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  1. Article ; Online: Implementing online position monitoring for prostate radiotherapy using an in-house position monitoring system: User experience and impact on workforce.

    Cardoso, Michael / Sidhom, Mark / Udovitch, Mark / Young, Tony / Arumugam, Sankar

    Journal of medical imaging and radiation oncology

    2022  Volume 67, Issue 1, Page(s) 111–118

    Abstract: Introduction: To evaluate the feasibility of prostate intrafraction motion monitoring using the SeedTracker real-time image guidance system in order to improve targeting accuracy in prostate radiotherapy.: Methods: SeedTracker was used to monitor ... ...

    Abstract Introduction: To evaluate the feasibility of prostate intrafraction motion monitoring using the SeedTracker real-time image guidance system in order to improve targeting accuracy in prostate radiotherapy.
    Methods: SeedTracker was used to monitor prostate gold fiducial seeds with kV x-ray imaging during radiotherapy in 30 patients. Feedback from radiation therapists was collected via the use of a user evaluation form. The impact on treatment time was established by using a record and verify system. The effective dose and a risk of exposure-induced cancer death (REID) were estimated for a 60-year-old patient when using the SeedTracker system.
    Results: A total of 22 radiation therapists completed user evaluation forms. The time taken to prepare a reference data set for one patient varied with three (13.6%) radiation therapists taking less than 2 min, 10 (45.5%) between 2 and 4 min, eight (36.4%) between 4 and 6 min and one (4.5%) between 6 and 8 min. The useability of the SeedTracker system was reported as 'easy' by 21 (95.5%) radiation therapists and 'hard' by 1 (4.5%) radiation therapist. Mean treatment time changed from 6 to 7 min with prostate-only radiotherapy treatment and from 6.9 to 10.2 min with prostate and whole pelvis radiotherapy treatments. The maximum effective dose with the SeedTracker was 1.6276 mSv, and increase in REID was 0.007%.
    Conclusion: The SeedTracker real-time image guidance system is a feasible tool to use in radiotherapy departments to monitor and correct for prostate intrafraction motion.
    MeSH term(s) Male ; Humans ; Middle Aged ; Prostate ; Prostatic Neoplasms/radiotherapy ; Fiducial Markers ; Radiotherapy, Image-Guided/methods ; Workforce ; Radiotherapy Planning, Computer-Assisted/methods ; Radiotherapy, Intensity-Modulated/methods ; Movement
    Language English
    Publishing date 2022-12-20
    Publishing country Australia
    Document type Case Reports ; Journal Article
    ZDB-ID 2389687-5
    ISSN 1754-9485 ; 1440-1673 ; 1754-9477 ; 0004-8461
    ISSN (online) 1754-9485 ; 1440-1673
    ISSN 1754-9477 ; 0004-8461
    DOI 10.1111/1754-9485.13499
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  2. Article: Assessment of intrafraction motion and its dosimetric impact on prostate radiotherapy using an in-house developed position monitoring system.

    Arumugam, Sankar / Young, Tony / Do, Viet / Chlap, Phillip / Tawfik, Christine / Udovitch, Mark / Wong, Karen / Sidhom, Mark

    Frontiers in oncology

    2023  Volume 13, Page(s) 1082391

    Abstract: Purpose: To implement an in-house developed position monitoring software, SeedTracker, for conventional fractionation prostate radiotherapy, and study the effect on dosimetric impact and intrafraction motion.: Methods: Thirty definitive prostate ... ...

    Abstract Purpose: To implement an in-house developed position monitoring software, SeedTracker, for conventional fractionation prostate radiotherapy, and study the effect on dosimetric impact and intrafraction motion.
    Methods: Thirty definitive prostate radiotherapy patients with implanted fiducial markers were included in the study. All patients were treated with VMAT technique and plans were generated using the Pinnacle planning system using the 6MV beam model for Elekta linear accelerator. The target dose of 60 Gy in 20 fractions was prescribed for 29 of 30 patients, and one patient was treated with the target dose of 78 Gy in 39 fractions. The SeedTracker position monitoring system, which uses the x-ray images acquired during treatment delivery in the Elekta linear accelerator and associated XVI system, was used for online prostate position monitoring. The position tolerance for online verification was progressively reduced from 5 mm, 4 mm, and to 3 mm in 10 patient cohorts to effectively manage the treatment interruptions resulting from intrafraction motion in routine clinical practice. The delivered dose to target volumes and organs at risk in each of the treatment fractions was assessed by incorporating the observed target positions into the original treatment plan.
    Results: In 27 of 30 patients, at least one gating event was observed, with a total of 177 occurrences of position deviation detected in 146 of 619 treatment fractions. In 5 mm, 4 mm, and 3 mm position tolerance cohorts, the position deviations were observed in 13%, 24%, and 33% of treatment fractions, respectively. Overall, the mean (range) deviation of -0.4 (-7.2 to 5.3) mm, -0.9 (-6.1 to 15.6) mm, and -1.7 (-7.0 to 6.1) mm was observed in Left-Right, Anterior-Posterior, and Superior-Inferior directions, respectively. The prostate CTV D99 would have been reduced by a maximum value of 1.3 Gy compared to the planned dose if position deviations were uncorrected, but with corrections, it was 0.3 Gy. Similarly, PTV D98 would have been reduced by a maximum value of 7.6 Gy uncorrected, with this difference reduced to 2.2 Gy with correction. The V60 to the rectum increased by a maximum of 1.0% uncorrected, which was reduced to 0.5%.
    Conclusion: Online target position monitoring for conventional fractionation prostate radiotherapy was successfully implemented on a standard Linear accelerator using an in-house developed position monitoring software, with an improvement in resultant dose to prostate target volume.
    Language English
    Publishing date 2023-07-14
    Publishing country Switzerland
    Document type Journal Article
    ZDB-ID 2649216-7
    ISSN 2234-943X
    ISSN 2234-943X
    DOI 10.3389/fonc.2023.1082391
    Database MEDical Literature Analysis and Retrieval System OnLINE

