ki-67 and profilin 1 was evaluated by immunohistochemical analysis of paraffin-embedded tumor tissues. The Pearson's Chi-square test was used for the analysis of qualitative data, and the Kaplan-Meier method and the log-rank test were used for the survival analysis. Results: In the mean follow-up period of 52 months, 52 (51.5%) patients experienced recurrence, 24 (23.8%) patients experienced progression, and 17 (16.8%) patients died from bladder cancer-related causes. Ki-67 expression was significantly associated with tumor histological grade (P = 0.001). In multivariate analysis, Ki-67 positivity had significantly worse outcome for recurrence (P = 0.006) and mortality (P = 0.022). Ki-67-positive (Ki-67 index ≥15%) patients had shorter recurrence-free (P = 0.003), progression-free (P = 0.002), and cancer-specific (P = 0.003) survival. However, no statistically significant relationship was found between profilin 1 expression and clinicopathologic features and prognosis. Conclusions: Ki-67 is a highly predictive biomarker for recurrence-free, progression-free, and cancer-specific survival in pT1 bladder cancer patients, in whom prediction of recurrence and progression are difficult. Ki-67 expression can be safely combined with other prognostic factors. However, in pT1 bladder cancer patients, no significant relationship was found between profilin 1 expression and tumor characteristics or prognostic parameters.
MeSH term(s)	Administration, Intravesical ; Adult ; Aged ; Aged, 80 and over ; BCG Vaccine/administration & dosage ; Carcinoma, Transitional Cell/diagnosis ; Carcinoma, Transitional Cell/mortality ; Carcinoma, Transitional Cell/pathology ; Carcinoma, Transitional Cell/therapy ; Chemotherapy, Adjuvant/methods ; Cystectomy ; Disease-Free Survival ; Female ; Follow-Up Studies ; Humans ; Immunohistochemistry ; Kaplan-Meier Estimate ; Ki-67 Antigen/analysis ; Ki-67 Antigen/metabolism ; Male ; Middle Aged ; Neoplasm Grading ; Neoplasm Recurrence, Local/epidemiology ; Neoplasm Recurrence, Local/prevention & control ; Neoplasm Staging ; Profilins/analysis ; Profilins/metabolism ; Prognosis ; Progression-Free Survival ; Retrospective Studies ; Urinary Bladder/pathology ; Urinary Bladder/surgery ; Urinary Bladder Neoplasms/diagnosis ; Urinary Bladder Neoplasms/mortality ; Urinary Bladder Neoplasms/pathology ; Urinary Bladder Neoplasms/therapy
Chemical Substances	BCG Vaccine ; Ki-67 Antigen ; MKI67 protein, human ; PFN1 protein, human ; Profilins
Language	English
Publishing date	2021-06-01
Publishing country	India
Document type	Journal Article
ZDB-ID	2187633-2
ISSN	1998-4138 ; 0973-1482
ISSN (online)	1998-4138
ISSN	0973-1482
DOI	10.4103/jcrt.JCRT_408_19
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Article: Thermal intravesical chemotherapy in adjuvant treatment of high risk non-muscle invasive bladder cancer.

Efiloğlu, Özgür / Bayrak, Ömer / Turan, Turgay / Kazan, Hüseyin Özgür / Çulpan, Meftun / Çakıcı, Mehmet Çağlar / Erturhan, Sakıp / Yıldırım, Asıf

Archivos espanoles de urologia

2021 Volume 74, Issue 9, Page(s) 875–882

Abstract: Objectives: To evaluate the oncological results of hyperthermic Mitomycin C (MMC) in adjuvant treatment of high-risk non-muscle invasive bladder cancer and to assess its side-effect profile.: Methods: Patients who were followed up in two reference ... ...

