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Article ; Online: From Lifeguard to Lighthouse.

Tyler, Matthew J

2021 Volume 24, Issue 5, Page(s) 792

Language	English
Publishing date	2021-05-04
Publishing country	United States
Document type	Journal Article
ZDB-ID	1427361-5
ISSN	1557-7740 ; 1096-6218
ISSN (online)	1557-7740
ISSN	1096-6218
DOI	10.1089/jpm.2020.0662
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Article ; Online: What Will Hospice Do When She Gets Sicker?

Tyler, Matthew J

Journal of palliative medicine

2019 Volume 22, Issue 11, Page(s) 1476

MeSH term(s)	Hospice Care ; Humans ; Palliative Care ; Severity of Illness Index ; Terminally Ill
Language	English
Publishing date	2019-10-28
Publishing country	United States
Document type	Journal Article ; Personal Narrative
ZDB-ID	1427361-5
ISSN	1557-7740 ; 1096-6218
ISSN (online)	1557-7740
ISSN	1096-6218
DOI	10.1089/jpm.2019.0206
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Article ; Online: Characterizing Trends in Diagnosis and Management of Sinusitis in a Large Health Care System: From Primary Care to Otolaryngology.

Hornung, Christopher M / Ganti, Ashwin / Lunos, Scott / Tyler, Matthew A

The Annals of otology, rhinology, and laryngology

2024 Volume 133, Issue 5, Page(s) 476–484

Abstract: Objectives: Variations in management of sinusitis in primary care settings can be associated with inappropriate antibiotic prescriptions and delays in treatment. The objective of this study was to identify patient and provider characteristics associated ...

Abstract	Objectives: Variations in management of sinusitis in primary care settings can be associated with inappropriate antibiotic prescriptions and delays in treatment. The objective of this study was to identify patient and provider characteristics associated with possible inaccurate diagnosis and management of sinusitis. Methods: We performed a cross-sectional retrospective analysis using an established regional healthcare database of patients who received a diagnosis of sinusitis between 2011 and 2022 from a non-otolaryngologist provider. Patient's comorbidities, insurance status, chronicity of sinusitis, and prescriptions were included. We noted if patients were referred to an otolaryngology practice and if they received a diagnosis of sinusitis from an otolaryngologist. Results: We analyzed 99 581 unique patients and 168 137 unique encounters. The mean age was 41.5 (±20.4 years) and 35.7% were male. Most patients had private insurance (88.5%), acute sinusitis (81.2%), and were seen at a primary care office (97.8%). Approximately 30% of patients were referred to an otolaryngology practice for sinusitis. Of referred patients, 50.6% did not receive a diagnosis of sinusitis from an otolaryngology practice. Patients without a sinusitis diagnosis by an otolaryngology practice received significantly more mean courses of antibiotics (5.04 vs 2.39, Conclusions: Over half of the patients referred to an otolaryngology practice from primary care for sinusitis did not receive a diagnosis of sinusitis from an otolaryngology practice. Further research should investigate implications for increased healthcare costs and inappropriate prescription trends associated with the management of sinusitis.
MeSH term(s)	Humans ; Male ; Adult ; Female ; Cross-Sectional Studies ; Retrospective Studies ; Practice Patterns, Physicians' ; Sinusitis/therapy ; Sinusitis/drug therapy ; Otolaryngology ; Primary Health Care ; Anti-Bacterial Agents/therapeutic use
Chemical Substances	Anti-Bacterial Agents
Language	English
Publishing date	2024-02-12
Publishing country	United States
Document type	Journal Article
ZDB-ID	120642-4
ISSN	1943-572X ; 0003-4894
ISSN (online)	1943-572X
ISSN	0003-4894
DOI	10.1177/00034894241230365
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Article ; Online: A Consistent Endoscopic Landmark to Identify the Anterior Ethmoidal Artery.

Mundy, David C / Yan, Carol H / Tyler, Matthew A / Patel, Zara M

The Laryngoscope

2023 Volume 134, Issue 3, Page(s) 1096–1099

Abstract: Objective: The anterior ethmoidal artery (AEA) is an important structure to identify during endoscopic sinus surgery. Although identification on imaging is easily taught, a consistent endoscopic landmark for the AEA, independent of anatomic ethmoid cell ...