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  3. Article: Quantifying and Assessing the Dosimetric Impact of Changing Gas Volumes Throughout the Course of VMAT Radiation Therapy of Upper Gastrointestinal Tumors.

    Scott, Joshua / Dundas, Kylie / Surjan, Yolanda / King, Odette / Arumugam, Sankar / Deshpande, Shrikant / Udovitch, Mark / Lee, Mark

    Advances in radiation oncology

    2021  Volume 6, Issue 3, Page(s) 100650

    Abstract: Purpose: This retrospective patient study assessed the consistency of abdominal gas presence throughout radiation therapy for patients with upper gastrointestinal cancer and determined the impact of variations in gas volume on the calculated dose ... ...

    Abstract Purpose: This retrospective patient study assessed the consistency of abdominal gas presence throughout radiation therapy for patients with upper gastrointestinal cancer and determined the impact of variations in gas volume on the calculated dose distribution of volumetric modulated arc therapy.
    Methods and materials: Eight patients with pancreatic cancer were included for analysis. A plan library consisting of 3 reference plans per patient (Ref
    Results: There was a significant decrease in gas present from CT to treatment CBCT, with a mean decrease in volume of 48.6% for the entire cohort. Dosimetrically, all accumulated target and organ-at-risk parameters, aside from the kidneys, exhibited the smallest mean deviation from the Ref
    Conclusions: Significant variation in gas volumes from CT to treatment can occur throughout volumetric modulated arc therapy for pancreatic cancer. Through the use of a plan library, it was determined that initial assessment of a patient's treatment plan with an assigned gas density of 0.0 provided the most accurate prediction of the accumulated dose.
    Language English
    Publishing date 2021-01-17
    Publishing country United States
    Document type Journal Article
    ISSN 2452-1094
    ISSN 2452-1094
    DOI 10.1016/j.adro.2021.100650
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  4. Article ; Online: Variable angle stereo imaging for rapid patient position correction in an in-house real-time position monitoring system.

    Arumugam, Sankar / Sidhom, Mark / Truant, Daniel / Xing, Aitang / Udovitch, Mark / Holloway, Lois

    Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)

    2017  Volume 33, Page(s) 170–178

    Abstract: Purpose: To develop and validate a variable angle stereo image based position correction methodology in an X-ray based in-house online position monitoring system.: Materials and methods: A stereo imaging module that enables 3D position determination ... ...

    Abstract Purpose: To develop and validate a variable angle stereo image based position correction methodology in an X-ray based in-house online position monitoring system.
    Materials and methods: A stereo imaging module that enables 3D position determination and couch correction of the patient based on images acquired at any arbitrary angle and arbitrary angular separation was developed and incorporated to the in-house SeedTracker real-time position monitoring system. The accuracy of the developed system was studied by imaging an anthropomorphic phantom implanted with radiopaque markers set to known offset positions from its reference position in an Elekta linear accelerator (LA) and associated XVI imaging system. The accuracy of the system was further validated using CBCT data set from 10 prostate SBRT patients. The time gains achieved with the stereo image based position correction was compared with the manual matching of seed positions in Digitally Reconstructed Radiographs (DRRs) and kV images in the Mosaiq record and verify system.
    Results: Based on phantom and patient CBCT dataset study stereo imaging module implemented in the SeedTracker shown to have an accuracy of 0.1(σ=0.5)mm in detecting the 3D position offset. The time comparison study showed that stereo image based methodology implemented in SeedTracker was a minimum of 80(4)s faster than the manual method implemented in Mosaiq R&V system with a maximum time saving of 146(6)s.
    Conclusion: The variable angle stereo image based position correction method was shown to be accurate and faster than the standard manual DRR-kV image based correction approach, leading to more efficient treatment.
    MeSH term(s) Fiducial Markers ; Humans ; Imaging, Three-Dimensional ; Patient Positioning/methods ; Time Factors
    Language English
    Publishing date 2017-01
    Publishing country Italy
    Document type Journal Article
    ZDB-ID 1122650-x
    ISSN 1724-191X ; 1120-1797
    ISSN (online) 1724-191X
    ISSN 1120-1797
    DOI 10.1016/j.ejmp.2016.12.014
    Database MEDical Literature Analysis and Retrieval System OnLINE

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    In stock of ZB MED Cologne/Königswinter

    Zs.B 2941: Show issues Location:
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