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  1. Article ; Online: Design of Frustrated Lewis Pair Catalysts for Direct Hydrogenation of CO

    Das, Shubhajit / Turnell-Ritson, Roland C / Dyson, Paul J / Corminboeuf, Clémence

    Angewandte Chemie (International ed. in English)

    2022  Volume 61, Issue 46, Page(s) e202208987

    Abstract: Despite recent progress in the chemistry of frustrated Lewis pairs (FLPs), direct FLP-catalyzed hydrogenation of ... ...

    Abstract Despite recent progress in the chemistry of frustrated Lewis pairs (FLPs), direct FLP-catalyzed hydrogenation of CO
    Language English
    Publishing date 2022-10-17
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2011836-3
    ISSN 1521-3773 ; 1433-7851
    ISSN (online) 1521-3773
    ISSN 1433-7851
    DOI 10.1002/anie.202208987
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: The predictive capacity of in vitro preclinical models to evaluate drugs for the treatment of retinoblastoma.

    Sinenko, Irina L / Turnell-Ritson, Roland C / Munier, Francis L / Dyson, Paul J

    Experimental eye research

    2023  Volume 230, Page(s) 109447

    Abstract: Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used to treat retinoblastoma, all have been repurposed from drugs developed for other conditions. In order to find drugs or drug combinations better suited to the ... ...

    Abstract Retinoblastoma is a rare childhood cancer of the eye. Of the small number of drugs are used to treat retinoblastoma, all have been repurposed from drugs developed for other conditions. In order to find drugs or drug combinations better suited to the improved treatment of retinoblastoma, reliable predictive models are required, which facilitate the challenging transition from in vitro studies to clinical trials. In this review, the research performed to date on the development of 2D and 3D in vitro models for retinoblastoma is presented. Most of this research was undertaken with a view to better biological understanding of retinoblastoma, and we discuss the potential for these models to be applied to drug screening. Future research directions for streamlined drug discovery are considered and evaluated, and many promising avenues identified.
    MeSH term(s) Humans ; Child ; Retinoblastoma/drug therapy ; Drug Evaluation, Preclinical ; Retinal Neoplasms/drug therapy
    Language English
    Publishing date 2023-03-20
    Publishing country England
    Document type Journal Article ; Review ; Research Support, Non-U.S. Gov't
    ZDB-ID 80122-7
    ISSN 1096-0007 ; 0014-4835
    ISSN (online) 1096-0007
    ISSN 0014-4835
    DOI 10.1016/j.exer.2023.109447
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article ; Online: Controlling the selectivity of the hydrogenolysis of polyamides catalysed by ceria-supported metal nanoparticles.

    Wu, XinBang / Lee, Wei-Tse / Turnell-Ritson, Roland C / Delannoi, Pauline C L / Lin, Kun-Han / Dyson, Paul J

    Nature communications

    2023  Volume 14, Issue 1, Page(s) 6524

    Abstract: Catalytic hydrogenolysis is a promising approach to transform waste plastic into valuable chemicals. However, the transformation of N-containing polymers, such as polyamides (i.e. nylon), remains under-investigated, particularly by heterogeneous ... ...

    Abstract Catalytic hydrogenolysis is a promising approach to transform waste plastic into valuable chemicals. However, the transformation of N-containing polymers, such as polyamides (i.e. nylon), remains under-investigated, particularly by heterogeneous catalysis. Here, we demonstrate the hydrogenolysis of various polyamides catalysed by platinum-group metal nanoparticles supported on CeO
    Language English
    Publishing date 2023-10-16
    Publishing country England
    Document type Journal Article
    ZDB-ID 2553671-0
    ISSN 2041-1723 ; 2041-1723
    ISSN (online) 2041-1723
    ISSN 2041-1723
    DOI 10.1038/s41467-023-42246-x
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  4. Article ; Online: Influence of an Organic Salt-Based Stabilizing Additive on Charge Carrier Dynamics in Triple Cation Perovskite Solar Cells.

    Dörflinger, Patrick / Ding, Yong / Schmid, Valentin / Armer, Melina / Turnell-Ritson, Roland C / Ding, Bin / Dyson, Paul J / Nazeeruddin, Mohammad Khaja / Dyakonov, Vladimir

    Advanced science (Weinheim, Baden-Wurttemberg, Germany)

    2023  Volume 10, Issue 34, Page(s) e2304502

    Abstract: Besides further improvement in the power conversion efficiency (PCE) of perovskite solar cells (PSC), their long-term stability must also be ensured. Additives such as organic cations with halide counter anions are considered promising candidates to ... ...

