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  1. Article ; Online: Etanercept-induced erythema nodosum in a patient with rheumatoid arthritis: Case report and literature review.

    Kurokami, Yu / Ueda-Hayakawa, Ikuko / Fujimoto, Manabu

    The Journal of dermatology

    2022  Volume 50, Issue 3, Page(s) e108–e109

    MeSH term(s) Humans ; Etanercept/adverse effects ; Erythema Nodosum/chemically induced ; Erythema Nodosum/diagnosis ; Erythema Nodosum/drug therapy ; Arthritis, Rheumatoid/drug therapy ; Arthritis
    Chemical Substances Etanercept (OP401G7OJC)
    Language English
    Publishing date 2022-11-22
    Publishing country England
    Document type Review ; Case Reports ; Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16636
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  2. Article ; Online: Age distribution and prevalence in different age groups of four myositis-specific autoantibodies, including anti-ARS, anti-MDA5, anti-Mi-2, and anti-TIF1γ antibodies.

    Ueda-Hayakawa, Ikuko / Tonomura, Kyoko / Maekawa, Aya / Kaneda, Emi / Arase, Noriko / Fujimoto, Manabu

    The Journal of dermatology

    2023  Volume 50, Issue 8, Page(s) 1058–1062

    Abstract: We accumulated the demographic information and analyzed the prevalence of myositis-specific antibodies (MSAs) in a large cohort across Japan as standard testing for MSAs becomes more widely available. This retrospective, observational, cohort study ... ...

    Abstract We accumulated the demographic information and analyzed the prevalence of myositis-specific antibodies (MSAs) in a large cohort across Japan as standard testing for MSAs becomes more widely available. This retrospective, observational, cohort study analyzed the records of individuals aged 0-99 years who are tested for serum MSAs at SRL Incorporation from January 2014 to April 2020 across Japan. An enzyme-linked immunosorbent assay testing was applied to determine the presence of anti-aminoacyl tRNA synthetase (anti-ARS), anti-Mi-2, anti-melanoma differentiation-associated gene 5 (anti-MDA5), or anti-transcriptional intermediary factor 1-γ (anti-TIF1γ) (Medical and Biological Laboratories). Anti-TIF1γ antibody was detected more in male patients than female patients. In contrast, women were predominant in patients with other MSAs. More than half of the anti-ARS or anti-TIF1γ antibody-positive patients were over 60 years old, although anti-MDA5 or anti-Mi-2-positive patients were mostly under <60 years old. Anti-MDA5 antibody-positive patients were mostly aged 40-59 years, while other MSA groups were mostly 60-79 years. Anti-MDA5 antibody was detected most frequently in the age range of 0-29 years. Anti-TIF1γ antibody was the second most commonly detected autoantibody in the age range of 0-19 years. Anti-ARS antibody was the most frequently detected autoantibody after the age of 30 years, and the frequency of anti-ARS gradually increased at more advanced ages. The second and third most detected autoantibodies were anti-MDA5 and anti-TIF1γ, respectively, in ages 30-79 years. We performed a nationwide >3-year evaluation of MSA detection in a routine diagnostic setting. This paper provides clinical images concerning the relationship between four MSA types and the distribution of sex and age in a large population.
    MeSH term(s) Adolescent ; Adult ; Child ; Child, Preschool ; Female ; Humans ; Infant ; Infant, Newborn ; Male ; Middle Aged ; Young Adult ; Age Distribution ; Amino Acyl-tRNA Synthetases ; Autoantibodies ; Cohort Studies ; Dermatomyositis/diagnosis ; Dermatomyositis/epidemiology ; Myositis/diagnosis ; Myositis/epidemiology ; Prevalence ; Retrospective Studies ; Aged
    Chemical Substances Amino Acyl-tRNA Synthetases (EC 6.1.1.-) ; Autoantibodies ; Mi-2 antibodies
    Language English
    Publishing date 2023-03-08
    Publishing country England
    Document type Observational Study ; Journal Article
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16772
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  3. Article ; Online: Association between periungual changes and myositis-specific autoantibodies in patients with idiopathic inflammatory myopathies: A retrospective cohort study.