Abstract	Objective: The anterior ethmoidal artery (AEA) is an important structure to identify during endoscopic sinus surgery. Although identification on imaging is easily taught, a consistent endoscopic landmark for the AEA, independent of anatomic ethmoid cell variation, is lacking, leaving many surgeons unclear about the exact location without dependence on navigation. Here, we describe a consistent endoscopic landmark, regardless of anatomical ethmoid variation. Methods: We prospectively enrolled adult patients undergoing endoscopic surgery involving frontal and ethmoid sinuses in this observational study. The AEA landmark was defined simply as the septation or ridge one step back along the ethmoid skull base from the posterior table of the frontal sinus. The gold standard to calculate the sensitivity of our endoscopic landmark was an image-navigation system, registered to within 1.5 mm accuracy, locating the AEA within three planes. Both endoscopic and computerized tomography (CT) images of the pointer at the landmark were taken simultaneously. The concordance of endoscopic to navigation images was independently assessed by three blinded rhinologists. Results: Forty patients were included in our study with 73 sides analyzed. Diagnoses included chronic rhinosinusitis without polyps (52.5%), with polyps (22.5%), recurrent acute sinusitis (15%), sinonasal tumors (7.5%), and odontogenic sinusitis (2.5%). The AEA was accurately identified using our endoscopic landmark in 97.3% of the cases (71/73). Of the two cases in which the AEA was not found within the landmark, the artery was located ≤1 mm posteriorly. Conclusion: We describe a consistent endoscopic landmark to identify the AEA, conserved across various clinical diagnoses and anatomic variations in sinus structure. Level of evidence: 3 Laryngoscope, 134:1096-1099, 2024.
MeSH term(s)	Adult ; Humans ; Skull Base/surgery ; Arteries/surgery ; Ethmoid Bone ; Ethmoid Sinus/diagnostic imaging ; Ethmoid Sinus/surgery ; Ethmoid Sinus/blood supply ; Endoscopy/methods ; Sinusitis
Language	English
Publishing date	2023-08-14
Publishing country	United States
Document type	Observational Study ; Journal Article
ZDB-ID	80180-x
ISSN	1531-4995 ; 0023-852X
ISSN (online)	1531-4995
ISSN	0023-852X
DOI	10.1002/lary.30963
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Article ; Online: Inflammatory Sinonasal Polyposis-Causing Globe Perforation-With Response to Dupilumab Therapy.

Kamboj, Alisha / McClelland, Collin M / Tyler, Matthew A / Mokhtarzadeh, Ali

Ophthalmic plastic and reconstructive surgery

2023 Volume 40, Issue 1, Page(s) e32

MeSH term(s)	Humans ; Inflammation ; Antibodies, Monoclonal, Humanized/therapeutic use ; Nasal Polyps/complications ; Nasal Polyps/diagnosis ; Nasal Polyps/drug therapy ; Chronic Disease
Chemical Substances	dupilumab (420K487FSG) ; Antibodies, Monoclonal, Humanized
Language	English
Publishing date	2023-06-23
Publishing country	United States
Document type	Journal Article
ZDB-ID	632830-1
ISSN	1537-2677 ; 0740-9303
ISSN (online)	1537-2677
ISSN	0740-9303
DOI	10.1097/IOP.0000000000002414
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Article ; Online: Chronic Rhinosinusitis After Maxillary Advancement Orthognathic Surgery.

Ibrahim, Nour / Hwang, Peter H / Jitaroon, Kawinyarat / Tyler, Matthew A

The Annals of otology, rhinology, and laryngology

2023 Volume 133, Issue 3, Page(s) 261–267

Abstract: Introduction: Maxillomandibular advancement (MMA) remains an effective procedure for the management of obstructive sleep apnea (OSA). Maxillary advancement may lead to anatomical changes that impair paranasal sinus drainage, leading to chronic sinus ... ...