Title translation	Quimioterapia intravesical térmica como tratamiento adyuvante en pacientes de cáncer de vejiga alto riesgo no-musculoinvasivos.
Abstract	Objectives: To evaluate the oncological results of hyperthermic Mitomycin C (MMC) in adjuvant treatment of high-risk non-muscle invasive bladder cancer and to assess its side-effect profile. Methods: Patients who were followed up in two reference university hospitals due to high-risk non-muscle invasive bladder tumors were included in the study. High-risk patients according to the EAU non-muscle invasive bladder cancer guideline, patients who were rejected early cystectomy, patients who could not be treated with BCG due to a shortage, and patients for whom the cystectomy would be too risky due to their comorbidities were included in the study. All patients were followed up forat least 24 months with physical examination, cystoscopy, and urine cytology at 3-month intervals. Transurethral tumor resection was performed in all patients and a non-muscle invasive urothelial carcinoma was diagnosed pathologically. Hyperthermic MMC was administered with Synergo system SB-TS 101. Records were kept prospectively and evaluated retrospectively. Results: Fifty-eight high-risk group patients 18 (31%) of whom were at pTa stage and 40 (69%) at pT1 stage were included in the study. During a mean follow-up of 42 months, 34 (58%) patients had recurrence, while 5 (8%) patients progressed to muscle-invasive disease. Eleven (19%) of the patients under went radical cystectomy. The mean time to relapse was 10 months (3-34 months), and the mean time to progression was 41 months (6-87 months). Five-year overall survival, cancer-specific survival, progression-free survival, and relapse-free survival of the patients were 76%, 88%, 90% and 38%, respectively. Multifocality alone was found to be an independent risk factor (HR: 0.26; 95% Cl: 0.08-0.78; p=0.016) affecting recurrence. The observed side effects included tachycardia, cystitis, dysuria, macrohematuria, procedure-related pain, and allergic skin reactions. Treatment had to be discontinued in one patient due to a diffuse skin reaction. Conclusions: Thermal intravesical MMC therapyis a safe treatment and it could be effective treatment option in preventing disease progression in patients with high risk and non-muscle invasive bladder cancer with unsuccessful Bacillus Calmette-Guérin (BCG) or who could not be treated with BCG for other reasons.
MeSH term(s)	Adjuvants, Immunologic/therapeutic use ; Administration, Intravesical ; BCG Vaccine/adverse effects ; Carcinoma, Transitional Cell/drug therapy ; Chemotherapy, Adjuvant ; Humans ; Neoplasm Invasiveness ; Neoplasm Recurrence, Local ; Retrospective Studies ; Urinary Bladder Neoplasms/drug therapy
Chemical Substances	Adjuvants, Immunologic ; BCG Vaccine
Language	Spanish
Publishing date	2021-11-02
Publishing country	Spain
Document type	Journal Article
ZDB-ID	211673-x
ISSN	0004-0614
ISSN	0004-0614
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Article: Predictive preoperative factors for positive surgical margins in robotic radical prostatectomy in low-risk prostate cancer.

Turan, Turgay / Boylu, Uğur / Başataç, Cem / Gümüş, Eyüp

Turkish journal of urology

2015 Volume 39, Issue 2, Page(s) 69–73

Abstract: Objective: Positive surgical margins after radical prostatectomy for localized prostate cancer is a powerful predictor of PSA recurrence. Clinical stage, Gleason score and preoperative PSA are predictive factors for positive surgical margin after ... ...

Abstract	Objective: Positive surgical margins after radical prostatectomy for localized prostate cancer is a powerful predictor of PSA recurrence. Clinical stage, Gleason score and preoperative PSA are predictive factors for positive surgical margin after radical prostatectomy. In this study, we aimed to identify preoperative factors affecting surgical margin positivity in low-risk prostate cancer after robotic radical prostatectomy (RARP). Material and methods: Between 2008 and 2011 (<cT2b, PSA <10, Gleason <7), data from 112 patients with low-risk (<cT2b, PSA <10, Gleason <7), prostate cancer who had undergone RARP were examined prospectively. The effects of PSA, body mass index, surgery time after biopsy, percentage of positive cores, tumor length and prostate weight on positive surgical margin were evaluated. For statistical analyses, Mann-Whitney U, Pearson chi-square and logistic regression tests were used.<br />Results: It was observed that mean age and body mass index had no effect on positive surgical margins (p=0.2 and 0.6). According to univariate analysis, it was found that an elapsed time of less than six weeks from biopsy to surgery (p=0.07), tumor percentage of more than 5% in a biopsy specimen (p=0.003), a positive core percentage of more than 20% (p=0.045) and a prostate volume below 50 cc (p=0.037) increased the rate of positive surgical margins. Based on multivariate analysis, PSA levels above 5 ng/mL (OR: 8.006, p=0.012) and an elapsed time of less than 6 weeks between biopsy and surgery (OR: 10.814, p=0.029) increased the risk of positive surgical margins. Conclusion: In low-risk prostate cancer, a waiting time of less than six weeks between biopsy and surgery and PSA levels above 5 ng/mL are predictive of high surgical margin positivity after robotic radical prostatectomy.
Language	English
Publishing date	2015-06-01
Publishing country	Turkey
Document type	Journal Article
ISSN	2149-3235
ISSN	2149-3235
DOI	10.5152/tud.2013.020
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