    Ueda-Hayakawa, Ikuko / Maekawa, Aya / Tonomura, Kyoko / Kaneda, Emi / Yamazaki, Yuriko / Arase, Noriko / Fujimoto, Manabu

    Journal of the American Academy of Dermatology

    2024  

    Language English
    Publishing date 2024-05-02
    Publishing country United States
    Document type Journal Article
    ZDB-ID 603641-7
    ISSN 1097-6787 ; 0190-9622
    ISSN (online) 1097-6787
    ISSN 0190-9622
    DOI 10.1016/j.jaad.2024.03.052
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  4. Article ; Online: Exacerbation of livedoid vasculopathy after coronavirus disease 2019.

    Kawabe, Ryoko / Tonomura, Kyoko / Kotobuki, Yorihisa / Ueda-Hayakawa, Ikuko / Murota, Hiroyuki / Fujimoto, Manabu

    European journal of dermatology : EJD

    2022  Volume 32, Issue 1, Page(s) 129–131

    Title translation Exacerbation of livedoid vasculopathy after coronavirus disease 2019.
    MeSH term(s) COVID-19/complications ; Humans ; Livedo Reticularis/etiology ; Livedoid Vasculopathy
    Language English
    Publishing date 2022-05-23
    Publishing country France
    Document type Journal Article
    ZDB-ID 1128666-0
    ISSN 1952-4013 ; 1167-1122
    ISSN (online) 1952-4013
    ISSN 1167-1122
    DOI 10.1684/ejd.2022.4200
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  5. Article ; Online: A case of erosive pustular dermatosis of the scalp following bullous pemphigoid in a hematopoietic stem cell transplant recipient.

    Yamashita, Chigusa / Arase, Noriko / Fukushima, Kentaro / Ueda-Hayakawa, Ikuko / Tonomura, Kyoko / Tanemura, Atsushi / Sakai, Hiroshi / Fujimoto, Manabu

    The Journal of dermatology

    2023  Volume 50, Issue 7, Page(s) e218–e219

    MeSH term(s) Humans ; Pemphigoid, Bullous/diagnosis ; Pemphigoid, Bullous/drug therapy ; Pemphigoid, Bullous/etiology ; Scalp ; Scalp Dermatoses/diagnosis ; Scalp Dermatoses/etiology ; Hematopoietic Stem Cell Transplantation/adverse effects
    Language English
    Publishing date 2023-02-16
    Publishing country England
    Document type Case Reports ; Letter ; Research Support, Non-U.S. Gov't
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16743
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  6. Article ; Online: Case of anti-Mi-2 antibody-positive dermatomyositis with predictable onset before the development of muscle symptoms.

    Kaneda, Emi / Tonomura, Kyoko / Kotobuki, Yorihisa / Ueda-Hayakawa, Ikuko / Tasaka, Kanako / Fujimoto, Manabu

    The Journal of dermatology

    2021  Volume 49, Issue 3, Page(s) e104–e105

    MeSH term(s) Autoantibodies ; Dermatomyositis/complications ; Dermatomyositis/diagnosis ; Humans ; Muscles
    Chemical Substances Autoantibodies ; Mi-2 antibodies
    Language English
    Publishing date 2021-11-28
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16249
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  7. Article ; Online: A case of palisaded neutrophilic and granulomatous dermatitis associated with systemic lupus erythematosus presenting with pustules.

    Tajima, Aki / Yamazaki, Fumikazu / Huynh, Trang Nguyen Mai / Ueda-Hayakawa, Ikuko / Kishimoto, Izumi / Itsukage, Shizu / Kume, Noriko / Tanizaki, Hideaki

    The Journal of dermatology

    2022  Volume 50, Issue 2, Page(s) 262–265

    Abstract: Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a relatively rare skin disease that is characterized by a reactive granulomatous histopathological pattern and is often associated with systemic autoimmune diseases. We encountered a case of ... ...

    Abstract Palisaded neutrophilic and granulomatous dermatitis (PNGD) is a relatively rare skin disease that is characterized by a reactive granulomatous histopathological pattern and is often associated with systemic autoimmune diseases. We encountered a case of PNGD that presented with pustules, although the prototypical clinical presentation of PNGD is mainly erythema and papules. Here, this rare case of PNGD with pustules is presented and discussed in relation to the relevant literature.
    MeSH term(s) Humans ; Dermatitis/etiology ; Dermatitis/complications ; Skin Diseases/pathology ; Skin/pathology ; Lupus Erythematosus, Systemic/complications ; Lupus Erythematosus, Systemic/diagnosis ; Lupus Erythematosus, Systemic/pathology ; Blister/pathology
    Language English
    Publishing date 2022-10-11
    Publishing country England
    Document type Case Reports ; Journal Article
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16605
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  8. Article ; Online: A case of anti-RNA polymerase III antibody-positive systemic sclerosis with generalized morphea-like lesions correlated with elevation of peripheral eosinophil counts.