Abstract	Introduction: Maxillomandibular advancement (MMA) remains an effective procedure for the management of obstructive sleep apnea (OSA). Maxillary advancement may lead to anatomical changes that impair paranasal sinus drainage, leading to chronic sinus inflammation. The aim of this study was to describe the clinical features and outcomes of patients suffering from chronic rhinosinusitis (CRS) following MMA. Methods: This is a retrospective case series study. Our study included subjects diagnosed with CRS following MMA from January 1992 to October 2018 at Stanford Hospital. We screened 730 patients undergoing MMA and identified a total of 57 with CRS after MMA. A descriptive analysis was performed using clinical data including patient demographics, comorbidities, prior surgical history, physical exam manifestations, CT findings, and quality of life outcomes (SNOT-22). Results: Out of 730 patients undergoing MMA, 57(7.8%) were found to have CRS after orthognathic surgery. Presenting symptoms included facial pain (92.5%), nasal drainage (75%), nasal obstruction (67.5%), and hyposmia (20%). Endoscopic examination revealed recirculation (30.5%), purulent discharge (27.7%), polypoid changes (22.2%), and scarring (13.8%). Preoperative CT prior to undergoing endoscopic sinus surgery (ESS) demonstrated mucosal thickening in maxillary (64.2%), anterior ethmoid (39.2%), frontal (14.2%), posterior ethmoid (10.7%), sphenoid sinus (14.2%), and ostiomeatal complex (55.3%). Average Lund-Mackay score was 5.5(±3.8). Additional CT findings included secondary ostium in the inferior meatus (42.8%). Forty patients (70.1%) underwent ESS at a mean of 4.6 years after MMA. Patients undergoing ESS experienced significant improvement in SNOT-22 scores at 12-months post-surgery ( Conclusion: Patients undergoing maxillary advancement surgery are at risk of developing CRS postoperatively and should be advised of the risk of CRS associated with this procedure. Surgical treatment can be an option for medically refractory CRS related to MMA surgery.
MeSH term(s)	Humans ; Orthognathic Surgery ; Retrospective Studies ; Quality of Life ; Rhinosinusitis ; Sinusitis/diagnosis ; Sinusitis/surgery ; Chronic Disease ; Endoscopy/adverse effects ; Endoscopy/methods ; Inflammation ; Rhinitis/diagnosis ; Rhinitis/surgery ; Treatment Outcome
Language	English
Publishing date	2023-10-06
Publishing country	United States
Document type	Journal Article
ZDB-ID	120642-4
ISSN	1943-572X ; 0003-4894
ISSN (online)	1943-572X
ISSN	0003-4894
DOI	10.1177/00034894231204654
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Article ; Online: Current Concepts in the Management of Allergic Fungal Rhinosinusitis.

Tyler, Matthew A / Luong, Amber U

Immunology and allergy clinics of North America

2020 Volume 40, Issue 2, Page(s) 345–359

Abstract: Allergic fungal rhinosinusitis (AFRS) represents a subtype of chronic rhinosinusitis with nasal polyposis that exhibits a unique, often striking clinical presentation. Since its initial description more than a quarter century ago, a more sophisticated ... ...

Abstract	Allergic fungal rhinosinusitis (AFRS) represents a subtype of chronic rhinosinusitis with nasal polyposis that exhibits a unique, often striking clinical presentation. Since its initial description more than a quarter century ago, a more sophisticated understanding of the pathophysiology of AFRS has been achieved and significant advancements in improving clinical outcomes made. This review focuses on the latest developments involving the pathophysiology and clinical management of this fascinating disease.
MeSH term(s)	Chronic Disease ; Eosinophils/immunology ; Humans ; Mycoses/diagnosis ; Mycoses/therapy ; Nasal Polyps/diagnosis ; Nasal Polyps/therapy ; Rhinitis, Allergic/diagnosis ; Rhinitis, Allergic/therapy ; Sinusitis/diagnosis ; Sinusitis/therapy ; Th2 Cells/immunology
Language	English
Publishing date	2020-01-29
Publishing country	United States
Document type	Journal Article ; Review
ZDB-ID	92606-1
ISSN	1557-8607 ; 0889-8561
ISSN (online)	1557-8607
ISSN	0889-8561
DOI	10.1016/j.iac.2019.12.001
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Article ; Online: Prognostic Factors and Treatment Impact on Overall Survival in Adult Craniopharyngioma.

Awad, Matthew / Butterfield, John T / Dhawan, Sanjay / Tyler, Matthew A / Venteicher, Andrew S

World neurosurgery

2023 Volume 173, Page(s) e132–e139

Abstract: Objective: To examine the demographics, tumor characteristics, treatments, and clinical outcomes of a large adult craniopharyngioma population.: Methods: The 2004-2018 National Cancer Database was queried to investigate adult patients with ... ...