    Abstract Besides further improvement in the power conversion efficiency (PCE) of perovskite solar cells (PSC), their long-term stability must also be ensured. Additives such as organic cations with halide counter anions are considered promising candidates to address this challenge, conferring both higher performance and increased stability to perovskite-based devices. Here, a stabilizing additive (N,N-dimethylmethyleneiminium chloride, [Dmmim]Cl) is identified, and its effect on charge carrier mobility and lifetime under thermal stress in triple cation perovskite (Cs
    Language English
    Publishing date 2023-10-09
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 2808093-2
    ISSN 2198-3844 ; 2198-3844
    ISSN (online) 2198-3844
    ISSN 2198-3844
    DOI 10.1002/advs.202304502
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  5. Article: Establishing the Role of Triflate Anions in H

    Sapsford, Joshua S / Csókás, Dániel / Scott, Daniel J / Turnell-Ritson, Roland C / Piascik, Adam D / Pápai, Imre / Ashley, Andrew E

    ACS catalysis

    2020  Volume 10, Issue 14, Page(s) 7573–7583

    Abstract: Cationic Lewis acids (LAs) are gaining interest as targets for frustrated Lewis pair (FLP)-mediated catalysis. Unlike neutral boranes, which are the most prevalent LAs for FLP hydrogenations, the Lewis acidity of cations can be tuned through modulation ... ...

    Abstract Cationic Lewis acids (LAs) are gaining interest as targets for frustrated Lewis pair (FLP)-mediated catalysis. Unlike neutral boranes, which are the most prevalent LAs for FLP hydrogenations, the Lewis acidity of cations can be tuned through modulation of the counteranion; however, detailed studies on such anion effects are currently lacking in the literature. Herein, we present experimental and computational studies which probe the mechanism of H
    Language English
    Publishing date 2020-06-08
    Publishing country United States
    Document type Journal Article
    ISSN 2155-5435
    ISSN 2155-5435
    DOI 10.1021/acscatal.0c02023
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  6. Article: Base-induced reversible H

    Turnell-Ritson, Roland C / Sapsford, Joshua S / Cooper, Robert T / Lee, Stella S / Földes, Tamás / Hunt, Patricia A / Pápai, Imre / Ashley, Andrew E

    Chemical science

    2018  Volume 9, Issue 46, Page(s) 8716–8722

    Abstract: A range of amines catalyse the oxidative addition (OA) of ... ...

    Abstract A range of amines catalyse the oxidative addition (OA) of H
    Language English
    Publishing date 2018-09-18
    Publishing country England
    Document type Journal Article
    ZDB-ID 2559110-1
    ISSN 2041-6539 ; 2041-6520
    ISSN (online) 2041-6539
    ISSN 2041-6520
    DOI 10.1039/c8sc03110j
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  7. Article: Hydrogen activation using a novel tribenzyltin Lewis acid.

    Cooper, Robert T / Sapsford, Joshua S / Turnell-Ritson, Roland C / Hyon, Dong-Hun / White, Andrew J P / Ashley, Andrew E

    Philosophical transactions. Series A, Mathematical, physical, and engineering sciences

    2017  Volume 375, Issue 2101

    Abstract: Over the last decade there has been an explosion in the reactivity and applications of frustrated Lewis pair (FLP) chemistry. Despite this, the Lewis acids (LAs) in these transformations are often boranes, with ... ...

    Abstract Over the last decade there has been an explosion in the reactivity and applications of frustrated Lewis pair (FLP) chemistry. Despite this, the Lewis acids (LAs) in these transformations are often boranes, with heavier
    Language English
    Publishing date 2017-05-31
    Publishing country England
    Document type Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 208381-4
    ISSN 1471-2962 ; 1364-503X ; 0080-4614 ; 0264-3820 ; 0264-3952
    ISSN (online) 1471-2962
    ISSN 1364-503X ; 0080-4614 ; 0264-3820 ; 0264-3952
    DOI 10.1098/rsta.2017.0008
    Database MEDical Literature Analysis and Retrieval System OnLINE

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