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  1. Article ; Online: Bioactive agents from Parkia biglobosa (Jacq.) R.Br. ex G. Don bark extracts for health promotion and nutraceutical uses.

    Sut, Stefania / Dall'Acqua, Stefano / Sinan, Kouadio Ibrahime / Zengin, Gokhan / Uba, Abdullah Ibrahim / Etienne, Ouattara Katinan / Jugreet, Sharmeen / Mahomoodally, Mohamad Fawzi

    Journal of the science of food and agriculture

    2024  Volume 104, Issue 5, Page(s) 2820–2831

    Abstract: Background: Parkia biglobosa stem bark extracts were prepared using methanol, methanol 80%, water and ethyl acetate to investigate their phytochemical contents, as well as antioxidant and enzyme inhibitory properties.: Results: Liquid chromatography ( ...

    Abstract Background: Parkia biglobosa stem bark extracts were prepared using methanol, methanol 80%, water and ethyl acetate to investigate their phytochemical contents, as well as antioxidant and enzyme inhibitory properties.
    Results: Liquid chromatography (LC) quadrupole time-of-flight mass spectrometry (MS) and LC-MS
    Conclusion: The present study demonstrated that the stem bark extracts of P. biglobosa contains good amount of phytochemical and extracts present significant antioxidant, as well as reasonable enzyme inhibitory effects. Hence, these findings suggest that further studies can be performed on more specific biological targets and models of bioactivity to determine their safe usage as a nutraceutical or for the preparation functional foods. © 2023 The Authors. Journal of The Science of Food and Agriculture published by John Wiley & Sons Ltd on behalf of Society of Chemical Industry.
    MeSH term(s) Antioxidants/chemistry ; Plant Extracts/chemistry ; Butyrylcholinesterase ; Methanol/analysis ; Acetylcholinesterase ; Plant Bark/chemistry ; Phenols/chemistry ; Flavonoids/analysis ; Phytochemicals/pharmacology ; Phytochemicals/analysis ; Rutin/analysis ; Dietary Supplements/analysis ; Water/analysis ; Health Promotion ; Acetates
    Chemical Substances Antioxidants ; ethyl acetate (76845O8NMZ) ; Plant Extracts ; Butyrylcholinesterase (EC 3.1.1.8) ; Methanol (Y4S76JWI15) ; Acetylcholinesterase (EC 3.1.1.7) ; Phenols ; Flavonoids ; Phytochemicals ; Rutin (5G06TVY3R7) ; Water (059QF0KO0R) ; Acetates
    Language English
    Publishing date 2024-01-05
    Publishing country England
    Document type Journal Article
    ZDB-ID 184116-6
    ISSN 1097-0010 ; 0022-5142
    ISSN (online) 1097-0010
    ISSN 0022-5142
    DOI 10.1002/jsfa.13170
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 808: Show issues Location:
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    bis Jg. 2021: Bestellungen von Artikeln über das Online-Bestellformular
    ab Jg. 2022: Lesesaal (EG)

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  2. Article ; Online: Essential Oils Composition and Biological Activity of

    Eltayeb, Loai M H / Yagi, Sakina / Mohamed, Hanan M M / Zengin, Gokhan / Shariati, Mohammad Ali / Rebezov, Maksim / Uba, Abdullah Ibrahim / Lorenzo, Jose Manuel

    Molecules (Basel, Switzerland)

    2023  Volume 28, Issue 3

    Abstract: Generally, there are scant data about the constituents and eventually the biological activity of essential oils (EOs) from aromatic plants that grow naturally in Sudan. The present study aimed to determine the chemical composition, and antioxidant and ... ...

    Abstract Generally, there are scant data about the constituents and eventually the biological activity of essential oils (EOs) from aromatic plants that grow naturally in Sudan. The present study aimed to determine the chemical composition, and antioxidant and enzyme inhibitory activities of EO extracted from the fruit of
    MeSH term(s) Oils, Volatile/pharmacology ; Oils, Volatile/chemistry ; Lavandula/chemistry ; Chamaecyparis/chemistry ; Chrysopogon ; Sudan ; Butyrylcholinesterase ; Monoterpenes ; Antioxidants/pharmacology ; Antioxidants/chemistry ; Sesquiterpenes/pharmacology
    Chemical Substances Oils, Volatile ; Butyrylcholinesterase (EC 3.1.1.8) ; Monoterpenes ; Antioxidants ; Sesquiterpenes
    Language English
    Publishing date 2023-01-19
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 1413402-0
    ISSN 1420-3049 ; 1431-5165 ; 1420-3049
    ISSN (online) 1420-3049
    ISSN 1431-5165 ; 1420-3049
    DOI 10.3390/molecules28031005
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    Zs.MO 81: Show issues

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  3. Article ; Online: Synthesis, molecular modeling, in vivo study and anticancer activity against prostate cancer of (+) (S)-naproxen derivatives.

    Birgül, Kaan / Yıldırım, Yeliz / Karasulu, H Yeşim / Karasulu, Ercüment / Uba, Abdullah Ibrahim / Yelekçi, Kemal / Bekçi, Hatice / Cumaoğlu, Ahmet / Kabasakal, Levent / Yılmaz, Özgür / Küçükgüzel, Ş Güniz

    European journal of medicinal chemistry

    2020  Volume 208, Page(s) 112841

    Abstract: In this study, (S)-naproxen thiosemicarbazides (3a-d), 1,2,4-triazoles (4a-c), triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d, 4a and 5a-p) were confirmed by FT-IR, ...

    Abstract In this study, (S)-naproxen thiosemicarbazides (3a-d), 1,2,4-triazoles (4a-c), triazole-thioether hybride compounds (5a-p) were synthesized and their structures (3a, 3d, 4a and 5a-p) were confirmed by FT-IR,
    MeSH term(s) Animals ; Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/metabolism ; Antineoplastic Agents/therapeutic use ; Apoptosis/drug effects ; Cell Line, Tumor ; Drug Screening Assays, Antitumor ; Enzyme Inhibitors/chemical synthesis ; Enzyme Inhibitors/metabolism ; Enzyme Inhibitors/therapeutic use ; Humans ; Male ; Methionyl Aminopeptidases/antagonists & inhibitors ; Methionyl Aminopeptidases/metabolism ; Mice, Nude ; Molecular Docking Simulation ; Molecular Dynamics Simulation ; Molecular Structure ; Naproxen/analogs & derivatives ; Naproxen/metabolism ; Naproxen/therapeutic use ; Prostatic Neoplasms/drug therapy ; Protein Binding ; Stereoisomerism ; Structure-Activity Relationship
    Chemical Substances Antineoplastic Agents ; Enzyme Inhibitors ; Naproxen (57Y76R9ATQ) ; METAP2 protein, human (EC 3.4.11.18) ; Metap2 protein, mouse (EC 3.4.11.18) ; Methionyl Aminopeptidases (EC 3.4.11.18)
    Language English
    Publishing date 2020-09-16
    Publishing country France
    Document type Journal Article
    ZDB-ID 188597-2
    ISSN 1768-3254 ; 0009-4374 ; 0223-5234
    ISSN (online) 1768-3254
    ISSN 0009-4374 ; 0223-5234
    DOI 10.1016/j.ejmech.2020.112841
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 784: Show issues Location:
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