Abstract	Objective: To examine the demographics, tumor characteristics, treatments, and clinical outcomes of a large adult craniopharyngioma population. Methods: The 2004-2018 National Cancer Database was queried to investigate adult patients with craniopharyngioma. Univariable and multivariable Cox hazard ratio analysis was conducted to analyze the overall survival (OS) impact of demographic and clinical variables. Results: A total of 666 adult patients with craniopharyngioma were identified with a mean age of 51 years (standard deviation 16 years). On multivariable analysis, independent of demographic and clinical variables, increased age, uninsured status, Medicaid, Medicare, Charlson-Deyo Comorbidity Index of 2, and tumor size greater than 40 mm were independently associated with worse OS. There was no significant difference in survival between histologic subtypes. Gross total resection (GTR) (hazard ratio [HR] 0.602, 95% confidence interval [CI] 0.384-0.942, P = 0.026) and subtotal resection (STR) with adjuvant radiotherapy (HR 0.316, 95% CI 0.140-0.710, P = 0.005) were independently associated with improved OS. GTR with radiotherapy trended towards improved OS (HR 0.601, 95% CI 0.334-1.083, P =0.090), but STR alone and radiotherapy alone demonstrated no significant difference in survival compared with no treatment on multivariable analysis. Kaplan-Meier survival models demonstrated improved survival with GTR, GTR + radiation therapy, and STR + radiation therapy. Patients undergoing endoscopic resection had significantly lower GTR rates and greater rates of adjuvant radiotherapy compared with open approaches but no difference in OS. Conclusion: Adult patients with craniopharyngioma who underwent GTR or STR with adjuvant radiotherapy had significantly improved overall survival. Endoscopic approaches had lower rates of GTR but no difference in OS.
MeSH term(s)	Adult ; Humans ; Aged ; United States/epidemiology ; Middle Aged ; Craniopharyngioma/surgery ; Craniopharyngioma/pathology ; Treatment Outcome ; Prognosis ; Pituitary Neoplasms/surgery ; Pituitary Neoplasms/pathology ; Medicare ; Radiotherapy, Adjuvant ; Retrospective Studies
Language	English
Publishing date	2023-02-10
Publishing country	United States
Document type	Journal Article
ZDB-ID	2534351-8
ISSN	1878-8769 ; 1878-8750
ISSN (online)	1878-8769
ISSN	1878-8750
DOI	10.1016/j.wneu.2023.02.020
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Article ; Online: Reply to Kalmoe and Mason: The pitfalls of using surveys to measure low-prevalence attitudes and behavior.

Westwood, Sean J / Grimmer, Justin / Tyler, Matthew / Nall, Clayton

Proceedings of the National Academy of Sciences of the United States of America

2022 Volume 119, Issue 32, Page(s) e2207584119

MeSH term(s)	Attitude ; Humans ; Prevalence ; Surveys and Questionnaires
Language	English
Publishing date	2022-07-25
Publishing country	United States
Document type	Letter ; Comment
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2207584119
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Article ; Online: Current research overstates American support for political violence.

Westwood, Sean J / Grimmer, Justin / Tyler, Matthew / Nall, Clayton

Proceedings of the National Academy of Sciences of the United States of America

2022 Volume 119, Issue 12, Page(s) e2116870119

Abstract: SignificanceRecent political events show that members of extreme political groups support partisan violence, and survey evidence supposedly shows widespread public support. We show, however, that, after accounting for survey-based measurement error, ... ...

Abstract	SignificanceRecent political events show that members of extreme political groups support partisan violence, and survey evidence supposedly shows widespread public support. We show, however, that, after accounting for survey-based measurement error, support for partisan violence is far more limited. Prior estimates overstate support for political violence because of random responding by disengaged respondents and because of a reliance on hypothetical questions about violence in general instead of questions on specific acts of political violence. These same issues also cause the magnitude of the relationship between previously identified correlates and partisan violence to be overstated. As policy makers consider interventions designed to dampen support for violence, our results provide critical information about the magnitude of the problem.
MeSH term(s)	Politics ; Surveys and Questionnaires ; United States ; Violence
Language	English
Publishing date	2022-03-18
Publishing country	United States
Document type	Journal Article
ZDB-ID	209104-5
ISSN	1091-6490 ; 0027-8424
ISSN (online)	1091-6490
ISSN	0027-8424
DOI	10.1073/pnas.2116870119
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