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  1. AU="Tuttle, Marcelle L"
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  1. Article ; Online: Coronary Artery Bypass Grafting Versus Percutaneous Coronary Intervention in Patients Receiving Dialysis: Is CABG Worth the Risk?

    Tuttle, Marcelle L / Weiner, Daniel E

    Kidney medicine

    2023  Volume 6, Issue 2, Page(s) 100787

    Language English
    Publishing date 2023-12-22
    Publishing country United States
    Document type Editorial
    ISSN 2590-0595
    ISSN (online) 2590-0595
    DOI 10.1016/j.xkme.2023.100787
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article ; Online: Epidemiology and Management of Patients With Kidney Disease and Heart Failure With Preserved Ejection Fraction.

    Tuttle, Marcelle L / Fang, James C / Sarnak, Mark J / McCallum, Wendy

    Seminars in nephrology

    2024  , Page(s) 151516

    Abstract: Heart failure with preserved ejection fraction (HFpEF) comprises approximately one-half of all diagnoses of heart failure. There is significant overlap of this clinical syndrome with chronic kidney disease (CKD), with many shared comorbid conditions. The ...

    Abstract Heart failure with preserved ejection fraction (HFpEF) comprises approximately one-half of all diagnoses of heart failure. There is significant overlap of this clinical syndrome with chronic kidney disease (CKD), with many shared comorbid conditions. The presence of CKD in patients with HFpEF is one of the most powerful risk factors for adverse clinical outcomes, including death and heart failure hospitalization. The pathophysiology linking HFpEF and CKD remains unclear, but it is postulated to consist of numerous bidirectional pathways, including endothelial dysfunction, inflammation, obesity, insulin resistance, and impaired sodium handling. The diagnosis of HFpEF requires certain criteria to be satisfied, including signs and symptoms consistent with volume overload caused by structural or functional cardiac abnormalities and evidence of increased cardiac filling pressures. There are numerous overlapping metabolic clinical syndromes in patients with HFpEF and CKD that can serve as targets for intervention. With an increasing number of therapies available for HFpEF and CKD as well as for obesity and diabetes, improved recognition and diagnosis are paramount for appropriate management and improved clinical outcomes in patients with both HFpEF and CKD.
    Language English
    Publishing date 2024-05-03
    Publishing country United States
    Document type Journal Article ; Review
    ZDB-ID 604652-6
    ISSN 1558-4488 ; 0270-9295
    ISSN (online) 1558-4488
    ISSN 0270-9295
    DOI 10.1016/j.semnephrol.2024.151516
    Database MEDical Literature Analysis and Retrieval System OnLINE

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