    Sasaoka, Yusuke / Kotobuki, Yorihisa / Fujimoto, Rai / Tonomura, Kyoko / Nakagawa, Yukinobu / Ueda-Hayakawa, Ikuko / Tani, Mamori / Fujimoto, Manabu

    The Journal of dermatology

    2022  Volume 49, Issue 11, Page(s) e417–e418

    MeSH term(s) Humans ; Scleroderma, Localized/pathology ; RNA Polymerase III ; Eosinophils/pathology ; Scleroderma, Systemic/pathology ; Leukocyte Count
    Chemical Substances RNA Polymerase III (EC 2.7.7.6)
    Language English
    Publishing date 2022-06-25
    Publishing country England
    Document type Case Reports ; Letter
    ZDB-ID 800103-0
    ISSN 1346-8138 ; 0385-2407
    ISSN (online) 1346-8138
    ISSN 0385-2407
    DOI 10.1111/1346-8138.16496
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  9. Article ; Online: Erratum to "Clinical and laboratory parameters predicting cancer in dermatomyositis patients with anti-TIF1γ antibodies" [J. Dermatol. Sci. 104 (2021) 177-84].

    Thi My Ly, Nhung / Ma, Ni / Ueda-Hayakawa, Ikuko / Thi Hong Nguyen, Chuyen / Anada, Reiko / Okamoto, Hiroyuki / Fujimoto, Manabu

    Journal of dermatological science

    2022  Volume 107, Issue 1, Page(s) 56

    Language English
    Publishing date 2022-07-08
    Publishing country Netherlands
    Document type Published Erratum
    ZDB-ID 1024446-3
    ISSN 1873-569X ; 0923-1811
    ISSN (online) 1873-569X
    ISSN 0923-1811
    DOI 10.1016/j.jdermsci.2022.06.003
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  10. Article ; Online: Exploring the imbalance of circulating follicular helper CD4

    Ly, Nhung Thi My / Ueda-Hayakawa, Ikuko / Nguyen, Chuyen Thi Hong / Okamoto, Hiroyuki

    Journal of dermatological science

    2020  Volume 97, Issue 3, Page(s) 216–224

    Abstract: Background: Sarcoidosis is a systemic granulomatous disease characterized by the combination of Th1 and Th17 responses. Recently, several arguments have suggested a potential involvement of B cells as well as T cells in the pathogenesis of sarcoidosis. ... ...

    Abstract Background: Sarcoidosis is a systemic granulomatous disease characterized by the combination of Th1 and Th17 responses. Recently, several arguments have suggested a potential involvement of B cells as well as T cells in the pathogenesis of sarcoidosis. Follicular helper CD4
    Objective: We sought to explore the status of T
    Methods: T
    Results: The proportion of circulating T
    Conclusion: We herein describe a decrease of circulating T
    MeSH term(s) Adult ; Aged ; Aged, 80 and over ; B-Lymphocytes/immunology ; Biopsy ; CD4 Lymphocyte Count ; Cell Differentiation/immunology ; Cell Movement/immunology ; Female ; Humans ; Interleukin-17/metabolism ; Male ; Middle Aged ; Sarcoidosis/blood ; Sarcoidosis/immunology ; Sarcoidosis/pathology ; Skin/immunology ; Skin/pathology ; T Follicular Helper Cells/immunology ; T Follicular Helper Cells/metabolism ; Th17 Cells/immunology
    Chemical Substances Interleukin-17
    Language English
    Publishing date 2020-02-08
    Publishing country Netherlands
    Document type Journal Article ; Observational Study
    ZDB-ID 1024446-3
    ISSN 1873-569X ; 0923-1811
    ISSN (online) 1873-569X
    ISSN 0923-1811
    DOI 10.1016/j.jdermsci.2020.02.002
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