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  1. Article ; Online: Modifying gastruloids to dissect mechanisms of tissue-specific induction.

    Turner, David A / Nichols, Jennifer

    Current opinion in genetics & development

    2023  Volume 83, Page(s) 102130

    Abstract: How functional organisms arise from a single cell is a fundamental question in biology with direct relevance to understanding developmental defects and diseases. Dissecting developmental processes provides the basic, critical framework for understanding ... ...

    Abstract How functional organisms arise from a single cell is a fundamental question in biology with direct relevance to understanding developmental defects and diseases. Dissecting developmental processes provides the basic, critical framework for understanding disease progression and treatment. Bottom-up approaches to recapitulate formation of various components of the embryo have been effective to probe symmetry-breaking, self-organisation, tissue patterning and morphogenesis. However, these studies have been mostly concerned with axial patterning, which is essentially longitudinal. Can these models generate the appendicular axes? If so, how far can self-organisation take these? Will experimentally induced organisers be required? This short review explores these questions, highlighting how minimal models are essential for understanding patterning and morphogenetic processes.
    MeSH term(s) Body Patterning/genetics ; Morphogenesis/genetics ; Embryo, Mammalian
    Language English
    Publishing date 2023-10-26
    Publishing country England
    Document type Journal Article ; Review
    ZDB-ID 1077312-5
    ISSN 1879-0380 ; 0959-437X
    ISSN (online) 1879-0380
    ISSN 0959-437X
    DOI 10.1016/j.gde.2023.102130
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  2. Article ; Online: Entrustable Professional Activities: Reflecting on Where We Are to Define a Path for the Next Decade.

    Schumacher, Daniel J / Turner, David A

    Academic medicine : journal of the Association of American Medical Colleges

    2021  Volume 96, Issue 7S, Page(s) S1–S5

    MeSH term(s) Clinical Competence ; Competency-Based Education ; Education, Medical ; Humans ; Implementation Science
    Language English
    Publishing date 2021-06-24
    Publishing country United States
    Document type Introductory Journal Article ; Research Support, Non-U.S. Gov't
    ZDB-ID 96192-9
    ISSN 1938-808X ; 1040-2446
    ISSN (online) 1938-808X
    ISSN 1040-2446
    DOI 10.1097/ACM.0000000000004097
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  3. Article: Can a Robot Bring Your Life Back? A Systematic Review for Robotics in Rehabilitation.

    Chew, Esyin / Turner, David A

    Advances in experimental medicine and biology

    2020  Volume 1170, Page(s) 1–35

    Abstract: Stroke is a leading cause of disability in the world and the use of robots in rehabilitation has become increasingly common. The Fourth Industrial Revolutions has created a novel and wide range of options for the involvement of computer-guided and ... ...

    Abstract Stroke is a leading cause of disability in the world and the use of robots in rehabilitation has become increasingly common. The Fourth Industrial Revolutions has created a novel and wide range of options for the involvement of computer-guided and artificially intelligent machines to be used in rehabilitation. In this chapter we critically review some of the literature on the use of robots in rehabilitation, and emphasize the diversity of approaches in this burgeoning field. We argue that there is a need to consolidate interdisciplinary evidence on robotics and rehabilitation in a systematic way, as the alternative is to have a literature that continues to grow, following the interests of various specialists, but without offering a synoptic assessment of what is available to medical specialists and patients. A literature review using Scopus and Web of Science, coupled with the Briggs Institute's Critical Appraisal Tool: Checklist for Case Reports was conducted. The two databases were systematically searched using inter-disciplinary keywords in Feb 2019. An initial search of the databases produced 9894 articles. After rigorous reviews, 35 articles were screened and selected for further interpretation. We examined the current studies on the efficiency and effectiveness of the robot interventions and produced a taxonomy of the review. An original finding of the current robotics in rehabilitation landscaping are critical presented with recommendations and concluding remarks concerning interdisciplinary impact.
    MeSH term(s) Humans ; Robotics/instrumentation ; Stroke ; Stroke Rehabilitation/instrumentation ; Stroke Rehabilitation/methods
    Language English
    Publishing date 2020-02-17
    Publishing country United States
    Document type Journal Article ; Systematic Review
    ISSN 2214-8019 ; 0065-2598
    ISSN (online) 2214-8019
    ISSN 0065-2598
    DOI 10.1007/978-3-030-24230-5_1
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  4. Article: An Online Curriculum in the PICU-Do You Have Plans Tonight?

    Schwartz, Stephanie P / Turner, David A

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2020  Volume 21, Issue 11, Page(s) 1005–1006

    MeSH term(s) Child ; Critical Care ; Curriculum ; Humans ; Intensive Care Units, Pediatric ; Rotation
    Language English
    Publishing date 2020-11-02
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000002530
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    Zs.MO 472: Show issues

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  5. Article ; Online: Is 24/7 In-Hospital Coverage Mutually Beneficial for Patients and Intensivists?

    Rehder, Kyle J / Turner, David A

    Critical care medicine

    2019  Volume 47, Issue 7, Page(s) 999

    MeSH term(s) Humans ; Intensive Care Units ; Physicians ; Workforce
    Language English
    Publishing date 2019-08-15
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 197890-1
    ISSN 1530-0293 ; 0090-3493
    ISSN (online) 1530-0293
    ISSN 0090-3493
    DOI 10.1097/CCM.0000000000003792
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  6. Article: Can We Finally Agree: How We Round Really Matters?

    Rehder, Kyle J / Reyes Alvarado, Edith / Turner, David A

    Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies

    2021  Volume 22, Issue 4, Page(s) 432–434

    MeSH term(s) Delphi Technique ; Goals ; Humans ; Models, Psychological ; Teaching Rounds
    Language English
    Publishing date 2021-03-31
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 2052349-X
    ISSN 1947-3893 ; 1529-7535
    ISSN (online) 1947-3893
    ISSN 1529-7535
    DOI 10.1097/PCC.0000000000002642
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  7. Article ; Online: Analysis of fellowship program director opinions of entrustable professional activities in adolescent medicine fellowship.

    Cifra, Nicole / Pitts, Sarah / Mink, Richard / Schwartz, Alan / Herman, Bruce / Turner, David A / Yussman, Susan

    International journal of adolescent medicine and health

    2024  

    Abstract: Objectives: This study aimed to explore the minimum entrustable professional activity (EPA) supervision levels at which pediatric fellowship program directors (FPDs) would be willing to graduate fellows and the levels deemed necessary for safe and ... ...

    Abstract Objectives: This study aimed to explore the minimum entrustable professional activity (EPA) supervision levels at which pediatric fellowship program directors (FPDs) would be willing to graduate fellows and the levels deemed necessary for safe and effective practice for each of the common pediatric subspecialty and the four adolescent medicine-specific EPAs.
    Methods: This cross-sectional study utilized survey data from pediatric FPDs in 2017. FPDs indicated the minimum level of supervision (LOS) for fellows at graduation and for safe and effective practice.
    Results: 82 percent (23/28) of adolescent medicine FPDs completed the survey. For each EPA, there were differences (p<0.05) between LOS expected for graduation and for safe and effective practice. There was also variability in the level at which FPDs would graduate fellows.
    Conclusions: This study summarizes pediatric FPD opinions regarding the minimum levels of supervision required for fellows at the time of graduation as well as the levels deemed necessary for safe and effective practice. The difference between the minimum LOS at which FPDs would graduate a fellow and that deemed appropriate for safe and effective practice, along with variability in minimum LOS for graduation, highlight the need for clearer standards for fellowship graduation as well as more structured early career support for ongoing learning. These data highlight variability in FPD opinion regarding such expectations and both the need to better define desired training outcomes and potential need for post-graduation supervision in clinical practice.
    Language English
    Publishing date 2024-03-25
    Publishing country Germany
    Document type Journal Article
    ZDB-ID 639287-8
    ISSN 2191-0278 ; 0334-0139
    ISSN (online) 2191-0278
    ISSN 0334-0139
    DOI 10.1515/ijamh-2023-0154
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    Zs.B 3178: Show issues Location:
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  8. Article ; Online: A realist synthesis of prospective entrustment decision making by entrustment or clinical competency committees.

    Schumacher, Daniel J / Michelson, Catherine / Winn, Ariel S / Turner, David A / Martini, Abigail / Kinnear, Benjamin

    Medical education

    2023  

    Abstract: Introduction: The real-world mechanisms underlying prospective entrustment decision making (PEDM) by entrustment or clinical competency committees (E/CCCs) are poorly understood. To advance understanding in this area, the authors conducted a realist ... ...

    Abstract Introduction: The real-world mechanisms underlying prospective entrustment decision making (PEDM) by entrustment or clinical competency committees (E/CCCs) are poorly understood. To advance understanding in this area, the authors conducted a realist synthesis of the published literature to address the following research question: In E/CCC efforts to make defensible prospective entrustment decisions (PEDs), what works, for whom, under what circumstances and why?
    Methods: Realist work seeks to understand the contexts (C), mechanisms (M) and outcomes (O) that explain how and why things work (or do not). In the authors' study, contexts included individual E/CCC members, E/CCC structures and processes, and training programmes. The outcome (i.e. desired outcome) was a PED. Mechanisms were a substantial focus of the analysis and informed the core findings. To define a final corpus of 52 included papers, the authors searched four databases, screened all results from those searches and performed a full-text review of a subset of screened papers. Data extraction focused on developing context-mechanism-outcome configurations from the papers, which were used to create a theory for how PEDM leads to PEDs.
    Results: PEDM is often driven by default (non-deliberate) decision making rather than a deliberate process of deciding whether a trainee should be entrusted or not. When defaulting, some E/CCCs find red flags that sometimes lead to being more deliberate with decision making. E/CCCs that seek to be deliberate describe PEDM that can be effortful (when data are insufficient or incongruent) or effortless (when data are robust and tell a congruent story about a trainee). Both information about trainee trustworthiness and the sufficiency of data about trainee performance influence PEDM. Several moderators influence what is considered to be sufficient data, how trustworthiness data are viewed and how PEDM is carried out. These include perceived consequences and associated risks, E/CCC member trust propensity, E/CCC member personal knowledge of and experience with trainees and E/CCC structures and processes.
    Discussion: PEDM is rarely deliberate but should be. Data about trainee trustworthiness are foundational to making PEDs. Bias, equity and fairness are nearly absent from the papers in this synthesis, and future efforts must seek to advance understanding and practice regarding the roles of bias, equity and fairness in PEDM.
    Language English
    Publishing date 2023-12-13
    Publishing country England
    Document type Journal Article
    ZDB-ID 195274-2
    ISSN 1365-2923 ; 0308-0110
    ISSN (online) 1365-2923
    ISSN 0308-0110
    DOI 10.1111/medu.15296
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  9. Article ; Online: Actual Versus Ideal Body Weight: The Devil Is in the Details.

    Rehder, Kyle J / Turner, David A

    Respiratory care

    2018  Volume 63, Issue 9, Page(s) 1189–1190

    MeSH term(s) Body Weight ; Humans ; Ideal Body Weight
    Language English
    Publishing date 2018-08-30
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.06534
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  10. Article ; Online: Extracorporeal Membrane Oxygenation Does Not Necessarily Mean Easier Breathing.

    Rehder, Kyle J / Davies, John D / Turner, David A

    Respiratory care

    2020  Volume 65, Issue 7, Page(s) 1057–1058

    MeSH term(s) Carbon Dioxide ; Extracorporeal Membrane Oxygenation ; Humans ; Respiration ; Respiratory Distress Syndrome, Adult ; Risk Factors
    Chemical Substances Carbon Dioxide (142M471B3J)
    Language English
    Publishing date 2020-06-30
    Publishing country United States
    Document type Editorial ; Comment
    ZDB-ID 603252-7
    ISSN 1943-3654 ; 0098-9142 ; 0020-1324
    ISSN (online) 1943-3654
    ISSN 0098-9142 ; 0020-1324
    DOI 10.4187/respcare.08085
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